A melting curve analysis-based PCR assay for one-step genotyping of β-thalassemia mutations: A multicenter validation

Journal of Molecular Diagnostics

Volumn 13, Issue 4, 2011, Pages 427-435

  Xiong, Fu ^a   Huang, Qiuying ^b   Chen, Xiaoyun ^b   Zhou, Yuqiu ^c   Zhang, Xinhua ^d   Cai, Ren ^e   Chen, Yajun ^f   Xie, Jiansheng ^g   Feng, Shanwei ^h   Wei, Xiaofeng ^a   Xiao, Qizhi ^c   Zhang, Tianlang ^d   Luo, Shiqiang ^e   Yang, Xuehuang ^f   Hao, Ying ^g   Qu, Yanxia ^h   Li, Qingge ^b   Xu, Xiangmin ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

^c Zhuhai Institute of Medical Genetics   (China)

^d The 303rd Hospital of PLA   (China)

^e Liuzhou Municipal Maternity and Child Healthcare Hospital   (China)

^f Shaoguan Municipal Maternity and Child Healthcare Hospital   (China)

^g Nanfang Medical University   (China)

^h Guangzhou Institute of Population and Family Planning   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BETA THALASSEMIA; CHINESE; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC ACCURACY; DNA DETERMINATION; GENE MUTATION; GENOTYPE; HIGH RESOLUTION MELTING ANALYSIS; HUMAN; MULTICENTER STUDY (TOPIC); POLYMERASE CHAIN REACTION; RELIABILITY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS; CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; GENETICS; LIMIT OF DETECTION; METHODOLOGY; MOLECULAR DIAGNOSIS; MULTICENTER STUDY; NUCLEOTIDE SEQUENCE; TRANSITION TEMPERATURE; VALIDATION STUDY;

BETA GLOBULIN;

BETA-GLOBULINS; BETA-THALASSEMIA; DNA MUTATIONAL ANALYSIS; DOUBLE-BLIND METHOD; HUMANS; LIMIT OF DETECTION; MOLECULAR DIAGNOSTIC TECHNIQUES; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; TRANSITION TEMPERATURE;

EID: 80054061119     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmoldx.2011.03.005     Document Type: Article

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