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Volumn , Issue 55, 2011, Pages

A high-throughput automated platform for the development of manufacturing cell lines for protein therapeutics

Author keywords

Automation; Cloneselect imager; FACS; FACS aria; High throughput; Issue 55; Manufacturing cell line; Medicine; Protein therapeutics; TECAN freedom EVO liquid handling system

Indexed keywords


EID: 80053916832     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/3010     Document Type: Article
Times cited : (20)

References (8)
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    • (1994) Biotechnol. Prog , vol.10 , Issue.3 , pp. 299-307
    • Kromenaker, S.J.1    Srienc, F.2
  • 4
    • 0025332641 scopus 로고
    • Selective cloning of hybridoma cells for enhanced immunoglobulin production using flow cytometric cell sorting and automated laser nephelometry
    • Marder, P., Maciak, R.S., Fouts, R.L., Baker, R.S., & Starling, J.J. Selective cloning of hybridoma cells for enhanced immunoglobulin production using flow cytometric cell sorting and automated laser nephelometry. Cytometry. 11 (4), 498-505 (1990).
    • (1990) Cytometry , vol.11 , Issue.4 , pp. 498-505
    • Marder, P.1    Maciak, R.S.2    Fouts, R.L.3    Baker, R.S.4    Starling, J.J.5
  • 5
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    • Improvements in cytogenetic slide preparation: Controlled chromosome spreading chemical aging and gradual denaturing
    • Henegariu, O., Heerema, N., Wright, L.L., Bray-Ward, P., Ward, D.C., & Vance, G.H. Improvements in cytogenetic slide preparation: controlled chromosome spreading chemical aging and gradual denaturing. Cytomery. 43 (2), 101-9 (2001).
    • (2001) Cytomery , vol.43 , Issue.2 , pp. 101-109
    • Henegariu, O.1    Heerema, N.2    Wright, L.L.3    Bray-Ward, P.4    Ward, D.C.5    Vance, G.H.6
  • 6
    • 0033969002 scopus 로고    scopus 로고
    • Grenn fluorescent protein (GFP) as a second selectable marker for selection of high producing clones from transfected CHO cells
    • Meng, Y.G. Grenn fluorescent protein (GFP) as a second selectable marker for selection of high producing clones from transfected CHO cells. Gene. 242, 201-207 (2000).
    • (2000) Gene , vol.242 , pp. 201-207
    • Meng, Y.G.1
  • 7
    • 34247280567 scopus 로고    scopus 로고
    • Accelerated clone selection for recombinant CHO cells using a FACS-based high-throughput screen
    • DeMaria, C.T., Cairns, V., Schwarz, C., Zhang, J., Guerin, M., Zuena, E., Estes, S., & Karey, K.P. Accelerated clone selection for recombinant CHO cells using a FACS-based high-throughput screen. Biotechnol. Prog. 23 (2), 465-472 (2007).
    • (2007) Biotechnol Prog , vol.23 , Issue.2 , pp. 465-472
    • Demaria, C.T.1    Cairns, V.2    Schwarz, C.3    Zhang, J.4    Guerin, M.5    Zuena, E.6    Estes, S.7    Karey, K.P.8
  • 8
    • 0030904484 scopus 로고    scopus 로고
    • Gel microdrop technology for rapid isolation of rare an high producer cells
    • Weaver, J.C. Gel microdrop technology for rapid isolation of rare an high producer cells. Nat. Med. 3, 583-585 (1997).
    • (1997) Nat. Med , vol.3 , pp. 583-585
    • Weaver, J.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.