Microcantilever sensing arrays from biodegradable, pH-responsive hydrogels

Biomedical Microdevices

Volumn 13, Issue 5, 2011, Pages 829-836

  Vanblarcom, Diana Snelling ^a   Peppas, Nicholas A ^a  

^a The University of Texas at Austin   (United States)

Author keywords

Biodegradable; Hydrogel; Microcantilever; pH responsive; Sensor

Indexed keywords

BEAM DEFLECTION; BIODEGRADABLE; BIOLOGICAL CONDITIONS; COMPOSITE CANTILEVER BEAMS; CROSSLINKED; DIACRYLATES; EQUILIBRIUM SWELLING; HIGH SENSITIVITY; MAXIMUM SENSITIVITY; MICRO-CANTILEVERS; MICROCANTILEVER ARRAYS; MOLAR PERCENTAGE; OPTICAL SIGNALS; ORGANOSILANE CHEMISTRY; PH-RESPONSIVE; PH-RESPONSIVE HYDROGELS; POLY (METHACRYLIC ACID); SENSING COMPONENTS; SILICON BEAMS; SILICON-BASED; THIN LAYERS; VOLUME CHANGE;

ADHESION; COMPOSITE MICROMECHANICS; CROSSLINKING; PHOTOPOLYMERIZATION; SENSORS;

HYDROGELS;

POLYCAPROLACTONE; POLYCAPROLACTONE DIACRYLATE; POLYMETHACRYLIC ACID; SILICON; UNCLASSIFIED DRUG;

ADHESION; ANALYTICAL PARAMETERS; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; CROSSLINKING RATIO; DEFLECTION; DRY WEIGHT; FLUORESCENCE MICROSCOPY; HYDROGEL; MATERIALS TESTING; MAXIMUM SENSITIVITY; MICROCANTILEVER SENSING ARRAY; MICROSENSOR; NANOARRAY; PH; PHOTOPOLYMERIZATION; POLYMERIZATION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SENSOR; SYNTHESIS; VOLUME SWELLING RATIO;

BUFFERS; EQUIPMENT DESIGN; HYDROGELS; HYDROGEN-ION CONCENTRATION; MICRO-ELECTRICAL-MECHANICAL SYSTEMS; OPTICAL PROCESSES; POLYESTERS; POLYMETHACRYLIC ACIDS; PROTEINS; SENSITIVITY AND SPECIFICITY; SOLUTIONS;

EID: 80053899484     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-011-9553-3     Document Type: Article

References (30)

1. R Bashir JZ Hilt O Elibol A Gupta NA Peppas 2002 Micromechanical cantilever as an ultrasensitive pH microsensor Appl. Phys. Lett. 81 3091 3093 10.1063/1.1514825 (Pubitemid 35328477)
2. C.L. Bayer, É. Pérez Herrero, N.A. Peppas, "Alginate Films as Macromolecular Imprinted Matrices", J. Biomater. Sci., Polym. Ed. 22, 1523-1534 (2011).
3. NM Bergmann NA Peppas 2008 Molecularly imprinted polymers with specific recognition for macromolecules and proteins Prog. Polym. Sci. 33 271 288 10.1016/j.progpolymsci.2007.09.004 (Pubitemid 351625301)
4. NM Bergmann EH Lauten NA Peppas 2005 Intelligent biomaterials for drug delivery: combining molecular recognition with drug delivery Drug Deliv Syst. Sci. 4 35 40
5. A Boisen T Thundat 2009 Design & fabrication of cantilever array biosensors Mater. Today 12 32 38 10.1016/S1369-7021(09)70249-4
6. T Boland BD Ratner 1995 Direct measurement of hydrogen bonding in DNA nucleotide bases by atomic force microscopy Proc. Natl Acad. Sci. U.S.A. 12 5297 5301 10.1073/pnas.92.12.5297
7. D.G. Buerk, Biosensors, Theory and Applications (Technomic Publishing Company, Inc, Lancaster, 1993)
8. ME Byrne E Oral JZ Hilt NA Peppas 2002 Networks for recognition of biomolecules: molecular imprinting and micropatterning poly(ethylene glycol)-Containing films Polym. Adv. Technol. 13 798 816 10.1002/pat.272 (Pubitemid 36230234)
9. M Caldorera-Moore NA Peppas 2009 Micro- and nanotechnologies for biomaterial-based medical systems Adv. Drug Deliv. Rev. 61 1391 1401 10.1016/j.addr.2009.09.002
10. A Chilkoti T Boland BD Ratner PS Stayton 1995 The relationship between ligand-binding thermodynamics and protein-ligand interaction forces measured by atomic force microscopy Biophys. J. 69 2125 2130 10.1016/S0006-3495(95)80083-4
11. W-H Chu M Mehregany RL Mullen 1993 Analysis of tip deflection and force bimetallic cantilever microactuator J. Micromech. Microeng. 3 4 7 10.1088/0960-1317/3/1/002
12. GP Gumbrell RA Peura S Kun RM Dunn 1998 Evaluation of a minimally invasive pH based microvascular ischemial monitor J. Clin. Eng. 23 344 353
13. PK Hansma VB Elings O Marti CE Bracker 1998 Scanning tunneling microscopy and atomic force microscopy: application to biology and technology Science 242 209 216 10.1126/science.3051380
14. D. Henthorn, Y. Zheng, N.A. Peppas, Synthetic ligand-receptor Interactions in Delivery Systems, in Nanotechnology in Therapeutics: Current Technology and Applications, ed. by N.A. Peppas, J.Z. Hilt, J.B. Thomas (Horizon Press, Norfolk, 2007)
15. J.Z. Hilt, Novel micro- and nanoscale diagnostic and therapeutic devices based on intelligent polymer networks, in chemical engineering (The University of Texas, Austin, 2004)
16. JZ Hilt NA Peppas 2005 Microfabricated drug delivery devices Int. J. Pharm. 306 15 23 10.1016/j.ijpharm.2005.09.022 (Pubitemid 41643137)
17. J.Z. Hilt, A.K. Gupta, R. Bashir, N.A. Peppas, A Microsensor Based on a Microcentilever Patterned with an Environmentally Sensitive Hydrogel, in BioMEMS and bionanotechnology, vol. 729, ed. by R.P. Manginell, J.T. Borenstein, L.P. Lee, P.J. Hesketh (MRS, Pittsburgh, 2002), pp. 173-178
18. H Kweon MK Yoo IK Park TH Kim HC Lee JS Oh T Akaike CS Cho 2003 A novel degradable polycaprolactone networks for tissue engineering Biomaterials 24 801 808 10.1016/S0142-9612(02)00370-8 (Pubitemid 35449832)
19. R Langer NA Peppas 2003 Advances in biomaterials, drug delivery, and bionanotechnology AIChE J. 49 2990 3006 10.1002/aic.690491202 (Pubitemid 38009884)
20. E.H. Lauten, N.A. Peppas, Selective Recognition of Angiotensin II, in Advances in Medical Engineering, Drug Delivery Systems and Therapeutic Systems, ed. by N.A. Peppas, A.S. Hoffman, T. Kanamori, K. Tojo (AIChE, New York, 2006), pp. 163-166
21. EH Lauten NA Peppas 2009 Intelligent drug release using molecular imprinting methods J. Drug Deliv. Sci. Techn. 19 391 399
22. NV Lavrik MJ Sepaniak PG Datskos 2004 Cantilever transducers as a platform for chemical and biological sensors Rev. Sci. Instrum. 75 2229 2253 10.1063/1.1763252
23. AM Moulin SJ O'Shea ME Welland 2000 Microcantilever-based biosensors Ultramicroscopy 82 23 31 10.1016/S0304-3991(99)00145-X (Pubitemid 30070080)
24. NA Peppas M Byrne E Oral D Henthorn 2001 UV-free radical polymerizations for micropatterning and microimprinting of poly(ethylene glycol)-Containing films Proc. Int. Symp. Polym. Adv. Techn. 6 44
25. NA Peppas JZ Hilt A Khademhosseini R Langer 2006 Hydrogels in biology and medicine: from fundamentals to bionanotechnology Adv. Mater. 18 1345 1360 10.1002/adma.200501612 (Pubitemid 43898575)
26. MA Rice J Sanchez-Adams KS Anseth 2006 Exogenously triggered, enzymatic degradation of photopolymerized hydrogels with polycaprolactone subunits: experimental observation and modeling of mass loss behavior Biomacromolecules 7 1968 1975 10.1021/bm060086+ (Pubitemid 43985121)
27. A Richter G Paschew S Klatt J Lienig K-F Arndt H-J Adler 2008 Review on hydrogel-based pH sensors and microsensors Sensors 8 561 581 10.3390/s8010561
28. Ruzin, Plant Microtechnique and Microscopy (Oxford University Press, 1999)
29. S Timoshenko 1925 Analysis of bimetal thermostats J. Opt. Soc. Am. 11 233 10.1364/JOSA.11.000233
30. I Tokarev S Minko 2008 Stimuli-responsive hydrogel thin film Soft Mater. 5 511 524