A physiologically based model of hepatic ICG clearance: Interplay between sinusoidal uptake and biliary excretion

European Journal of Pharmaceutical Sciences

Volumn 44, Issue 3, 2011, Pages 359-365

  Weiss, Michael ^a   Krejcie, Tom C ^b   Avram, Michael J ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Biliary excretion; Dog; Hepatic uptake; ICG; Isoflurane; Pharmacokinetic model

Indexed keywords

INDOCYANINE GREEN; ISOFLURANE;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG EXCRETION; HEART OUTPUT; LIVER BLOOD FLOW; LIVER CLEARANCE; LIVER SINUSOID; NONHUMAN; PRIORITY JOURNAL; TIME TO MAXIMUM PLASMA CONCENTRATION; WAKEFULNESS;

ANESTHESIA, INHALATION; ANIMALS; BILE; BILE CANALICULI; COLORING AGENTS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOCYANINE GREEN; LIVER; LIVER CIRCULATION; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 80053917671     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.08.018     Document Type: Article

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