메뉴 건너뛰기




Volumn 52, Issue 11, 2011, Pages 1965-1973

Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters

Author keywords

Cholesterol efflux; Cholesteryl ester transfer protein; High density lipoprotein; Low density lipoprotein

Indexed keywords

ANACETRAPIB; BILE ACID; CHOLESTEROL; CHOLESTEROL ESTER; CHOLESTEROL ESTER TRANSFER PROTEIN; CHOLIC ACID; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRITIUM;

EID: 80054094687     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M016410     Document Type: Article
Times cited : (74)

References (41)
  • 1
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease. The Framingham study
    • Gordon, T., W. P. Castelli, M. C. Hjortland, W. B. Kannel, and T. R. Dawber . 1977. High-density lipoprotein as a protective factor against coronary heart-disease-Framingham Study. Am. J. Med. 62 : 707-714. (Pubitemid 8110784)
    • (1977) American Journal of Medicine , vol.62 , Issue.5 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3
  • 2
    • 0017614773 scopus 로고
    • Tromso Heart-Study-high-density lipoprotein and coronary heartdisease - Prospective case-control study
    • Miller, N. E., D. S. Thelle, O. H. Forde, and O. D. Mjos . 1977. Tromso Heart-Study-high-density lipoprotein and coronary heartdisease - prospective case-control study. Lancet . 1: 965-968.
    • (1977) Lancet , vol.1 , pp. 965-968
    • Miller, N.E.1    Thelle, D.S.2    Forde, O.H.3    Mjos, O.D.4
  • 3
    • 0018860747 scopus 로고
    • Alpha lipoprotein (HDL) cholesterol in the serum and the risk of coronary heart disease and death
    • Keys, A. 1980. Alpha-lipoprotein (Hdl) cholesterol in the serum and the risk of coronary heart-disease and death. Lancet . 2 : 603-606. (Pubitemid 10056646)
    • (1980) Lancet , vol.2 , Issue.8195 , pp. 603-606
    • Keys, A.1
  • 4
    • 80054094256 scopus 로고
    • A major gene for low-levels of high-density lipoprotein cholesterol-the Collaborative Lipid Research Clinics Family Study
    • Namboodiri, K. K., K. D. Bucher, E. B. Kaplan, P. M. Laskarzewski, C. J. Glueck, and B. M. Rifkind . 1985. A major gene for low-levels of high-density lipoprotein cholesterol-the Collaborative Lipid Research Clinics Family Study. Clin. Res. 33: A890.
    • (1985) Clin. Res. , vol.33
    • Namboodiri, K.K.1    Bucher, K.D.2    Kaplan, E.B.3    Laskarzewski, P.M.4    Glueck, C.J.5    Rifkind, B.M.6
  • 5
    • 0025014653 scopus 로고
    • High-density lipoprotein cholesterol as a predictor of cardiovascular-disease mortality in men and women-the follow-up-study of the Lipid Research Clinics Prevalence Study
    • Jacobs, D. R., I. L. Mebane, S. I. Bangdiwala, M. H. Criqui, and H. A. Tyroler. 1990. High-density lipoprotein cholesterol as a predictor of cardiovascular-disease mortality in men and women-the follow-up-study of the Lipid Research Clinics Prevalence Study. Am. J. Epidemiol. 131: 32-47.
    • (1990) Am. J. Epidemiol. , vol.131 , pp. 32-47
    • Jacobs, D.R.1    Mebane, I.L.2    Bangdiwala, S.I.3    Criqui, M.H.4    Tyroler, H.A.5
  • 7
    • 33750477286 scopus 로고    scopus 로고
    • Efficacy and Safety of Torcetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor, in Individuals With Below-Average High-Density Lipoprotein Cholesterol Levels
    • DOI 10.1016/j.jacc.2006.06.067, PII S0735109706019917
    • Davidson, M. H., J. M. McKenney, C. L. Shear, and J. H. Revkin. 2006. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels. J. Am. Coll. Cardiol. 48 : 1774-1781. (Pubitemid 44648633)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.9 , pp. 1774-1781
    • Davidson, M.H.1    McKenney, J.M.2    Shear, C.L.3    Revkin, J.H.4
  • 8
    • 33750447972 scopus 로고    scopus 로고
    • Efficacy and Safety of Torcetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor, in Individuals With Below-Average High-Density Lipoprotein Cholesterol Levels on a Background of Atorvastatin
    • DOI 10.1016/j.jacc.2006.06.066, PII S0735109706019905
    • McKenney, J. M., M. H. Davidson, C. L. Shear, and J. H. Revkin. 2006. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average highdensity lipoproteín cholesterol levels on a background of atorvastatin. J. Am. Coll. Cardiol. 48: 1782-1790. (Pubitemid 44648632)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.9 , pp. 1782-1790
    • McKenney, J.M.1    Davidson, M.H.2    Shear, C.L.3    Revkin, J.H.4
  • 11
    • 61349154804 scopus 로고    scopus 로고
    • Mechanistic studies of blood pressure in rats treated with a series of cholesteryl ester transfer protein inhibitors
    • DePasquale, M., G. Cadelina, D. Knight, W. Loging, S. Winter, E. Blasi, D. Perry, and J. Keiser . 2009. Mechanistic studies of blood pressure in rats treated with a series of cholesteryl ester transfer protein inhibitors. Drug Dev. Res. 70: 35-48.
    • (2009) Drug Dev. Res. , vol.70 , pp. 35-48
    • DePasquale, M.1    Cadelina, G.2    Knight, D.3    Loging, W.4    Winter, S.5    Blasi, E.6    Perry, D.7    Keiser, J.8
  • 12
    • 66449084532 scopus 로고    scopus 로고
    • Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition
    • Hu, X., J. D. Dietz, C. S. Xia, D. R. Knight, W. T. Loging, A. H. Smith, H. D. Yuan, D. A. Perry, and J. Keiser . 2009. Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition. Endocrinology . 150: 2211-2219.
    • (2009) Endocrinology , vol.150 , pp. 2211-2219
    • Hu, X.1    Dietz, J.D.2    Xia, C.S.3    Knight, D.R.4    Loging, W.T.5    Smith, A.H.6    Yuan, H.D.7    Perry, D.A.8    Keiser, J.9
  • 14
    • 58649091088 scopus 로고    scopus 로고
    • Effi cacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients
    • Bloomfield, D., G. L. Carlson, A. Sapre, D. Tribble, J. M. McKenney, W. T. Littlejohn 3rd, C. M. Sisk, Y. Mitchel, and R. C. Pasternak. 2009. Effi cacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients. Am. Heart J. 157: 352-360.
    • (2009) Am. Heart J. , vol.157 , pp. 352-360
    • Bloomfield, D.1    Carlson, G.L.2    Sapre, A.3    Tribble, D.4    McKenney, J.M.5    Littlejohn III, W.T.6    Sisk, C.M.7    Mitchel, Y.8    Pasternak, R.C.9
  • 16
    • 66349086459 scopus 로고    scopus 로고
    • The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis
    • Rader, D. J., E. T. Alexander, G. L. Weibel, J. Billheimer, and G. H. Rothblat . 2009. The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis. J. Lipid Res. 50 : S189-S194.
    • (2009) J. Lipid Res. , vol.50
    • Rader, D.J.1    Alexander, E.T.2    Weibel, G.L.3    Billheimer, J.4    Rothblat, G.H.5
  • 17
    • 77649102918 scopus 로고    scopus 로고
    • The use of dyslipidemic hamsters to evaluate druginduced alterations in reverse cholesterol transport
    • Briand, F. 2010. The use of dyslipidemic hamsters to evaluate druginduced alterations in reverse cholesterol transport. Curr. Opin. Investig. Drugs . 11: 289-297.
    • (2010) Curr. Opin. Investig. Drugs , vol.11 , pp. 289-297
    • Briand, F.1
  • 18
    • 0041662117 scopus 로고    scopus 로고
    • Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo
    • DOI 10.1161/01.CIR.0000086981.09834.E0
    • Zhang, Y., I. Zanotti, M. P. Reilly, J. M. Glick, G. H. Rothblat, and D. J. Rader . 2003. Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation . 108: 661-663. (Pubitemid 36999247)
    • (2003) Circulation , vol.108 , Issue.6 , pp. 661-663
    • Zhang, Y.1    Zanotti, I.2    Reilly, M.P.3    Glick, J.M.4    Rothblat, G.H.5    Rader, D.J.6
  • 19
    • 33644865172 scopus 로고    scopus 로고
    • Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
    • DOI 10.1161/CIRCULATIONAHA.105.560177, PII 0000301720060103000015
    • Naik, S. U., X. Wang, J. S. Da Silva, M. Jaye, C. H. Macphee, M. P. Reilly, J. T. Billheimer, G. H. Rothblat, and D. J. Rader. 2006. Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo. Circulation . 113: 90-97. (Pubitemid 43958493)
    • (2006) Circulation , vol.113 , Issue.1 , pp. 90-97
    • Naik, S.U.1    Wang, X.2    Da Silva, J.S.3    Jaye, M.4    Macphee, C.H.5    Reilly, M.P.6    Billheimer, J.T.7    Rothblat, G.H.8    Rader, D.J.9
  • 20
    • 26444435788 scopus 로고    scopus 로고
    • Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo
    • DOI 10.1172/JCI25327
    • Zhang, Y., J. R. Da Silva, M. Reilly, J. T. Billheimer, G. H. Rothblat, and D. J. Rader . 2005. Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. J. Clin. Invest. 115: 2870-2874. (Pubitemid 41434414)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2870-2874
    • Zhang, Y.1    Da Silva, J.R.2    Reiliy, M.3    Billheimer, J.T.4    Rothblat, G.H.5    Rader, D.J.6
  • 21
    • 26844431924 scopus 로고    scopus 로고
    • Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation
    • DOI 10.1161/01.RES.0000185320.82962.F7
    • Moore, R. E., M. Navab, J. S. Millar, F. Zimetti, S. Hama, G. H. Rothblat, and D. J. Rader . 2005. Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased infl ammation. Circ. Res. 97: 763-771. (Pubitemid 41447126)
    • (2005) Circulation Research , vol.97 , Issue.8 , pp. 763-771
    • Moore, R.E.1    Navab, M.2    Millar, J.S.3    Zimetti, F.4    Hama, S.5    Rothblat, G.H.6    Rader, D.J.7
  • 22
    • 77950605567 scopus 로고    scopus 로고
    • Liver X receptor activation promotes macrophage-to-feces reverse cholesterol transport in a dyslipidemic hamster model
    • Briand, F., M. Treguier, A. Andre, D. Grillot, M. Issandou, K. Ouguerram, and T. Sulpice . 2010. Liver X receptor activation promotes macrophage-to-feces reverse cholesterol transport in a dyslipidemic hamster model. J. Lipid Res. 51: 763-770.
    • (2010) J. Lipid Res. , vol.51 , pp. 763-770
    • Briand, F.1    Treguier, M.2    Andre, A.3    Grillot, D.4    Issandou, M.5    Ouguerram, K.6    Sulpice, T.7
  • 25
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purifi cation
    • Bligh, E. G., and W. J. Dyer . 1959. A rapid method of total lipid extraction and purifi cation. Can. J. Biochem. Physiol. 37: 911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 28
    • 33745132444 scopus 로고    scopus 로고
    • Macrophage reverse cholesterol transport: Key to the regression of atherosclerosis?
    • DOI 10.1161/CIRCULATIONAHA.104.475715, PII 0000301720060530000014
    • Cuchel, M., and D. J. Rader . 2006. Macrophage reverse cholesterol transport: key to the regression of atherosclerosis? Circulation . 113 : 2548-2555. (Pubitemid 43948034)
    • (2006) Circulation , vol.113 , Issue.21 , pp. 2548-2555
    • Cuchel, M.1    Rader, D.J.2
  • 29
    • 39749120838 scopus 로고    scopus 로고
    • The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport
    • DOI 10.1093/cvr/cvm087
    • Tchoua, U., W. D'Souza, N. Mukhamedova, D. Blum, E. Niesor, J. Mizrahi, C. Maugeais, and D. Sviridov . 2008. The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport. Cardiovasc. Res. 77: 732-739. (Pubitemid 351301865)
    • (2008) Cardiovascular Research , vol.77 , Issue.4 , pp. 732-739
    • Tchoua, U.1    D'Souza, W.2    Mukhamedova, N.3    Blum, D.4    Niesor, E.5    Mizrahi, J.6    Maugeais, C.7    Sviridov, D.8
  • 30
    • 78650054881 scopus 로고    scopus 로고
    • Modulating cholesteryl ester transfer protein activity maintains effi cient pre-β-HDL formation and increases reverse cholesterol transport
    • Niesor, E. J., C. Magg, N. Ogawa, H. Okamoto, E. von der Mark, H. Matile, G. Schmid, R. G. Clerc, E. Chaput, D. Blum-Kaelin, et al. 2010. Modulating cholesteryl ester transfer protein activity maintains effi cient pre-β-HDL formation and increases reverse cholesterol transport. J. Lipid Res. 51: 3443-3454.
    • (2010) J. Lipid Res. , vol.51 , pp. 3443-3454
    • Niesor, E.J.1    Magg, C.2    Ogawa, N.3    Okamoto, H.4    Von Der Mark, E.5    Matile, H.6    Schmid, G.7    Clerc, R.G.8    Chaput, E.9    Blum-Kaelin, D.10
  • 31
    • 0025878994 scopus 로고
    • Comparative specifi city of plasma lecithin:cholesterol acyltransferase from ten animal species
    • Grove, D., and Pownall, H. J . 1991. Comparative specifi city of plasma lecithin:cholesterol acyltransferase from ten animal species. Lipids. 26: 416-420.
    • (1991) Lipids , vol.26 , pp. 416-420
    • Grove, D.1    Pownall, H.J.2
  • 32
    • 0029080806 scopus 로고
    • Specifi city of lecithin:cholesterol acyltransferase and atherogenic risk: Comparative studies on the plasma composition and in vitro synthesis of cholesteryl esters in 14 vertebrate species
    • Liu, M., J. D. Bagdade, and P. V. Subbaiah . 1995. Specifi city of lecithin:cholesterol acyltransferase and atherogenic risk: comparative studies on the plasma composition and in vitro synthesis of cholesteryl esters in 14 vertebrate species. Lipid Res. 36: 1813-1824.
    • (1995) Lipid Res. , vol.36 , pp. 1813-1824
    • Liu, M.1    Bagdade, J.D.2    Subbaiah, P.V.3
  • 33
    • 33646409606 scopus 로고    scopus 로고
    • HDL from CETP-defi cient subjects shows enhanced ability to promote cholesterol effl ux from macrophages in an apoE- And ABCG1- dependent pathway
    • Matsuura, F., N. Wang, W. Chen, X. C. Jiang, and A. R. Tall. 2006. HDL from CETP-defi cient subjects shows enhanced ability to promote cholesterol effl ux from macrophages in an apoE- and ABCG1- dependent pathway. J. Clin. Invest. 116: 1435-1442.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1435-1442
    • Matsuura, F.1    Wang, N.2    Chen, W.3    Jiang, X.C.4    Tall, A.R.5
  • 36
    • 0028047940 scopus 로고
    • Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: Effects on HDL subspecies, quantity, and apolipoprotein distribution
    • Evans, G. F., W. R. Bensch, L. D. Apelgren, D. Bailey, R. F. Kauffman, T. F. Bumol, and S. H. Zuckerman . 1994. Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: effects on HDL subspecies, quantity, and apolipoprotein distribution. J. Lipid Res. 35: 1634-1645. (Pubitemid 24291224)
    • (1994) Journal of Lipid Research , vol.35 , Issue.9 , pp. 1634-1645
    • Evans, G.F.1    Bensch, W.R.2    Apelgren, L.D.3    Bailey, D.4    Kauffman, R.F.5    Bumol, T.F.6    Zuckerman, S.H.7
  • 37
    • 0034991315 scopus 로고    scopus 로고
    • Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in obese hyperinsulinemic hamsters
    • van Heek, M., T. M. Austin, C. Farley, J. A. Cook, G. G. Tetzloff, and H. R. Davis . 2001. Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in obese hyperinsulinemic hamsters. Diabetes . 50: 1330-1335. (Pubitemid 32500165)
    • (2001) Diabetes , vol.50 , Issue.6 , pp. 1330-1335
    • Van Heek, M.1    Austin, T.M.2    Farley, C.3    Cook, J.A.4    Tetzloff, G.G.5    Davis, H.R.6
  • 38
    • 70349563838 scopus 로고    scopus 로고
    • Both the peroxisome proliferator-activated receptor (PPAR) delta agonist GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal re-absorption of HDL-derived cholesterol
    • Briand, F., S. U. Naik, I. Fuki, J. S. Millar, C. Macphee, M. Walker, J. Billheimer, G. Rothblat, and D. J. Rader . 2009. Both the peroxisome proliferator-activated receptor (PPAR) delta agonist GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal re-absorption of HDL-derived cholesterol. Clin. Transl. Sci. 2: 127-133.
    • (2009) Clin. Transl. Sci. , vol.2 , pp. 127-133
    • Briand, F.1    Naik, S.U.2    Fuki, I.3    Millar, J.S.4    Macphee, C.5    Walker, M.6    Billheimer, J.7    Rothblat, G.8    Rader, D.J.9
  • 39
    • 0029079691 scopus 로고
    • Effects of stigmastanyl-phosphocholine (Ro 16- 6532) and lovastatin on lipid and lipoprotein levels and lipoprotein metabolism in the hamster on different diets
    • Himber, J., B. Missano, M. Rudling, U. Hennes, and H. J. Kempen . 1995. Effects of stigmastanyl-phosphocholine (Ro 16- 6532) and lovastatin on lipid and lipoprotein levels and lipoprotein metabolism in the hamster on different diets. J. Lipid Res. 36 : 1567-1585.
    • (1995) J. Lipid Res. , vol.36 , pp. 1567-1585
    • Himber, J.1    Missano, B.2    Rudling, M.3    Hennes, U.4    Kempen, H.J.5
  • 40
    • 0036213753 scopus 로고    scopus 로고
    • Experimental model of escape phenomenon in hamsters and the effectiveness of YM-53601 in the model
    • Ugawa, T., H. Kakuta, H. Moritani, and H. Shikama . 2002. Experimental model of escape phenomenon in hamsters and the effectiveness of YM-53601 in the model. Br. J. Pharmacol. 135: 1572-1578. (Pubitemid 34270930)
    • (2002) British Journal of Pharmacology , vol.135 , Issue.6 , pp. 1572-1578
    • Ugawa, T.1    Kakuta, H.2    Moritani, H.3    Shikama, H.4
  • 41
    • 77952684555 scopus 로고    scopus 로고
    • Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: Mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters
    • Dong, B., M. Wu, H. Li, F. B. Kraemer, K. Adeli, N. G. Seidah, S. W. Park, and J. Liu . 2010. Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. J. Lipid Res. 51: 1486-1495.
    • (2010) J. Lipid Res. , vol.51 , pp. 1486-1495
    • Dong, B.1    Wu, M.2    Li, H.3    Kraemer, F.B.4    Adeli, K.5    Seidah, N.G.6    Park, S.W.7    Liu, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.