Liquid chromatography/tandem mass spectrometry for the determination of fluoxetine and its main active metabolite norfluoxetine in human plasma with deuterated fluoxetine as internal standard

Rapid Communications in Mass Spectrometry

Volumn 16, Issue 19, 2002, Pages 1844-1850

  Li, Chuan ^a   Ji, Zhouhua ^a   Nan, Fajun ^a   Shao, Qingxiang ^b   Liu, Ping ^c   Dai, Jieyu ^a   Zhen, Jiang ^a   Yuan, Hao ^a   Xu, Fang ^a   Cui, Jian ^c   Huang, Bin ^c   Zhang, Meiyun ^b   Yu, Cheng ^d  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c Eli Lilly and Company   (China)

^d SHANGHAI XUHUI CENTRAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ACTIVE METABOLITES; FLUOXETINE; HUMAN PLASMAS; INTERNAL STANDARDS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; NORFLUOXETINE; RAPID METHOD; SELECTIVE INHIBITORS; SIMULTANEOUS DETERMINATIONS;

METABOLITES;

ANTIDEPRESSANT AGENT; ANTIDEPRESSIVE AGENTS, SECOND GENERATION; DEUTERIUM; FLUOXETINE; NORFLUOXETINE; SOLVENT;

ADULT; ANALYTIC METHOD; ANTICHOLINERGIC EFFECT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD; BLOOD SAMPLING; CALIBRATION; CHROMATOGRAPHY; CLINICAL TRIAL; DEMETHYLATION; DRUG DETERMINATION; ENANTIOMER; HALF LIFE TIME; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MONITORING; QUALITY CONTROL; REPRODUCIBILITY; STANDARD; TANDEM MASS SPECTROMETRY;

EID: 0036382622     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.800     Document Type: Article

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