Stable and reproducible engraftment of primary adult and pediatric acute myeloid leukemia in NSG mice

Leukemia

Volumn 25, Issue 10, 2011, Pages 1635-1639

  Malaise M ^a   Neumeier, M ^a   Botteron, C ^a   Dohner K ^b   Reinhardt, D ^c   Schlegelberger, B ^d   Gohring G ^d   Gruhn, B ^e   Debatin, K M ^b   Corbacioglu, S ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY HOSPITAL ULM   (Germany)

^c LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ACUTE GRANULOCYTIC LEUKEMIA; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD CELL COUNT; CONTROLLED STUDY; CYTOGENETICS; DNA EXTRACTION; ENGRAFTMENT; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HEPATOSPLENOMEGALY; LETTER; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; THROMBOCYTOPENIA; TUMOR VOLUME;

ADULT; ANIMALS; BONE MARROW TRANSPLANTATION; CELL DIVISION; CHILD; FLOW CYTOMETRY; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 80054029105     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.121     Document Type: Letter

References (8)

1. Shultz LD, Pearson T, King M, Giassi L, Carney L, Gott B et al. Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research. Ann NY Acad Sci 2007; 1103: 77-89. (Pubitemid 46791104)
2. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S et al. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 2005; 174: 6477-6489. (Pubitemid 40663843)
3. Ishikawa F, Yoshida S, Saito Y, Hijikata A, Kitamura H, Tanaka S et al. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region. Nat Biotechnol 2007; 25: 1315-1321. (Pubitemid 350076512)
4. Agliano A, Martin-Padura I, Mancuso P, Marighetti P, Rabascio C, Pruneri G et al. Human acute leukemia cells injected in NOD/LtSzscid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains. Int J Cancer 2008; 123: 2222-2227.
5. Sanchez PV, Perry RL, Sarry JE, Perl AE, Murphy K, Swider CR et al. A robust xenotransplantation model for acute myeloid leukemia. Leukemia 2009; 23: 2109-2117.
6. Willasch AM, Gruhn B, Coliva T, Kalinova M, Schneider G, Kreyenberg H et al. Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study. Leukemia 2009; 23: 1472-1479.
7. Wunderlich M, Chou FS, Link KA, Mizukawa B, Perry RL, Carroll M et al. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3. Leukemia 2010; 24: 1785-1788.
8. Nicolini FE, Cashman JD, Hogge DE, Humphries RK, Eaves CJ. NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration. Leukemia 2004; 18: 341-347. (Pubitemid 38240052)