Leishmania-host interactions: What has imaging taught us?

Cellular Microbiology

Volumn 13, Issue 11, 2011, Pages 1659-1667

  Beattie, Lynette ^a,b   Kaye, Paul M ^a,b  

^a UNIVERSITY OF HULL   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTOZOAL PROTEIN;

CELL PROLIFERATION; CONFOCAL MICROSCOPY; DISEASE COURSE; ELECTRON MICROSCOPY; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN; LEISHMANIA; LYSOSOME; MAMMAL; MICROSCOPY; MOLECULAR IMAGING; MONONUCLEAR PHAGOCYTE; NONHUMAN; PARASITE SURVIVAL; PARASITE TRANSMISSION; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROMASTIGOTE; PROTIST LIFE CYCLE STAGE; SHORT SURVEY; TRANSGENIC ORGANISM;

CYTOLOGICAL TECHNIQUES; HOST-PATHOGEN INTERACTIONS; IMAGE PROCESSING, COMPUTER-ASSISTED; LEISHMANIA; LEISHMANIASIS; MICROSCOPY; PARASITOLOGY; PATHOLOGY; WHOLE BODY IMAGING;

ANIMALIA; MAMMALIA;

EID: 80054123453     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2011.01658.x     Document Type: Short Survey

References (57)

1. Akiyama, H.J., and McQuillen, N.K. (1972) Interaction and transformation of Leishmania donovani within in vitro cultured cells. An electron microscopical study. Am J Trop Med Hyg 21: 873-879.
2. Akopyants, N.S., Kimblin, N., Secundino, N., Patrick, R., Peters, N., Lawyer, P., etal. (2009) Demonstration of genetic exchange during cyclical development of Leishmania in the sand fly vector. Science 324: 265-268.
3. Alexander, J. (1975) Effect of the antiphagocytic agent cytochalasin B on macrophage invasion by Leishmania mexicana promastigotes and Trypanosoma cruzi epimastigotes. J Protozool 22: 237-240.
4. Alexander, J., and Vickerman, K. (1975) Fusion of host cell secondary lysosomes with the parasitophorous vacuoles of Leishmania mexicana-infected macrophages. J Protozool 22: 502-508.
5. Amino, R., Giovannini, D., Thiberge, S., Gueirard, P., Boisson, B., Dubremetz, J.F., etal. (2008) Host cell traversal is important for progression of the malaria parasite through the dermis to the liver. Cell Host Microbe 3: 88-96.
6. Angarano, G., Maggi, P., Rollo, M.A., Larocca, A.M., Quarto, M., Scalone, A., and Gradoni, L. (1998) Diffuse necrotic hepatic lesions due to visceral leishmaniasis in AIDS. J Infect 36: 167-169.
7. Baer, K., Roosevelt, M., Clarkson, A.B., Jr, van Rooijen, N., Schnieder, T., and Frevert, U. (2007) Kupffer cells are obligatory for Plasmodium yoelii sporozoite infection of the liver. Cell Microbiol 9: 397-412.
8. Barak, E., Amin-Spector, S., Gerliak, E., Goyard, S., Holland, N., and Zilberstein, D. (2005) Differentiation of Leishmania donovani in host-free system: analysis of signal perception and response. Mol Biochem Parasitol 141: 99-108.
9. Beattie, L., Peltan, A., Maroof, A., Kirby, A., Brown, N., Coles, M., etal. (2010) Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells. PLoS Pathog 6: e1000805.
10. Beattie, L., Phillips, R., Brown, N., Owens, B.M., Chauhan, N., Dalton, J.E., and Kaye, P.M. (2011) Interferon regulatory factor 7 contributes to the control of Leishmania donovani in the mouse liver. Infect Immun 79: 1057-1066.
11. Bennett, C.L., Misslitz, A., Colledge, L., Aebischer, T., and Blackburn, C.C. (2001) Silent infection of bone marrow-derived dendritic cells by Leishmania mexicana amastigotes. Eur J Immunol 31: 876-883.
12. Bolhassani, A., Gholami, E., Zahedifard, F., Moradin, N., Parsi, P., Doustdari, F., etal. (2011) Leishmania major: protective capacity of DNA vaccine using amastin fused to HSV-1 VP22 and EGFP in BALB/c mice model. Exp Parasitol 128: 9-17.
13. Bukte, Y., Nazaroglu, H., Mete, A., and Yilmaz, F. (2004) Visceral leishmaniasis with multiple nodular lesions of the liver and spleen: CT and sonographic findings. Abdom Imaging 29: 82-84.
14. Castro, R., Scott, K., Jordan, T., Evans, B., Craig, J., Peters, E.L., and Swier, K. (2006) The ultrastructure of the parasitophorous vacuole formed by Leishmania major. J Parasitol 92: 1162-1170.
15. Chang, K.P., and Dwyer, D.M. (1976) Multiplication of a human parasite (Leishmania donovani) in phagolysosomes of hamster macrophages in vitro. Science 193: 678-680.
16. Collins, H.L., Schaible, U.E., Ernst, J.D., and Russell, D.G. (1997) Transfer of phagocytosed particles to the parasitophorous vacuole of Leishmania mexicana is a transient phenomenon preceding the acquisition of annexin I by the phagosome. J Cell Sci 110: 191-200.
17. Costa, A.A., Saldanha, A.C., Leite, B.M., Ramos, B., Junior, I.A., Noronha, A.L., etal. (2005) Imaging exams of bone lesions in patients with diffuse cutaneous leishmaniasis (DCL). Acta Trop 96: 9-15.
18. Courret, N., Frehel, C., Gouhier, N., Pouchelet, M., Prina, E., Roux, P., and Antoine, J.C. (2002) Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites. J Cell Sci 115: 2303-2316.
19. Dermine, J.F., Scianimanico, S., Prive, C., Descoteaux, A., and Desjardins, M. (2000) Leishmania promastigotes require lipophosphoglycan to actively modulate the fusion properties of phagosomes at an early step of phagocytosis. Cell Microbiol 2: 115-126.
20. Desjardins, M. (1995) Biogenesis of phagolysosomes: the 'kiss and run' hypothesis. Trends Cell Biol 5: 183-186.
21. Duclos, S., Diez, R., Garin, J., Papadopoulou, B., Descoteaux, A., Stenmark, H., and Desjardins, M. (2000) Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages. J Cell Sci 113: 3531-3541.
22. Filipe-Santos, O., Pescher, P., Breart, B., Lippuner, C., Aebischer, T., Glaichenhaus, N., etal. (2009) A dynamic map of antigen recognition by CD4 T cells at the site of Leishmania major infection. Cell Host Microbe 6: 23-33.
23. Forestier, C.L., Machu, C., Loussert, C., Pescher, P., and Spath, G.F. (2011) Imaging host cell-leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process. Cell Host Microbe 9: 319-330.
24. Holm, A., Tejle, K., Magnusson, K.E., Descoteaux, A., and Rasmusson, B. (2001) Leishmania donovani lipophosphoglycan causes periphagosomal actin accumulation: correlation with impaired translocation of PKCalpha and defective phagosome maturation. Cell Microbiol 3: 439-447.
25. de La Llave, E., Lecoeur, H., Besse, A., Milon, G., Prina, E., and Lang, T. (2011) A combined luciferase imaging and reverse transcription polymerase chain reaction assay for the study of Leishmania amastigote burden and correlated mouse tissue transcript fluctuations. Cell Microbiol 13: 81-91.
26. Lang, T., Hellio, R., Kaye, P.M., and Antoine, J.C. (1994) Leishmania donovani-infected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentation. J Cell Sci 107: 2137-2150.
27. Lang, T., Ave, P., Huerre, M., Milon, G., and Antoine, J.C. (2000) Macrophage subsets harbouring Leishmania donovani in spleens of infected BALB/c mice: localization and characterization. Cell Microbiol 2: 415-430.
28. Lang, T., Goyard, S., Lebastard, M., and Milon, G. (2005) Bioluminescent Leishmania expressing luciferase for rapid and high throughput screening of drugs acting on amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice. Cell Microbiol 7: 383-392.
29. Laufs, H., Muller, K., Fleischer, J., Reiling, N., Jahnke, N., Jensenius, J.C., etal. (2002) Intracellular survival of Leishmania major in neutrophil granulocytes after uptake in the absence of heat-labile serum factors. Infect Immun 70: 826-835.
30. Lecoeur, H., Llave, E., Osorio, Y.F.J., Goyard, S., Kiefer-Biasizzo, H., Balazuc, A.M., etal. (2010) Sorting of Leishmania-bearing dendritic cells reveals subtle parasite-induced modulation of host-cell gene expression. Microbes Infect 12: 46-54.
31. Lippuner, C., Paape, D., Paterou, A., Brand, J., Richardson, M., Smith, A.J., etal. (2009) Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice. FASEB J 23: 483-491.
32. McDonald, B., Pittman, K., Menezes, G.B., Hirota, S.A., Slaba, I., Waterhouse, C.C., etal. (2010) Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science 330: 362-366.
33. Mehta, S.R., Huang, R., Yang, M., Zhang, X.Q., Kolli, B., Chang, K.P., etal. (2008) Real-time in vivo green fluorescent protein imaging of a murine leishmaniasis model as a new tool for Leishmania vaccine and drug discovery. Clin Vaccine Immunol 15: 1764-1770.
34. Mollinedo, F., Janssen, H., de la Iglesia-Vicente, J., Villa-Pulgarin, J.A., and Calafat, J. (2010) Selective fusion of azurophilic granules with Leishmania-containing phagosomes in human neutrophils. J Biol Chem 285: 34528-34536.
35. Moody, S.F., Handman, E., McConville, M.J., and Bacic, A. (1993) The structure of Leishmania major amastigote lipophosphoglycan. J Biol Chem 268: 18457-18466.
36. Ndjamen, B., Kang, B.H., Hatsuzawa, K., and Kima, P.E. (2010) Leishmania parasitophorous vacuoles interact continuously with the host cell's endoplasmic reticulum; parasitophorous vacuoles are hybrid compartments. Cell Microbiol 12: 1480-1494.
37. Ng, L.G., Hsu, A., Mandell, M.A., Roediger, B., Hoeller, C., Mrass, P., etal. (2008) Migratory dermal dendritic cells act as rapid sensors of protozoan parasites. PLoS Pathog 4: e1000222.
38. Ng, L.G., Qin, J.S., Roediger, B., Wang, Y., Jain, R., Cavanagh, L.L., etal. (2011) Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events. J Invest Dermatoldoi: 10.1038/jid.2011.179.
39. Pearson, R.D., Romito, R., Symes, P.H., and Harcus, J.L. (1981) Interaction of Leishmania donovani promastigotes with human monocyte-derived macrophages: parasite entry, intracellular survival, and multiplication. Infect Immun 32: 1249-1253.
40. Peters, N.C., Egen, J.G., Secundino, N., Debrabant, A., Kimblin, N., Kamhawi, S., etal. (2008) In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies. Science 321: 970-974.
41. Phillips, R., Svensson, M., Aziz, N., Maroof, A., Brown, N., Beattie, L., etal. (2010) Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7. PLoS Pathog 6: e1000813.
42. Prina, E., Abdi, S.Z., Lebastard, M., Perret, E., Winter, N., and Antoine, J.C. (2004) Dendritic cells as host cells for the promastigote and amastigote stages of Leishmania amazonensis: the role of opsonins in parasite uptake and dendritic cell maturation. J Cell Sci 117: 315-325.
43. Real, F., Pouchelet, M., and Rabinovitch, M. (2008) Leishmania (L.) amazonensis: fusion between parasitophorous vacuoles in infected bone-marrow derived mouse macrophages. Exp Parasitol 119: 15-23.
44. Real, F., Mortara, R.A., and Rabinovitch, M. (2010) Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. PLoS Negl Trop Dis 4: e905.
45. Ritter, U., Mattner, J., Rocha, J.S., Bogdan, C., and Korner, H. (2004) The control of Leishmania (Leishmania) major by TNF in vivo is dependent on the parasite strain. Microbes Infect 6: 559-565.
46. Ritter, U., Frischknecht, F., and van Zandbergen, G. (2009) Are neutrophils important host cells for Leishmania parasites? Trends Parasitol 25: 505-510.
47. Rodriguez, N.E., Gaur, U., and Wilson, M.E. (2006) Role of caveolae in Leishmania chagasi phagocytosis and intracellular survival in macrophages. Cell Microbiol 8: 1106-1120.
48. Rowe, H.M., Lopes, L., Brown, N., Efklidou, S., Smallie, T., Karrar, S., etal. (2009) Expression of vFLIP in a lentiviral vaccine vector activates NF-{kappa}B, matures dendritic cells, and increases CD8+ T-cell responses. J Virol 83: 1555-1562.
49. Russell, D.G., Xu, S., and Chakraborty, P. (1992) Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages. J Cell Sci 103: 1193-1210.
50. Scianimanico, S., Desrosiers, M., Dermine, J.F., Meresse, S., Descoteaux, A., and Desjardins, M. (1999) Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes. Cell Microbiol 1: 19-32.
51. Stenger, S., and van Zandbergen, G. (2011) Measuring the killing of intracellular pathogens: leishmania. Curr Protoc Immunol Chapter 14, Unit14 23.
52. Tolson, D.L., Turco, S.J., and Pearson, T.W. (1990) Expression of a repeating phosphorylated disaccharide lipophosphoglycan epitope on the surface of macrophages infected with Leishmania donovani. Infect Immun 58: 3500-3507.
53. Vanderberg, J.P., and Frevert, U. (2004) Intravital microscopy demonstrating antibody-mediated immobilisation of Plasmodium berghei sporozoites injected into skin by mosquitoes. Int J Parasitol 34: 991-996.
54. Viglianesi, A., Di Mauro, D., and Petrillo, G. (2011) Multidetector computed tomography aspects of tracheal mucosal leishmaniasis localization. Jpn J Radiol 29: 59-62.
55. WHO (2010) Control of the Leishmaniases: report of a meeting of the WHO expert committee on the control of leishmaniases, Geneva, 22-26 March 2010. WHO Technical Report Series.
56. Yates, R.M., Hermetter, A., and Russell, D.G. (2005) The kinetics of phagosome maturation as a function of phagosome/lysosome fusion and acquisition of hydrolytic activity. Traffic 6: 413-420.
57. van Zandbergen, G., Klinger, M., Mueller, A., Dannenberg, S., Gebert, A., Solbach, W., and Laskay, T. (2004) Cutting edge: neutrophil granulocyte serves as a vector for Leishmania entry into macrophages. J Immunol 173: 6521-6525.