Elevated cerebral blood flow and vascular density in the amygdala after status epilepticus in rats

Neuroscience Letters

Volumn 484, Issue 1, 2010, Pages 39-42

  Hayward, Nick M E A ^a   Ndode Ekane, Xavier Ekolle ^a   Kutchiashvili, Nino ^a   Gröhn, Olli ^a   Pitkänen, Asla ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Amygdala; Cerebrovascular response; MRI; Pilocarpine; Rat; Status epilepticus

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN BLOOD VOLUME; BRAIN CORTEX; CONTROLLED STUDY; DENSITY; EPILEPTIC STATE; EPILEPTOGENESIS; HEMODYNAMICS; IMMUNOHISTOCHEMISTRY; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

AMYGDALA; ANIMALS; CEREBROVASCULAR CIRCULATION; HEMODYNAMICS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MALE; PILOCARPINE; RATS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS;

EID: 80053613956     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.08.013     Document Type: Article

References (27)

1. Ainslie P.N., Ogoh S. Regulation of cerebral blood flow in mammals during chronic hypoxia: a matter of balance. Exp. Physiol. 2010, 95(2):251-262.
2. Barbier E.L., Lamalle L., Decorps M. Methodology of brain perfusion imaging. J. Magn. Reson. Imaging 2001, 13(4):496-520.
3. Bouilleret V., Boyet S., Marescaux C., Nehlig A. Mapping of the progressive metabolic changes occurring during the development of hippocampal sclerosis in a model of mesial temporal lobe epilepsy. Brain Res. 2000, 852(2):255-262.
4. Boxerman J.L., Hamberg L.M., Rosen B.R., Weisskoff R.M. MR contrast due to intravascular magnetic susceptibility perturbations. Magn. Reson. Med. 1995, 34(4):555-566.
5. Chassagnon S., de Vasconcelos A.P., Ferrandon A., Koning E., Marescaux C., Nehlig A. Time course and mapping of cerebral perfusion during amygdala secondarily generalized seizures. Epilepsia 2005, 46(8):1178-1187.
6. Choy M., Cheung K.K., Thomas D.L., Gadian D.G., Lythgoe M.F., Scott R.C. Quantitative MRI predicts status epilepticus-induced hippocampal injury in the lithium-pilocarpine rat model. Epilepsy Res. 2010, 88(2-3):221-230.
7. Collombet J.M., Four E., Fauquette W., Burckhart M.F., Masqueliez C., Bernabe D., Baubichon D., Lallement G. Soman poisoning induces delayed astrogliotic scar and angiogenesis in damaged mouse brain areas. Neurotoxicology 2007, 28(1):38-48.
8. Dube C., Boyet S., Marescaux C., Nehlig A. Relationship between neuronal loss and interictal glucose metabolism during the chronic phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat. Exp. Neurol. 2001, 167(2):227-241.
9. Dunn J.F., Roche M.A., Springett R., Abajian M., Merlis J., Daghlian C.P., Lu S.Y., Makki M. Monitoring angiogenesis in brain using steady-state quantification of DeltaR2 with MION infusion. Magn. Reson. Med. 2004, 51(1):55-61.
10. Fabene P.F., Marzola P., Sbarbati A., Bentivoglio M. Magnetic resonance imaging of changes elicited by status epilepticus in the rat brain: diffusion-weighted and T2-weighted images regional blood volume maps and direct correlation with tissue and cell damage. Neuroimage 2003, 18(2):375-389.
11. Fernandes M.J, Dube C., Boyet S., Marescaux C., Nehlig A. Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats. J. Cereb. Blood Flow Metab. 1999, 19(2):195-209.
12. Goffin K., Nissinen J., Van Laere K., Pitkanen A. Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat. Exp. Neurol. 2007, 205(2):501-505.
13. Gross P.M., Sposito N.M., Pettersen S.E., Fenstermacher J.D. Differences in function and structure of the capillary endothelium in gray matter, white matter and a circumventricular organ of rat brain. Blood Vessels 1986, 23(6):261-270.
14. Guo Y., Gao F., Wang S., Ding Y., Zhang H., Wang J., Ding M.P. In vivo mapping of temporospatial changes in glucose utilization in rat brain during epileptogenesis: an 18F-fluorodeoxyglucose-small animal positron emission tomography study. Neuroscience 2009, 162(4):972-979.
15. Hayward N.M., Tuunanen P.I., Immonen R., Ndode-Ekane X.E., Pitkanen A., Grohn O. Magnetic resonance imaging of regional hemodynamic and cerebrovascular recovery after lateral fluid-percussion brain injury in rats. J. Cereb. Blood Flow Metab. 2010.
16. Hayward N.M.E.A., Kurkinen K.M.A., Gröhn O., Pitkänen A. Surrogate markers for epileptogenesis. Encyclopedia of Basic Epilepsy Research 2009, 259-265. Academic Press, Oxford. A.S. Philip (Ed.).
17. Kahane P., Merlet I., Gregoire M.C., Munari C., Perret J., Mauguiere F. An H(2) (15)O-PET study of cerebral blood flow changes during focal epileptic discharges induced by intracerebral electrical stimulation. Brain 1999, 122:1851-1865. (Part 10).
18. Kharatishvili I., Immonen R., Grohn O., Pitkanen A. Quantitative diffusion MRI of hippocampus as a surrogate marker for post-traumatic epileptogenesis. Brain 2007, 130(Pt 12):3155-3168.
19. Leroy C., Roch C., Koning E., Namer I.J., Nehlig A. In the lithium-pilocarpine model of epilepsy, brain lesions are not linked to changes in blood-brain barrier permeability: an autoradiographic study in adult and developing rats. Exp. Neurol. 2003, 182(2):361-372.
20. Marcon J, Gagliardi B., Balosso S., Maroso M., Noe F., Morin M., Lerner-Natoli M., Vezzani A., Ravizza T. Age-dependent vascular changes induced by status epilepticus in rat forebrain: implications for epileptogenesis. Neurobiol. Dis. 2009, 34(1):121-132.
21. Ndode-Ekane X.E., Hayward N., Grohn O., Pitkanen A. Vascular changes in epilepsy: functional consequences and association with network plasticity in pilocarpine-induced experimental epilepsy. Neuroscience 2010, 166(1):312-332.
22. Paxinos G.T., Watson C. The Rat Brain in Stereotaxic Coordinates 1998, Academic Press, London.
23. Pitkanen A., Lukasiuk K. Molecular and cellular basis of epileptogenesis in symptomatic epilepsy. Epilepsy Behav. 2009, 1(Suppl. 14):16-25.
24. Pitkanen A., Tuunanen J., Kalviainen R., Partanen K., Salmenpera T. Amygdala damage in experimental and human temporal lobe epilepsy. Epilepsy Res. 1998, 32(1-2):233-253.
25. Theodore W.H., Katz D., Kufta C., Sato S., Patronas N., Smothers P., Bromfield E. Pathology of temporal lobe foci: correlation with CT, MRI, and PET. Neurology 1990, 40(5):797-803.
26. van Vliet E.A, da Costa Araujo S., Redeker S., van Schaik R., Aronica E., Gorter J.A. Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy. Brain 2007, 130:521-534. Pt 2.
27. Williams D.S., Detre J.A., Leigh J.S., Koretsky A.P. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc. Natl. Acad. Sci. U.S.A. 1992, 89(1):212-216.