Amygdala gray matter concentration is associated with extraversion and neuroticism

NeuroReport

Volumn 16, Issue 17, 2005, Pages 1905-1908

  Omura, Kazufumi ^a   Constable, R Todd ^b   Canli, Turhan ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

Amygdala; Extraversion; Gray matter concentration; Neuroticism; Voxel based morphometry

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BRAIN REGION; BRAIN SIZE; CENTRAL GRAY MATTER; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; EXTRAVERSION; FEMALE; GRAY MATTER; HUMAN; LEFT HEMISPHERE; MALE; MORPHOMETRICS; NEUROIMAGING; NEUROSIS; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERSONALITY; PRIORITY JOURNAL; RIGHT HEMISPHERE; RISK FACTOR;

ADULT; AMYGDALA; EXTRAVERSION (PSYCHOLOGY); FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROTIC DISORDERS;

EID: 27844568539     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wnr.0000186596.64458.76     Document Type: Article

References (22)

1. Canli T. Functional brain mapping of extra version and neuroticism: learning from individual differences in emotion processing. J Pers 2004; 72:1105-1132.
2. Canli T, Zhao Z, Desmond JE, Kang E, Gross J, Gabrieli JDE. An fMRI study of personality influences on brain reactivity to emotional stimuli. Behav Neurosci 2001; 115:33-42.
3. Matsui M, Yoneyama E, Sumiyoshi T, Noguchi K, Nohara S, Suzuki M, et al. Lack of self-control as assessed by a personality inventory is related to reduced volume of supplementary motor area. Psychiatry Res 2002; 116:53-61.
4. Knutson B, Momenan R, Rawlings RR, Fong GW, Hommer D. Negative association of neuroticism with brain volume ratio in healthy humans. Biol Psychiatry 2001; 50:685-690.
5. Onitsuka T, Nestor PG, Gurrera RJ, Shenton ME, Kasai K, Frumin M, et al. Association between reduced extraversion and right posterior fusiform gyrus gray matter reduction in chronic schizophrenia. Am J Psychiatry 2005; 162:599-601.
6. Canli T, Sivers H, Whitfield SL, Gotlib IH, Gabrieli JD. Amygdala response to happy faces as a function of extra version. Science 2002; 296:2191.
7. Davidson RJ. Affective style, psychopathology, and resilience: brain mechanisms and plasticity. Am Psychol 2000; 55:1196-1214.
8. Fischer H, Tillfors M, Furmark T, Fredrikson M. Dispositional pessimism and amygdala activity: a PET study in healthy volunteers. Neuroreport 2001; 12:1635-1638.
9. Ashburner J, Friston KJ. Voxel-based morphometry: the methods. Neuroimage 2000; 11(Pt 1):805-821.
10. Costa PT, McCrae RR. Professional manual of the Revised NEO Personality Inventory and NEO Five-Factor Inventory. Odessa, Florida: Psychological Assessment Resources, Inc.; 1992.
11. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001; 14 (Pt 1):21-36.
12. Kaasinen V, Maguire RP, Kurki T, Bruck A, Rinne JO. Mapping brain structure and personality in late adulthood. Neuroimage 2005; 24:315-322.
13. Pezawas L, Meyer-Lindenberg A, Drabant EM, Verchinski BA, Munoz KE, Kolachana BS, et al. 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat Neurosci 2005; 8:828-834.
14. Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996; 274:1527-1531.
15. Boyce P, Parker G, Barnett B, Cooney M, Smith F. Personality as a vulnerability factor to depression. Br J Psychiatry 1991; 159:106-114.
16. Lange C, Irle E. Enlarged amygdala volume and reduced hippocampal volume in young women with major depression. Psychol Med 2004; 34:1059-1064.
17. Bremner JD, Narayan M, Anderson ER, Staib LH, Miller HL, Charney DS. Hippocampal volume reduction in major depression. Am J Psychiatry 2000; 157:115-118.
18. Frodl T, Meisenzahl E, Zetzsche T, Bottlender R, Born C, Groll C, et al. Enlargement of the amygdala in patients with a first episode of major depression. Biol Psychiatry 2002; 51:708-714.
19. Sheline YI, Gado MH, Price JL. Amygdala core nuclei volumes are decreased in recurrent major depression. Neuroreport 1998; 9:2023-2028.
20. Bowley MP, Drevets WC, Ongur D, Price JL. Low glial numbers in the amygdala in major depressive disorder. Biol Psychiatry 2002; 52:404-412.
21. Ashtari M, Greenwald BS, Kramer-Ginsberg E, Hu J, Wu H, Patel M, et al. Hippocampal/amygdala volumes in geriatric depression. Psychol Med 1999; 29:629-638.
22. Mervaala E, Fohr J, Kononen M, Valkonen-Korhonen M, Vainio P, Partanen K, et al. Quantitative MRI of the hippocampus and amygdala in severe depression. Psychol Med 2000; 30:117-125.