Exploring the relationship between personality and regional brain volume in healthy aging

Neurobiology of Aging

Volumn 32, Issue 12, 2011, Pages 2162-2171

  Jackson, Jonathan ^a   Balota, David A ^a   Head, Denise ^a,b  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amygdala; Atrophy; Conscientiousness; Extraversion; Hippocampus; Neuroticism; Prefrontal cortex; Volumetry

Indexed keywords

ADULT; AGED; AGING; ARTICLE; BRAIN SIZE; CONSCIENTIOUSNESS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; EXPLORATORY RESEARCH; EXTRAVERSION; FEMALE; GRAY MATTER; HUMAN; MALE; NEUROANATOMY; NEUROSIS; PERSONALITY; PREFRONTAL CORTEX; PRIORITY JOURNAL; TEMPORAL CORTEX; VOLUMETRY; WHITE MATTER;

ADULT; AGED; AGED, 80 AND OVER; AGING; BRAIN; BRAIN MAPPING; CEREBRAL CORTEX; CROSS-SECTIONAL STUDIES; FEMALE; HEALTH STATUS; HUMANS; MALE; MIDDLE AGED; NERVE FIBERS, MYELINATED; ORGAN SIZE; PERSONALITY;

EID: 80053623073     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2009.12.009     Document Type: Article

References (59)

1. Andrews-Hanna J.R., Snyder A.Z., Vincent J.L., Lustig C., Head D., Raichle M.E., Buckner R.L. Disruption of large-scale brain systems in advanced aging. Neuron 2007, 56:924-935.
2. Balota D.A., Dolan P.O., Duchek J.M. Memory changes in healthy older adults. The Oxford Handbook of Memory 2000, 395-409. Oxford University Press, New York. E. Tulving, F.I.M. Craik (Eds.).
3. Balsis S., Carpenter B.D., Storandt M. Personality change precedes clinical diagnosis of dementia of the Alzheimer's type. J. Gerontol. B-Psychol. 2005, 60B:98-101.
4. Berg L. Clinical Dementia Rating (CDR). Psychopharmacol. Bull. 1988, 24:637-639.
5. Bogg T., Roberts B.W. Conscientiousness and health-related behaviors: a meta-analysis of the leading behavioral contributors to mortality. Psychol. Bull. 2004, 130:887-919.
6. Buckner R.L., Head D., Parker J., Fotenos A.F., Marcus D., Morris J.C., Snyder A.Z. A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume. NeuroImage 2004, 23:724-738.
7. Bugg, J.M., Head, D., 2009. Exercise moderates age-related atrophy of the medial temporal lobe. Neurobiol. Aging, doi:10.1016/j.neurobiolaging.2009.03.008.
8. Colcombe S.J., Erickson K.I., Raz N., Webb A.G., Cohen N.J., McAuley E., Kramer A. Aerobic fitness reduces brain tissue loss in aging humans. J. Gerontol. A-Biol. 2003, 58A:176-180.
9. Colcombe S.J., Kramer A.F., Erickson K.I., Scalf P. The implications of cortical recruitment and brain morphology for individual differences in inhibitory function in aging humans. Psychol. Aging 2005, 20:363-375.
10. Colcombe S.J., Erickson K.I., Scalf P.E., Kim J.S., Prakash R., McAuley E., Elavsky S., Marquez D.X., Hu L., Kramer A.F. Aerobic exercise training increases brain volume in aging humans. J. Gerontol. A-Biol. 2006, 61A:1166-1170.
11. Costa P.T., McCrae R.R. Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) Professional Manual 1992, Psychological Assessment Resources, Odessa, FL.
12. Desikan R.S., Ségonne F., Fischl B., Quinn B.T., Dickerson B.C., Blacker D., Buckner R.L., Dale A.M., Maguire R.P., Hyman B.T., Albert M.S., Killiany R.J. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. NeuroImage 2006, 31:968-980.
13. Duchek J.M., Balota D.A., Storandt M., Larsen R. The power of personality in discriminating between healthy aging and early-stage Alzheimer's disease. J. Gerontol. B-Psychol. 2007, 62B:353-361.
14. Erickson K.I., Suever B.L., Prakash R.S., Colcombe S.J., McAuley E., Kramer A.F. Greater intake of vitamins B6 and B12 spares gray matter in healthy elderly: a voxel-based morphometry study. Brain Res. 2008, 1199:20-26.
15. Fischl B., Salat D.H., Busa E., Albert M., Dieterich M., Haselgrove C., van der Kouwe A., Killiany R., Kennedy D., Klaveness S., Montillo A., Makris N., Rosen B., Dale A.M. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 2002, 33:341-355.
16. Fischl B.A., van der Kouwe A., Destrieux C., Halgren E., Segonne F., Salat D., Busa E., Seidman L., Goldstein J., Kennedy D., Caviness V., Makris N., Rosen B., Dale A.M. Automatically parcellating the human cerebral cortex. Cereb. Cortex 2004, 14:11-22.
17. Fotenos A.F., Snyder A.Z., Girton L.E., Morris J.C., Buckner R.L. Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD. Neurology 2005, 64:1032-1039.
18. Gray J.R., Braver T.S. Personality predicts working-memory-related activation in the caudal anterior cingulate cortex. Cogn. Affect. Behav. Neurosci. 2002, 2:64-75.
19. Gray J.R., Burgess G.C., Schaeffer A., Yarkoni T., Larsen R.J., Braver T.S. Affective personality differences in neural processing efficiency confirmed using fMRI. Cogn. Affect. Behav. Neurosci. 2005, 5:182-190.
20. Griffin P.W., Mroczek D.K., Spiro A. Variability in affective change among aging men: longitudinal findings from the VA Normative Aging Study. J. Res. Person. 2006, 40:942-965.
21. Gunning-Dixon F.M., Brickman A.M., Cheng J.C., Alexopoulos G.S. Aging of cerebral white matter: a review of MRI findings. Int. J. Geriatr. Psychiatry 2009, 24:109-117.
22. Gunning-Dixon F.M., Hoptman M.J., Lim K.O., Murphy C.F., Klimstra S., Latoussakis V., Majcher-Tascio M., Hrabe J., Ardekani B.A., Alexopoulos G.S. Macromolecular white matter abnormalities in geriatric depression: a magnetization transfer imaging study. Am J Geriatr Psychiatry 2008, 16:255-262.
23. Hasher L., Zacks R.T. Working memory, comprehension, and aging: a review and a new view. The Psychology of Learning and Motivation 1988, 193-225. Academic Press, New York. G. Bower (Ed.).
24. Head D., Snyder A.Z., Girton L.E., Morris J.C., Buckner R.L. Frontal-hippocampal double dissociation between normal aging and Alzheimer's disease. Cereb. Cortex 2005, 15:732-739.
25. Hedden T., Gabrieli J.D.E. Insights into the ageing mind: a view from cognitive neuroscience. Nat. Rev. Neurosci. 2004, 5:87-96.
26. Hertzog C., Kramer A.F., Wilson R.S., Lindenberger U. Enrichment effects on adult cognitive development: can the functional capacity of older adults be preserved and enhanced?. Psychol. Sci. Public Interest 2009, 9:1-65.
27. Hollingshead, A.B., 1975. Four factor index of social status. Unpublished manuscript.
28. Kang J., Cirrito J.R., Dong H., Csernansky J.G., Holtzman D.M. Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal activity. Proc. Natl. Acad. Sci.-Biol. 2007, 104:10673-10678.
29. Knutson B., Momenan R., Rawlings R.R., Fong G.W., Hommer D. Negative association of neuroticism with brain volume ratio in healthy humans. Biol. Psychiatry 2001, 50:685-690.
30. Lattin J.M., Carroll J.D., Green P.E. Analyzing Multivariate Data 2003, Brooks Cole, Pacific Grove, CA.
31. MacLullich A.M.J., Deary I.J., Starr J.M., Ferguson K.J., Wardlaw J.M., Seckl J.R. Plasma cortisol levels, brain volumes and cognition in healthy elderly men. Psychoneuroendocrinology 2005, 30:505-515.
32. McCrae R.R., Costa P.T. Emerging Lives, Enduring Dispositions: Personality in Adulthood 1984, Little, Brown and Co., Boston.
33. McEwen B.S. Sex, stress, and the hippocampus: allostasis, allostatic load and the aging process. Neurobiol. Aging 2002, 23:921-939.
34. Morris J.C. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993, 43:2412-2414.
35. Mugler J.P., Brookeman J.R. Rapid three-dimensional T1-weighted MR imaging with the MP-RAGE sequence. JMRI-J. Magn. Reson. Imaging 1991, 1:561-567.
36. Neary D., Snowden J.S., Gustafson L., Passant U., Stuss D., Black S., Freedman M., Kertesz A., Robert P.H., Albert M., Boone K., Miller B.L., Cummings J., Benson D.F. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998, 51:1546-1554.
37. Omura K., Todd Constable R., Canli T. Amygdala gray matter concentration is associated extraversion and neuroticism. Neuroreport 2005, 16:1905-1908.
38. Pearman A., Storandt M. Predictors of subjective memory in older adults. J. Gerontol. B-Psychol. 2004, 59B:4-6.
39. Poeggel G., Helmeke C., Abraham A., Schwabe T., Friedrich P., Braun K. Juvenile emotional experience alters synaptic composition in the rodent cortex, hippocampus, and lateral amygdala. Proc. Natl. Acad. Sci.-Biol. 2003, 100:16137-16142.
40. Radley J.J., Morrison J.H. Repeated stress and structural plasticity in the brain. Age. Res. Rev. 2005, 4:271-287.
41. Rankin K.P., Kramer J.H., Mychack P., Miller B.L. Double dissociation of social functioning in frontotemporal dementia. Neurology 2003, 60:266-271.
42. Rauch S.L., Milad M.R., Orr S.P., Quinn B.T., Fischl B., Pitman R.K. Orbitofrontal thickness, retention of fear extinction, and extraversion. Neuroreport 2005, 16:1909-1912.
43. Raz N. The aging brain: structural changes and their implications for cognitive aging. New Frontiers in Cognitive Aging 2004, 115-130. Oxford University Press, New York. R.A. Dixon, L. Backman, L.G. Nilsson (Eds.).
44. Raz N., Rodrigue K.M. Differential aging of the brain: patterns, cognitive correlates and modifiers. Neurosci. Biobehav. Rev. 2006, 30:730-748.
45. Rhodes R.E., Smith N.E.I. Personality correlates of physical activity: a review and meta-analysis. Br. J. Sports Med. 2006, 40:958-965.
46. Robinson M.D., Tamir M. Neuroticism as mental noise: a relation between neuroticism and reaction time standard deviations. J Pers Soc Psychol. 2005, 89:107-114.
47. Sandi C., Pinelo-Nava M.T. Stress and memory: behavioral effects and neurobiological mechanisms. Neural Plast. 2007, 2007:1-20.
48. Sapolsky R.M. Glucocorticoid toxicity in the hippocampus: reversal by supplementation with brain fuels. J. Neurosci. 1986, 6:2240-2244.
49. Stern Y. Cognitive reserve. Neuropsychologia 2009, 47:2015-2028.
50. Talairach J., Tournoux P. Co-planar stereotaxic atlas of the human brain 1988, Thieme Medical Publishers, Inc., New York.
51. Tisserand D.J., Jolles J. Special issue on the involvement of prefrontal networks in cognitive ageing. Cortex 2003, 39:1107-1128.
52. Whittle S., Yücel M., Fornito A., Barrett A., Wood S.J., Lubman D.I., Simmons J., Pantelis C.P., Allen N.B. Neuroanatomical correlates of temperament in early adolescents. J. Am. Acad. Child Psychiatry 2008, 47:682-693.
53. Wilson R.S., Arnold S.E., Schneider J.A., Li Y., Bennett D.A. Chronic distress, age-related neuropathology, and late-life dementia. Psychosom. Med. 2007, 69:47-53.
54. Wilson R.S., Evans D.A., Bienias J.L., Mendes de Leon C.F., Schneider J.A., Bennett D.A. Proneness to psychological distress is associated with risk of Alzheimer's disease. Neurology 2003, 61:1479-1485.
55. Wilson R.S., Schneider J.A., Arnold S.E., Bienas J.L., Bennett D.A. conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment. Arch. Gen. Psychiatry 2007, 64:1204-1212.
56. Wilson R.S., Schneider J.A., Boyle P.A., Arnold S.E., Tang Y., Bennett D.A. Chronic distress and the incidence of mild cognitive impairment. Neurology 2007, 68:2085-2092.
57. Wright C.I., Williams D., Feczko E., Feldman Barrett L., Dickerson B.C., Schwartz C.E., Wedig M.M. Neuroanatomical correlates of extraversion and neuroticism. Cereb. Cortex 2006, 16:1809-1819.
58. Wright C.I., Feczko E., Dickerson B., Williams D. Neuroanatomical correlates of personality in the elderly. NeuroImage 2007, 35:263-272.
59. Yehuda R., Golier J.A., Tischler L., Harvey P.D., Newmark R., Yang R., Buchsbaum M.S. Hippocampal volume in aging combat veterans with and without post-traumatic stress disorder: relation to risk and resilience factors. J. Psychiat. Res. 2007, 41:435-445.