Simultaneous determination of fluoxetine and its major active metabolite norfluoxetine in human plasma by LC-MS/MS using supported liquid extraction

Biomedical Chromatography

Volumn 25, Issue 11, 2011, Pages 1245-1251

  Li, Yu ^a   Emm, Thomas ^a   Yeleswaram, Swamy ^a  

^a Experimental Station   (United States)

Author keywords

Fluoxetine; Human plasma; LC MS MS determination; Norfluoxetine; Supported liquid extraction

Indexed keywords

COLUMN CHROMATOGRAPHY; DRUG PRODUCTS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PATIENT MONITORING; PLASMA (HUMAN); SOLVENT EXTRACTION;

ACTIVE METABOLITES; ANALYTES; BIOANALYTICAL METHODS; FLUOXETINE; HUMAN PLASMAS; LC-MS-MS; LC-MS/MS DETERMINATION; NORFLUOXETINE; SIMULTANEOUS DETERMINATIONS; SUPPORTED LIQUID EXTRACTIONS;

METABOLITES;

FLUOXETINE; NORFLUOXETINE; TERT BUTYL METHYL ETHER;

ACCURACY; ARTICLE; DRUG DETERMINATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; ANALOGS AND DERIVATIVES; BLOOD; CHEMISTRY; DRUG STABILITY; ISOLATION AND PURIFICATION; LIQUID LIQUID EXTRACTION; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL;

CHROMATOGRAPHY, LIQUID; DRUG STABILITY; FLUOXETINE; HUMANS; LINEAR MODELS; LIQUID-LIQUID EXTRACTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 80053607010     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1597     Document Type: Article

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