메뉴 건너뛰기




Volumn 119, Issue 3, 2011, Pages 594-603

Diabetic neuropathy enhances voltage-activated Ca 2+ channel activity and its control by M 4 muscarinic receptors in primary sensory neurons

Author keywords

acetylcholine; analgesia; muscarinic receptors; neuropathic pain

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL T TYPE; HIGH VOLTAGE ACTIVATED CALCIUM CHANNEL; HIMBACINE; MESSENGER RNA; MUSCARINIC M2 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; MUSCARINIC TOXIN 3; OXOTREMORINE; UNCLASSIFIED DRUG;

EID: 80054074898     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07456.x     Document Type: Article
Times cited : (47)

References (53)
  • 1
    • 0347224274 scopus 로고    scopus 로고
    • Cell-Specific Alternative Splicing Increases Calcium Channel Current Density in the Pain Pathway
    • DOI 10.1016/S0896-6273(03)00801-8
    • Bell T. J., Thaler C., Castiglioni A. J., Helton T. D., and, Lipscombe D., (2004) Cell-specific alternative splicing increases calcium channel current density in the pain pathway. Neuron 41, 127-138. (Pubitemid 38068440)
    • (2004) Neuron , vol.41 , Issue.1 , pp. 127-138
    • Bell, T.J.1    Thaler, C.2    Castiglioni, A.J.3    Helton, T.D.4    Lipscombe, D.5
  • 4
    • 70350127316 scopus 로고    scopus 로고
    • Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats
    • Cai Y. Q., Chen S. R., Han H. D., Sood A. K., Lopez-Berestein G., and, Pan H. L., (2009) Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats. J. Neurochem. 111, 1000-1010.
    • (2009) J. Neurochem. , vol.111 , pp. 1000-1010
    • Cai, Y.Q.1    Chen, S.R.2    Han, H.D.3    Sood, A.K.4    Lopez-Berestein, G.5    Pan, H.L.6
  • 5
    • 77955143610 scopus 로고    scopus 로고
    • Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: Role of brain-derived neurotrophic factor
    • Cao X. H., Byun H. S., Chen S. R., Cai Y. Q., and, Pan H. L., (2010) Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor. J. Neurochem. 114, 1460-1475.
    • (2010) J. Neurochem. , vol.114 , pp. 1460-1475
    • Cao, X.H.1    Byun, H.S.2    Chen, S.R.3    Cai, Y.Q.4    Pan, H.L.5
  • 6
    • 0021169994 scopus 로고
    • A low voltage-activated, fully inactivating Ca channel in vertebrate sensory neurons
    • Carbone E., and, Lux H. D., (1984) A low voltage-activated, fully inactivating Ca channel in vertebrate sensory neurones. Nature 310, 501-502. (Pubitemid 14052412)
    • (1984) Nature , vol.310 , Issue.5977 , pp. 501-502
    • Carbone, E.1    Lux, H.D.2
  • 7
    • 0027208248 scopus 로고
    • Muscarinic receptors - Characterization, coupling and function
    • Caulfield M. P., (1993) Muscarinic receptors-characterization, coupling and function. Pharmacol. Ther. 58, 319-379. (Pubitemid 23273186)
    • (1993) Pharmacology and Therapeutics , vol.58 , Issue.3 , pp. 319-379
    • Caulfield, M.P.1
  • 8
    • 0036554716 scopus 로고    scopus 로고
    • 1l) to neuronal excitability
    • DOI 10.1113/jphysiol.2001.013269
    • Chemin J., Monteil A., Perez-Reyes E., Bourinet E., Nargeot J., and, Lory P., (2002) Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability. J. Physiol. 540, 3-14. (Pubitemid 35174982)
    • (2002) Journal of Physiology , vol.540 , Issue.1 , pp. 3-14
    • Chemin, J.1    Monteil, A.2    Perez-Reyes, E.3    Bourinet, E.4    Nargeot, J.5    Lory, P.6
  • 9
    • 0036088744 scopus 로고    scopus 로고
    • Hypersensitivity of spinothalamic tract neurons associated with diabetic neuropathic pain in rats
    • Chen S. R., and, Pan H. L., (2002) Hypersensitivity of spinothalamic tract neurons associated with diabetic neuropathic pain in rats. J. Neurophysiol. 87, 2726-2733.
    • (2002) J. Neurophysiol. , vol.87 , pp. 2726-2733
    • Chen, S.R.1    Pan, H.L.2
  • 10
    • 0142241283 scopus 로고    scopus 로고
    • Up-regulation of spinal muscarinic receptors and increased antinociceptive effect of intrathecal muscarine in diabetic rats
    • Chen S. R., and, Pan H. L., (2003) Up-regulation of spinal muscarinic receptors and increased antinociceptive effect of intrathecal muscarine in diabetic rats. J. Pharmacol. Exp. Ther. 307, 676-681.
    • (2003) J. Pharmacol. Exp. Ther. , vol.307 , pp. 676-681
    • Chen, S.R.1    Pan, H.L.2
  • 11
    • 33645749366 scopus 로고    scopus 로고
    • Blocking mu opioid receptors in the spinal cord prevents the analgesic action by subsequent systemic opioids
    • Chen S. R., and, Pan H. L., (2006) Blocking mu opioid receptors in the spinal cord prevents the analgesic action by subsequent systemic opioids. Brain Res. 1081, 119-125.
    • (2006) Brain Res. , vol.1081 , pp. 119-125
    • Chen, S.R.1    Pan, H.L.2
  • 12
    • 0034791765 scopus 로고    scopus 로고
    • Antiallodynic effect of intrathecal neostigmine is mediated by spinal nitric oxide in a rat model of diabetic neuropathic pain
    • Chen S. R., Khan G. M., and, Pan H. L., (2001) Antiallodynic effect of intrathecal neostigmine is mediated by spinal nitric oxide in a rat model of diabetic neuropathic pain. Anesthesiology 95, 1007-1012. (Pubitemid 32939128)
    • (2001) Anesthesiology , vol.95 , Issue.4 , pp. 1007-1012
    • Chen, S.-R.1    Khan, G.M.2    Pan, H.-L.3
  • 13
    • 18044365417 scopus 로고    scopus 로고
    • 4 receptor subtypes in the spinal cord studied with muscarinic acetylcholine receptor knockout mice
    • DOI 10.1124/jpet.104.082537
    • Chen S. R., Wess J., and, Pan H. L., (2005) Functional activity of the M2 and M4 receptor subtypes in the spinal cord studied with muscarinic acetylcholine receptor knockout mice. J. Pharmacol. Exp. Ther. 313, 765-770. (Pubitemid 40604177)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.313 , Issue.2 , pp. 765-770
    • Chen, S.-R.1    Wess, J.2    Pan, H.-L.3
  • 14
    • 78650396085 scopus 로고    scopus 로고
    • Dynamic control of glutamatergic synaptic input in the spinal cord by muscarinic receptor subtypes defined using knockout mice
    • Chen S. R., Chen H., Yuan W. X., Wess J., and, Pan H. L., (2010) Dynamic control of glutamatergic synaptic input in the spinal cord by muscarinic receptor subtypes defined using knockout mice. J. Biol. Chem. 285, 40427-40437.
    • (2010) J. Biol. Chem. , vol.285 , pp. 40427-40437
    • Chen, S.R.1    Chen, H.2    Yuan, W.X.3    Wess, J.4    Pan, H.L.5
  • 15
    • 0029069447 scopus 로고
    • Prevention and treatment of the complications of diabetes mellitus
    • Clark C. M., Jr, and, Lee D. A., (1995) Prevention and treatment of the complications of diabetes mellitus. N. Engl. J. Med. 332, 1210-1217.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1210-1217
    • Clark, Jr.C.M.1    Lee, D.A.2
  • 16
    • 0027286569 scopus 로고
    • Streptozocin-induced diabetic rats: Behavioural evidence for a model of chronic pain
    • DOI 10.1016/0304-3959(93)90059-X
    • Courteix C., Eschalier A., and, Lavarenne J., (1993) Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain. Pain 53, 81-88. (Pubitemid 23137271)
    • (1993) Pain , vol.53 , Issue.1 , pp. 81-88
    • Courteix, C.1    Eschalier, A.2    Lavarenne, J.3
  • 20
    • 0029086064 scopus 로고
    • Voltage-dependent calcium currents are enhanced in dorsal root ganglion neurones from the Bio Bred/Worchester diabetic rat
    • Hall K. E., Sima A. A., and, Wiley J. W., (1995) Voltage-dependent calcium currents are enhanced in dorsal root ganglion neurones from the Bio Bred/Worchester diabetic rat. J. Physiol. 486, 313-322.
    • (1995) J. Physiol. , vol.486 , pp. 313-322
    • Hall, K.E.1    Sima, A.A.2    Wiley, J.W.3
  • 21
    • 33646354887 scopus 로고    scopus 로고
    • Inhibitory M2 muscarinic receptors are upregulated in both axotomized and intact small diameter dorsal root ganglion cells after peripheral nerve injury
    • DOI 10.1016/j.neuroscience.2006.02.013, PII S0306452206001874
    • Hayashida K. I., Bynum T., Vincler M., and, Eisenach J. C., (2006) Inhibitory M2 muscarinic receptors are upregulated in both axotomized and intact small diameter dorsal root ganglion cells after peripheral nerve injury. Neuroscience 140, 259-268. (Pubitemid 43668444)
    • (2006) Neuroscience , vol.140 , Issue.1 , pp. 259-268
    • Hayashida, K.-I.1    Bynum, T.2    Vincler, M.3    Eisenach, J.C.4
  • 23
    • 12844286900 scopus 로고    scopus 로고
    • Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1
    • DOI 10.1074/jbc.M408500200
    • Hong S., and, Wiley J. W., (2005) Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1. J. Biol. Chem. 280, 618-627. (Pubitemid 40165028)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.1 , pp. 618-627
    • Hong, S.1    Wiley, J.W.2
  • 25
    • 34047262030 scopus 로고    scopus 로고
    • The effect of low-dose insulin on mechanical sensitivity and allodynia in type I diabetes neuropathy
    • DOI 10.1016/j.neulet.2007.02.087, PII S0304394007001978
    • Hoybergs Y. M., and, Meert T. F., (2007) The effect of low-dose insulin on mechanical sensitivity and allodynia in type I diabetes neuropathy. Neurosci. Lett. 417, 149-154. (Pubitemid 46551356)
    • (2007) Neuroscience Letters , vol.417 , Issue.2 , pp. 149-154
    • Hoybergs, Y.M.J.J.1    Meert, T.F.2
  • 26
    • 0029921401 scopus 로고    scopus 로고
    • Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunits
    • Ikeda S. R., (1996) Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunits. Nature 380, 255-258.
    • (1996) Nature , vol.380 , pp. 255-258
    • Ikeda, S.R.1
  • 28
    • 0030769845 scopus 로고    scopus 로고
    • 2+ channels in rat intracardiac neurons via a PTX- and voltage-sensitive pathway
    • Jeong S. W., and, Wurster R. D., (1997) Muscarinic receptor activation modulates Ca2+ channels in rat intracardiac neurons via a PTX- and voltage-sensitive pathway. J. Neurophysiol. 78, 1476-1490. (Pubitemid 27400688)
    • (1997) Journal of Neurophysiology , vol.78 , Issue.3 , pp. 1476-1490
    • Jeong, S.-W.1    Wurster, R.D.2
  • 29
    • 0036774152 scopus 로고    scopus 로고
    • Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats
    • DOI 10.1016/S0306-4522(02)00372-X, PII S030645220200372X
    • Khan G. M., Chen S. R., and, Pan H. L., (2002) Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats. Neuroscience 114, 291-299. (Pubitemid 35245410)
    • (2002) Neuroscience , vol.114 , Issue.2 , pp. 291-299
    • Khan, G.M.1    Chen, S.-R.2    Pan, H.-L.3
  • 30
    • 0036196408 scopus 로고    scopus 로고
    • Phenotype and function of somatic primary afferent nociceptive neurones with C-, Aδ- or Aα/β-fibres
    • DOI 10.1113/eph8702350
    • Lawson S. N., (2002) Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres. Exp. Physiol. 87, 239-244. (Pubitemid 34257039)
    • (2002) Experimental Physiology , vol.87 , Issue.2 , pp. 239-244
    • Lawson, S.N.1
  • 31
    • 0031775954 scopus 로고    scopus 로고
    • A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats
    • DOI 10.1016/S0304-3959(98)00037-2, PII S0304395998000372
    • Malcangio M., and, Tomlinson D. R., (1998) A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats. Pain 76, 151-157. (Pubitemid 28304951)
    • (1998) Pain , vol.76 , Issue.1-2 , pp. 151-157
    • Malcangio, M.1    Tomlinson, D.R.2
  • 32
    • 0026650993 scopus 로고
    • Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons
    • Mathie A., Bernheim L., and, Hille B., (1992) Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons. Neuron 8, 907-914.
    • (1992) Neuron , vol.8 , pp. 907-914
    • Mathie, A.1    Bernheim, L.2    Hille, B.3
  • 33
    • 69049097005 scopus 로고    scopus 로고
    • In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy
    • Messinger R. B., Naik A. K., Jagodic M. M., Nelson M. T., Lee W. Y., Choe W. J., Orestes P., Latham J. R., Todorovic S. M., and, Jevtovic-Todorovic V., (2009) In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy. Pain 145, 184-195.
    • (2009) Pain , vol.145 , pp. 184-195
    • Messinger, R.B.1    Naik, A.K.2    Jagodic, M.M.3    Nelson, M.T.4    Lee, W.Y.5    Choe, W.J.6    Orestes, P.7    Latham, J.R.8    Todorovic, S.M.9    Jevtovic-Todorovic, V.10
  • 34
    • 0026492964 scopus 로고
    • Binding and functional selectivity of himbacine for cloned and neuronal muscarinic receptors
    • Miller J. H., Aagaard P. J., Gibson V. A., and, McKinney M., (1992) Binding and functional selectivity of himbacine for cloned and neuronal muscarinic receptors. J. Pharmacol. Exp. Ther. 263, 663-667.
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , pp. 663-667
    • Miller, J.H.1    Aagaard, P.J.2    Gibson, V.A.3    McKinney, M.4
  • 35
    • 0028356074 scopus 로고
    • 2 receptor systems
    • Naguib M., and, Yaksh T. L., (1994) Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with mu and alpha 2 receptor systems. Anesthesiology 80, 1338-1348. (Pubitemid 24182608)
    • (1994) Anesthesiology , vol.80 , Issue.6 , pp. 1338-1348
    • Naguib, M.1    Yaksh, T.L.2
  • 37
  • 38
    • 0037207469 scopus 로고    scopus 로고
    • Molecular physiology of low-voltage-activated T-type calcium channels
    • Perez-Reyes E., (2003) Molecular physiology of low-voltage-activated t-type calcium channels. Physiol. Rev. 83, 117-161. (Pubitemid 36459879)
    • (2003) Physiological Reviews , vol.83 , Issue.1 , pp. 117-161
    • Perez-Reyes, E.1
  • 39
    • 0032567790 scopus 로고    scopus 로고
    • Hyperalgesia and decreased neuronal nitric oxide synthase in diabetic rats
    • Sasaki T., Yasuda H., Maeda K., and, Kikkawa R., (1998) Hyperalgesia and decreased neuronal nitric oxide synthase in diabetic rats. Neuroreport 9, 243-247. (Pubitemid 28081396)
    • (1998) NeuroReport , vol.9 , Issue.2 , pp. 243-247
    • Sasaki, T.1    Yasuda, H.2    Maeda, K.3    Kikkawa, R.4
  • 40
    • 0026502169 scopus 로고
    • Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size
    • Scroggs R. S., and, Fox A. P., (1992) Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size. J. Physiol. 445, 639-658.
    • (1992) J. Physiol. , vol.445 , pp. 639-658
    • Scroggs, R.S.1    Fox, A.P.2
  • 41
    • 0037743562 scopus 로고    scopus 로고
    • A T-type calcium channel required for normal function of a mammalian mechanoreceptor
    • DOI 10.1038/nn1076
    • Shin J. B., Martinez-Salgado C., Heppenstall P. A., and, Lewin G. R., (2003) A T-type calcium channel required for normal function of a mammalian mechanoreceptor. Nat. Neurosci. 6, 724-730. (Pubitemid 36792887)
    • (2003) Nature Neuroscience , vol.6 , Issue.7 , pp. 724-730
    • Shin, J.-B.1    Martinez-Salgado, C.2    Heppenstall, P.A.3    Lewin, G.R.4
  • 42
    • 0024445215 scopus 로고
    • Antinociceptive effect of spinal cholinergic stimulation: Interaction with substance P
    • DOI 10.1016/0024-3205(89)90127-6
    • Smith M. D., Yang X. H., Nha J. Y., and, Buccafusco J. J., (1989) Antinociceptive effect of spinal cholinergic stimulation: interaction with substance P. Life Sci. 45, 1255-1261. (Pubitemid 19249656)
    • (1989) Life Sciences , vol.45 , Issue.14 , pp. 1255-1261
    • Smith, M.D.1    Yang, X.2    Nha, J.-Y.3    Buccafusco, J.J.4
  • 43
    • 0033560089 scopus 로고    scopus 로고
    • Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels
    • Talley E. M., Cribbs L. L., Lee J. H., Daud A., Perez-Reyes E., and, Bayliss D. A., (1999) Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels. J. Neurosci. 19, 1895-1911. (Pubitemid 29133368)
    • (1999) Journal of Neuroscience , vol.19 , Issue.6 , pp. 1895-1911
    • Talley, E.M.1    Cribbs, L.L.2    Lee, J.-H.3    Daud, A.4    Perez-Reyes, E.5    Bayliss, D.A.6
  • 44
    • 0034693250 scopus 로고    scopus 로고
    • Muscarinic receptor subtypes expression in rat and chick dorsal root ganglia
    • Tata A. M., Vilaro M. T., and, Mengod G., (2000) Muscarinic receptor subtypes expression in rat and chick dorsal root ganglia. Brain Res. Mol. Brain Res. 82, 1-10.
    • (2000) Brain Res. Mol. Brain Res. , vol.82 , pp. 1-10
    • Tata, A.M.1    Vilaro, M.T.2    Mengod, G.3
  • 45
    • 50349092303 scopus 로고    scopus 로고
    • Painful diabetic neuropathy: Epidemiology, natural history, early diagnosis, and treatment options
    • Veves A., Backonja M., and, Malik R. A., (2008) Painful diabetic neuropathy: epidemiology, natural history, early diagnosis, and treatment options. Pain Med. 9, 660-674.
    • (2008) Pain Med. , vol.9 , pp. 660-674
    • Veves, A.1    Backonja, M.2    Malik, R.A.3
  • 46
    • 33947165254 scopus 로고    scopus 로고
    • Altered synaptic input and GABAB receptor function in spinal superficial dorsal horn neurons in rats with diabetic neuropathy
    • Wang X. L., Zhang H. M., Chen S. R., and, Pan H. L., (2007) Altered synaptic input and GABAB receptor function in spinal superficial dorsal horn neurons in rats with diabetic neuropathy. J. Physiol. 579, 849-861.
    • (2007) J. Physiol. , vol.579 , pp. 849-861
    • Wang, X.L.1    Zhang, H.M.2    Chen, S.R.3    Pan, H.L.4
  • 47
    • 0028173986 scopus 로고
    • Muscarinic regulation of Ca2+ currents in rat sensory neurons: Channel and receptor types, dose-response relationships and cross-talk pathways
    • Wanke E., Bianchi L., Mantegazza M., Guatteo E., Mancinelli E., and, Ferroni A., (1994) Muscarinic regulation of Ca2+ currents in rat sensory neurons: channel and receptor types, dose-response relationships and cross-talk pathways. Eur. J. Neurosci. 6, 381-391.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 381-391
    • Wanke, E.1    Bianchi, L.2    Mantegazza, M.3    Guatteo, E.4    Mancinelli, E.5    Ferroni, A.6
  • 48
    • 0029789994 scopus 로고    scopus 로고
    • Molecular biology of muscarinic acetylcholine receptors
    • Wess J., (1996) Molecular biology of muscarinic acetylcholine receptors. Crit. Rev. Neurobiol. 10, 69-99. (Pubitemid 26283956)
    • (1996) Critical Reviews in Neurobiology , vol.10 , Issue.1 , pp. 69-99
    • Wess, J.1
  • 49
    • 64149083515 scopus 로고    scopus 로고
    • A functional link between T-type calcium channels and mu-opioid receptor expression in adult primary sensory neurons
    • Wu Z. Z., Cai Y. Q., and, Pan H. L., (2009) A functional link between T-type calcium channels and mu-opioid receptor expression in adult primary sensory neurons. J. Neurochem. 109, 867-878.
    • (2009) J. Neurochem. , vol.109 , pp. 867-878
    • Wu, Z.Z.1    Cai, Y.Q.2    Pan, H.L.3
  • 50
    • 18044366205 scopus 로고    scopus 로고
    • M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons
    • Zhang H. M., Li D. P., Chen S. R., and, Pan H. L., (2005) M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons. J. Pharmacol. Exp. Ther. 313, 697-704.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 697-704
    • Zhang, H.M.1    Li, D.P.2    Chen, S.R.3    Pan, H.L.4
  • 51
    • 33846464673 scopus 로고    scopus 로고
    • Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes
    • Zhang H. M., Chen S. R., and, Pan H. L., (2007a) Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes. J. Neurophysiol. 97, 102-109.
    • (2007) J. Neurophysiol. , vol.97 , pp. 102-109
    • Zhang, H.M.1    Chen, S.R.2    Pan, H.L.3
  • 52
    • 36349032380 scopus 로고    scopus 로고
    • Control of glycinergic input to spinal dorsal horn neurons by distinct muscarinic receptor subtypes revealed using knockout mice
    • DOI 10.1124/jpet.107.127795
    • Zhang H. M., Zhou H. Y., Chen S. R., Gautam D., Wess J., and, Pan H. L., (2007b) Control of glycinergic input to spinal dorsal horn neurons by distinct muscarinic receptor subtypes revealed using knockout mice. J. Pharmacol. Exp. Ther. 323, 963-971. (Pubitemid 350146072)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.323 , Issue.3 , pp. 963-971
    • Zhang, H.-M.1    Zhou, H.-Y.2    Chen, S.-R.3    Gautam, D.4    Wess, J.5    Pan, H.-L.6
  • 53
    • 0025812344 scopus 로고
    • Tonic cholinergic inhibition of spinal mechanical transmission
    • Zhuo M., and, Gebhart G. F., (1991) Tonic cholinergic inhibition of spinal mechanical transmission. Pain 46, 211-222.
    • (1991) Pain , vol.46 , pp. 211-222
    • Zhuo, M.1    Gebhart, G.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.