Group I mGlur activation reverses cocaine-induced accumulation of calcium-permeable AMPA receptors in nucleus accumbens synapses via a protein kinase C-dependent mechanism

Journal of Neuroscience

Volumn 31, Issue 41, 2011, Pages 14536-14541

  McCutcheon, James E ^a   Loweth, Jessica A ^a   Ford, Kerstin A ^a   Marinelli, Michela ^a   Wolf, Marina E ^a   Tseng, Kuei Y ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DIHYDROXYPHENYLGLYCINE; AMPA RECEPTOR; CALCIUM ION; CANNABINOID 1 RECEPTOR; COCAINE; METABOTROPIC RECEPTOR 1; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSOCIATION; BIOACCUMULATION; BRAIN SLICE; CALCIUM CONDUCTANCE; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG EFFECT; FACILITATION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SYNAPSE; SYNAPTIC TRANSMISSION; WITHDRAWAL SYNDROME;

ANIMALS; BENZOXAZINES; BIOPHYSICS; CALCIUM; CALCIUM CHANNEL BLOCKERS; COCAINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; MALE; METHOXYHYDROXYPHENYLGLYCOL; MORPHOLINES; NAPHTHALENES; NEURONS; NUCLEUS ACCUMBENS; PATCH-CLAMP TECHNIQUES; PIPERIDINES; PROTEIN KINASE C; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; SYNAPSES;

EID: 80054016349     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3625-11.2011     Document Type: Article

References (34)

1. Bellone C, Lüscher C (2005) mGluRs induce a long-term depression in the ventral tegmental area that involves a switch of the subunit composition of AMPA receptors. Eur J Neurosci 21:1280-1288
2. Bellone C, Lüscher C (2006) Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression. Nat Neurosci 9:636-641
3. Ben-Shahar O, Obara I, Ary AW, Ma N, Mangiardi MA, Medina RL, Szumlinski KK (2009) Extended daily access to cocaine results in distinct alterations in Homer 1b/c and NMDA receptor subunit expression within the medial prefrontal cortex. Synapse 63:598-609
4. Boudreau AC, Reimers JM, Milovanovic M, Wolf ME (2007) Cell surface AMPA receptors in the rat nucleus accumbens increase during cocaine withdrawal but internalize after cocaine challenge in association with altered activation of mitogen-activated protein kinases. J Neurosci 27:10621-10635
5. Conrad KL, Tseng KY, Uejima JL, Reimers JM, Heng LJ, Shaham Y, Marinelli M, Wolf ME (2008) Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving. Nature 454:118-121
6. 2+-permeable AMPA receptors: synaptic plasticity and beyond. Curr Opin Neurobiol 16:288-297
7. Fourgeaud L, Mato S, Bouchet D, Hémar A, Worley PF, Manzoni OJ (2004) A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens. J Neurosci 24:6939-6945
8. Groenewegen HJ, Wright CI, Beijer AV, Voorn P (1999) Convergence and segregation of ventral striatal inputs and outputs. Ann N Y Acad Sci 877:49-63
9. Hao Y, Martin-Fardon R, Weiss F (2010) Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence. Biol Psychiatry 68:240-248
10. Hu XT, White FJ (1996) Glutamate receptor regulation of rat nucleus accumbens neurons in vivo. Synapse 23:208-218
11. Isaac JT, Ashby MC, McBain CJ (2007) The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity. Neuron 54:859-871
12. Kalivas PW, Volkow ND (2005) The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry 162:1403-1413
13. Kamboj SK, Swanson GT, Cull-Candy SG (1995) Intracellular spermine confers rectification on rat calcium-permeable AMPA and kainate receptors. J Physiol 486:297-303
14. Kano M, Hashimoto K, Tabata T (2008) Type-1 metabotropic glutamate receptor in cerebellar Purkinje cells: a key molecule responsible for longterm depression, endocannabinoid signalling and synapse elimination. Philos Trans R Soc Lond B Biol Sci 363:2173-2186
15. Kelley AE (2004) Ventral striatal control of appetitive motivation: role in ingestive behavior and reward-related learning. Neurosci Biobehav Rev 27:765-776
16. Kelly L, Farrant M, Cull-Candy SG (2009) Synaptic mGluR activation drives plasticity of calcium-permeable AMPA receptors. Nat Neurosci 12: 593-601
17. 2+-permeable AMPA receptors in synaptic plasticity and neuronal death. Trends Neurosci 30:126-134
18. Liu SQ, Cull-Candy SG (2000) Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype. Nature 405: 454-458
19. Lovinger DM (2008) Presynaptic modulation by endocannabinoids. Handb Exp Pharmacol 184:435-477
20. Lu L, Grimm JW, Hope BT, Shaham Y (2004) Incubation of cocaine craving after withdrawal: a review of preclinical data. Neuropharmacology 47 [Suppl 1]:214-226
21. Mameli M, Balland B, Lújan R, Lüscher C (2007) Rapid synthesis and synaptic insertion of GluR2 for mGluR-LTD in the ventral tegmental area. Science 317:530-533
22. Mameli M, Halbout B, Creton C, Engblom D, Parkitna JR, Spanagel R, Lüscher C (2009) Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc. Nat Neurosci 12:1036-1041
23. Mangiavacchi S, Wolf ME (2004) Stimulation of N-methyl-D-aspartate receptors, AMPA receptors or metabotropic glutamate receptors leads to rapid internalization of AMPA receptors in cultured nucleus accumbens neurons. Eur J Neurosci 20:649-657
24. McCutcheon JE, Wang X, Tseng KY, Wolf ME, Marinelli M (2011) Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. J Neurosci 31:5737-5743
25. Mu P, Moyer JT, Ishikawa M, Zhang Y, Panksepp J, Sorg BA, Schlüter OM, Dong Y (2010) Exposure to cocaine dynamically regulates the intrinsic membrane excitability of nucleus accumbens neurons. J Neurosci 30:3689-3699
26. O'Brien CP, Childress AR, McLellan AT, Ehrman R (1992) Classical conditioning in drug-dependent humans. Ann N Y Acad Sci 654:400-415
27. Olive MF (2009) Metabotropic glutamate receptor ligands as potential therapeutics for addiction. Curr Drug Abuse Rev 2:83-998
28. Orio L, Edwards S, George O, Parsons LH, Koob GF (2009) A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions. J Neurosci 29:4846-4857
29. Pennartz CM, Boeijinga PH, Lopes da Silva FH (1990) Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA. Brain Res 529:30-41
30. Reimers JM, Milovanovic M, Wolf ME (2011) Quantitative analysis of AMPA receptor subunit composition in addiction-related brain regions. Brain Res 1367:223-233
31. Robbe D, Kopf M, Remaury A, Bockaert J, Manzoni OJ (2002) Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens. Proc Natl Acad Sci U S A 99:8384-8388
32. Shaham Y, Shalev U, Lu L, De Wit H, Stewart J (2003) The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl) 168:3-20
33. Wolf ME (2010) The Bermuda triangle of cocaine-induced neuroadaptations. Trends Neurosci 33:391-398
34. Wolf ME, Ferrario CR (2010) AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine. Neurosci Biobehav Rev 35: 185-211.