Elevating awareness and intake of choline: An essential nutrient for public health

Nutrition Today

Volumn 46, Issue 5, 2011, Pages 235-241

  Caudill, Marie ^a   Da Costa, Kerry Ann ^b   Zeisel, Steven ^c   Hornick, Betsy ^d  

^a Genomics at Cornell University ^*  (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d Specializing in Food Nutrition and Health Communications   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80053920850     PISSN: 0029666X     EISSN: 15389839     Source Type: Journal    
DOI: 10.1097/NT.0b013e31822dff64     Document Type: Article

References (33)

1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: National Academy Press; 1998:390-422.
2. Zeisel SH. Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr. 2006;26:229-250.
3. Zeisel SH, da Costa KA. Choline: an essential nutrient for public health. Nutr Rev. 2009;67:615-623.
4. Patterson KY, Bhagwat SA, Williams JR, et al. USDA Database for the Choline Content of Common Foods, Release 2. US Department of Agriculture, Agricultural Research Service. January 2008. http://www.nal.usda.gov/fnic/ foodcomp/Data/Choline/Choln02.pdf. Accessed December 1, 2009.
5. US Department of Agriculture, Center for Nutrition Policy and Promotion. Transcripts of the Fourth Meeting of the 2010 Dietary Guidelines Advisory Committee. November 4-5, 2009. http://www.cnpp.usda.gov/DGAsMeeting4.htm. Accessed December 7, 2009.
6. US Department of Agriculture, Agricultural Research Service. 2009. USDA National Nutrient Database for Standard Reference, Release 22. http://www.ars.usda.gov/ba/bhnrc/ndl. Accessed December 7, 2009.
7. Chiuve S, Giovannucci E, Handkinson S, et al. The association between betaine and choline intakes and the plasma concentrations of homocysteine in women. Am J Clin Nutr. 2007;86:1073-1081. (Pubitemid 47538311)
8. da Costa KA, Kozyreva OG, Song J, Galanko JA, Fischer LM, Zeisel SH. Common genetic polymorphisms affect the human requirement for the nutrient choline. Faseb J. 2006;20:1336-1344. (Pubitemid 44943841)
9. Kohlmeier M, da Costa KA, Fischer LM, Zeisel SH. Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc Natl Acad Sci USA. 2005;102:16025-16030. (Pubitemid 41552861)
10. Niculescu M, Zeisel S. Diet, methyl donors and DNA methylation: interaction between dietary folate, methionine, and choline. J Nutr. 2002;132(suppl):S2333-S2335.
11. US Department of Agriculture, Agricultural Research Service. 2008. Nutrient Intakes From Food: Mean Amounts Consumed per Individual, One Day, 2005-2006. http://www.ars.usda.gov/SP2UserFiles/Place/12355000/pdf/0506/Table-1- NIF-05.pdf. Accessed December 22, 2009.
12. Caudill MA. Pre-and postnatal health: evidence of increased choline needs. J Am Diet Assoc. 2010;110:1198-1206.
13. Vollset S, Refsum H, Irgens L, et al. Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine Study. Am J Clin Nutr. 2000;71:962-968. (Pubitemid 30176580)
14. Rees W, Wilson F, Maloney C. Sulfur amino acid metabolism in pregnancy: the impact of methionine in the maternal diet. J Nutr. 2006;136:1701S-1705S. (Pubitemid 43765383)
15. Shaw GM, Carmichael SL, Yang W, Selvin S, Schaffer DM. Periconceptional dietary intake of choline and betaine and neural tube defects in offspring. Am J Epidemiol. 2004;160:102-109. (Pubitemid 38962995)
16. Zeisel S, Niculescu M. Perinatal choline influences brain structure and function. Nutr Rev. 2006;64:197-203.
17. Molloy AM, Mills JL, Cox C, et al. Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery. Am J Clin Nutr. 2005;82(4):836-842. (Pubitemid 43779698)
18. Fisher MC, Zeisel SH, Mar MH, Sadler TW. Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. Faseb J. 2002;16:619-621.
19. Cheng RK, MacDonald CJ, Williams CL, Meck WH. Prenatal choline supplementation alters the timing, emotion, and memory performance (TEMP) of adult male and female rats as indexed by differential reinforcement of low-rate schedule behavior. Learn Mem. 2008;15:153-162. (Pubitemid 351439145)
20. Meck W, Williams C. Perinatal choline supplementation increases the threshold for chunking in spatial memory. Neuroreport. 1997;8:3053-3059. (Pubitemid 27421730)
21. Meck WH, Smith RA, Williams CL. Pre-and postnatal choline supplementation produces long-term facilitation of spatial memory. Dev Psychobiol. 1988;21(4):339-353.
22. Mellott TJ, Williams CL, Meck WH, Blusztajn JK. Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. FASEB J. 2004;18(3):545-547.
23. Meck WH, Williams CL. Metabolic imprinting of choline by its availability during gestation: implications for memory and attentional processing across the lifespan. Neurosci Biobehav Rev. 2003;27(4):385-399. (Pubitemid 36999837)
24. Thomas J, Biane J, OBryan K, O'Neill T, Dominguez H. Choline supplementation following third-semester-equivalent alcohol exposure attenuates behavioral alterations in rats. Behav Neurosci. 2007;121:120-130. (Pubitemid 46328630)
25. Wong-Goodrich SJ, Mellott TJ, Glenn MJ, Blusztajn JK, Williams CL. Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus. Neurobiol Dis. 2008;30:255-269.
26. Zeisel S. The fetal origins of memory: the role of dietary choline in optimal brain development. J Pediatr. 2006; 149:131S-136S.
27. Olthof M, Brink E, Katan M, Verhoef P. Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in health men. Am J Clin Nutr. 2005;82:111-117. (Pubitemid 41716383)
28. Detopoulou P, Panagiotakos DB, Antonopoulou S, Pitsavos C, Stefanadis C. Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study. Am J Clin Nutr. 2008;87:424-430. (Pubitemid 351226080)
29. Fargnoli JL, Fung TT, Olenczuk DM, Chamberland JP, Hu FB, Mantzoros CS. Adherence to healthy eating patterns is associated with higher circulating total and high-molecular-weight adiponectin and lower resistin concentrations in women from the Nurses' Health Study. Am J Clin Nutr. 2008;88:1213-1224.
30. US Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute (statement from Elizabeth G. Nabel, MD, Director, National Heart, Lung, and Blood Institute on New Findings on the Role of Inflammation in Prevention of Coronary Heart Disease). http://www.nih.gov/news/health/nov2008/nhlbi-10.htm. Accessed December 8, 2009.
31. Xu X, Gammon MD, Zeisel SH, et al. Choline metabolism and risk of breast cancer in a population-based study. FASEB J. 2008;22:2045-2052. (Pubitemid 351811480)
32. Solis C, Veenema K, Ivanov AA, et al. Folate intake at RDA levels is inadequate for Mexican American men with the methylenetetrahydrofolate reductase 677TT genotype. J Nutr. 2008;138:1-6.
33. StrategyOne Health Professionals Survey, March 2007. Online study among 252 health care professionals from Harris Interactive's Physicians and Specialty Health Professionals Panels. Sponsored by American Egg Board/Egg Nutrition Center. http://www.cholineinfo.org/healthcare-professionals/overview.asp. Accessed December 7, 2009.