Hypertensive retinopathy signs as risk indicators of cardiovascular morbidity and mortality

British Medical Bulletin

Volumn 73-74, Issue , 2005, Pages 57-70

  Tien, Yin Wong ^a,b   McIntosh, Rachel ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ATHEROSCLEROSIS; BLEEDING; BLOOD PRESSURE; CARDIOVASCULAR RISK; CEREBROVASCULAR DISEASE; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; HUMAN; INCIDENCE; MICROANEURYSM; MORBIDITY; MORTALITY; PREDICTION; PRIORITY JOURNAL; RETINOPATHY; RISK ASSESSMENT; RISK FACTOR; STROKE;

ATHEROSCLEROSIS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; CEREBROVASCULAR DISORDERS; HEART DISEASES; HUMANS; HYPERTENSION; PREVALENCE; PROGNOSIS; RETINAL DISEASES; RETINAL VESSELS; RISK FACTORS;

EID: 29644441801     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldh050     Document Type: Article

References (53)

1. Wong TY, Mitchell P (2004) Hypertensive retinopathy. N Engl J Med 351, 2310-17.
2. Tso M, Jampol LM (1982) Pathophysiology of hypertensive retinopathy. Ophthalmology, 89, 1132-45.
3. Wong TY, Klein R, Klein BEK, Tielsch JM, Hubbard LD, Nieto FJ (2001) Retinal microvascular abnormalities, and their relation to hypertension, cardiovascular diseases and mortality. Surv Ophthalmol, 46, 59-80.
4. Gunn RM (1892) Ophthalmoscopic evidence of (1) arterial changes associated with chronic renal diseases and (2) of increased arterial tension. Trans Am Ophthalmol Soc, 12, 124-5.
5. Gunn RM (1898) On ophthalmoscopic evidence of general arterial disease. Trans Ophthalmol Soc UK, 18, 356-81.
6. Williams B, Poulter NR, Brown MJ, Davis M, McInnes GT, Potter JF, Sever PS, Thom SM. British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary. Bmj 2004; 328: 634-40
7. Chobanian AV, Bakris GL, Black H.R et al. (2003)The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC7 Report. JAMA, 289: 2560-72.
8. Keith NM, Wagener HP, Barker NW (1939) Some different typs of essential hypertension: their course and prognosis. Am J Med Sci, 197, 332-43.
9. Dodson PM, Lip GY, Eames SM, Gibson JM, Beevers DG (1996) Hypertensive retinopathy: a review of existing classification systems and a suggestion for a simplified grading system. J Hum Hypertens, 10, 93-8.
10. Klein R, Klein BEK, Moss SE (1997) The relation of systemic hypertension to changes in the retinal vasculature. The Beaver Dam Eye Study. Trans Am Ophthalmol Soc, 95, 329-50.
11. Klein R, Klein BEK, Moss SE, Wang Q (1994) Hypertension and retinopathy, arteriolar narrowing and arteriovenous nicking in a population. Arch Ophthalmol, 112, 92-8.
12. Klein R, Sharrett AR, Klein BEK et al. Are retinal arteriolar abnormalities related to atherosclerosis? The Atherosclerosis in Communities Study. Arterioscler Thromb Vasc Biol, 20, 1644-50.
13. Sharp PS, Chaturvedi N, Wormald R et al. (1995) Hypertensive retinopathy in Afro-Caribbeans and Europeans. Prevalence and risk factor relationships. Hypertension, 25, 1322-5.
14. Stolk RP, Vingerling JR, de Jong PT et al. Retinopathy, glucose, and insulin in an elderly population. The Rotterdam Study. Diabetes, 44, 11-15.
15. Wang JJ, Mitchell P, Leung H, Rochtchina E, Wong TY, Klein R (2003) Hypertensive retinal vessel wall signs in the general older population: the Blue Mountains Eye Study. Hypertension, 42, 534-41.
16. Wong TY, Klein R, Sharret AR et al. 2003, The prevalence and risk factors of retinal microvascular abnormalities in older people. The Cardiovascular Health Study. Ophthalmology, 110, 658-66.
17. Yu T, Mitchell P, Berry G, Li W, Wang JJ (1998) Retinopathy in older persons without diabetes and its relationship to hypertension. Arch Ophthalmol, 116, 83-9.
18. Ikram MK, de Jong FJ, Vingerling JR et al. (2004) Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study. Invest Ophthalmol Vis Sci, 45, 2129-34.
19. Leung H, Wang JJ, Rochtchina E et al. (2003) Relationships between age, blood pressure and retinal vessel diameters in an older population. Invest Ophthalmol Vis Sci, 44, 2900-4.
20. Sharret AR, Hubbard LD, Cooper LS et al. (1999) Retinal arteriolar diameters and elevated blood pressure. The Atherosclerosis Risk in Communities Study. Am J Epidemiol, 150, 263-70.
21. Wong TY, Hubbard LD, Klein R et al. (2002) Retinal microvascular abnormalities and blood pressure in older people: The Cardiovascular Health Study. Br J Ophthalmol, 86, 1007-13.
22. Wong TY, Klein R, Klein BEK, Meuer SM, Hubbard LD (2003) Retinal vessel diameters and their associations with age and blood pressure. Invest Ophthalmol Vis Sci, 44, 4644-50.
23. Leung H, Wang JJ, Rochtchina E, Wong TY, Klein R, Mitchell P (2004) Impact of current and past blood pressure on retinal arteriolar diameter in an older population. J Hypertens, 22, 1543-9.
24. van Leiden HA, Dekker JM, Moll AC et al. (2003) Risk factors for incident retinopathy in a diabetic and nondiabetic population: the Hoorn Study. Arch Ophthalmol, 121, 245-51.
25. Wong TY, Duncan BB, Golden SH et al. (2004) Associations between the metabolic syndrome and retinal microvascular signs: the Atherosclerosis Risk in Communities Study. Invest Ophthalmol Vis Sci, 45, 2949-54.
26. Svarsudd K, Wedel H, Aurell E, Tibber G (1978) Hypertensive eye ground changes: prevalence, relation to blood pressure and prognostic importance. Acta Med Scand, 1978; 204: 159-167.
27. Tanaka H, Hayashi M, Date C et al. (1985) Epidemiolgic studies of stroke in Shibata, a Japanese provincial cuty: preliminary report on risk factors for cerebral infaction. Stroke, 16, 773-80.
28. Nakayama T, Date C, Yokoyama T, Yoshiike N, Yamaguchi M, Tanaka H (1997) A 15.5-year follow-up study of stroke in a Japanese provincial city. The Shibata Study. Stroke, 28, 45-52.
29. Wong TY, Klein R, Nieto FJ et al. (2003) Retinal microvascular abnormalities and ten-year cardiovascular mortality. A population-based case-control study. Ophthalmology, 110, 933-40.
30. Wong TY, Klein R, Couper DJ et al. (2001) Retinal microvascular abnormalities and incident clinical strokes. The Atherosclerosis Risk in the Communities Study. Lancet, 258, 1134-40.
31. Wong TY, Klein R, Sharret AR, et al. (2002) Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in Communities Study. Stroke, 33, 1487-92.
32. Wong TY, Klein R, Sharret AR et al. (2002) Cerebral white matter lesion, retinopathy and risk of clinical stroke: The Atherosclerosis Risk in the Communities Study. JAMA, 288, 67-74.
33. Wong TY, Mosley TH, Klein R (2003). Retinal microvascular abnormalities and MRI signs of cerebral atrophy in healthy, middle-aged people. Neurology, 61, 806-11.
34. Breslin DJ, Gifford RWJ, Fairbairn JFI (1966) Essential hypertension: a twenty year follow-up study. Circulation, 33, 87-97.
35. Michelson EL, Morganroth J, Nichols CW, MacVaugh H (1979) Retinal arteriolar changes as an indicator of coronary artery disease. Arch Intern Med, 139, 1139-41.
36. Duncan BB, Wong TY, Tyroler HA, Davis CE, Fuchs FD (2002) Hypertensive retinopathy and incident coronary heart disease in high risk men. Br J Ophthalmol, 86, 1002-6.
37. Wong TY, Klein R, Sharret AR et al. (2002) Retinal arteriolar narrowing and incident coronary heart disease in men and women: The Atherosclerosis Risk in the Communities Study. JAMA, 287, 1153-9.
38. Wong TY, Rosamond W, Chang PP et al. (2005) Retinopathy and risk of congestive heart failure. JAMA, 293, 63-9.
39. Wong TY, Coresh J, Klein R et al. (2004) Retinal microvascular abnormalities and renal dysfunction in middle-aged people. J Am Soc Nephrol, 15, 2469-76.
40. Smith W, Wang JJ, Wong TY et al. (2004) Retinal arteriolar narrowing is associated with 5-year incident severe hypertension. The Blue Mountains Eye Study. Hypertension, 44, 442-7.
41. Wong TY, Klein R, Sharret AR et al. (2004) Retinal arteriolar diameters and risk of hypertension. Ann Intern Med, 140, 248-55.
42. Wong TY, Shankar A, Klein R, Klein BEK, Hubbard LD (2004) Prospective cohort study of retinal vessel diameters and risk of hypertension. BMJ, 329, 79-82.
43. Wong TY, Klein R, Sharret AR et al. (2002) Retinal arteriolar narrowing and risk of diabetes in middle-aged persons. JAMA, 287, 2528-33.
44. Wong TY, Shankar A, Klein R, Klein BEK, Hubbard LD (2005) Retinal arteriolar narrowing, hypertension and subsequent risk of diabetes mellitus. Arch Intern Med, 165, 1060-5.
45. Breckenridge A, Dollery CT, Parry EH (1970) Prognosis of treated hypertension. Changes in life expectancy and causes of death between 1952 and 1967. Q J Med, 155, 411-29.
46. Breslin DJ, Gifford RWJ, Fairbairn JFI, Kearns TP (1966) Prognostic importance of ophthalmoscopic findings in essential hypertension. JAMA, 195, 335-8.
47. Frant R, Groen J (1950) Prognosis of vascular hypertension: A nine year follow-up study of four hundred and eighteen cases. Arch Intern Med, 85, 727.
48. Palmer RS, Loofbourow D, Doering CR (1948) Prognosis in essential hypertension: eight-year follow-up study of 430 patients on conventional medical treatment. N Engl J Med, 239, 990.
49. Hamada Y, Niisato E, Otori T et al. (1995) Ocular fundus changes in malignant or precocious stroke-prone spontaneously hypertensive rats after administration of antihypertensive drugs. Clin Exp Pharmacol Physiol Suppl, 22, S132-3.
50. Morishita R, Higaki J, Nakamura F et al. (1992) Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat. Blood Press Suppl, 3, 41-7.
51. Bock KD (1984) Regression of retinal vascular changes by antihypertensive therapy. Hypertension, 6, 158-62.
52. Strachan MW, McKnight JA (2005) Improvement in hypertensive retinopathy after treatment of hypertension. N Engl J Med, 352, e17
53. Dahlof B, Stenkula S, Hansson L (1992) Hypertensive retinal vascular changes before and after treatment. Blood Press, 1, 35-44.