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Volumn 7, Issue 1, 2011, Pages 151-160

Current and emerging therapies for the treatment of myasthenia gravis

Author keywords

Immunosuppression; Myasthenia gravis; Plasmapheresis; Therapy; Thymectomy

Indexed keywords

ACETYLCHOLINESTERASE; ANTISENSE OLIGONUCLEOTIDE; ATROPINE; AUTOANTIBODY; AZATHIOPRINE; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR ANTIBODY; CHOLINESTERASE INHIBITOR; COMPLEMENT INHIBITOR; COMPLEMENTARY RNA; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; EN 101; ETANERCEPT; IMMUNOGLOBULIN; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NEOSTIGMINE; NEOSTIGMINE METHYL SULFATE; PREDNISONE; PYRIDOSTIGMINE; RITUXIMAB; STEROID; TACROLIMUS; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 80053634167     PISSN: 11766328     EISSN: 11782021     Source Type: Journal    
DOI: 10.2147/NDT.S8915     Document Type: Review
Times cited : (72)

References (84)
  • 1
    • 0017171683 scopus 로고
    • Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value
    • Lindstrom JM, Seybold ME, Lennon VA, Whittingham S, Duane DD. Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value. Neurology. 1976;26(11): 1054-1059.
    • (1976) Neurology , vol.26 , Issue.11 , pp. 1054-1059
    • Lindstrom, J.M.1    Seybold, M.E.2    Lennon, V.A.3    Whittingham, S.4    Duane, D.D.5
  • 2
    • 0036779688 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of myasthenia gravis
    • Vincent A. Unravelling the pathogenesis of myasthenia gravis. Nat Rev Immunol. 2002;2(10):797-804.
    • (2002) Nat Rev Immunol , vol.2 , Issue.10 , pp. 797-804
    • Vincent, A.1
  • 3
    • 77955916885 scopus 로고    scopus 로고
    • Development of novel therapies for MG:Studies In Animal Models
    • Souroujon MC, Brenner T, Fuchs S. Development of novel therapies for MG: Studies in animal models. Autoimmunity. 2010;43(5-6): 446-460.
    • (2010) Autoimmunity , vol.43 , Issue.5-6 , pp. 446-460
    • Souroujon, M.C.1    Brenner, T.2    Fuchs, S.3
  • 4
    • 45249113310 scopus 로고    scopus 로고
    • Clinical phenotype of muscle-specific tyrosine kinaseantibody- positive myasthenia gravis
    • Wolfe GI, Oh SJ. Clinical phenotype of muscle-specific tyrosine kinaseantibody- positive myasthenia gravis. Ann N Y Acad Sci. 2008;1132: 71-75.
    • (2008) Ann N Y Acad Sci , vol.1132 , pp. 71-75
    • Wolfe, G.I.1    Oh, S.J.2
  • 5
    • 46849112624 scopus 로고    scopus 로고
    • IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis
    • Leite MI, Jacob S, Viegas S, et al. IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis. Brain. 2008;131(7): 1940-1952.
    • (2008) Brain , vol.131 , Issue.7 , pp. 1940-1952
    • Leite, M.I.1    Jacob, S.2    Viegas, S.3
  • 6
    • 13144277543 scopus 로고    scopus 로고
    • Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis
    • Shiraishi H, Motomura M, Yoshimura T, et al. Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis. Ann Neurol. 2005;57(2):289-293.
    • (2005) Ann Neurol , vol.57 , Issue.2 , pp. 289-293
    • Shiraishi, H.1    Motomura, M.2    Yoshimura, T.3
  • 7
    • 2942620897 scopus 로고    scopus 로고
    • Are MuSK antibodies the primary cause of myasthenic symptoms?
    • Selcen D, Fukuda T, Shen XM, Engel AG. Are MuSK antibodies the primary cause of myasthenic symptoms? Neurology. 2004;62(11): 1945-1950.
    • (2004) Neurology , vol.62 , Issue.11 , pp. 1945-1950
    • Selcen, D.1    Fukuda, T.2    Shen, X.M.3    Engel, A.G.4
  • 8
    • 46749148845 scopus 로고    scopus 로고
    • Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction
    • Cole RN, Reddel SW, Gervásio OL, Phillips WD. Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction. Ann Neurol. 2008;63(6):782-789.
    • (2008) Ann Neurol , vol.63 , Issue.6 , pp. 782-789
    • Cole, R.N.1    Reddel, S.W.2    Gervásio, O.L.3    Phillips, W.D.4
  • 9
    • 0028779203 scopus 로고
    • Myasthenia gravis
    • Drachman DB. Myasthenia gravis. N Engl J Med. 1994;330(25): 1797-1810.
    • (1994) N Engl J Med , vol.330 , Issue.25 , pp. 1797-1810
    • Drachman, D.B.1
  • 10
    • 21244469489 scopus 로고    scopus 로고
    • Increased Toll-like receptor 4 expression in thymus of myasthenic patients with thymitis and thymic involution
    • Bernasconi P, Barberis M, Baggi F, et al. Increased Toll-like receptor 4 expression in thymus of myasthenic patients with thymitis and thymic involution. Am J Pathol. 2005;167(1):129-139.
    • (2005) Am J Pathol , vol.167 , Issue.1 , pp. 129-139
    • Bernasconi, P.1    Barberis, M.2    Baggi, F.3
  • 11
    • 77952920585 scopus 로고    scopus 로고
    • Epstein-Barr virus persistence and reactivation in myasthenia gravis thymus
    • Cavalcante P, Serafini B, Rosicarelli B, et al. Epstein-Barr virus persistence and reactivation in myasthenia gravis thymus. Ann Neurol. 2010; 67(6):726-738.
    • (2010) Ann Neurol , vol.67 , Issue.6 , pp. 726-738
    • Cavalcante, P.1    Serafini, B.2    Rosicarelli, B.3
  • 12
    • 0037168773 scopus 로고    scopus 로고
    • Thymoma in patients with MG: Characteristics and long-term outcome
    • Evoli A, Minisci C, Di Schino C, et al. Thymoma in patients with MG: characteristics and long-term outcome. Neurology. 2002;59(12): 1844-1850.
    • (2002) Neurology , vol.59 , Issue.12 , pp. 1844-1850
    • Evoli, A.1    Minisci, C.2    di Schino, C.3
  • 13
    • 51849100206 scopus 로고    scopus 로고
    • Thymoma-associated myasthenia gravis: Outcome, clinical and pathological correlations in 197 patients on a 20-year experience
    • Maggi L, Andreetta F, Antozzi C, et al. Thymoma-associated myasthenia gravis: outcome, clinical and pathological correlations in 197 patients on a 20-year experience. J Neuroimmunol. 2008;201-202:237-244.
    • (2008) J Neuroimmunol , vol.201-202 , pp. 237-244
    • Maggi, L.1    Andreetta, F.2    Antozzi, C.3
  • 14
    • 0029904769 scopus 로고    scopus 로고
    • Epidemiologic evidence for a changing natural history of myasthenia gravis
    • Phillips LH 2nd, Torner JC. Epidemiologic evidence for a changing natural history of myasthenia gravis. Neurology. 1996;47(5):1233-1238.
    • (1996) Neurology , vol.47 , Issue.5 , pp. 1233-1238
    • Phillips II, L.H.1    Torner, J.C.2
  • 15
    • 0141839026 scopus 로고    scopus 로고
    • The epidemiology of myasthenia gravis
    • Phillips LH 2nd. The epidemiology of myasthenia gravis. Ann N Y Acad Sci. 2003;998:407-412.
    • (2003) Ann N Y Acad Sci , vol.998 , pp. 407-412
    • Phillips II, L.H.1
  • 16
    • 64349115066 scopus 로고    scopus 로고
    • Autoimmune myasthenia gravis: Emerging clinical and biological heterogeneity
    • Meriggioli MN, Sanders DB. Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity. Lancet Neurol. 2009;8(5): 475-490.
    • (2009) Lancet Neurol , vol.8 , Issue.5 , pp. 475-490
    • Meriggioli, M.N.1    Sanders, D.B.2
  • 17
    • 0037465826 scopus 로고    scopus 로고
    • Myasthenia gravis: A higher than expected incidence in the elderly
    • Aragonès JM, Bolíbar I, Bonfill X, et al. Myasthenia gravis: a higher than expected incidence in the elderly. Neurology. 2003;60(6):1024-1026.
    • (2003) Neurology , vol.60 , Issue.6 , pp. 1024-1026
    • Aragonès, J.M.1    Bolíbar, I.2    Bonfill, X.3
  • 18
    • 0042205092 scopus 로고    scopus 로고
    • Evidence of underdiagnosis of myasthenia gravis in older people
    • Vincent A, Clover L, Buckley C, et al. Evidence of underdiagnosis of myasthenia gravis in older people. J Neurol Neurosurg Psychiatry. 2003;74(8):1105-1108.
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , Issue.8 , pp. 1105-1108
    • Vincent, A.1    Clover, L.2    Buckley, C.3
  • 19
    • 45249092352 scopus 로고    scopus 로고
    • Myasthenia gravis in the elderly: Is it different?
    • Aarli JA. Myasthenia gravis in the elderly: Is it different? Ann N Y Acad Sci. 2008;1132:238-243.
    • (2008) Ann N Y Acad Sci , vol.1132 , pp. 238-243
    • Aarli, J.A.1
  • 20
    • 0023696691 scopus 로고
    • Azathioprine as a single drug or in combination with steroids in the treatment of myasthenia gravis
    • Mantegazza R, Antozzi C, Peluchetti D, Sghirlanzoni A, Cornelio F. Azathioprine as a single drug or in combination with steroids in the treatment of myasthenia gravis. J Neurol. 1988;235(8):449-453.
    • (1988) J Neurol , vol.235 , Issue.8 , pp. 449-453
    • Mantegazza, R.1    Antozzi, C.2    Peluchetti, D.3    Sghirlanzoni, A.4    Cornelio, F.5
  • 21
    • 0034641222 scopus 로고    scopus 로고
    • Myasthenia gravis: Recommendations for clinical research standards. Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America
    • Jaretzki A 3rd, Barhon RJ, Ernstoff RM, et al. Myasthenia gravis: recommendations for clinical research standards. Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America. Neurology. 2000;55(1):16-23.
    • (2000) Neurology , vol.55 , Issue.1 , pp. 16-23
    • Jaretzki III, A.1    Barhon, R.J.2    Ernstoff, R.M.3
  • 22
    • 34250337206 scopus 로고    scopus 로고
    • Evidence report: The medical treatment of ocular myasthenia (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology
    • Benathar M, Kaminski HJ. Evidence report: the medical treatment of ocular myasthenia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2007;68(24):2144-2149.
    • (2007) Neurology , vol.68 , Issue.24 , pp. 2144-2149
    • Benathar, M.1    Kaminski, H.J.2
  • 23
    • 33746534220 scopus 로고    scopus 로고
    • Guidelines for the treatment of autoimmune neuromuscular transmission disorders
    • Skeie GO, Apostolski S, Evoli A, et al. Guidelines for the treatment of autoimmune neuromuscular transmission disorders. Eur J Neurol. 2006;13(7):691-699.
    • (2006) Eur J Neurol , vol.13 , Issue.7 , pp. 691-699
    • Skeie, G.O.1    Apostolski, S.2    Evoli, A.3
  • 24
    • 77957813878 scopus 로고    scopus 로고
    • Benefits from sustained-release pyridostigmine bromide in myasthenia gravis: Results of a prospective multicenter open-label trial
    • Sieb JP, Köhler W. Benefits from sustained-release pyridostigmine bromide in myasthenia gravis: results of a prospective multicenter open-label trial. Clin Neurol Neurosurg. 2010;112(9):781-784.
    • (2010) Clin Neurol Neurosurg , vol.112 , Issue.9 , pp. 781-784
    • Sieb, J.P.1    Köhler, W.2
  • 26
    • 0031778585 scopus 로고    scopus 로고
    • Therapy of myasthenic crisis
    • Mayer SA, Thomas CE. Therapy of myasthenic crisis. Crit Care Med. 1998;26(6):1136-1137.
    • (1998) Crit Care Med , vol.26 , Issue.6 , pp. 1136-1137
    • Mayer, S.A.1    Thomas, C.E.2
  • 27
    • 0024387257 scopus 로고
    • The natural course of myasthenia gravis: A long term follow up study
    • Oosterhuis HJ. The natural course of myasthenia gravis: a long term follow up study. J Neurol Neurosurg Psychiatry. 1989;52(10):1121-1127.
    • (1989) J Neurol Neurosurg Psychiatry , vol.52 , Issue.10 , pp. 1121-1127
    • Oosterhuis, H.J.1
  • 28
    • 0006492261 scopus 로고
    • Progress report on mestinon bromide (pyridostigmine bromide)
    • Osserman KE. Progress report on mestinon bromide (pyridostigmine bromide). Am J Med. 1955;19(5):737-739.
    • (1955) Am J Med , vol.19 , Issue.5 , pp. 737-739
    • Osserman, K.E.1
  • 29
    • 0003979209 scopus 로고    scopus 로고
    • Meda Group, Sweden
    • Meda Group, Sweden. (Data on file).
    • Data on File
  • 30
    • 0031024819 scopus 로고    scopus 로고
    • Myasthenia gravis: Diagnosis and follow-up of 100 consecutive patients
    • Beekman R, Kuks JB, Oosterhuis HJ. Myasthenia gravis: diagnosis and follow-up of 100 consecutive patients. J Neurol. 1997;244(2):112-118.
    • (1997) J Neurol , vol.244 , Issue.2 , pp. 112-118
    • Beekman, R.1    Kuks, J.B.2    Oosterhuis, H.J.3
  • 31
    • 39749125211 scopus 로고    scopus 로고
    • Electrophysiological signs and the prevalence of adverse effects of acetylcholinesterase inhibitors in patients with myasthenia gravis
    • Punga AR, Sawada M, Stålberg EV. Electrophysiological signs and the prevalence of adverse effects of acetylcholinesterase inhibitors in patients with myasthenia gravis. Muscle Nerve. 2008;37(3):300-307.
    • (2008) Muscle Nerve , vol.37 , Issue.3 , pp. 300-307
    • Punga, A.R.1    Sawada, M.2    Stålberg, E.V.3
  • 32
    • 0034701812 scopus 로고    scopus 로고
    • A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases
    • Shapira M, Tur-Kaspa I, Bosgraaf L, et al. A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases. Hum Mol Genet. 2000;9(9):1273-128.
    • (2000) Hum Mol Genet , vol.9 , Issue.9 , pp. 1273-1280
    • Shapira, M.1    Tur-Kaspa, I.2    Bosgraaf, L.3
  • 34
    • 29344461548 scopus 로고    scopus 로고
    • Myasthenic crisis
    • Lacomis D. Myasthenic crisis. Neurocrit Care. 2005;3(3):189-194.
    • (2005) Neurocrit Care , vol.3 , Issue.3 , pp. 189-194
    • Lacomis, D.1
  • 35
    • 34548171625 scopus 로고    scopus 로고
    • Myasthenic crisis: Guidelines for prevention and treatment
    • Jani-Acsadi A, Lisak RP. Myasthenic crisis: guidelines for prevention and treatment. J Neurol Sci. 2007;261(1-2):127-133.
    • (2007) J Neurol Sci , vol.261 , Issue.1-2 , pp. 127-133
    • Jani-Acsadi, A.1    Lisak, R.P.2
  • 36
    • 45249105334 scopus 로고    scopus 로고
    • Response to therapy in myasthenia gravis with anti-MuSK antibodies
    • Evoli A, Bianchi MR, Riso R, et al. Response to therapy in myasthenia gravis with anti-MuSK antibodies. Ann N Y Acad Sci. 2008;1132:76-83.
    • (2008) Ann N Y Acad Sci , vol.1132 , pp. 76-83
    • Evoli, A.1    Bianchi, M.R.2    Riso, R.3
  • 37
    • 0242336467 scopus 로고    scopus 로고
    • Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis
    • Evoli A, Tonali PA, Padua L, et al. Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis. Brain. 2003;126(10):2304-2311.
    • (2003) Brain , vol.126 , Issue.10 , pp. 2304-2311
    • Evoli, A.1    Tonali, P.A.2    Padua, L.3
  • 38
    • 33745700892 scopus 로고    scopus 로고
    • Cholinergic neuromuscular hyperactivity in patients with myasthenia gravis seropositive for MuSK antibody
    • Punga AR, Flink R, Askmark H, Stålberg EV. Cholinergic neuromuscular hyperactivity in patients with myasthenia gravis seropositive for MuSK antibody. Muscle Nerve. 2006;34(1):111-115.
    • (2006) Muscle Nerve , vol.34 , Issue.1 , pp. 111-115
    • Punga, A.R.1    Flink, R.2    Askmark, H.3    Stålberg, E.V.4
  • 40
    • 33846170891 scopus 로고    scopus 로고
    • Myasthenia gravis in pregnancy and birth: Identifying risk factors, optimising care
    • Hoff JM, Daltveit AK, Gilhus NE. Myasthenia gravis in pregnancy and birth: identifying risk factors, optimising care. Eur J Neurol. 2007;14(1): 38-43.
    • (2007) Eur J Neurol , vol.14 , Issue.1 , pp. 38-43
    • Hoff, J.M.1    Daltveit, A.K.2    Gilhus, N.E.3
  • 41
    • 0017275912 scopus 로고
    • Glucocorticosteroid therapy: Mechanism of action and clinical consideration
    • Fauci AS, Dale DC, Balow JE. Glucocorticosteroid therapy: mechanism of action and clinical consideration. Ann Intern Med. 1976;84(3): 304-315.
    • (1976) Ann Intern Med , vol.84 , Issue.3 , pp. 304-315
    • Fauci, A.S.1    Dale, D.C.2    Balow, J.E.3
  • 42
    • 0021329141 scopus 로고
    • Long-term corticosteroid treatment of myasthenia gravis: Report of 116 patients
    • Pascuzzi RM, Coslett HB, Johns TR. Long-term corticosteroid treatment of myasthenia gravis: report of 116 patients. Ann Neurol. 1984;15(3): 291-298.
    • (1984) Ann Neurol , vol.15 , Issue.3 , pp. 291-298
    • Pascuzzi, R.M.1    Coslett, H.B.2    Johns, T.R.3
  • 45
    • 68349142911 scopus 로고    scopus 로고
    • Ocular myasthenia gravis: Treatment successes and failures in patients with long-term follow-up
    • Kupersmith MJ. Ocular myasthenia gravis: treatment successes and failures in patients with long-term follow-up. J Neurol. 2009;256(8): 1314-1320.
    • (2009) J Neurol , vol.256 , Issue.8 , pp. 1314-1320
    • Kupersmith, M.J.1
  • 46
    • 0348014427 scopus 로고    scopus 로고
    • Immunotherapy of ocular myasthenia gravis reduces conversion to generalized myasthenia gravis
    • Mee J, Paine M, Byrne E, King J, Reardon K, O'Day J. Immunotherapy of ocular myasthenia gravis reduces conversion to generalized myasthenia gravis. J Neuroophthalmol. 2003;23(4):251-255.
    • (2003) J Neuroophthalmol , vol.23 , Issue.4 , pp. 251-255
    • Mee, J.1    Paine, M.2    Byrne, E.3    King, J.4    Reardon, K.5    O'Day, J.6
  • 48
    • 0031747483 scopus 로고    scopus 로고
    • A randomized double-blind trial of prednisolone alone or with azathioprine in myasthenia gravis
    • Myasthenia Gravis Study Group
    • Palace J, Newsom-Davis J, Lecky B. A randomized double-blind trial of prednisolone alone or with azathioprine in myasthenia gravis. Myasthenia Gravis Study Group. Neurology. 1998;50(6): 1778-1783.
    • (1998) Neurology , vol.50 , Issue.6 , pp. 1778-1783
    • Palace, J.1    Newsom-Davis, J.2    Lecky, B.3
  • 49
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - drug disposition, drug targets, and side effects
    • Evans WE, McLeod HL. Pharmacogenomics - drug disposition, drug targets, and side effects. N Engl J Med. 2003;348(6):538-549.
    • (2003) N Engl J Med , vol.348 , Issue.6 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 50
    • 0023118848 scopus 로고
    • Preliminary results of a double-blind, randomized, placebo-controlled trial of cyclosporine in myasthenia gravis
    • Tindall RS, Rollins JA, Phillips JT, Greenlee RG, Wells L, Belendiuk G. Preliminary results of a double-blind, randomized, placebo-controlled trial of cyclosporine in myasthenia gravis. N Engl J Med. 1987;316(12):719-724.
    • (1987) N Engl J Med , vol.316 , Issue.12 , pp. 719-724
    • Tindall, R.S.1    Rollins, J.A.2    Phillips, J.T.3    Greenlee, R.G.4    Wells, L.5    Belendiuk, G.6
  • 51
    • 45249117038 scopus 로고    scopus 로고
    • Rebooting the immune system with high-dose cyclophosphamide for treatment of refractory myasthenia gravis
    • Drachman DB, Adams RN, Hu R, Johns RJ, Brodsky RA. Rebooting the immune system with high-dose cyclophosphamide for treatment of refractory myasthenia gravis. Ann N Y Acad Sci. 2008;1132:305-314.
    • (2008) Ann N Y Acad Sci , vol.1132 , pp. 305-314
    • Drachman, D.B.1    Adams, R.N.2    Hu, R.3    Johns, R.J.4    Brodsky, R.A.5
  • 52
    • 44249093570 scopus 로고    scopus 로고
    • An international, phase III, randomized trial of mycophenolate mofetil in myasthenia gravis
    • Sanders DB, Hart IK, Mantegazza R, et al. An international, phase III, randomized trial of mycophenolate mofetil in myasthenia gravis. Neurology. 2008;71(6):400-406.
    • (2008) Neurology , vol.71 , Issue.6 , pp. 400-406
    • Sanders, D.B.1    Hart, I.K.2    Mantegazza, R.3
  • 53
    • 49049115186 scopus 로고    scopus 로고
    • A trial of mycophenolate mofetil with prednisone as initial immunotherapy in myasthenia gravis
    • Muscle Study Group
    • Muscle Study Group. A trial of mycophenolate mofetil with prednisone as initial immunotherapy in myasthenia gravis. Neurology. 2008;71(6):394-399.
    • (2008) Neurology , vol.71 , Issue.6 , pp. 394-399
  • 54
    • 0025793409 scopus 로고
    • A short plasma exchange protocol is effective in severe myasthenia gravis
    • Antozzi C, Gemma M, Regi B, et al. A short plasma exchange protocol is effective in severe myasthenia gravis. J Neurol. 1991;238(2): 103-107.
    • (1991) J Neurol , vol.238 , Issue.2 , pp. 103-107
    • Antozzi, C.1    Gemma, M.2    Regi, B.3
  • 56
    • 27744586691 scopus 로고    scopus 로고
    • Treatment of myasthenia gravis exacerbation with intravenous immunoglobulin
    • Gajdos P, Tranchant C, Clair B, et al. Treatment of myasthenia gravis exacerbation with intravenous immunoglobulin. Arch Neurol. 2005;62(11):1689-1693.
    • (2005) Arch Neurol , vol.62 , Issue.11 , pp. 1689-1693
    • Gajdos, P.1    Tranchant, C.2    Clair, B.3
  • 57
    • 34047230056 scopus 로고    scopus 로고
    • IV. immunoglobulin in patients with myasthenia gravis. A randomized controlled trial
    • Zinman L, Ng E, Bril V. IV immunoglobulin in patients with myasthenia gravis. A randomized controlled trial. Neurology. 2007;68(11): 837-841.
    • (2007) Neurology , vol.68 , Issue.11 , pp. 837-841
    • Zinman, L.1    Ng, E.2    Bril, V.3
  • 58
    • 44949201207 scopus 로고    scopus 로고
    • Intravenous immunoglobulin for myasthenia gravis
    • CD002277
    • Gajdos P, Chevret S, et al. Intravenous immunoglobulin for myasthenia gravis. Cochrane Database Syst Rev. 2008;(1):CD002277.
    • (2008) Cochrane Database Syst Rev , Issue.1
    • Gajdos, P.1    Chevret, S.2
  • 59
    • 71549128035 scopus 로고    scopus 로고
    • Consensus statement: The use of intravenous immunoglobulin in the treatment of neuromuscular conditions report of the AANEM ad hoc committee
    • Donofrio PD, Berger A, Brannagan TH 3rd, et al. Consensus statement: the use of intravenous immunoglobulin in the treatment of neuromuscular conditions report of the AANEM ad hoc committee. Muscle Nerve. 2009;40(5):890-900.
    • (2009) Muscle Nerve , vol.40 , Issue.5 , pp. 890-900
    • Donofrio, P.D.1    Berger, A.2    Brannagan III, T.H.3
  • 60
    • 0035028938 scopus 로고    scopus 로고
    • Extracorporeal immunoadsorption with protein A: Technical aspects and clinical results
    • Samuelsson G. Extracorporeal immunoadsorption with protein A: technical aspects and clinical results. J Clin Apher. 2001;16(1):49-52.
    • (2001) J Clin Apher , vol.16 , Issue.1 , pp. 49-52
    • Samuelsson, G.1
  • 61
    • 33645932638 scopus 로고    scopus 로고
    • Therapeutic apheresis. State of the art in the year 2005
    • Bosch T. Therapeutic apheresis. State of the art in the year 2005. Ther Apher Dial. 2005;9(6):459-468.
    • (2005) Ther Apher Dial , vol.9 , Issue.6 , pp. 459-468
    • Bosch, T.1
  • 62
    • 0017151751 scopus 로고
    • The value of thymectomy in myasthenia gravis: A computer-assisted matched study
    • Buckingham JM, Howard FM Jr, Bernatz PE, et al. The value of thymectomy in myasthenia gravis: a computer-assisted matched study. Ann Surg. 1976;184:453-458.
    • (1976) Ann Surg , vol.184 , pp. 453-458
    • Buckingham, J.M.1    Howard Jr., F.M.2    Bernatz, P.E.3
  • 63
    • 0034641233 scopus 로고    scopus 로고
    • Practice parameter: Thymectomy for autoimmune myasthenia gravis (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology
    • Gronseth GS, Barohn RJ. Practice parameter: thymectomy for autoimmune myasthenia gravis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2000;55(1):7-15.
    • (2000) Neurology , vol.55 , Issue.1 , pp. 7-15
    • Gronseth, G.S.1    Barohn, R.J.2
  • 64
    • 20244384530 scopus 로고    scopus 로고
    • Video-assisted thoracoscopic extended thymectomy and extended transsternal thymectomy (T-3b) in non-thymomatous myasthenia gravis patients: Remission after 6 years of follow-up
    • Mantegazza R, Baggi F, Bernasconi P, et al. Video-assisted thoracoscopic extended thymectomy and extended transsternal thymectomy (T-3b) in non-thymomatous myasthenia gravis patients: remission after 6 years of follow-up. J Neurol Sci. 2003;212(1-2):31-36.
    • (2003) J Neurol Sci , vol.212 , Issue.1-2 , pp. 31-36
    • Mantegazza, R.1    Baggi, F.2    Bernasconi, P.3
  • 65
    • 37149025804 scopus 로고    scopus 로고
    • Ocular myasthenia gravis treatment: The case against prednisone therapy and thymectomy
    • Gilbert ME, de Sousa EA, Savino PJ. Ocular myasthenia gravis treatment: the case against prednisone therapy and thymectomy. Arch Neurol. 2007;64(12):1790-1792.
    • (2007) Arch Neurol , vol.64 , Issue.12 , pp. 1790-1792
    • Gilbert, M.E.1    de Sousa, E.A.2    Savino, P.J.3
  • 66
    • 37849020440 scopus 로고    scopus 로고
    • Ocular myasthenia: Diagnostic and treatment recommendations and the evidence base
    • Luchanok U, Kaminski HJ. Ocular myasthenia: diagnostic and treatment recommendations and the evidence base. Curr Opin Neurol. 2008;21(1): 8-15.
    • (2008) Curr Opin Neurol , vol.21 , Issue.1 , pp. 8-15
    • Luchanok, U.1    Kaminski, H.J.2
  • 67
    • 51849141688 scopus 로고    scopus 로고
    • Sustained response to Rituximab in anti-AChR and anti-MuSK positive Myasthenia Gravis patients
    • Illa I, Diaz-Manera J, Rojas-Garcia R, et al. Sustained response to Rituximab in anti-AChR and anti-MuSK positive Myasthenia Gravis patients. J Neuroimmunol. 2008;201-202:90-94.
    • (2008) J Neuroimmunol , vol.201-202 , pp. 90-94
    • Illa, I.1    Diaz-Manera, J.2    Rojas-Garcia, R.3
  • 68
    • 58349108549 scopus 로고    scopus 로고
    • Successful treatment of refractory generalized myasthenia gravis with rituximab
    • Lebrun C, Bourg V, Tieulie N, Thomas P. Successful treatment of refractory generalized myasthenia gravis with rituximab. Eur J Neurol. 2009;16(2):246-250.
    • (2009) Eur J Neurol , vol.16 , Issue.2 , pp. 246-250
    • Lebrun, C.1    Bourg, V.2    Tieulie, N.3    Thomas, P.4
  • 69
    • 68549085230 scopus 로고    scopus 로고
    • Rituximab for the treatment of thymoma-associated and de novo myasthenia gravis: 3 cases and review
    • Nelson RP Jr, Pascuzzi RM, Kessler K, et al. Rituximab for the treatment of thymoma-associated and de novo myasthenia gravis: 3 cases and review. J Clin Neuromuscul Dis. 2009;10(4):170-177.
    • (2009) J Clin Neuromuscul Dis , vol.10 , Issue.4 , pp. 170-177
    • Nelson Jr., R.P.1    Pascuzzi, R.M.2    Kessler, K.3
  • 70
    • 63349091321 scopus 로고    scopus 로고
    • Rituximab for myasthenia gravis: Three case reports and review of the literature
    • Stieglbauer K, Topakian R, Schäffer V, Aichner FT. Rituximab for myasthenia gravis: three case reports and review of the literature. J Neurol Sci. 2009;280(1-2):120-122.
    • (2009) J Neurol Sci , vol.280 , Issue.1-2 , pp. 120-122
    • Stieglbauer, K.1    Topakian, R.2    Schäffer, V.3    Aichner, F.T.4
  • 71
    • 0036145585 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune myasthenia gravis with recombinant human tumor necrosis factor receptor Fc protein
    • Christadoss P, Goluszko E. Treatment of experimental autoimmune myasthenia gravis with recombinant human tumor necrosis factor receptor Fc protein. J Neuroimmunol. 2002;122(1-2):186-190.
    • (2002) J Neuroimmunol , vol.122 , Issue.1-2 , pp. 186-190
    • Christadoss, P.1    Goluszko, E.2
  • 72
    • 11144331435 scopus 로고    scopus 로고
    • Etanercept treatment in corticosteroid-dependent myasthenia gravis
    • Rowin J, Meriggioli MN, Tuzun E, Leurgans S, Christadoss P. Etanercept treatment in corticosteroid-dependent myasthenia gravis. Neurology. 2004;63(12):2390-2392.
    • (2004) Neurology , vol.63 , Issue.12 , pp. 2390-2392
    • Rowin, J.1    Meriggioli, M.N.2    Tuzun, E.3    Leurgans, S.4    Christadoss, P.5
  • 73
    • 17444370887 scopus 로고    scopus 로고
    • Myasthenia gravis patients with low plasma IL-6 and IFN-gamma benefit from etanercept treatment
    • Tuzun E, Meriggioli MN, Rowin J, Yang H, Christadoss P. Myasthenia gravis patients with low plasma IL-6 and IFN-gamma benefit from etanercept treatment. J Autoimmun. 2005;24(3):261-268.
    • (2005) J Autoimmun , vol.24 , Issue.3 , pp. 261-268
    • Tuzun, E.1    Meriggioli, M.N.2    Rowin, J.3    Yang, H.4    Christadoss, P.5
  • 74
    • 45249122485 scopus 로고    scopus 로고
    • Classical complement pathway in experimental autoimmune myasthenia gravis pathogenesis
    • Christadoss P, Tuzun E, Li J, Saini SS, Yang H. Classical complement pathway in experimental autoimmune myasthenia gravis pathogenesis. Ann N Y Acad Sci. 2008;1132:210-219.
    • (2008) Ann N Y Acad Sci , vol.1132 , pp. 210-219
    • Christadoss, P.1    Tuzun, E.2    Li, J.3    Saini, S.S.4    Yang, H.5
  • 75
    • 0032699091 scopus 로고    scopus 로고
    • Oral administration of an immunodominant T-cell epitope downregulates Th1/Th2 cytokines and prevents experimental myasthenia gravis
    • Baggi F, Andreetta F, Caspani E, et al. Oral administration of an immunodominant T-cell epitope downregulates Th1/Th2 cytokines and prevents experimental myasthenia gravis. J Clin Invest. 1999;104(9): 1287-1295.
    • (1999) J Clin Invest , vol.104 , Issue.9 , pp. 1287-1295
    • Baggi, F.1    Andreetta, F.2    Caspani, E.3
  • 76
    • 0034333284 scopus 로고    scopus 로고
    • Mechanism of nasal tolerance induced by a recombinant fragment of acetylcholine receptor for treatment of experimental myasthenia gravis
    • Im SH, Barchan D, Fuchs S, Souroujon MC. Mechanism of nasal tolerance induced by a recombinant fragment of acetylcholine receptor for treatment of experimental myasthenia gravis. J Neuroimmunol. 2000;111(1-2):161-168.
    • (2000) J Neuroimmunol , vol.111 , Issue.1-2 , pp. 161-168
    • Im, S.H.1    Barchan, D.2    Fuchs, S.3    Souroujon, M.C.4
  • 77
    • 34547895887 scopus 로고    scopus 로고
    • Treatment of human myasthenia gravis with oral antisense suppression of acetylcholinesterase
    • Argov Z, McKee D, Agus S, et al. Treatment of human myasthenia gravis with oral antisense suppression of acetylcholinesterase. Neurology. 2007;69(7):699-700.
    • (2007) Neurology , vol.69 , Issue.7 , pp. 699-700
    • Argov, Z.1    McKee, D.2    Agus, S.3
  • 79
    • 0042665907 scopus 로고    scopus 로고
    • Induction of peripheral tolerance to experimental autoimmune myasthenia gravis by acetylcholine receptor-pulsed dendritic cells
    • Xiao BG, Duan RS, Link H, Huang YM. Induction of peripheral tolerance to experimental autoimmune myasthenia gravis by acetylcholine receptor-pulsed dendritic cells. Cell Immunol. 2003;223(1):63-69.
    • (2003) Cell Immunol , vol.223 , Issue.1 , pp. 63-69
    • Xiao, B.G.1    Duan, R.S.2    Link, H.3    Huang, Y.M.4
  • 80
    • 2942592225 scopus 로고    scopus 로고
    • Protective potential of experimental autoimmune myasthenia gravis in Lewis rats by IL-10-modified dendritic cells
    • Duan RS, Adikari SB, Huang YM, Link H, Xiao BG. Protective potential of experimental autoimmune myasthenia gravis in Lewis rats by IL-10-modified dendritic cells. Neurobiol Dis. 2004;16(2):461-467.
    • (2004) Neurobiol Dis , vol.16 , Issue.2 , pp. 461-467
    • Duan, R.S.1    Adikari, S.B.2    Huang, Y.M.3    Link, H.4    Xiao, B.G.5
  • 81
    • 46749120143 scopus 로고    scopus 로고
    • Regulatory T cells induced by GM-CSF suppress ongoing experimental myasthenia gravis
    • Sheng JR, Li LC, Ganesh BB, Prabhakar BS, Meriggioli MN. Regulatory T cells induced by GM-CSF suppress ongoing experimental myasthenia gravis. Clin Immunol. 2008;128(2):172-180.
    • (2008) Clin Immunol , vol.128 , Issue.2 , pp. 172-180
    • Sheng, J.R.1    Li, L.C.2    Ganesh, B.B.3    Prabhakar, B.S.4    Meriggioli, M.N.5
  • 82
    • 45249089477 scopus 로고    scopus 로고
    • Antigen-specific apheresis of pathogenic autoantibodies from myasthenia gravis sera
    • Tzartos S, Bitzopoulou K, Gavra I, et al. Antigen-specific apheresis of pathogenic autoantibodies from myasthenia gravis sera. Ann N Y Acad Sci. 2008;1132:291-299.
    • (2008) Ann N Y Acad Sci , vol.1132 , pp. 291-299
    • Tzartos, S.1    Bitzopoulou, K.2    Gavra, I.3
  • 83
    • 45249113754 scopus 로고    scopus 로고
    • Treatment of myasthenia gravis by preventing acetylcholine receptor modulation
    • Losen M, Martinez-Martinez P, Phernambucq M, et al. Treatment of myasthenia gravis by preventing acetylcholine receptor modulation. Ann N Y Acad Sci. 2008;1132:174-179.
    • (2008) Ann N Y Acad Sci , vol.1132 , pp. 174-179
    • Losen, M.1    Martinez-Martinez, P.2    Phernambucq, M.3
  • 84
    • 34548694517 scopus 로고    scopus 로고
    • Anti- inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange
    • Schuurman J, Losen M, et al. Anti- inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange. Science. 2007;317(5844):1554-1557.
    • (2007) Science , vol.317 , Issue.5844 , pp. 1554-1557
    • Schuurman, J.1    Losen, M.2


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