Biochemical characterization of ethanol-dependent reduction of furfural by alcohol dehydrogenases

Biodegradation

Volumn 22, Issue 6, 2011, Pages 1227-1237

  Li, Qunrui ^a   Lam, L K Metthew ^a   Xun, Luying ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Ethanol; Furfural; Furfural reductase; Furfuryl alcohol; Zn dependent alcohol dehydrogenase

Indexed keywords

ALCOHOL DEHYDROGENASE; BIOCHEMICAL CHARACTERIZATION; BIOREDUCTIONS; COUPLED REACTION; FREE ENERGY CHANGE; FURFURYL ALCOHOL; HIGH AFFINITY; KINETIC DATA; LAG PHASE; LIGNOCELLULOSIC BIOMASS; REDUCING POWER; SUGAR DERIVATIVES; ZN-DEPENDENT ALCOHOL DEHYDROGENASE;

CATALYSTS; ENZYME ACTIVITY; ETHANOL; FURFURAL; SUGARS; TOXIC MATERIALS; ZINC;

ALDEHYDES;

ALCOHOL; ALCOHOL DEHYDROGENASE; BACTERIAL PROTEIN; FURAN DERIVATIVE; FURFURAL; FURFURYL ALCOHOL; ISOENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; RECOMBINANT PROTEIN;

BIOCHEMICAL COMPOSITION; BIODEGRADATION; BIOMASS; ENZYME ACTIVITY; ETHANOL; PHYSIOLOGY; REACTION KINETICS; SUGAR; TOXICITY; YEAST;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM TRANSFORMATION; CHEMISTRY; CUPRIAVIDUS NECATOR; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MICROBIOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; PHYLOGENY; PLASMID; PSEUDOMONAS AERUGINOSA; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; THERMODYNAMICS;

ALCOHOL DEHYDROGENASE; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CLONING, MOLECULAR; CUPRIAVIDUS NECATOR; ESCHERICHIA COLI; ETHANOL; FURALDEHYDE; FURANS; INDUSTRIAL MICROBIOLOGY; ISOENZYMES; KINETICS; MOLECULAR SEQUENCE DATA; NAD; PHYLOGENY; PLASMIDS; PSEUDOMONAS AERUGINOSA; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; THERMODYNAMICS; TRANSFORMATION, BACTERIAL;

CUPRIAVIDUS NECATOR;

EID: 80053970816     PISSN: 09239820     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10532-011-9477-x     Document Type: Article

References (27)

1. Antal MJ, Leesomboon T, Mok WS, Richards GN (1991) Mechanism of formation of 2-furaldehyde from d-xylose. Carbohydr Res 217: 71-85.
2. Boopathy R, Bokang H, Daniels L (1993) Biotransformation of furfural and 5-hydroxymethyl furfural by enteric bacteria. J Ind Microbiol Biotechnol 11: 147-150.
3. Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
4. de Smidt O, du Preez JC, Albertyn J (2008) The alcohol dehydrogenases of Saccharomyces cerevisiae: a comprehensive review. FEMS Yeast Res 8: 967-978.
5. Ellis TG, Eliosov B (2004) Use of extant kinetic parameters to predict effluent concentrations of specific organic compounds at full-scale facilities. Water Environ Res 76: 444-452.
6. Ganzhorn AJ, Green DW, Hershey AD, Gould RM, Plapp BV (1987) Kinetic characterization of yeast alcohol dehydrogenases. Amino acid residue 294 and substrate specificity. J Biol Chem 262: 3754-3761.
7. Gutierrez T, Ingram LO, Preston JF (2006) Purification and characterization of a furfural reductase (FFR) from Escherichia coli strain LYO1: an enzyme important in the detoxification of furfural during ethanol production. J Biotechnol 121: 154-164.
8. Heer D, Sauer U (2008) Identification of furfural as a key toxin in lignocellulosic hydrolysates and evolution of a tolerant yeast strain. Microb Biotech 1: 497-506.
9. Hoydonckx HE, van Rhijn WM, van Rhijn W, De Vos DE, Jacobs PA (2007) "Furfural and derivatives" in Ullmann's encyclopedia of industrial chemistry. Wiley-VCH, Weinheim.
10. Karlsson A, El-Ahmad M, Johansson K, Shafqat J, Jörnvall H, Eklund H, Ramaswamy S (2003) Tetrameric NAD-dependent alcohol dehydrogenase. Chem Biol Interact 143-144: 239-245.
11. Laadan B, Almeida JR, Rådström P, Hahn-Hägerdal B, Gorwa-Grauslund M (2008) Identification of an NADH-dependent 5-hydroxymethylfurfural-reducing alcohol dehydrogenase in Saccharomyces cerevisiae. Yeast 25: 191-198.
12. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
13. Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H et al (2007) Clustal W and clustal X version 2.0. Bioinformatics 23: 2947-2948.
14. Larroy C, Pares X, Biosca JA (2002a) Characterization of a Saccharomyces cerevisiae NADP(H)-dependent alcohol dehydrogenase (ADHVII), a member of the cinnamyl alcohol dehydrogenase family. Eur J Biochem 269: 5738-5745.
15. Larroy C, Fernandez MR, Gonzalez E, Pares X, Biosca JA (2002b) Characterization of the Saccharomyces cerevisiae YMR318C (ADH6) gene product as a broad specificity NADPH-dependent alcohol dehydrogenase: relevance in aldehyde reduction. Biochem J 361: 163-172.
16. Levin I, Meiri G, Peretz M, Burstein Y, Frolow F (2004) The ternary complex of Pseudomonas aeruginosa alcohol dehydrogenase with NADH and ethylene glycol. Protein Sci 13: 1547-1556.
17. Li Q, Lam LKM, Xun L (2011) Cupriavidus necator JMP134 rapidly reduces furfural with a Zn-dependent alcohol dehydrogenase. Biodegradation. doi: 10. 1007/s10532-011-9476-y.
18. Liu ZL, Moon J (2009) A novel NADPH-dependent aldehyde reductase gene from Saccharomyces cerevisiae NRRL Y-12632 involved in the detoxification of aldehyde inhibitors derived from lignocellulosic biomass conversion. Gene 446: 1-10.
19. Liu ZL, Moon J, Andersh AJ, Slininger PJ, Weber S (2008) Multiple gene mediated NAD(P)H-dependent aldehyde reduction is a mechanism of in situ detoxification of furfural and HMF by ethanologenic yeast Saccharomyces cerevisiae. Appl Microbiol Biotechnol 81: 743-753.
20. Marchand P, Rosenfeld E, Erable B, Maugard T, Lamare T, Goubet I (2008) Coupled oxidation-reduction of butanol-hexanal by resting Rhodococcus erythropolis NCIMB 13064 cells in liquid and gas phases. Enz Microb Technol 43: 423-430.
21. Miller EN, Jarboe LR, Yomano LP, York SW, Shanmugam KT, Ingram LO (2009) Silencing of NADPH-dependent oxidoreductase genes (yqhD and dkgA) in furfural-resistant ethanologenic Escherichia coli. Appl Environ Microbiol 75: 4315-4323.
22. Modig T, Lidén G, Taherzadeh MJ (2002) Inhibition effects of furfural on alcohol dehydrogenase, aldehyde dehydrogenase and pyruvate dehydrogenase. Biochem J 363: 769-776.
23. O'Brien PJ, Siraki AG, Shangari N (2005) Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health. Crit Rev Toxicol 35: 609-662.
24. Sambrook J, Fritch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
25. Schenkels P, Duine JA (2000) Nicotinoprotein (NADH-containing) alcohol dehydrogenase from Rhodococcus erythropolis DSM 1069: an efficient catalyst for coenzyme-independent oxidation of a broad spectrum of alcohols and the interconversion of alcohols and aldehydes. Microbiology 146: 775-785.
26. Shafqat J, Höög JO, Hjelmqvist L, Oppermann UC, Ibáñez C, Jörnvall H (1999) An ethanol-inducible MDR ethanol dehydrogenase/acetaldehyde reductase in Escherichia coli: structural and enzymatic relationships to the eukaryotic protein forms. Eur J Biochem 263: 305-311.
27. Thauer RK, Jungermann K, Decker K (1977) Energy conservation in chemotropic anaerobic bacteria. Bacteriol Rev 41: 100-180.