Caucasicosides E-M, furostanol glycosides from Helleborus caucasicus

Phytochemistry

Volumn 72, Issue 17, 2011, Pages 2180-2188

  Muzashvili, Tamar ^a   Perrone, Angela ^b   Napolitano, Assunta ^b   Kemertelidze, Ether ^a   Pizza, Cosimo ^b   Piacente, Sonia ^b  

^a Institute of Pharmacochemistry   (Georgia)

^b UNIVERSITY OF SALERNO   (Italy)

Author keywords

5 Polyhydroxylated steroids; Furostanol glycosides; Helleborus caucasicus; Ranunculaceae

Indexed keywords

BUFADIENOLIDE DERIVATIVE; CAUCASICOSIDE; ECDYSTEROID; GLYCOSIDE; PLANT EXTRACT; STEROL;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT LEAF; VERATRUM;

BUFANOLIDES; ECDYSTEROIDS; GLYCOSIDES; HELLEBORUS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PLANT EXTRACTS; PLANT LEAVES; STEROLS;

HELLEBORUS; RANUNCULACEAE; VERATRUM;

EID: 80053640408     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2011.08.008     Document Type: Article

References (24)

1. 2-26) on the orientation of the 27-methyl group of furostane-type steroidal saponins Magn. Reson. Chem. 42 2004 990 993 (Pubitemid 40012868)
2. S. Akin, and H. Anil A furostanol saponin and phytoecdysteroid from roots of Helleborus orientalis Chem. Nat. Compd. 43 2007 90 92 (Pubitemid 46643541)
3. C. Bassarello, T. Muzashvili, A. Skhirtladze, E. Kemertelidze, C. Pizza, and S. Piacente Steroidal glycosides from the underground parts of Helleborus caucasicus Phytochemistry 69 2008 1227 1233
4. E. Bombardelli, A. Bonati, B. Gabetta, and G. Mustich Glycosides from rhizomes of Ruscus aculeatus. II Fitoterapia 43 1972 3 10
5. R. Gagnidze Vascular plants of Georgia N. Ketskhoveli, A Nomenclatural Checklist 2005 Tbilisi Republic of Georgia 247
6. 13C NMR study of alpha- and beta-anomeric pairs of d-mannopyranosides and l-rhamnopyranosides Tetrahedron 35 1979 1427 1432
7. F. Kerek Boicil, a new and very efficient antialgic, spasmolytic, and blood vessel regulating drug obtained from the plant Helleborus Int. Conf. Chem. Biotechnol. Biol. Act. Nat. Prod. 2 1981 22 37
8. Y. Meng, P. Whiting, V. Sik, H.H. Rees, and L. Dinan Ecdysteroids and bufadienolides from Helleborus torquatus (Ranunculaceae) Phytochemistry 57 2001 401 407 (Pubitemid 32448453)
9. Y. Mimaki, Y. Takaashi, M. Kuroda, Y. Sashida, and T. Nikaido Steroidal saponins from Nolina recurvata stems and their inhibitory activity on cyclic AMP phosphodiesterase Phytochemistry 42 1996 1609 1615 (Pubitemid 27065657)
10. Y. Mimaki, M. Kuroda, A. Kameyama, A. Yokosuka, and Y. Sashida New steroidal constituents of the underground parts of Ruscus aculeatus and their cytostatic activity on HL-60 cells Chem. Pharm. Bull. 46 1998 298 303 (Pubitemid 28124214)
11. Y. Mimaki, Y. Matsuo, K. Watanabe, and H. Sakagami Furostanol glycosides from the rhizomes of Helleborus orientalis J. Nat. Med. 64 2010 452 459
12. T. Muzashvili, A. Skhirtladze, T. Sulakvelidze, M. Benidze, V. Mshviladze, J. Legault, A. Pichette, and E. Kemertelidze Cytotoxic activity of Helleborus caucasicus A Br. Georgia Chem. J. 6 2006 684 685
13. A. Napolitano, T. Muzashvili, A. Perrone, C. Pizza, E. Kemertelidze, and S. Piacente Steroidal glycosides from Ruscus ponticus Phytochemistry 72 2011 651 661
14. W. Oleszek, M. Sitek, A. Stochmal, S. Piacente, C. Pizza, and P. Cheeke Steroidal saponins of Yucca schidigera Roezl J. Agric. Food Chem. 49 2001 4392 4396 (Pubitemid 32896443)
15. A. Perrone, A. Plaza, E. Bloise, P. Nigro, A.I. Hamed, M.A. Belisario, C. Pizza, and S. Piacente Cytotoxic furostanol saponins and a megastigmane glucoside from Tribulus parvispinus J. Nat. Prod. 68 2005 1549 1553 (Pubitemid 41658910)
16. A. Perrone, T. Muzashvili, A. Napolitano, A. Skhirtladze, E. Kemertelidze, C. Pizza, and S. Piacente Steroidal glycosides from the leaves of Ruscus colchicus: isolation and structural elucidation based on a preliminary liquid chromatography-electrospray ionization tandem mass spectrometry profiling Phytochemistry 70 2009 2078 2088
17. S. Rosselli, A. Maggio, M. Bruno, V. Spadaro, C. Formisano, C. Irace, C. Maffettone, and N. Mascolo Furostanol saponins and ecdysones with cytotoxic activity from Helleborus bocconei ssp. intermedius Phytother. Res. 23 2009 1243 1249
18. A. Skhirtladze, A. Plaza, P. Montoro, M. Benidze, E. Kemertelidze, C. Pizza, and S. Piacente Furostanol saponins from Yucca gloriosa L. rhizomes Biochem. Syst. Ecol. 34 2006 809 814 (Pubitemid 44416091)
19. A. Stochmal, A. Perrone, S. Piacente, and W. Oleszek Saponins in aerial parts of Helleborus viridis L Phytochem. Lett. 3 2010 129 132
20. X.W. Wang, Y. Mao, N.-L. Wang, and X.S. Yao A new phloroglucinol diglycoside derivative from Hypericum japonicum Thunb Molecules 13 2008 2796 2803
21. K. Watanabe, Y. Mimaki, H. Sakagami, and Y. Sashida Bufadienolide and spirostanol glycosides from the rhizomes of Helleborus orientalis J. Nat. Prod. 66 2003 236 241 (Pubitemid 36278236)
22. K. Werawattanametin, V. Podimuang, and A. Suksamrarn Ecdysteroids from Vitex glabrata J. Nat. Prod. 49 1986 364 365
23. F.-Y. Yang, Y.-F. Su, Y. Wang, X. Chai, X. Han, Z.-H. Wu, and X.-M. Gao Bufadienolides and phytoecdystones from the rhizomes of Helleborus thibetanus (Ranunculaceae) Biochem. Syst. Ecol. 38 2010 759 763
24. L. Yuan, T.F. Ji, A.G. Wang, J.B. Yang, and Y.L. Su Two new furostanol saponins from the seeds of Allium cepa L Chin. Chem. Lett. 19 2008 461 464