Serum bicarbonate and mortality in stage 3 and stage 4 chronic kidney disease

Clinical Journal of the American Society of Nephrology

Volumn 6, Issue 10, 2011, Pages 2395-2402

  Navaneethan, Sankar D ^a   Schold, Jesse D ^a   Arrigain, Susana ^a   Jolly, Stacey E ^a   Wehbe, Edgard ^a   Raina, Rupesh ^a   Simon, James F ^a   Srinivas, Titte R ^a   Jain, Anil ^a   Schreiber Jr , Martin J ^a   Nally Jr , Joseph V ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE;

ADULT; AGED; ARTICLE; BICARBONATE BLOOD LEVEL; CAUSE OF DEATH; CHRONIC KIDNEY DISEASE; DIABETES MELLITUS; DISEASE COURSE; FEMALE; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY;

AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BICARBONATES; BIOLOGICAL MARKERS; CHI-SQUARE DISTRIBUTION; CHRONIC DISEASE; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; KIDNEY DISEASES; LOGISTIC MODELS; MALE; MIDDLE AGED; OHIO; PROPORTIONAL HAZARDS MODELS; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 80053925445     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.03730411     Document Type: Article

References (24)

1. Kraut JA, Kurtz I: Metabolic acidosis of CKD: Diagnosis, clinical characteristics, and treatment. Am J Kidney Dis 45: 978-993, 2005
2. Moranne O, Froissart M, Rossert J, Gauci C, Boffa JJ, Haymann JP, M'rad MB, Jacquot C, Houillier P, Stengel B, Fouqueray B: Timing of onset of CKD-related metabolic complications. J Am Soc Nephrol 20: 164-171, 2009
3. Domrongkitchaiporn S, Pongskul C, Sirikulchayanonta V, Stitchantrakul W, Leeprasert V, Ongphiphadhanakul B, Radinahamed P, Rajatanavin R: Bone histology and bone mineral density after correction of acidosis in distal renal tubular acidosis. Kidney Int 62: 2160-2166, 2002
4. Bailey JL, Wang X, England BK, Price SR, Ding X, Mitch WE: The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway. J Clin Invest 97: 1447-1453, 1996
5. Mitch WE, Price SR: Mechanisms activated by kidney disease and the loss of muscle mass. Am J Kidney Dis 38: 1337-1342, 2001
6. Ayus JC, Krothapalli RK: Effect of bicarbonate administration on cardiac function. Am J Med 87: 5-6, 1989
7. Mak RH: Effect of metabolic acidosis on insulin action and secretion in uremia. Kidney Int 54: 603-607, 1998
8. Pickering WP, Price SR, Bircher G, Marinovic AC, Mitch WE, Walls JL: Nutrition in CAPD: Serum bicarbonate and the ubiquitin-proteasome system in muscle. Kidney Int 61: 1286-1292, 2002
9. Khanna A, Kurtzman NA: Metabolic alkalosis. Respir Care 46: 354-365, 2001
10. Laski ME, Sabatini S: Metabolic alkalosis, bedside and bench. Semin Nephrol 26: 422-433, 2006
11. Kovesdy CP, Anderson JE, Kalantar-Zadeh K: Association of serum bicarbonate levels with mortality in patients with nondialysis-dependent CKD. Nephrol Dial Transplant 24: 1232-1237, 2009
12. Raphael KL, Wei G, Baird BC, Greene T, Beddhu S: Higher serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans. Kidney Int 79: 356-362, 2011
13. Navaneethan SD, Jolly SE, Schold JD, Arrigain S, Saupe W, Sharp J, Lyons J, Simon JF, Schreiber MJ Jr, Jain A, Nally JV: Development and validation of an electronic health recordbased chronic kidney disease registry. Clin J Am Soc Nephrol 6: 40-49, 2011
14. Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF, Feldman HI, Kusek JW, Eggers P, Van Lente F, Greene T, Coresh J: A new equation to estimate glomerular filtration rate. Ann Intern Med 150: 604-612, 2009
15. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Am J Kidney Dis 39: S1-S266, 2002
16. Menon V, Tighiouart H, Vaughn NS, Beck GJ, Kusek JW, Collins AJ, Greene T, Sarnak MJ: Serum bicarbonate and long-term outcomes in CKD. Am J Kidney Dis 56: 907-914, 2010
17. Mahajan A, Simoni J, Sheather SJ, Broglio KR, Rajab MH, Wesson DE: Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy. Kidney Int 78: 303-309, 2010
18. Brito-Ashurst I, Varagunam M, Raftery MJ, Yaqoob MM: Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol 20: 2075- 2084, 2009
19. Shah SN, Abramowitz M, Hostetter TH, Melamed ML: Serum bicarbonate levels and the progression of kidney disease: A cohort study. Am J Kidney Dis 54: 270-277, 2009
20. Yaqoob MM: Acidosis and progression of chronic kidney disease. Curr Opin Nephrol Hypertens 19: 489-492, 2010
21. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296-1305, 2004
22. Shlipak MG, Katz R, Kestenbaum BF, Siscovick D, Fried L, Newman A, Rifkin D, Sarnak MJ: Rapid decline of kidney function increases cardiovascular risk in the elderly. J Am Soc Nephrol 20: 2625-2630, 2009
23. Chiche JF, Brahimi-Horn MF, Pouyssegur J: Tumour hypoxia induces a metabolic shift causing acidosis: A common feature in cancer. J Cell Mol Med 14: 771-794, 2010
24. Cogan MG, Liu FY: Metabolic alkalosis in the rat: Evidence that reduced glomerular filtration rather than enhanced tubular bicarbonate reabsorption is responsible for maintaining the alkalotic state. J Clin Invest 71: 1141-1160, 1983