Rapid detection of β-globin gene (HBB) mutations coupling heteroduplex and primer-extension analysis by DHPLC

Human Mutation

Volumn 22, Issue 4, 2003, Pages 326-336

  Su, Yi Ning ^a   Lee, Chien Nan ^a   Hung, Chia Cheng ^b   Chen, Chi An ^a   Cheng, Wen Fang ^a   Tsao, Po Nien ^a   Yu, Chia Li ^a   Hsieh, Fon Jou ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Beta thalassemia; DHPLC; Globin, beta; HBB; Heteroduplex analysis; Mutation screening; Primer extension analysis

Indexed keywords

BETA GLOBIN; HETERODUPLEX; PRIMER DNA;

ALLELE; ARTICLE; BETA THALASSEMIA; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DNA DENATURATION; ELUTION; GENE MUTATION; GENE SEQUENCE; GENETIC SCREENING; HETEROZYGOTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOZYGOSITY; HUMAN; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCREENING TEST; SEQUENCE ANALYSIS; TAIWAN;

BASE SEQUENCE; BETA-THALASSEMIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA MUTATIONAL ANALYSIS; GENETIC SCREENING; GLOBINS; HETERODUPLEX ANALYSIS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; TIME FACTORS;

EID: 0141642025     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.10265     Document Type: Article

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