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Volumn 9, Issue 10, 2011, Pages 909-922

Will new antimicrobials overcome resistance among Gram-negatives?

Author keywords

ESBL; ESCAPE; MBL; new anti Gram negative compounds; new classes of antimicrobials

Indexed keywords

ACHN 490; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AN 3365; AN 3665; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; AVIBACTAM; BAL 30376; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE INHIBITOR; BLI 489; CARBAPENEM DERIVATIVE; CB 182 804; CHIR 090; CLAVULANIC ACID; COLISTIN; EXTENDED SPECTRUM BETA LACTAMASE; KB 001; LK 157; MBX AGENT; ME 1071; METALLO BETA LACTAMASE; MK 7655; MONOBACTAM DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULBACTAM; TAZOBACTAM; TIGECYCLINE; TP 434; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 80053627057     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/eri.11.107     Document Type: Review
Times cited : (45)

References (94)
  • 1
    • 78449246200 scopus 로고    scopus 로고
    • Current epidemiology of multidrug-resistant Gram-negative bacilli in the United States
    • Kallen AJ, Srinivasan A. Current epidemiology of multidrug-resistant Gram-negative bacilli in the United States. Infect. Control Hosp. Epidemiol. 31(Suppl. 1), S51-S54 (2010
    • (2010) Infect. Control Hosp. Epidemiol , vol.31 , Issue.SUPPL. 1
    • Kallen, A.J.1    Srinivasan, A.2
  • 2
    • 58949091766 scopus 로고    scopus 로고
    • Emergence of extensively drug-resistant and pandrug-resistant Gram-negative bacilli in Europe
    • pii
    • Souli M, Galani I, Giamarellou H. Emergence of extensively drug-resistant and pandrug-resistant Gram-negative bacilli in Europe. Euro Surveill. 13, pii: 19045 (2008
    • (2008) Euro Surveill , vol.13 , pp. 19045
    • Souli, M.1    Galani, I.2    Giamarellou, H.3
  • 3
    • 40549101032 scopus 로고    scopus 로고
    • Comparative analysis of antimicrobial susceptibility among organisms from France, Germany, Italy, Spain and the UK as part of the tigecycline evaluation and surveillance trial
    • DOI 10.1111/j.1469-0691.2007.01943.x
    • Rodloff AC, Leclercq R, Debbia EA, Canton R, Oppenheim BA, Dowzicky MJ. Comparative analysis of antimicrobial susceptibility among organisms from France, Germany, Italy, Spain and the UK as part of the tigecycline evaluation and surveillance trial. Clin. Microbiol. Infect. 14(4), 307-314 (2008 (Pubitemid 351356520)
    • (2008) Clinical Microbiology and Infection , vol.14 , Issue.4 , pp. 307-314
    • Rodloff, A.C.1    Leclercq, R.2    Debbia, E.A.3    Canton, R.4    Oppenheim, B.A.5    Dowzicky, M.J.6
  • 4
    • 77954939129 scopus 로고    scopus 로고
    • Recognition and prevention of multidrug-resistant Gram-negative bacteria in the intensive care unit
    • Maragakis LL. Recognition and prevention of multidrug-resistant Gram-negative bacteria in the intensive care unit. Crit. Care Med, 38(Suppl. 8), S345-S351 (2010
    • (2010) Crit. Care Med , vol.38 , Issue.SUPPL. 8
    • Maragakis, L.L.1
  • 5
    • 40549129995 scopus 로고    scopus 로고
    • Bad bugs, no drugs: No ESCAPE revisited. Clin. Infect. Dis. 49(6), 992-993 (2009). 6 Giske CG, Monnet DL, Cars O, Carmeli Y. Clinical and economic impact of common multidrug-resistant Gram-negative bacilli
    • Peterson LR. Bad bugs, no drugs: No ESCAPE revisited. Clin. Infect. Dis. 49(6), 992-993 (2009). 6 Giske CG, Monnet DL, Cars O, Carmeli Y. Clinical and economic impact of common multidrug-resistant Gram-negative bacilli. Antimicrob. Agents Chemother. 52(3), 813-821 (2008
    • (2008) Antimicrob. Agents Chemother , vol.52 , Issue.3 , pp. 813-821
    • Peterson, L.R.1
  • 6
    • 78650339210 scopus 로고    scopus 로고
    • Escherichia coli O25b-ST131: A pandemic, multiresistant, community-associated strain
    • Rogers BA, Sidjabat HE, Paterson DL. Escherichia coli O25b-ST131: A pandemic, multiresistant, community-associated strain. J. Antimicrob. Chemother. 66(1), 1-14 (2010
    • (2010) J. Antimicrob. Chemother , vol.66 , Issue.1 , pp. 1-14
    • Rogers, B.A.1    Sidjabat, H.E.2    Paterson, D.L.3
  • 7
    • 77952504805 scopus 로고    scopus 로고
    • Pharmacodynamic modeling of intravenous antibiotics against Gram-negative bacteria collected in the United States
    • Koomanachai P, Bulik CC, Kuti JL, Nicolau DP. Pharmacodynamic modeling of intravenous antibiotics against Gram-negative bacteria collected in the United States. Clin. Ther. 32(4), 766-779 (2010
    • (2010) Clin. Ther , vol.32 , Issue.4 , pp. 766-779
    • Koomanachai, P.1    Bulik, C.C.2    Kuti, J.L.3    Nicolau, D.P.4
  • 9
    • 77950255824 scopus 로고    scopus 로고
    • The 10 × '20 Initiative: Pursuing a global commitment to develop 10 new antibacterial drugs by 2020
    • Infectious Diseases Society of America
    • Infectious Diseases Society of America. The 10 × '20 Initiative: Pursuing a global commitment to develop 10 new antibacterial drugs by 2020. Clin. Infect. Dis. 50(8), 1081-1083 (2010
    • (2010) Clin. Infect. Dis. , vol.50 , Issue.8 , pp. 1081-1083
  • 10
    • 77955658052 scopus 로고    scopus 로고
    • Horizontal transfer of transposable elements and why it matters for eukaryotic evolution
    • Schaack S, Gilbert C, Feschotte C. Promiscuous DNA: Horizontal transfer of transposable elements and why it matters for eukaryotic evolution. Trends Ecol. Evol. 25(9), 537-546 (2010
    • (2010) Trends Ecol. Evol , vol.25 , Issue.9 , pp. 537-546
    • Schaack, S.1    Gilbert, C.2    Feschotte, C.3    Promiscuous, D.N.A.4
  • 11
    • 72849118806 scopus 로고    scopus 로고
    • The spread of Klebsiella pneumoniae carbapenemases: A tale of strains, plasmids, and transposons
    • Munoz-Price LS, Quinn JP. The spread of Klebsiella pneumoniae carbapenemases: A tale of strains, plasmids, and transposons. Clin. Infect. Dis. 49(11), 1739-1741 (2009
    • (2009) Clin. Infect. Dis , vol.49 , Issue.11 , pp. 1739-1741
    • Munoz-Price, L.S.1    Quinn, J.P.2
  • 12
    • 20444417098 scopus 로고    scopus 로고
    • Evolution of β-lactam biosynthesis genes and recruitment of trans-acting factors
    • DOI 10.1016/j.phytochem.2005.02.030, PII S0031942205001822
    • Brakhage AA, Al-Abdallah Q, Tüncher A, Spröte P. Evolution of b-lactam biosynthesis genes and recruitment of trans-acting factors. Phytochemistry 66(11), 1200-1210 (2005 (Pubitemid 40793874)
    • (2005) Phytochemistry , vol.66 , Issue.11 SPEC. ISS. , pp. 1200-1210
    • Brakhage, A.A.1    Al-Abdallah, Q.2    Tuncher, A.3    Sprote, P.4
  • 13
    • 80053651253 scopus 로고    scopus 로고
    • Extended-spectrum b-lactamases in Gram negative bacteria
    • Rawat D, Nair D. Extended-spectrum b-lactamases in Gram negative bacteria. J. Glob Infect. Dis. 2(3), 263-274 (2010
    • (2010) J. Glob Infect. Dis , vol.2 , Issue.3 , pp. 263-274
    • Rawat, D.1    Nair, D.2
  • 14
    • 78649697323 scopus 로고    scopus 로고
    • Emerging carbapenemases: A global perspective
    • Walsh TR. Emerging carbapenemases: A global perspective. Int. J. Antimicrob. Agents. 36(Suppl. 3), S8-S14 (2010
    • (2010) Int. J. Antimicrob. Agents , vol.36 , Issue.SUPPL. 3
    • Walsh, T.R.1
  • 15
    • 35448972600 scopus 로고    scopus 로고
    • Mortality and delay in effective therapy associated with extended-spectrum β-lactamase production in Enterobacteriaceae bacteraemia: A systematic review and meta-analysis
    • DOI 10.1093/jac/dkm318
    • Schwaber MJ, Carmeli Y. Mortality and delay in effective therapy associated with extended-spectrum b-lactamase production in Enterobacteriaceae bacteraemia: A systematic review and meta-analysis. J. Antimicrob. Chemother. 60(5), 913-920 (2007 (Pubitemid 47617735)
    • (2007) Journal of Antimicrobial Chemotherapy , vol.60 , Issue.5 , pp. 913-920
    • Schwaber, M.J.1    Carmeli, Y.2
  • 16
    • 0029071785 scopus 로고
    • A functional classification scheme for b-lactamases and its correlation with molecular structure
    • Bush K, Jacoby GA, Medeiros AA. A functional classification scheme for b-lactamases and its correlation with molecular structure. Antimicrob. Agents Chemother. 39(6), 1211-1233 (1995
    • (1995) Antimicrob. Agents Chemother , vol.39 , Issue.6 , pp. 1211-1233
    • Bush, K.1    Jacoby, G.A.2    Medeiros, A.A.3
  • 18
    • 77950477270 scopus 로고    scopus 로고
    • Extended-spectrum-b-lactamase AmpC and carbapenemase issues
    • Thomson KS. Extended-spectrum-b-lactamase, AmpC, and carbapenemase issues. J. Clin. Microbiol. 48(4), 1019-1025 (2010
    • (2010) J. Clin. Microbiol. , vol.48 , Issue.4 , pp. 1019-1025
    • Thomson, K.S.1
  • 19
    • 62749195559 scopus 로고    scopus 로고
    • The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
    • Nordmann P, Cuzon G, Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect. Dis. 9(4), 228-236 (2009
    • (2009) Lancet Infect. Dis , vol.9 , Issue.4 , pp. 228-236
    • Nordmann, P.1    Cuzon, G.2    Naas, T.3
  • 20
    • 77955917495 scopus 로고    scopus 로고
    • Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: A molecular, biological, and epidemiological study
    • Kumarasamy KK, Toleman MA, Walsh TR et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: A molecular, biological, and epidemiological study. Lancet Infect. Dis. 10(9), 597-602 (2010
    • (2010) Lancet Infect. Dis , vol.10 , Issue.9 , pp. 597-602
    • Kumarasamy, K.K.1    Toleman, M.A.2    Walsh, T.R.3
  • 21
    • 79952789048 scopus 로고    scopus 로고
    • Does broad-spectrum b-lactam resistance due to NDM-1 herald the end of the antibiotic era for treatment of infections caused by Gram-negative bacteriâ
    • Nordmann P, Poirel L, Toleman MA et al. Does broad-spectrum b-lactam resistance due to NDM-1 herald the end of the antibiotic era for treatment of infections caused by Gram-negative bacteriâJ. Antimicrob. Chemother. 66(4), 689-692 (2011
    • (2011) J. Antimicrob. Chemother , vol.66 , Issue.4 , pp. 689-692
    • Nordmann, P.1    Poirel, L.2    Toleman, M.A.3
  • 22
    • 77957951965 scopus 로고    scopus 로고
    • Resistance to polymyxins: Mechanisms, frequency and treatment options
    • Falagas ME, Rafailidis PI, Matthaiou DK. Resistance to polymyxins: Mechanisms, frequency and treatment options. Drug Resist. Update 13(4-5), 132-138 (2010
    • (2010) Drug Resist. Update , vol.13 , Issue.4-5 , pp. 132-138
    • Falagas, M.E.1    Rafailidis, P.I.2    Matthaiou, D.K.3
  • 24
    • 70449124604 scopus 로고    scopus 로고
    • Antibacterial-resistant Pseudomonas aeruginosa: Clinical impact and complex regulation of chromosomally encoded resistance mechanisms
    • Lister PD, Wolter DJ, Hanson ND. Antibacterial-resistant Pseudomonas aeruginosa: Clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin. Microbiol. Rev. 22(4), 582-610 (2009
    • (2009) Clin. Microbiol. Rev , vol.22 , Issue.4 , pp. 582-610
    • Lister, P.D.1    Wolter, D.J.2    Hanson, N.D.3
  • 25
    • 63349106277 scopus 로고    scopus 로고
    • Tigecycline in the treatment of infections from multi-drug resistant Gram-negative pathogens
    • Poulakou G, Kontopidou FV, Paramythiotou E et al. Tigecycline in the treatment of infections from multi-drug resistant Gram-negative pathogens. J. Infect. 58(4) 273-284 (2009
    • (2009) J. Infect , vol.58 , Issue.4 , pp. 273-284
    • Poulakou, G.1    Kontopidou, F.V.2    Paramythiotou, E.3
  • 26
    • 34249708519 scopus 로고    scopus 로고
    • RamA, a transcriptional regulator, and AcrAB, an RND-type efflux pump, are associated with decreased susceptibility to tigecycline in Enterobacter cloacae
    • DOI 10.1089/mdr.2006.9990
    • Keeney D, Ruzin A, Bradford PA. RamA, a transcriptional regulator, and AcrAB, an RND-type efflux pump, are associated with decreased susceptibility to tigecycline in Enterobacter cloacae. Microb. Drug Resist. 13(1), 1-6 (2007 (Pubitemid 46833752)
    • (2007) Microbial Drug Resistance , vol.13 , Issue.1 , pp. 1-6
    • Keeney, D.1    Ruzin, A.2    Bradford, P.A.3
  • 27
    • 0038121041 scopus 로고    scopus 로고
    • Fluoroquinolones: Action and resistance
    • Drlica K, Malik M. Fluoroquinolones: Action and resistance. Curr. Top. Med. Chem. 3(3), 249-282 (2003
    • (2003) Curr. Top. Med. Chem , vol.3 , Issue.3 , pp. 249-282
    • Drlica, K.1    Malik, M.2
  • 28
    • 36749103255 scopus 로고    scopus 로고
    • Aminoglycosides versus bacteria - A description of the action, resistance mechanism, and nosocomial battleground
    • DOI 10.1007/s11373-007-9194-y
    • Shakil S, Khan R, Zarrilli R, Khan AU. Aminoglycosides versus bacteria-a description of the action, resistance mechanism, and nosocomial battleground. J. Biomed. Sci. 15(1), 5-14 (2008 (Pubitemid 350215830)
    • (2008) Journal of Biomedical Science , vol.15 , Issue.1 , pp. 5-14
    • Shakil, S.1    Khan, R.2    Zarrilli, R.3    Khan, A.U.4
  • 29
    • 77956671881 scopus 로고    scopus 로고
    • New aminoglycoside antibiotics
    • Dozzo P, Moser HE. New aminoglycoside antibiotics. Expert Opin. Ther. Pat. 20(10), 1321-1341 (2008
    • (2008) Expert Opin. Ther. Pat , vol.20 , Issue.10 , pp. 1321-1341
    • Dozzo, P.1    Moser, H.E.2
  • 30
    • 13544252827 scopus 로고    scopus 로고
    • 115 in UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA) is essential for product release
    • DOI 10.1074/jbc.M411325200
    • Eschenburg S, Priestman M, Schonbrunn E. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamineenolpyruvyltransferase (MurA) is essential for product release. J. Biol. Chem. 280(5) 3757-3763 (2005 (Pubitemid 40223844)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.5 , pp. 3757-3763
    • Eschenburg, S.1    Priestman, M.2    Schonbrunn, E.3
  • 31
    • 0034001144 scopus 로고    scopus 로고
    • Characterization of the fomA and fomB gene products from Streptomyces wedmorensis, which confer fosfomycin resistance on Escherichia coli
    • Kobayashi S, Kuzuyama T, Seto H. Characterization of the fomA and fomB gene products from Streptomyces wedmorensis, which confer fosfomycin resistance on Escherichia coli. Antimicrob. Agents Chemother. 44(3), 647-650 (2010
    • (2010) Antimicrob. Agents Chemother , vol.44 , Issue.3 , pp. 647-650
    • Kobayashi, S.1    Kuzuyama, T.2    Seto, H.3
  • 32
    • 40949160541 scopus 로고    scopus 로고
    • Novel β-lactam antibiotics and inhibitor combinations
    • DOI 10.1517/13543784.17.3.285
    • Bassetti M, Righi E, Viscoli C. Novel b-lactam antibiotics and inhibitor combinations. Expert Opin. Investig. Drugs. 17(3), 285-296 (2008 (Pubitemid 351578181)
    • (2008) Expert Opinion on Investigational Drugs , vol.17 , Issue.3 , pp. 285-296
    • Bassetti, M.1    Righi, E.2    Viscoli, C.3
  • 33
    • 39749117473 scopus 로고    scopus 로고
    • A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections
    • DOI 10.1086/526527
    • Noel GJ, Bush K, Bagchi P, Ianus J, Strauss RS. A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections. Clin. Infect. Dis. 46(5), 647-655 (2008 (Pubitemid 351321545)
    • (2008) Clinical Infectious Diseases , vol.46 , Issue.5 , pp. 647-655
    • Noel, G.J.1    Bush, K.2    Bagchi, P.3    Ianus, J.4    Strauss, R.S.5
  • 34
    • 67650450720 scopus 로고    scopus 로고
    • Ceftobiprole: A new broad spectrum cephalosporin
    • El Solh A. Ceftobiprole: A new broad spectrum cephalosporin. Expert Opin. Pharmacother. 10(10), 1675-1686 (2009
    • (2009) Expert Opin. Pharmacother , vol.10 , Issue.10 , pp. 1675-1686
    • El Solh, A.1
  • 35
    • 77951264972 scopus 로고    scopus 로고
    • Ceftaroline for complicated skin and skin-structure infections
    • Nannini EC, Stryjewski ME, Corey GR. Ceftaroline for complicated skin and skin-structure infections. Expert Opin. Pharmacother. 11(7), 1197-1206 (2010
    • (2010) Expert Opin. Pharmacother , vol.11 , Issue.7 , pp. 1197-1206
    • Nannini, E.C.1    Stryjewski, M.E.2    Corey, G.R.3
  • 36
    • 67049086953 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant Gram-negative pathogens, including b-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa
    • Vidaillac C, Leonard SN, Sader HS, Jones RN, Rybak MJ. In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant Gram-negative pathogens, including b-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 53(6), 2360-2366 (2009
    • (2009) Antimicrob. Agents Chemother , vol.53 , Issue.6 , pp. 2360-2366
    • Vidaillac, C.1    Leonard, S.N.2    Sader, H.S.3    Jones, R.N.4    Rybak, M.J.5
  • 37
    • 77955957827 scopus 로고    scopus 로고
    • Integrated analysis of CANVAS 1 and 2: Phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection
    • Corey GR, Wilcox M, Talbot GH et al. Integrated analysis of CANVAS 1 and 2: Phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. Clin. Infect. Dis. 51(6), 641-650 (2010
    • (2010) Clin. Infect. Dis , vol.51 , Issue.6 , pp. 641-650
    • Corey, G.R.1    Wilcox, M.2    Talbot, G.H.3
  • 38
    • 34547841550 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes
    • DOI 10.1093/jac/dkm150
    • Mushtaq S, Warner M, Ge Y, Kaniga K, Livermore DM. In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes. J. Antimicrob. Chemother. 60(2), 300-311 (2007 (Pubitemid 47243878)
    • (2007) Journal of Antimicrobial Chemotherapy , vol.60 , Issue.2 , pp. 300-311
    • Mushtaq, S.1    Warner, M.2    Ge, Y.3    Kaniga, K.4    Livermore, D.M.5
  • 39
    • 79956304769 scopus 로고    scopus 로고
    • In vitro Activity of ceftaroline against Gram-positive and Gram-negative pathogens isolated from patients in Canadian hospitals in 2009
    • Karlowsky JA, Adam HJ, Decorby MR, Lagacé-Wiens PR, Hoban DJ, Zhanel GG. In vitro Activity of ceftaroline against Gram-positive and Gram-negative pathogens isolated from patients in Canadian hospitals in 2009. Antimicrob. Agents Chemother. 55(6), 2837-2846 (2011
    • (2011) Antimicrob. Agents Chemother , vol.55 , Issue.6 , pp. 2837-2846
    • Karlowsky, J.A.1    Adam, H.J.2    Decorby, M.R.3    Lagacé-Wiens, P.R.4    Hoban, D.J.5    Zhanel, G.G.6
  • 40
    • 77149179342 scopus 로고    scopus 로고
    • Activity of a new cephalosporin, CXA-101 (FR264205), against b-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients
    • Moya B, Zamorano L, Juan C, Pérez JL, Ge Y, Oliver A. Activity of a new cephalosporin, CXA-101 (FR264205), against b-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients. Antimicrob. Agents Chemother. 54(3), 1213-1217 (2010
    • (2010) Antimicrob. Agents Chemother , vol.54 , Issue.3 , pp. 1213-1217
    • Moya, B.1    Zamorano, L.2    Juan, C.3    Pérez, J.L.4    Ge, Y.5    Oliver, A.6
  • 42
    • 77955378731 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of CXA-101, a new antipseudomonal cephalosporin, in healthy adult male and female subjects receiving single- and multiple-dose intravenous infusions
    • Ge Y, Whitehouse MJ, Friedland I, Talbot GH. Pharmacokinetics and safety of CXA-101, a new antipseudomonal cephalosporin, in healthy adult male and female subjects receiving single- and multiple-dose intravenous infusions. Antimicrob. Agents Chemother. 54(8), 3427-3431 (2010). 44 Titelman E, Karlsson IM, Ge Y, Giske CG. In vitro activity of CXA-101 plus tazobactam (CXA-201) against CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae. Diagn. Microbiol. Infect. Dis. 70(1), 137-141 (2011
    • (2011) Diagn. Microbiol. Infect. Dis , vol.70 , Issue.1 , pp. 137-141
    • Ge, Y.1    Whitehouse, M.J.2    Friedland, I.3    Talbot, G.H.4
  • 43
    • 80053646031 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement (June 2010 Update) M100-S20-U. CLSI, Wayne, PA, US.A
    • Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement (June 2010 Update) M100-S20-U. CLSI, Wayne, PA, USA (2010
  • 47
    • 73849149415 scopus 로고    scopus 로고
    • Hydrolysis and inhibition profiles of b-lactamases from molecular classes A to D with doripenem, imipenem, and meropenem
    • Queenan AM, Shang W, Flamm R, Bush K. Hydrolysis and inhibition profiles of b-lactamases from molecular classes A to D with doripenem, imipenem, and meropenem. Antimicrob. Agents Chemother. 54(1), 565-569 (2010
    • (2010) Antimicrob. Agents Chemother , vol.54 , Issue.1 , pp. 565-569
    • Queenan, A.M.1    Shang, W.2    Flamm, R.3    Bush, K.4
  • 48
    • 41649099025 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study
    • DOI 10.1097/CCM.0b013e3181691b99, PII 0000324620080400000009
    • Chastre J, Wunderink R, Prokocimer P, Lee M, Kaniga K, Friedland I. Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study. Crit. Care Med. 36(4), 1089-1096 (2008 (Pubitemid 351482655)
    • (2008) Critical Care Medicine , vol.36 , Issue.4 , pp. 1089-1096
    • Chastre, J.1    Wunderink, R.2    Prokocimer, P.3    Lee, M.4    Kaniga, K.5    Friedland, I.6
  • 49
    • 77955547358 scopus 로고    scopus 로고
    • A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections
    • Jia B, Lu P, Huang W et al. A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections. Chemotherapy 56(4), 285-290 (2010
    • (2010) Chemotherapy , vol.56 , Issue.4 , pp. 285-290
    • Jia, B.1    Lu, P.2    Huang, W.3
  • 50
    • 79955913859 scopus 로고    scopus 로고
    • Antibacterial activity of carbapenems against clinical isolates of respiratory bacterial pathogens in the northeastern region of Japan in 2007
    • Gomi K, Fujimura S, Fuse K et al. Antibacterial activity of carbapenems against clinical isolates of respiratory bacterial pathogens in the northeastern region of Japan in 2007. J. Infect. Chemother. 17(2), 200-206 (2011
    • (2011) J. Infect. Chemother , vol.17 , Issue.2 , pp. 200-206
    • Gomi, K.1    Fujimura, S.2    Fuse, K.3
  • 51
    • 77954974510 scopus 로고    scopus 로고
    • Relation between the antimicrobial susceptibility of clinical isolates of Pseudomonas aeruginosa from respiratory specimens and antimicrobial use density (AUD) from 2005 through 2008
    • Fukushima Y, Fukushima F, Kamiya K et al. Relation between the antimicrobial susceptibility of clinical isolates of Pseudomonas aeruginosa from respiratory specimens and antimicrobial use density (AUD) from 2005 through 2008. Intern. Med. 49(14), 1333-1340 (2010
    • (2010) Intern. Med , vol.49 , Issue.14 , pp. 1333-1340
    • Fukushima, Y.1    Fukushima, F.2    Kamiya, K.3
  • 52
    • 34347333405 scopus 로고    scopus 로고
    • Relationship between the usage of carbapenem antibiotics and the incidence of imipenem-resistant Pseudomonas aeruginosa
    • DOI 10.1007/s10156-007-0507-x
    • Fujimura S, Nakano Y, Sato T, Shirahata K, Watanabe A. Relationship between the usage of carbapenem antibiotics and the incidence of imipenem-resistant Pseudomonas aeruginosa. J. Infect. Chemother. 13(3), 147-150 (2007 (Pubitemid 47012495)
    • (2007) Journal of Infection and Chemotherapy , vol.13 , Issue.3 , pp. 147-150
    • Fujimura, S.1    Nakano, Y.2    Sato, T.3    Shirahata, K.4    Watanabe, A.5
  • 53
    • 48749127049 scopus 로고    scopus 로고
    • Potent In vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa
    • Koga T, Masuda N, Kakuta M, Namba E, Sugihara C, Fukuoka T. Potent In vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 52(8), 2849-2854 (2008
    • (2008) Antimicrob. Agents Chemother. , vol.52 , Issue.8 , pp. 2849-2854
    • Koga, T.1    Masuda, N.2    Kakuta, M.3    Namba, E.4    Sugihara, C.5    Fukuoka, T.6
  • 54
    • 67650730262 scopus 로고    scopus 로고
    • Activity of the anti-MRSA carbapenem razupenem (PTZ601) against Enterobacteriaceae with defined resistance mechanisms
    • Livermore DM, Mushtaq S, Warner M. Activity of the anti-MRSA carbapenem razupenem (PTZ601) against Enterobacteriaceae with defined resistance mechanisms. J. Antimicrob. Chemother. 64(2), 330-335 (2009
    • (2009) J. Antimicrob. Chemother , vol.64 , Issue.2 , pp. 330-335
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3
  • 55
    • 0038754804 scopus 로고    scopus 로고
    • Panipenem/betamipron
    • DOI 10.2165/00003495-200363090-00005
    • Goa KL, Noble S. Panipenem/betamipron. Drugs 63(9), 913-925, discussion 926 (2003 (Pubitemid 36543086)
    • (2003) Drugs , vol.63 , Issue.9 , pp. 913-925
    • Goa, K.L.1    Noble, S.2
  • 56
    • 67249143421 scopus 로고    scopus 로고
    • In-vitro activity of panipenem against clinical isolates in 2006. Jpn J. Antibiot. 61(1), 1-17 (2008). 59 Morrissey I, Biek D, Janes R. ME1036, a novel carbapenem, with enhanced activity against clinical isolates causing bacteraemic community-acquired pneumonia
    • Yoshida S, Koga T, Kakuta M et al. In-vitro activity of panipenem against clinical isolates in 2006. Jpn J. Antibiot. 61(1), 1-17 (2008). 59 Morrissey I, Biek D, Janes R. ME1036, a novel carbapenem, with enhanced activity against clinical isolates causing bacteraemic community-acquired pneumonia. J. Antimicrob. Chemother. 64(1), 209-210 (2009
    • (2009) J. Antimicrob. Chemother , vol.64 , Issue.1 , pp. 209-210
    • Yoshida, S.1    Koga, T.2    Kakuta, M.3
  • 58
    • 77952614275 scopus 로고    scopus 로고
    • In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant Gram-negative bacilli
    • Page MG, Dantier C, Desarbre E. In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant Gram-negative bacilli. Antimicrob. Agents Chemother. 54(6), 2291-2302 (2010
    • (2010) Antimicrob. Agents Chemother , vol.54 , Issue.6 , pp. 2291-2302
    • Page, M.G.1    Dantier, C.2    Desarbre, E.3
  • 59
    • 77955560486 scopus 로고    scopus 로고
    • Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens
    • Pfeifer Y, Cullik A, Witte W. Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens. Int. J. Med. Microbiol. 300(6), 371-379 (2010
    • (2010) Int. J. Med. Microbiol , vol.300 , Issue.6 , pp. 371-379
    • Pfeifer, Y.1    Cullik, A.2    Witte, W.3
  • 61
    • 77951060664 scopus 로고    scopus 로고
    • Current challenges in antimicrobial chemotherapy: Focus on b-lactamase inhibition
    • Bebrone C, Lassaux P, Vercheval L et al. Current challenges in antimicrobial chemotherapy: Focus on b-lactamase inhibition. Drugs 70(6), 651-679 (2010
    • (2010) Drugs , vol.70 , Issue.6 , pp. 651-679
    • Bebrone, C.1    Lassaux, P.2    Vercheval, L.3
  • 62
    • 65649086111 scopus 로고    scopus 로고
    • Efficacy of piperacillin combined with the penem b-lactamase inhibitor BLI-489 in murine models of systemic infection
    • Petersen PJ, Jones CH, Venkatesan AM, Bradford PA. Efficacy of piperacillin combined with the penem b-lactamase inhibitor BLI-489 in murine models of systemic infection. Antimicrob. Agents Chemother. 53(4), 1698-1700 (2009
    • (2009) Antimicrob. Agents Chemother , vol.53 , Issue.4 , pp. 1698-1700
    • Petersen, P.J.1    Jones, C.H.2    Venkatesan, A.M.3    Bradford, P.A.4
  • 63
    • 67651180741 scopus 로고    scopus 로고
    • B-lactams and b-lactamase-inhibitors in current- or potential-clinical practice: A comprehensive update
    • Shahid M, Sobia F, Singh A et al. b-lactams and b-lactamase-inhibitors in current- or potential-clinical practice: A comprehensive update. Crit. Rev. Microbiol. 35(2), 81-108 (2009
    • (2009) Crit. Rev. Microbiol , vol.35 , Issue.2 , pp. 81-108
    • Shahid, M.1    Sobia, F.2    Singh, A.3
  • 64
    • 77950236410 scopus 로고    scopus 로고
    • Resistance development profiling of piperacillin in combination with the novel {b}-lactamase inhibitor BLI-489
    • Ruzin A, Petersen PJ, Jones CH. Resistance development profiling of piperacillin in combination with the novel {b}-lactamase inhibitor BLI-489. J. Antimicrob. Chemother. 65(2), 252-257 (2010
    • (2010) J. Antimicrob. Chemother , vol.65 , Issue.2 , pp. 252-257
    • Ruzin, A.1    Petersen, P.J.2    Jones, C.H.3
  • 65
    • 59749085456 scopus 로고    scopus 로고
    • In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {b}-lactamase inhibitor
    • Paukner S, Hesse L, Prezelj A, Solmajer T, Urleb U. In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {b}-lactamase inhibitor. Antimicrob. Agents Chemother. 53(2), 505-511 (2009
    • (2009) Antimicrob. Agents Chemother , vol.53 , Issue.2 , pp. 505-511
    • Paukner, S.1    Hesse, L.2    Prezelj, A.3    Solmajer, T.4    Urleb, U.5
  • 66
    • 0041767488 scopus 로고    scopus 로고
    • In vitro activities of novel oxapenems, alone and in combination with ceftazidime, against gram-positive and gram-negative organisms
    • DOI 10.1128/AAC.47.8.2615-2618.2003
    • Jamieson CE, Lambert PA, Simpson IN. In vitro activities of novel oxapenems, alone and in combination with ceftazidime, against Gram-positive and Gram-negative organisms. Antimicrob. Agents Chemother. 47(8), 2615-2618 (2003 (Pubitemid 36919467)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.8 , pp. 2615-2618
    • Jamieson, C.E.1    Lambert, P.A.2    Simpson, I.N.3
  • 67
    • 7244250112 scopus 로고    scopus 로고
    • Pharmacodynamics of ceftazidime plus the serine β-lactamase inhibitor AM-112 against Escherichia coli containing TEM-1 and CTX-M-1 β-lactamases
    • DOI 10.1128/AAC.48.11.4482-4484.2004
    • Bowker KE, Noel AR, Walsh TR, Rogers CA, MacGowan AP. Pharmacodynamics of ceftazidime plus the serine b-lactamase inhibitor AM-112 against Escherichia coli containing TEM-1 and CTX-M-1 b-lactamases. Antimicrob. Agents Chemother. 48(11), 4482-4484 (2004 (Pubitemid 39434924)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.11 , pp. 4482-4484
    • Bowker, K.E.1    Noel, A.R.2    Walsh, T.R.3    Rogers, C.A.4    MacGowan, A.P.5
  • 68
    • 79955537450 scopus 로고    scopus 로고
    • Activity of NXL104 in combination with b-lactams against genetically characterized Escherichia coli and Klebsiella pneumoniae isolates producing class A extended-spectrum b-lactamases and class C b-lactamases
    • Lagacé-Wiens PR, Tailor F, Simner P et al. Activity of NXL104 in combination with b-lactams against genetically characterized Escherichia coli and Klebsiella pneumoniae isolates producing class A extended-spectrum b-lactamases and class C b-lactamases. Antimicrob. Agents Chemother. 55(5), 2434-2437 (2011
    • (2011) Antimicrob. Agents Chemother , vol.55 , Issue.5 , pp. 2434-2437
    • Lagacé-Wiens, P.R.1    Tailor, F.2    Simner, P.3
  • 69
    • 79952120627 scopus 로고    scopus 로고
    • Activity of a novel combination against multidrug-resistant nonfermenters: Ceftazidime plus NXL104
    • Curcio D. Activity of a novel combination against multidrug-resistant nonfermenters: Ceftazidime plus NXL104. Expert Rev. Anti Infect. Ther. 9(2), 173-176 (2011
    • (2011) Expert Rev. Anti Infect. Ther , vol.9 , Issue.2 , pp. 173-176
    • Curcio, D.1
  • 70
    • 77954197253 scopus 로고    scopus 로고
    • Activity of chequerboard combinations of ceftaroline and NXL104 versus b-lactamase-producing Enterobacteriaceae
    • Mushtaq S, Warner M, Williams G, Critchley I, Livermore DM. Activity of chequerboard combinations of ceftaroline and NXL104 versus b-lactamase-producing Enterobacteriaceae. J. Antimicrob. Chemother. 65(7), 1428-1432 (2010
    • (2010) J. Antimicrob. Chemother , vol.65 , Issue.7 , pp. 1428-1432
    • Mushtaq, S.1    Warner, M.2    Williams, G.3    Critchley, I.4    Livermore, D.M.5
  • 72
    • 80053625043 scopus 로고    scopus 로고
    • Pharmacodynamics of imipenem in combination with MK-7655, a b-lactamase inhibitor, in the neutropenic mouse thigh model
    • Boston, MA, USA, 12-15 September
    • Mavridou E, Melchers R, Van Mil A, Mangin E, Mouton JW. Pharmacodynamics of imipenem in combination with MK-7655, a b-lactamase inhibitor, in the neutropenic mouse thigh model. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, USA, 12-15 September 2010. 76 Hirsch EB, Ledesma KR, Chang KT, Motyl MR, Tam VH. In vitro activity of MK-7655 in combination with imipenem (IPM) against carbapenem resistant Gram-negative bacteria. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, USA, 12-15 September 2010.
    • (2010) 50th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Mavridou, E.1    Melchers, R.2    Van Mil, A.3    Mangin, E.4    Mouton, J.W.5
  • 73
    • 62949166438 scopus 로고    scopus 로고
    • Metallo-b-lactamases in Gram-negative bacteria: Introducing the era of pan-resistancê
    • e1-e7
    • Maltezou HC. Metallo-b-lactamases in Gram-negative bacteria: Introducing the era of pan-resistancê Int. J. Antimicrob. Agents. 33(5), 405, e1-e7 (2009
    • (2009) Int. J. Antimicrob. Agents , vol.33 , Issue.5 , pp. 405
    • Maltezou, H.C.1
  • 74
    • 77957867755 scopus 로고    scopus 로고
    • Activity of BAL30376 (monobactam BAL19764 + BAL29880 + clavulanate) versus Gram-negative bacteria with characterized resistance mechanisms
    • Livermore DM, Mushtaq S, Warner M. Activity of BAL30376 (monobactam BAL19764 + BAL29880 + clavulanate) versus Gram-negative bacteria with characterized resistance mechanisms. J. Antimicrob. Chemother. 65(11), 2382-2395 (2010
    • (2010) J. Antimicrob. Chemother , vol.65 , Issue.11 , pp. 2382-2395
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3
  • 75
    • 79953187968 scopus 로고    scopus 로고
    • In vitro and in vivo properties of BAL30376, a b-lactam and dual b-lactamase inhibitor combination with enhanced activity against Gram-negative bacilli that express multiple b-lactamases
    • Page MG, Dantier C, Desarbre E, Gaucher B, Gebhardt K, Schmitt-Hoffmann A. In vitro and in vivo properties of BAL30376, a b-lactam and dual b-lactamase inhibitor combination with enhanced activity against Gram-negative bacilli that express multiple b-lactamases. Antimicrob. Agents Chemother. 55(4), 1510-1519 (2011
    • (2011) Antimicrob. Agents Chemother , vol.55 , Issue.4 , pp. 1510-1519
    • Page, M.G.1    Dantier, C.2    Desarbre, E.3    Gaucher, B.4    Gebhardt, K.5    Schmitt-Hoffmann, A.6
  • 76
    • 77956116298 scopus 로고    scopus 로고
    • In vitro potentiation of carbapenems with ME1071, a novel metallo-b-lactamase inhibitor, against metallo-b-lactamase- producing Pseudomonas aeruginosa clinical isolates
    • Ishii Y, Eto M, Mano Y, Tateda K, Yamaguchi K. In vitro potentiation of carbapenems with ME1071, a novel metallo-b-lactamase inhibitor, against metallo-b-lactamase- producing Pseudomonas aeruginosa clinical isolates. Antimicrob. Agents Chemother. 54(9), 3625-3629 (2010
    • (2010) Antimicrob. Agents Chemother , vol.54 , Issue.9 , pp. 3625-3629
    • Ishii, Y.1    Eto, M.2    Mano, Y.3    Tateda, K.4    Yamaguchi, K.5
  • 78
    • 78449259782 scopus 로고    scopus 로고
    • The antibiotic development pipeline for multidrug-resistant Gram-negative bacilli: Current and future landscapes
    • Talbot GH. The antibiotic development pipeline for multidrug-resistant Gram-negative bacilli: Current and future landscapes. Infect. Control Hosp. Epidemiol. 31(Suppl. 1), S55-S58 (2010
    • (2010) Infect. Control Hosp. Epidemiol , vol.31 , Issue.SUPPL. 1
    • Talbot, G.H.1
  • 79
    • 78650378928 scopus 로고    scopus 로고
    • Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates
    • Livermore DM, Mushtaq S, Warner M et al. Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates. J. Antimicrob. Chemother. 66(1), 48-53 (2011
    • (2011) J. Antimicrob. Chemother , vol.66 , Issue.1 , pp. 48-53
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3
  • 80
    • 78651462031 scopus 로고    scopus 로고
    • Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York City
    • Landman D, Kelly P, Bäcker M et al. Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York City. J. Antimicrob. Chemother. 66(2), 332-334 (2011
    • (2011) J. Antimicrob. Chemother , vol.66 , Issue.2 , pp. 332-334
    • Landman, D.1    Kelly, P.2    Bäcker, M.3
  • 81
    • 77957226307 scopus 로고    scopus 로고
    • Activity of a novel aminoglycoside, ACHN-490, against clinical isolates of Escherichia coli and Klebsiella pneumoniae from New York City
    • Landman D, Babu E, Shah N et al. Activity of a novel aminoglycoside, ACHN-490, against clinical isolates of Escherichia coli and Klebsiella pneumoniae from New York City. J. Antimicrob. Chemother. 65(10), 2123-2127 (2011
    • (2011) J. Antimicrob. Chemother , vol.65 , Issue.10 , pp. 2123-2127
    • Landman, D.1    Babu, E.2    Shah, N.3
  • 82
    • 80053626408 scopus 로고    scopus 로고
    • Antimicrobial activity of a novel polymyxin analog (CB-182,804) tested against clinical strains of Gram-negative bacilli, including colistin-resistant organisms. Presented at
    • Boston, MA, USA, 12-15 September
    • Sader HS, Rhomberg PR, Jones RN. Antimicrobial activity of a novel polymyxin analog (CB-182,804) tested against clinical strains of Gram-negative bacilli, including colistin-resistant organisms. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, USA, 12-15 September 2010.
    • (2010) 50th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Sader, H.S.1    Rhomberg, P.R.2    Jones, R.N.3
  • 84
    • 77956120372 scopus 로고    scopus 로고
    • Comparative in vitro activity profiles of novel bis-indole antibacterials against Gram-positive and Gram-negative clinical isolates
    • Butler MM, Williams JD, Peet NP et al. Comparative in vitro activity profiles of novel bis-indole antibacterials against Gram-positive and Gram-negative clinical isolates. Antimicrob. Agents Chemother. 54(9), 3974-3977 (2010
    • (2010) Antimicrob. Agents Chemother , vol.54 , Issue.9 , pp. 3974-3977
    • Butler, M.M.1    Williams, J.D.2    Peet, N.P.3
  • 85
    • 80052404437 scopus 로고    scopus 로고
    • Discovery and mechanism of action of AN3365: A novel boron containing antibacterial agent in clinical development for Gram-negative infections. Presented at
    • Boston, MA, USA, 12-15 September
    • Hernandez V, Akama T, Alley M et al. Discovery and mechanism of action of AN3365: A novel boron containing antibacterial agent in clinical development for Gram-negative infections. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, USA, 12-15 September 2010.
    • (2010) 50th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Hernandez, V.1    Akama, T.2    Alley, M.3
  • 86
    • 80053623498 scopus 로고    scopus 로고
    • Potency and spectrum of activity of AN3365, a novel boron-containing protein synthesis inhibitor, tested against non-fermentative Gram-negative bacilli. Presented at
    • Boston, MA, USA, 12-15 September
    • Biedenbach DJ, Mendes RE, Alley MRK, Sader HS, Jones R. Potency and spectrum of activity of AN3365, a novel boron-containing protein synthesis inhibitor, tested against non-fermentative Gram-negative bacilli. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, USA, 12-15 September 2010.
    • (2010) 50th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Biedenbach, D.J.1    Mendes, R.E.2    Alley, M.R.K.3    Sader, H.S.4    Jones, R.5
  • 87
    • 80053634925 scopus 로고    scopus 로고
    • In vitro activities of AN3365: A novel boron containing protein synthesis inhibitor and other antimicrobial agents against anaerobes and Neisseria gonorrhoeae. Presented at
    • Boston, MA, USA, 12-15 September
    • Bouchillon S, Hoban D, Hackel M, Butler D, Demarsch P, Alley D. In vitro activities of AN3365: A novel boron containing protein synthesis inhibitor and other antimicrobial agents against anaerobes and Neisseria gonorrhoeae. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, USA, 12-15 September 2010.
    • (2010) 50th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Bouchillon, S.1    Hoban, D.2    Hackel, M.3    Butler, D.4    Demarsch, P.5    Alley, D.6
  • 88
    • 80053623890 scopus 로고    scopus 로고
    • Murine pharmacokinetics and in vivo Gram-negative activity of AN3365: A novel boron-containing protein synthesis inhibitor. Presented at
    • Boston, MA, USA, 12-15 September
    • Freund YR, Liu L, Alley MRK et al. Murine pharmacokinetics and in vivo Gram-negative activity of AN3365: A novel boron-containing protein synthesis inhibitor. Presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, USA, 12-15 September 2010.
    • (2010) 50th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Freund, Y.R.1    Liu, L.2    Alley, M.R.K.3
  • 89
    • 79851511830 scopus 로고    scopus 로고
    • Design and synthesis of potent Gram-negative specific LpxC inhibitors
    • Mansoor UF, Vitharana D. Reddy PA et al. Design and synthesis of potent Gram-negative specific LpxC inhibitors. Bioorg Med. Chem. Lett. 21(4), 1155-1161 (2011
    • (2011) Bioorg Med. Chem. Lett , vol.21 , Issue.4 , pp. 1155-1161
    • Mansoor, U.F.1    Vitharana, D.2    Reddy, P.A.3
  • 91
    • 78449236736 scopus 로고    scopus 로고
    • Antimicrobial peptides: Primeval molecules or future drugŝ
    • Peters BM, Shirtliff ME, Jabra-Rizk MA. Antimicrobial peptides: Primeval molecules or future drugŝ PloS Pathog. 6(10), e1001067 (2010
    • (2010) PloS Pathog , vol.6 , Issue.10
    • Peters, B.M.1    Shirtliff, M.E.2    Jabra-Rizk, M.A.3
  • 93
    • 62449123361 scopus 로고    scopus 로고
    • An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity
    • Baer M, Sawa T, Flynn P et al. An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity. Infect. Immun. 77(3), 1083-1090 (2009
    • (2009) Infect. Immun , vol.77 , Issue.3 , pp. 1083-1090
    • Baer, M.1    Sawa, T.2    Flynn, P.3
  • 94
    • 70349420962 scopus 로고    scopus 로고
    • Prospects for the next anti-Pseudomonas drug
    • Page MG, Heim J. Prospects for the next anti-Pseudomonas drug. Curr. Opin. Pharmacol. 9(5), 558-565 (2009).
    • (2009) Curr. Opin. Pharmacol , vol.9 , Issue.5 , pp. 558-565
    • Page, M.G.1    Heim, J.2


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