Expression of yeast high mobility group protein HMO1 is regulated by TOR signaling

Gene

Volumn 489, Issue 1, 2011, Pages 55-62

  Xiao, LiJuan ^a   Kamau, Edwin ^a   Donze, David ^a   Grove, Anne ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

galactosidase assay; ChIP; Fhl1; HMGB; Saccharomyces cerevisiae; TOR kinase

Indexed keywords

BETA GALACTOSIDASE; FORKHEAD TRANSCRIPTION FACTOR; HIGH MOBILITY GROUP B1 PROTEIN; RIBOSOME PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR FOXC1;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; GENE REPRESSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; YEAST;

FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, FUNGAL; HIGH MOBILITY GROUP PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEINS; RIBOSOMES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SIROLIMUS;

SACCHAROMYCES CEREVISIAE;

EID: 80053998078     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2011.08.017     Document Type: Article

References (34)

1. Bauerle K.T., Kamau E., Grove A. Interactions between N- and C-terminal domains of the Saccharomyces cerevisiae high-mobility group protein HMO1 are required for DNA bending. Biochemistry 2006, 45:3635-3645.
2. Berger A.B., Decourty L., Badis G., Nehrbass U., Jacquier A., Gadal O. Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription. Mol. Cell. Biol. 2007, 27:8015-8026.
3. Gadal O., Labarre S., Boschiero C., Thuriaux P. Hmo1, an HMG-box protein, belongs to the yeast ribosomal DNA transcription system. EMBO J. 2002, 21:5498-5507.
4. Gingras A.C., Raught B., Sonenberg N. Regulation of translation initiation by FRAP/mTOR. Genes Dev. 2001, 15:807-826.
5. Grummt I. Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus. Genes Dev. 2003, 17:1691-1702.
6. Hall D.B., Wade J.T., Struhl K. An HMG protein, Hmo1, associates with promoters of many ribosomal protein genes and throughout the rRNA gene locus in Saccharomyces cerevisiae. Mol. Cell. Biol. 2006, 26:3672-3679.
7. Hardwick J.S., Kuruvilla F.G., Tong J.K., Shamji A.F., Schreiber S.L. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:14866-14870.
8. Hay N., Sonenberg N. Upstream and downstream of mTOR. Genes Dev. 2004, 18:1926-1945.
9. Ho Y., et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 2002, 415:180-183.
10. Ito T., Chiba T., Ozawa R., Yoshida M., Hattori M., Sakaki Y. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:4569-4574.
11. Jorgensen P., Rupes I., Sharom J.R., Schneper J., Broach J.R., Tyers M. A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes Dev. 2004, 18:2491-2505.
12. Kamau, E., 2005. DNA supercoiling with a twist, Dissertation, Louisiana State University.
13. Kamau E., Bauerle K.T., Grove A. The Saccharomyces cerevisiae high mobility group box protein HMO1 contains two functional DNA binding domains. J. Biol. Chem. 2004, 279:55234-55240.
14. Kasahara K., et al. Assembly of regulatory factors on rRNA and ribosomal protein genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 2007, 27:6686-6705.
15. Kasahara K., Ki S., Aoyama K., Takahashi H., Kokubo T. Saccharomyces cerevisiae HMO1 interacts with TFIID and participates in start site selection by RNA polymerase II. Nucleic Acids Res. 2008, 36:1343-1357.
16. Kasahara K., Ohyama Y., Kokubo T. Hmo1 directs pre-initiation complex assembly to an appropriate site on its target gene promoters by masking a nucleosome-free region. Nucleic Acids Res. 2011, 39:4136-4150.
17. Lu J., Kobayashi R., Brill S.J. Characterization of a high mobility group 1/2 homolog in yeast. J. Biol. Chem. 1996, 271:33678-33685.
18. Marion R.M., et al. Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:14315-14322.
19. Martin D.E., Soulard A., Hall M.N. TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 2004, 119:969-979.
20. Merz K., Hondele M., Goetze H., Gmelch K., Stoeckl U., Griesenbeck J. Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules. Genes Dev. 2008, 22:1190-1204.
21. Powers T., Walter P. Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol. Biol. Cell 1999, 10:987-1000.
22. Rudra D., Zhao Y., Warner J.R. Central role of Ifh1p-Fhl1p interaction in the synthesis of yeast ribosomal proteins. EMBO J. 2005, 24:533-542.
23. Schawalder S.B., Kabani M., Howald I., Choudhury U., Werner M., Shore D. Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1. Nature 2004, 432:1058-1061.
24. Schmelzle T., Beck T., Martin D.E., Hall M.N. Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Mol. Cell. Biol. 2004, 24:338-351.
25. Schmitt M.E., Brown T.A., Trumpower B.L. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 1990, 18:3091-3092.
26. Shamji A.F., Kuruvilla F.G., Schreiber S.L. Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins. Curr. Biol. 2000, 10:1574-1581.
27. Sikorski R.S., Hieter P. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 1989, 122:19-27.
28. Simms T.A., Miller E.C., Buisson N.P., Jambunathan N., Donze D. The Saccharomyces cerevisiae TRT2 tRNAThr gene upstream of STE6 is a barrier to repression in MATalpha cells and exerts a potential tRNA position effect in MATa cells. Nucleic Acids Res. 2004, 32:5206-5213.
29. Tsang C.K., Zheng X.F. TOR-in(g) the nucleus. Cell Cycle 2007, 6:25-29.
30. Wade J.T., Hall D.B., Struhl K. The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes. Nature 2004, 432:1054-1058.
31. Xiao L., Grove A. Coordination of ribosomal protein and ribosomal RNA gene expression in response to TOR signaling. Curr. Genomics 2009, 10:198-205.
32. Xiao L., Williams A.M., Grove A. The C-terminal domain of yeast high mobility group protein HMO1 mediates lateral protein accretion and in-phase DNA bending. Biochemistry 2010, 49:4051-4059.
33. Zaragoza D., Ghavidel A., Heitman J., Schultz M.C. Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway. Mol. Cell. Biol. 1998, 18:4463-4470.
34. Zhao Y., McIntosh K.B., Rudra D., Schawalder S., Shore D., Warner J.R. Fine-structure analysis of ribosomal protein gene transcription. Mol. Cell. Biol. 2006, 26:4853-4862.