Crucial effects of amino acid side chain length in transmembrane segment 5 on substrate affinity in yeast glucose transporter Hxt7

Biochemistry

Volumn 50, Issue 40, 2011, Pages 8674-8681

  Kasahara, Toshiko ^a   Shimogawara, Kosuke ^a   Kasahara, Michihiro ^a,b  

^a School of Medicine   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYS REPLACEMENT; CYSTEINE-SCANNING MUTAGENESIS; D-GLUCOSE; EFFECTS OF AMINO ACIDS; FUNCTIONAL TRANSPORTERS; GLUCOSE TRANSPORT; GLUCOSE TRANSPORTERS; HOMOLOGY MODELS; KEY DETERMINANTS; SIDE CHAIN LENGTHS; STRUCTURAL BASIS; SUBSTRATE AFFINITY; SUBSTRATE RECOGNITION; SUBSTRATE RECOGNITION SITES; SULFHYDRYL; TRANSMEMBRANE SEGMENTS; TRANSPORT ACTIVITY; VAN DER WAALS; WILD TYPES;

AMINO ACIDS; CHAIN LENGTH; SUBSTRATES; VAN DER WAALS FORCES; YEAST;

GLUCOSE;

AMINO ACID; CHLOROMERCURIBENZENESULFONIC ACID; DEOXYGLUCOSE; GLUCOSE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER HXT7; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; HYDROPHILICITY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; WILD TYPE; YEAST;

AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; GLUCOSE; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONOSACCHARIDE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

SACCHAROMYCES CEREVISIAE;

EID: 80053609137     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200958s     Document Type: Article

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