-
1
-
-
56549110631
-
Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: A randomised, single-blind, multicentre trial
-
Abdulla, S., et al. 2008. Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial. Lancet 372:1819-1827.
-
(2008)
Lancet
, vol.372
, pp. 1819-1827
-
-
Abdulla, S.1
-
2
-
-
52549112649
-
Likelihood based approaches to handling data below the quantification limit using NONMEM VI
-
Ahn, J. E., M. O. Karlsson, A. Dunne, and T. M. Ludden. 2008. Likelihood based approaches to handling data below the quantification limit using NONMEM VI. J. Pharmacokinet. Pharmacodyn. 35:401-421.
-
(2008)
J. Pharmacokinet. Pharmacodyn.
, vol.35
, pp. 401-421
-
-
Ahn, J.E.1
Karlsson, M.O.2
Dunne, A.3
Ludden, T.M.4
-
3
-
-
41149180911
-
Mechanism-based concepts of size and maturity in pharmacokinetics
-
DOI 10.1146/annurev.pharmtox.48.113006.094708
-
Anderson, B. J., and N. H. Holford. 2008. Mechanism-based concepts of size and maturity in pharmacokinetics. Annu. Rev. Pharmacol. Toxicol. 48:303-332. (Pubitemid 351738156)
-
(2008)
Annual Review of Pharmacology and Toxicology
, vol.48
, pp. 303-332
-
-
Anderson, B.J.1
Holford, N.H.G.2
-
4
-
-
33846945094
-
How much fat is necessary to optimize lumefantrine oral bioavailability?
-
Ashley, E. A., et al. 2007. How much fat is necessary to optimize lumefantrine oral bioavailability? Trop. Med. Int. Health 12:195-200.
-
(2007)
Trop. Med. Int. Health
, vol.12
, pp. 195-200
-
-
Ashley, E.A.1
-
5
-
-
33846952552
-
Pharmacokinetic study of artemether-lumefantrine given once daily for the treatment of uncomplicated multidrug-resistant falciparum malaria
-
Ashley, E. A., et al. 2007. Pharmacokinetic study of artemether- lumefantrine given once daily for the treatment of uncomplicated multidrug-resistant falciparum malaria. Trop. Med. Int. Health 12:201-208.
-
(2007)
Trop. Med. Int. Health
, vol.12
, pp. 201-208
-
-
Ashley, E.A.1
-
6
-
-
33845526406
-
Sulfadoxine-pyrimethamine pharmacokinetics in malaria: Pediatric dosing implications
-
DOI 10.1016/j.clpt.2006.08.016, PII S0009923606003535
-
Barnes, K. I., et al. 2006. Sulfadoxine-pyrimethamine pharmacokinetics in malaria: pediatric dosing implications. Clin. Pharmacol. Ther. 80:582-596. (Pubitemid 44920218)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.80
, Issue.6
, pp. 582-596
-
-
Barnes, K.I.1
Little, F.2
Smith, P.J.3
Evans, A.4
Watkins, W.M.5
White, N.J.6
-
7
-
-
0029868179
-
Selective high-performance liquid chromatographic determination of artesunate and alpha- and β-dihydroartemisinin in patients with falciparum malaria
-
DOI 10.1016/0378-4347(95)00428-9
-
Batty, K. T., et al. 1996. Selective high-performance liquid chromatographic determination of artesunate and alpha- and beta- dihydroartemisinin in patients with falciparum malaria. J. Chromatogr. B Biomed. Appl. 677:345-350. (Pubitemid 26106005)
-
(1996)
Journal of Chromatography B: Biomedical Applications
, vol.677
, Issue.2
, pp. 345-350
-
-
Batty, K.T.1
Davis, T.M.E.2
Thu, L.T.A.3
Binh, T.Q.4
Anh, T.K.5
Ilett, K.F.6
-
8
-
-
78951473582
-
Population pharmacokinetics of sulfadoxine and pyrimethamine in Malawian children with malaria
-
Bell, D. J., et al. 2011. Population pharmacokinetics of sulfadoxine and pyrimethamine in Malawian children with malaria. Clin. Pharmacol. Ther. 89:268-275.
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 268-275
-
-
Bell, D.J.1
-
9
-
-
68249141539
-
Handling data below the limit of quantification in mixed effect models
-
Bergstrand, M., and M. O. Karlsson. 2009. Handling data below the limit of quantification in mixed effect models. AAPS J. 11:371-380.
-
(2009)
AAPS J.
, vol.11
, pp. 371-380
-
-
Bergstrand, M.1
Karlsson, M.O.2
-
10
-
-
84855186854
-
A comparison of methods for handling of data below the limit of quantification in NONMEM VI
-
abstr. 1201
-
Bergstrand, M., E. Plan, M. C. Kjellsson, and M. O. Karlsson. 2007. A comparison of methods for handling of data below the limit of quantification in NONMEM VI, abstr. 1201. Abstr. 16th Annu. Meet. Popul. Approach Group Eur., Copenhagen, Denmark, 13 to 15 June 2007. http://www.page-meeting.org/pdf-assets/ 6427-Poster-PAGE2007-070607-final.pdf.
-
(2007)
Abstr. 16th Annu. Meet. Popul. Approach Group Eur., Copenhagen, Denmark, 13 to 15 June 2007
-
-
Bergstrand, M.1
Plan, E.2
Kjellsson, M.C.3
Karlsson, M.O.4
-
11
-
-
0033844418
-
Cardiac effects of co-artemether (artemether/lumefantrine) and mefloquine given alone or in combination to healthy volunteers
-
Bindschedler, M., et al. 2000. Cardiac effects of co-artemether (artemether/lumefantrine) and mefloquine given alone or in combination to healthy volunteers. Eur. J. Clin. Pharmacol. 56:375-381.
-
(2000)
Eur. J. Clin. Pharmacol.
, vol.56
, pp. 375-381
-
-
Bindschedler, M.1
-
12
-
-
0031753648
-
Population pharmacokinetics and therapeutic response of CGP 56697 (artemether + benflumetol) in malaria patients
-
DOI 10.1046/j.1365-2125.1998.00830.x
-
Ezzet, F., R. Mull, and J. Karbwang. 1998. Population pharmacokinetics and therapeutic response of CGP 56697 (artemether + benflumetol) in malaria patients. Br. J. Clin. Pharmacol. 46:553-561. (Pubitemid 28522119)
-
(1998)
British Journal of Clinical Pharmacology
, vol.46
, Issue.6
, pp. 553-561
-
-
Ezzet, F.1
Karbwang, J.2
-
13
-
-
0033998085
-
Pharmacokinetics and pharmacodynamics of lumefantrine (benflumetol) in acute falciparum malaria
-
DOI 10.1128/AAC.44.3.697-704.2000
-
Ezzet, F., M. van Vugt, F. Nosten, S. Looareesuwan, and N. J. White. 2000. Pharmacokinetics and pharmacodynamics of lumefantrine (benflumetol) in acute falciparum malaria. Antimicrob. Agents Chemother. 44:697-704. (Pubitemid 30117964)
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, Issue.3
, pp. 697-704
-
-
Ezzet, F.1
Van Vugt, M.2
Nosten, F.3
Looareesuwan, S.4
White, N.J.5
-
14
-
-
68049121902
-
Lopinavir/ritonavir affects pharmacokinetic exposure of artemether/lumefantrine in HIV-uninfected healthy volunteers
-
German, P., et al. 2009. Lopinavir/ritonavir affects pharmacokinetic exposure of artemether/lumefantrine in HIV-uninfected healthy volunteers. J. Acquir. Immune Defic. Syndr. 51:424-429.
-
(2009)
J. Acquir. Immune Defic. Syndr.
, vol.51
, pp. 424-429
-
-
German, P.1
-
15
-
-
41249095896
-
Treatment of acute uncomplicated falciparum malaria with artemether-lumefantrine in non-immune populations: A safety, efficacy, and pharmacokinetic study
-
Hatz, C., et al. 2008. Treatment of acute uncomplicated falciparum malaria with artemether-lumefantrine in nonimmune populations: a safety, efficacy, and pharmacokinetic study. Am. J. Trop. Med. Hyg. 78:241-247. (Pubitemid 351844558)
-
(2008)
American Journal of Tropical Medicine and Hygiene
, vol.78
, Issue.2
, pp. 241-247
-
-
Hatz, C.1
Soto, J.2
Nothdurft, H.D.3
Zoller, T.4
Weitzel, T.5
Loutan, L.6
Bricaire, F.7
Gay, F.8
Burchard, G.-D.9
Andriano, K.10
Lefevre, G.11
De Palacios, P.I.12
Genton, B.13
-
16
-
-
78049272272
-
Population pharmacokinetics and pharmacodynamics of artemether and lumefantrine during combination treatment in children with uncomplicated falciparum malaria in Tanzania
-
Hietala, S. F., et al. 2010. Population pharmacokinetics and pharmacodynamics of artemether and lumefantrine during combination treatment in children with uncomplicated falciparum malaria in Tanzania. Antimicrob. Agents Chemother. 54:4780-4788.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 4780-4788
-
-
Hietala, S.F.1
-
17
-
-
35848952270
-
Conditional weighted residuals (CWRES): A model diagnostic for the FOCE method
-
DOI 10.1007/s11095-007-9361-x
-
Hooker, A. C., C. E. Staatz, and M. O. Karlsson. 2007. Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method. Pharm. Res. 24:2187-2197. (Pubitemid 350060706)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.12
, pp. 2187-2197
-
-
Hooker, A.C.1
Staatz, C.E.2
Karlsson, M.O.3
-
18
-
-
57749116211
-
A trial of combination antimalarial therapies in children from Papua New Guinea
-
Karunajeewa, H. A., et al. 2008. A trial of combination antimalarial therapies in children from Papua New Guinea. N. Engl. J. Med. 359:2545-2557.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 2545-2557
-
-
Karunajeewa, H.A.1
-
19
-
-
0036785445
-
Interaction trial between artemether-lumefantrine (Riamet) and quinine in healthy subjects
-
Lefevre, G., et al. 2002. Interaction trial between artemether- lumefantrine (Riamet) and quinine in healthy subjects. J. Clin. Pharmacol. 42:1147-1158.
-
(2002)
J. Clin. Pharmacol.
, vol.42
, pp. 1147-1158
-
-
Lefevre, G.1
-
20
-
-
0036435747
-
Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet) with concomitant administration of ketoconazole in healthy subjects
-
DOI 10.1046/j.1365-2125.2002.01696.x
-
Lefevre, G., et al. 2002. Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet) with concomitant administration of ketoconazole in healthy subjects. Br. J. Clin. Pharmacol. 54:485-492. (Pubitemid 35356874)
-
(2002)
British Journal of Clinical Pharmacology
, vol.54
, Issue.5
, pp. 485-492
-
-
Lefevre, G.1
Carpenter, P.2
Souppart, C.3
Schmidli, H.4
McClean, M.5
Stypinski, D.6
-
21
-
-
0034946077
-
A clinical and pharmacokinetic trial of six doses of artemether- lumefantrine for multidrug-resistant Plasmodium falciparum malaria in Thailand
-
Lefevre, G., et al. 2001. A clinical and pharmacokinetic trial of six doses of artemether-lumefantrine for multidrug-resistant Plasmodium falciparum malaria in Thailand. Am. J. Trop. Med. Hyg. 64:247-256.
-
(2001)
Am. J. Trop. Med. Hyg.
, vol.64
, pp. 247-256
-
-
Lefevre, G.1
-
22
-
-
0033380993
-
Clinical pharmacokinetics of artemether and lumefantrine (Riamet)
-
Lefevre, G., and M. S. Thomsen. 1999. Clinical pharmacokinetics of artemether and lumefantrine (Riamet (R)). Clin. Drug Investig. 18:467-480. (Pubitemid 30047534)
-
(1999)
Clinical Drug Investigation
, vol.18
, Issue.6
, pp. 467-480
-
-
Lefevre, G.1
Thomsen, M.S.2
-
23
-
-
0037663202
-
Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS
-
DOI 10.1021/ac020361s
-
Matuszewski, B. K., M. L. Constanzer, and C. M. Chavez-Eng. 2003. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal. Chem. 75:3019-3030. (Pubitemid 36830428)
-
(2003)
Analytical Chemistry
, vol.75
, Issue.13
, pp. 3019-3030
-
-
Matuszewski, B.K.1
Constanzer, M.L.2
Chavez-Eng, C.M.3
-
24
-
-
33751253121
-
The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria
-
DOI 10.1007/s00228-006-0199-7
-
McGready, R., et al. 2006. The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria. Eur. J. Clin. Pharmacol. 62:1021-1031. (Pubitemid 44786494)
-
(2006)
European Journal of Clinical Pharmacology
, vol.62
, Issue.12
, pp. 1021-1031
-
-
McGready, R.1
Stepniewska, K.2
Lindegardh, N.3
Ashley, E.A.4
La, Y.5
Singhasivanon, P.6
White, N.J.7
Nosten, F.8
-
25
-
-
73849135944
-
Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda
-
Mwesigwa, J., et al. 2010. Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda. Antimicrob. Agents Chemother. 54:52-59.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 52-59
-
-
Mwesigwa, J.1
-
26
-
-
0034950952
-
Desbutyl-benflumetol, a novel antimalarial compound: In vitro activity in fresh isolates of Plasmodium falciparum from Thailand
-
DOI 10.1128/AAC.45.7.2106-2109.2001
-
Noedl, H., T. Allmendinger, S. Prajakwong, G. Wernsdorfer, and W. H. Wernsdorfer. 2001. Desbutyl-benflumetol, a novel antimalarial compound: in vitro activity in fresh isolates of Plasmodium falciparum from Thailand. Antimicrob. Agents Chemother. 45:2106-2109. (Pubitemid 32591705)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.7
, pp. 2106-2109
-
-
Noedl, H.1
Allmendinger, T.2
Prajakwong, S.3
Wernsdorfer, G.4
Wernsdorfer, W.H.5
-
27
-
-
33646736568
-
Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria
-
Price, R. N., et al. 2006. Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria. Clin. Infect. Dis. 42:1570-1577.
-
(2006)
Clin. Infect. Dis.
, vol.42
, pp. 1570-1577
-
-
Price, R.N.1
-
28
-
-
57849106490
-
Interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum in vitro
-
Starzengruber, P., et al. 2008. Interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum in vitro. Wien. Klin. Wochenschr. 120:85-89.
-
(2008)
Wien. Klin. Wochenschr.
, vol.120
, pp. 85-89
-
-
Starzengruber, P.1
-
29
-
-
36049012223
-
Specific pharmacokinetic interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum
-
DOI 10.1007/s00508-007-0861-9, Vortrage der 40. Jahrestagung der Osterreichischen Gesellschaft fur Tropenmedizin und Parasitologie, Linz, 2.-4. November 2006
-
Starzengruber, P., et al. 2007. Specific pharmacokinetic interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum. Wien. Klin. Wochenschr. 119:60-66. (Pubitemid 350094907)
-
(2007)
Wiener Klinische Wochenschrift
, vol.119
, Issue.SUPPL. 3
, pp. 60-66
-
-
Starzengruber, P.1
Wernsdorfer, G.2
Parizek, M.3
Rojanawatsirivet, C.4
Kollaritsch, H.5
Wernsdorfer, W.H.6
-
30
-
-
70349119891
-
Population pharmacokinetics of lumefantrine in pregnant women treated with artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria
-
Tarning, J., et al. 2009. Population pharmacokinetics of lumefantrine in pregnant women treated with artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria. Antimicrob. Agents Chemother. 53:3837-3846.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 3837-3846
-
-
Tarning, J.1
-
31
-
-
0033067324
-
Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria
-
DOI 10.1016/S0924-8579(99)00063-1, PII S0924857999000631
-
van Agtmael, M. A., S. Cheng-Qi, J. X. Qing, R. Mull, and C. J. van Boxtel. 1999. Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria. Int. J. Antimicrob. Agents 12:151-158. (Pubitemid 29276919)
-
(1999)
International Journal of Antimicrobial Agents
, vol.12
, Issue.2
, pp. 151-158
-
-
Van Agtmael, M.A.1
Cheng-Qi, S.2
Qing, J.X.3
Mull, R.4
Van Boxtel, C.J.5
-
32
-
-
79952339074
-
Desbutyl-lumefantrine is a metabolite of lumefantrine with potent in vitro antimalarial activity that may influence artemether-lumefantrine treatment outcome
-
Wong, R. P. M., et al. 2011. Desbutyl-lumefantrine is a metabolite of lumefantrine with potent in vitro antimalarial activity that may influence artemether-lumefantrine treatment outcome. Antimicrob. Agents Chemother. 55:1194-1198.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 1194-1198
-
-
Wong, R.P.M.1
-
33
-
-
79952193925
-
-
World Health Organization. World Health Organization, Geneva, Switzerland
-
World Health Organization. 2010. World malaria report. World Health Organization, Geneva, Switzerland.
-
(2010)
World Malaria Report
-
-
-
34
-
-
0034068284
-
Severe falciparum malaria
-
World Health Organization, Communicable Diseases Cluster
-
World Health Organization, Communicable Diseases Cluster. 2000. Severe falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 94(Suppl. 1):S1-S90.
-
(2000)
Trans. R. Soc. Trop. Med. Hyg.
, vol.94
, Issue.SUPPL. 1
-
-
-
35
-
-
78650684954
-
Evaluations of Bayesian and maximum likelihood methods in PK models with below-quantification-limit data
-
Yang, S., and J. Roger. 2010. Evaluations of Bayesian and maximum likelihood methods in PK models with below-quantification-limit data. Pharm. Stat. 9:313-330.
-
(2010)
Pharm. Stat.
, vol.9
, pp. 313-330
-
-
Yang, S.1
Roger, J.2
|