A potent inhibitor of sik2, 3, 3′, 7-trihydroxy-4′-methoxyflavon (4′-o-methylfisetin), promotes melanogenesis in b16f10 melanoma cells

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Kumagai, Ayako ^a,b   Horike, Nanao ^a,b   Satoh, Yudai ^a   Uebi, Tatsuya ^b   Sasaki, Tsutomu ^c   Itoh, Yumi ^b   Hirata, Yoshiyuki ^a   Uchio Yamada, Kozue ^b   Kitagawa, Kazuo ^c   Uesato, Shinichi ^a   Kawahara, Hidehisa ^a   Takemori, Hiroshi ^b   Nagaoka, Yasuo ^a  

^a KANSAI UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3,3',7 TRIHYDROXY 4' METHOXYFLAVON; 4' O METHYLFISETIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN SPECIFIC COACTIVATOR 1; DIOSMETIN; ENZYME INHIBITOR; FISETIN; MONOMETHYLFISETIN; SALT INDUCIBLE KINASE 2 INHIBITOR; UNCLASSIFIED DRUG; 3,3',7-TRIHYDROXY-4'-METHOXYFLAVON; CYCLIC AMP; EUMELANIN; FLAVONOID; MELANIN; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; SALT INDUCIBLE KINASE 2, MOUSE; SALT-INDUCIBLE KINASE-2, MOUSE; TORC1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG ACTIVITY; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; EUMELANOGENESIS; FECES ANALYSIS; FEEDING BEHAVIOR; GENE OVEREXPRESSION; GENE TRANSLOCATION; HAIR COLOR; IN VITRO STUDY; IN VIVO STUDY; MELANOGENESIS; MELANOMA CELL; METABOLITE; MOUSE; NONHUMAN; PHEOMELANOGENESIS; PROTEIN ANALYSIS; ANIMAL; BIOSYNTHESIS; CELL STRAIN HEK293; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; EXPERIMENTAL MELANOMA; HUMAN; METABOLISM; PATHOLOGY;

MUS;

ANIMALS; CYCLIC AMP; FLAVONOIDS; HEK293 CELLS; HUMANS; MELANINS; MELANOMA, EXPERIMENTAL; MICE; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS;

EID: 80054085420     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026148     Document Type: Article

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