Post-natal effect of overexpressed DKK1 on mandibular molar formation

Journal of Dental Research

Volumn 90, Issue 11, 2011, Pages 1312-1317

  Han, X L ^a,b   Liu, M ^c   Voisey, A ^a   Ren, Y S ^a   Kurimoto, P ^c   Gao, T ^a   Tefera, L ^a   Dechow, P ^a   Ke, H Z ^c   Feng, J Q ^a  

^a BAYLOR COLLEGE OF DENTISTRY   (United States)

^b SICHUAN UNIVERSITY   (China)

^c AMGEN INC   (United States)

Author keywords

dentinogenesis; DKK1; mandibular molar; odontoblast; tooth development; transgenic mice

Indexed keywords

DKK1 PROTEIN, MOUSE; INTERMEDIATE FILAMENT PROTEIN; NERVE PROTEIN; NESTIN; OSTERIX PROTEIN, MOUSE; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR; WNT PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CONGENITAL MALFORMATION; DENTIN; GENETICS; GROWTH, DEVELOPMENT AND AGING; MANDIBLE; METABOLISM; MICRO-COMPUTED TOMOGRAPHY; MOLAR TOOTH; MOUSE; ODONTOBLAST; PERIODONTAL LIGAMENT; PHYSIOLOGY; RADIOGRAPHY; SIGNAL TRANSDUCTION; TOOTH DEVELOPMENT; TOOTH MALFORMATION; TOOTH PULP; TRANSGENE; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; DENTAL PULP; DENTIN; DENTINOGENESIS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERMEDIATE FILAMENT PROTEINS; MANDIBLE; MICE; MICE, TRANSGENIC; MOLAR; NERVE TISSUE PROTEINS; ODONTOBLASTS; PERIODONTAL LIGAMENT; SIGNAL TRANSDUCTION; TOOTH ABNORMALITIES; TOOTH CALCIFICATION; TRANSCRIPTION FACTORS; TRANSGENES; UP-REGULATION; WNT PROTEINS; X-RAY MICROTOMOGRAPHY;

EID: 80053645170     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034511421926     Document Type: Article

References (28)

1. Andreasen JO, Andreasen FM. Root resorption following traumatic dental injuries. Proc Finn Dent Soc. 1992 ; 88 (Suppl 1). 95-114
2. Braut A, Kollar EJ, Mina M. Analysis of the odontogenic and osteogenic potentials of dental pulp in vivo using a col1a1-2.3-GFP transgene. Int J Dev Biol. 2003 ; 47: 281-292 (Pubitemid 36604849)
3. Chai Y, Maxson RE. Recent advances in craniofacial morphogenesis. Dev Dyn. 2006 ; 235: 2353-2375 (Pubitemid 44325252)
4. Chen J, Lan Y, Baek JA, Gao Y, Jiang R. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Dev Biol. 2009 ; 334: 174-185
5. DasGupta R, Fuchs E. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development. 1999 ; 126: 4557-4568
6. Denaxa M, Sharpe PT, Pachnis V. The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Dev Biol. 2009 ; 333: 324-336
7. Feng JQ, Ward LM, Liu S, Lu Y, Xie Y, Yuan B, et al. Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet. 2006 ; 38: 1310-1315 (Pubitemid 44646294)
8. Fjeld K, Kettunen P, Furmanek T, Kvinnsland IH, Luukko K. Dynamic expression of Wnt signaling-related Dickkopf1, -2, and -3 mRNAs in the developing mouse tooth. Dev Dyn. 2005 ; 233: 161-166 (Pubitemid 40548035)
9. Fujimori S, Novak H, Weissenbock M, Jussila M, Gonçalves A, Zeller R, et al. Wnt/beta-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol. 2010 ; 348: 97-106
10. Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 1998 ; 391: 357-362 (Pubitemid 28093502)
11. Goldring SR, Goldring MB. Eating bone or adding it: the Wnt pathway decides. Nat Med. 2007 ; 13: 133-134
12. Grotewold L, Ruther U. The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J. 2002 ; 21: 966-975 (Pubitemid 34206169)
13. Grotewold L, Theil T, Ruther U. Expression pattern of Dkk-1 during mouse limb development. Mech Dev. 1999 ; 89: 151-153 (Pubitemid 29528284)
14. Jernvall J, Thesleff I. Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech Dev. 2000 ; 92: 19-29 (Pubitemid 30125959)
15. Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, et al. Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone. 2006 ; 39: 754-766 (Pubitemid 44311706)
16. Liu F, Thirumangalathu S, Gallant NM, Yang SH, Stoick-Cooper CL, Reddy ST, et al. Wnt-beta-catenin signaling initiates taste papilla development. Nat Genet. 2007 ; 39: 106-112 (Pubitemid 46026509)
17. Liu F, Chu EY, Watt B, Zhang Y, Gallant NM, Andl T, et al. Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol. 2008 ; 313: 210-224 (Pubitemid 350298315)
18. Lohi M, Tucker AS, Sharpe PT. Expression of Axin2 indicates a role for canonical Wnt signaling in development of the crown and root during pre- and postnatal tooth development. Dev Dyn. 2010 ; 239: 160-167
19. Lu Y, Ye L, Yu S, Zhang S, Xie Y, McKee MD, et al. Rescue of odontogenesis in Dmp1-deficient mice by targeted re-expression of DMP1 reveals roles for DMP1 in early odontogenesis and dentin apposition in vivo. Dev Biol. 2007 ; 303: 191-201 (Pubitemid 46241097)
20. Miller SC, Omura TH, Smith LJ. Changes in dentin appositional rates during pregnancy and lactation in rats. J Dent Res. 1985 ; 64: 1062-1064
21. Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, Chen L, Tsukui T, Gomer L, et al. Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev Cell. 2001 ; 1: 423-434 (Pubitemid 33586091)
22. Nie X. Dkk1, -2, and -3 expression in mouse craniofacial development. J Mol Histol. 2005 ; 36: 367-372 (Pubitemid 41740148)
23. Struys T, Krage T, Vandenabeele F, Raab WH, Lambrichts I. Immunohistochemical evidence for proteolipid protein and nestin expression in the late bell stage of developing rodent teeth. Arch Oral Biol. 2005 ; 50: 171-174 (Pubitemid 40252935)
24. Suomalainen M, Thesleff I. Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2010 ; 239: 364-372
25. Terling C, Rass A, Mitsiadis TA, Fried K, Lendahl U, Wroblewski J. Expression of the intermediate filament nestin during rodent tooth development. Int J Dev Biol. 1995 ; 39: 947-956 (Pubitemid 26097618)
26. Thomas BL, Tucker AS, Qui M, Ferguson CA, Hardcastle Z, Rubenstein JL, et al. Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition. Development. 1997 ; 124: 4811-4818 (Pubitemid 28014384)
27. Tucker A, Sharpe P. The cutting-edge of mammalian development; how the embryo makes teeth. Nat Rev Genet. 2004 ; 5: 499-508 (Pubitemid 38868506)
28. Williams BO, Insogna KL. Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone. J Bone Miner Res. 2009 ; 24: 171-178