Infectious delivery and long-term persistence of transgene expression in the brain by a 135-kb iBAC-FXN genomic DNA expression vector

Gene Therapy

Volumn 18, Issue 10, 2011, Pages 1015-1019

  Gimenez Cassina, A ^a   Wade Martins, R ^b   Gomez Sebastian, S ^b   Corona, J C ^a   Lim, F ^a   Diaz Nido, J ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Friedreich's ataxia; herpesvirus; HSV 1 amplicon vector; infectious BAC vector; long term transgene expression

Indexed keywords

BETA GALACTOSIDASE; GREEN FLUORESCENT PROTEIN; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CEREBELLUM; CONTROLLED STUDY; DNA VECTOR; EMBRYO; ESCHERICHIA COLI; FEMALE; FRIEDREICH ATAXIA; FXN GENE; GENE EXPRESSION; GENE LOCUS; GENE TARGETING; GENE THERAPY; GENOMICS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CELLS, CULTURED; CEREBELLUM; CHROMOSOMES, ARTIFICIAL, BACTERIAL; DNA PRIMERS; ESCHERICHIA COLI; FRIEDREICH ATAXIA; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HERPESVIRUS 1, HUMAN; IMMUNOHISTOCHEMISTRY; IRON-BINDING PROTEINS; LAC OPERON; MICE; MICROSCOPY, FLUORESCENCE; TRANSGENES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HERPESVIRIDAE; HUMAN HERPESVIRUS 1;

EID: 80054087842     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.45     Document Type: Article

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