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Volumn 3, Issue 10, 2011, Pages 1049-1055

LC- and CZE-ICP-MS approaches for the in vivo analysis of the anticancer drug candidate sodium trans-[tetrachloridobis(1H-indazole)ruthenate(iii)] (KP1339) in mouse plasma

(7) Bytzek, Anna K a Boeck, Katharina b Hermann, Gerrit b Hann, Stephan b Keppler, Bernhard K a Hartinger, Christian G a Koellensperger, Gunda b

a UNIVERSITY OF VIENNA (Austria)

b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS TIME; ANALYTICAL METHODOLOGY; ANTI-CANCER AGENTS; ANTICANCER DRUG; BIOLOGICAL BINDING; BLOOD PLASMA; BLOOD SAMPLES; CAPILLARY ZONE ELECTROPHORESIS; CLINICAL TRIAL; IN-VIVO; IN-VIVO ANALYSIS; INDAZOLE; MODE OF ACTION; MOUSE PLASMA; PROTEIN BINDING; RUTHENATES; SAMPLE CONSUMPTION; SERUM PROTEINS; SIZE EXCLUSION; TIME POINTS; UNTREATED CONTROL;

BIOCHEMISTRY; BLOOD; CAPILLARY ELECTROPHORESIS; INDUCTIVELY COUPLED PLASMA; MASS SPECTROMETERS; MASS SPECTROMETRY; PROTEINS; RUTHENIUM; RUTHENIUM COMPOUNDS; SODIUM; STOICHIOMETRY;

MAMMALS;

ALBUMIN; ANTINEOPLASTIC AGENT; KP 1339; SODIUM TRANS[TETRACHLORIDOBIS(1H INDAZOLE)RUTHENATE(III)]; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANION EXCHANGE CHROMATOGRAPHY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG PROTEIN BINDING; GEL PERMEATION CHROMATOGRAPHY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOICHIOMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, GEL; ELECTROPHORESIS, CAPILLARY; INDAZOLES; LIMIT OF DETECTION; MASS SPECTROMETRY; MICE; ORGANOMETALLIC COMPOUNDS; PROTEIN BINDING; RUTHENIUM; SERUM ALBUMIN;

MUS;

EID: 80053597770 PISSN: 17565901 EISSN: 1756591X Source Type: Journal
DOI: 10.1039/c1mt00055a Document Type: Article

Times cited : (58)

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