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Volumn 23, Issue 6, 2011, Pages 559-565

Unravelling the epigenomic dimension of breast cancers

Author keywords

breast cancer; DNA methylation; epigenetics; epigenomics

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA; DNA METHYLTRANSFERASE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PHOSPHOPROTEIN; PROTEIN BRCAX; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 80054113710     PISSN: 10408746     EISSN: 1531703X     Source Type: Journal    
DOI: 10.1097/CCO.0b013e32834bd481     Document Type: Review
Times cited : (23)

References (34)
  • 1
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127:2893-2917.
    • (2010) Int J Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3
  • 2
    • 77649267695 scopus 로고    scopus 로고
    • Dynamic changes in the human methylome during differentiation
    • Laurent L, Wong E, Li G, et al. Dynamic changes in the human methylome during differentiation. Genome Res 2010; 20:320-331.
    • (2010) Genome Res , vol.20 , pp. 320-331
    • Laurent, L.1    Wong, E.2    Li, G.3
  • 3
    • 70450217879 scopus 로고    scopus 로고
    • Human DNA methylomes at base resolution show widespread epigenomic differences
    • Lister R, Pelizzola M, Dowen RH, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009; 462: 315-322.
    • (2009) Nature , vol.462 , pp. 315-322
    • Lister, R.1    Pelizzola, M.2    Dowen, R.H.3
  • 6
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol 2010; 28:1057-1068.
    • (2010) Nat Biotechnol , vol.28 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 7
    • 79952111066 scopus 로고    scopus 로고
    • Chromatin remodeling in mammary gland differentiation and breast tumorigenesis
    • Huang TH, EstellerM. Chromatin remodeling in mammary gland differentiation and breast tumorigenesis. Cold Spring Harb Perspect Biol 2010; 2:a004515.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Huang, T.H.1    Esteller, M.2
  • 9
    • 61549112191 scopus 로고    scopus 로고
    • Epigenomics and breast cancer
    • Lo PK, Sukumar S. Epigenomics and breast cancer. Pharmacogenomics 2008; 9:1879-1902.
    • (2008) Pharmacogenomics , vol.9 , pp. 1879-1902
    • Lo, P.K.1    Sukumar, S.2
  • 10
    • 36549029229 scopus 로고    scopus 로고
    • Correlation between CpG methylation profiles and hormone receptor status in breast cancers
    • Feng W, Shen L, Wen S, et al. Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res 2007; 9:R57.
    • (2007) Breast Cancer Res , vol.9
    • Feng, W.1    Shen, L.2    Wen, S.3
  • 11
    • 55749101607 scopus 로고    scopus 로고
    • Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors
    • Sunami E, Shinozaki M, Sim MS, et al. Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors. Breast Cancer Res 2008; 10:R46.
    • (2008) Breast Cancer Res , vol.10
    • Sunami, E.1    Shinozaki, M.2    Sim, M.S.3
  • 13
    • 77957329892 scopus 로고    scopus 로고
    • Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake
    • Christensen BC, Kelsey KT, Zheng S, et al. Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet 2010; 6:e1001043.
    • (2010) PLoS Genet , vol.6
    • Christensen, B.C.1    Kelsey, K.T.2    Zheng, S.3
  • 14
    • 79954623906 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity
    • Hill VK, Ricketts C, Bieche I, et al. Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity. Cancer Res 2011; 71:2988-2999.
    • (2011) Cancer Res , vol.71 , pp. 2988-2999
    • Hill, V.K.1    Ricketts, C.2    Bieche, I.3
  • 15
    • 77958540564 scopus 로고    scopus 로고
    • Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
    • Holm K, Hegardt C, Staaf J, et al. Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns. Breast Cancer Res 2010; 12:R36.
    • (2010) Breast Cancer Res , vol.12
    • Holm, K.1    Hegardt, C.2    Staaf, J.3
  • 16
    • 80052428035 scopus 로고    scopus 로고
    • A methyl-deviator epigenotype of estrogen receptor-positive breast carcinoma is associated with malignant biology
    • Killian JK, Bilke S, Davis S, et al. A methyl-deviator epigenotype of estrogen receptor-positive breast carcinoma is associated with malignant biology. Am J Pathol 2011; 179:55-65.
    • (2011) Am J Pathol , vol.179 , pp. 55-65
    • Killian, J.K.1    Bilke, S.2    Davis, S.3
  • 17
    • 77957859971 scopus 로고    scopus 로고
    • Estrogen and progesterone receptor status affect genome-wide DNA methylation profile in breast cancer
    • Li L, Lee KM, Han W, et al. Estrogen and progesterone receptor status affect genome-wide DNA methylation profile in breast cancer. Hum Mol Genet 2010; 19:4273-4277.
    • (2010) Hum Mol Genet , vol.19 , pp. 4273-4277
    • Li, L.1    Lee, K.M.2    Han, W.3
  • 18
    • 78951491753 scopus 로고    scopus 로고
    • Methylation profiling with a panel of cancer related genes: Association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
    • Ronneberg JA, Fleischer T, Solvang HK, et al. Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer. Mol Oncol 2011; 5:61-76.
    • (2011) Mol Oncol , vol.5 , pp. 61-76
    • Ronneberg, J.A.1    Fleischer, T.2    Solvang, H.K.3
  • 19
    • 79952122331 scopus 로고    scopus 로고
    • Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing
    • Sun Z, Asmann YW, Kalari KR, et al. Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing. PLoS One 2011; 6:e17490.
    • (2011) PLoS One , vol.6
    • Sun, Z.1    Asmann, Y.W.2    Kalari, K.R.3
  • 20
    • 77649238322 scopus 로고    scopus 로고
    • DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status
    • Flanagan JM, Cocciardi S, Waddell N, et al. DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. Am J Hum Genet 2010; 86:420-433.
    • (2010) Am J Hum Genet , vol.86 , pp. 420-433
    • Flanagan, J.M.1    Cocciardi, S.2    Waddell, N.3
  • 21
    • 78650877915 scopus 로고    scopus 로고
    • DNA methylation epigenotypes in breast cancer molecular subtypes
    • Bediaga NG, Acha-Sagredo A, Guerra I, et al. DNA methylation epigenotypes in breast cancer molecular subtypes. Breast Cancer Res 2010; 12:R77.
    • (2010) Breast Cancer Res , vol.12
    • Bediaga, N.G.1    Acha-Sagredo, A.2    Guerra, I.3
  • 22
    • 78951487862 scopus 로고    scopus 로고
    • DNA methylation patterns in luminal breast cancers differ from nonluminal subtypes and can identify relapse risk independent of other clinical variables
    • Kamalakaran S, Varadan V, Giercksky Russnes HE, et al. DNA methylation patterns in luminal breast cancers differ from nonluminal subtypes and can identify relapse risk independent of other clinical variables. Mol Oncol 2011; 5:77-92.
    • (2011) Mol Oncol , vol.5 , pp. 77-92
    • Kamalakaran, S.1    Varadan, V.2    Giercksky Russnes, H.E.3
  • 26
    • 39649104991 scopus 로고    scopus 로고
    • DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
    • Roll JD, Rivenbark AG, Jones WD, Coleman WB. DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. Mol Cancer 2008; 7:15.
    • (2008) Mol Cancer , vol.7 , pp. 15
    • Roll, J.D.1    Rivenbark, A.G.2    Jones, W.D.3    Coleman, W.B.4
  • 27
    • 77958548605 scopus 로고    scopus 로고
    • Array-based DNA methylation profiling for breast cancer subtype discrimination
    • Van der Auwera I, Yu W, Suo L, et al. Array-based DNA methylation profiling for breast cancer subtype discrimination. PLoS One 2010; 5: e12616.
    • (2010) PLoS One , vol.5
    • Van Der Auwera, I.1    Yu, W.2    Suo, L.3
  • 28
    • 79953123510 scopus 로고    scopus 로고
    • Breast cancer methylomes establish an epigenomic foundation for metastasis
    • Fang F, Turcan S, Rimner A, et al. Breast cancer methylomes establish an epigenomic foundation for metastasis. Sci Transl Med 2011; 3:75ra25.
    • (2011) Sci Transl Med , vol.3
    • Fang, F.1    Turcan, S.2    Rimner, A.3
  • 29
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair geneMGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair geneMGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343:1350-1354.
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3
  • 30
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • Lim E, Vaillant F, Wu D, et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med 2009; 15:907-913.
    • (2009) Nat Med , vol.15 , pp. 907-913
    • Lim, E.1    Vaillant, F.2    Wu, D.3
  • 31
    • 52949122883 scopus 로고    scopus 로고
    • Cell type-specific DNA methylation patterns in the human breast
    • Bloushtain-Qimron N, Yao J, Snyder EL, et al. Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci USA 2008; 105:14076-14081.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14076-14081
    • Bloushtain-Qimron, N.1    Yao, J.2    Snyder, E.L.3
  • 32
    • 79952716583 scopus 로고    scopus 로고
    • Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
    • Sproul D, Nestor C, Culley J, et al. Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer. Proc Natl Acad Sci USA 2011; 108:4364-4369.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4364-4369
    • Sproul, D.1    Nestor, C.2    Culley, J.3
  • 33
    • 79958754527 scopus 로고    scopus 로고
    • Validation of a DNA methylation microarray for 450 000 CpG sites in the human genome
    • Sandoval J, Heyn HA, Moran S, et al. Validation of a DNA methylation microarray for 450 000 CpG sites in the human genome. Epigenetics 2011; 6:692-702.
    • (2011) Epigenetics , vol.6 , pp. 692-702
    • Sandoval, J.1    Heyn, H.A.2    Moran, S.3
  • 34
    • 82455202257 scopus 로고    scopus 로고
    • DNA methylation profiling reveals a predominant immune component in breast cancers
    • (in press)
    • Dedeurwaerder S, Desmedt C, Calonne E, et al. DNA methylation profiling reveals a predominant immune component in breast cancers. EMBO Mol Med (in press).
    • EMBO Mol Med
    • Dedeurwaerder, S.1    Desmedt, C.2    Calonne, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.