Age-specific incidence data indicate four mutations are required for human testicular cancers

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Brody, James P ^a  

^a University of California at Irvine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN;

ACCURACY; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER GENETICS; CANCER GROWTH; CANCER INCIDENCE; CHILD; CONTROLLED STUDY; DATA ANALYSIS; EPIGENETICS; GERM CELL TUMOR; GONADAL CELL TUMOR; HUMAN; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MUTATION RATE; MUTATIONAL ANALYSIS; RETROSPECTIVE STUDY; SCHOOL CHILD; TESTIS CANCER; ADOLESCENT; GENETICS; INCIDENCE; MIDDLE AGED; MUTATION; PATHOLOGY; STATISTICAL MODEL; TESTIS TUMOR;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MODELS, STATISTICAL; MUTATION; TESTICULAR NEOPLASMS; YOUNG ADULT;

EID: 80053581708     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025978     Document Type: Article

References (51)

1. Fearon ER, Hamilton SR, Vogelstein B, (1987) Clonal analysis of human colorectal tumors. Science 238: 193-197.
2. Fearon ER, Vogelstein B, (1990) A genetic model for colorectal tumorigenesis. Cell 61: 759-767.
3. Vogelstein B, Kinzler KW, (1993) The multistep nature of cancer. Trends Genet 9: 138-141.
4. Hanahan D, Weinberg RA, (2000) The hallmarks of cancer. Cell 100: 57-70.
5. Hahn WC, Weinberg RA, (2002) Modelling the molecular circuitry of cancer. Nat Rev Cancer 2: 331-341.
6. Hahn WC, Weinberg RA, (2002) Rules for making human tumor cells. N Engl J Med 347: 1593-1603.
7. Stratton MR, Campbell PJ, Futreal PA, (2009) The cancer genome. Nature 458: 719-724.
8. Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, et al. (2007) The genomic landscapes of human breast and colorectal cancers. Science 318: 1108-1113.
9. Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, et al. (2008) Somatic mutations affect key pathways in lung adenocarcinoma. Nature 455: 1069-1075.
10. Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, et al. (1999) Creation of human tumour cells with defined genetic elements. Nature 400: 464-468.
11. Byrne HM, (2010) Dissecting cancer through mathematics: from the cell to the animal model. Nat Rev Cancer 10: 221-230.
12. Armitage P, Doll R, (1954) The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 8: 1-12.
13. Moolgavkar SH, (2004) Commentary: Fifty years of the multistage model: remarks on a landmark paper. Int J Epidemiol 33: 1182-1183.
14. Oosterhuis JW, Looijenga LHJ, (2005) Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 5: 210-222.
15. Houldsworth J, Korkola JE, Bosl GJ, Chaganti RSK, (2006) Biology and genetics of adult male germ cell tumors. J Clin Oncol 24: 5512-5518.
16. Manecksha RP, Fitzpatrick JM, (2009) Epidemiology of testicular cancer. BJU Int 104: 1329-1333.
17. Westergaard T, Olsen JH, Frisch M, Kroman N, Nielsen JW, et al. (1996) Cancer risk in fathers and brothers of testicular cancer patients in Denmark. a population-based study. Int J Cancer 66: 627-631.
18. Czene K, Lichtenstein P, Hemminki K, (2002) Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-Cancer Database. Int J Cancer 99: 260-266.
19. Shah MN, Devesa SS, Zhu K, McGlynn KA, (2007) Trends in testicular germ cell tumours by ethnic group in the United States. Int J Androl 30: 206-13; discussion 213-4.
20. Chia VM, Quraishi SM, Devesa SS, Purdue MP, Cook MB, et al. (2010) International trends in the incidence of testicular cancer, 1973-2002. Cancer Epidemiol Biomarkers Prev 19: 1151-1159.
21. Pettersson A, Richiardi L, Nordenskjold A, Kaijser M, Akre O, (2007) Age at surgery for unde-scended testis and risk of testicular cancer. N Engl J Med 356: 1835-1841.
22. Trichopoulos D, (1990) Hypothesis: does breast cancer originate in utero? Lancet 335: 939-940.
23. Ekbom A, (1998) Growing evidence that several human cancers may originate in utero. Seminars in Cancer Biology 8: 237-244.
24. Rothman N, Wacholder S, Caporaso NE, Garcia-Closas M, Buetow K, et al. (2001) The use of common genetic polymorphisms to enhance the epidemiologic study of environmental carcinogens. Biochim Biophys Acta 1471: C1-10.
25. Thilly WG, (2003) Have environmental mutagens caused oncomutations in people? Nat Genet 34: 255-259.
26. Myrup C, Schnack TH, Wohlfahrt J, (2007) Correction of cryptorchidism and testicular cancer. N Engl J Med 357: 825-7; author reply 825-7.
27. Kanetsky PA, Mitra N, Vardhanabhuti S, Li M, Vaughn DJ, et al. (2009) Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nat Genet 41: 811-815.
28. Rapley EA, Turnbull C, Olama AAA, Dermitzakis ET, Linger R, et al. (2009) A genome-wide association study of testicular germ cell tumor. Nat Genet 41: 807-810.
29. Chanock S, (2009) High marks for GWAS. Nat Genet 41: 765-766.
30. Mdzinarishvili T, Sherman S, (2010) Weibull-like model of cancer development in aging. Cancer Inform 9: 179-188.
31. Frank SA, (2007) Dynamics of Cancer: Incidence, Inheritance, and Evolution Princeton Princeton University Press.
32. Frank SA, (2004) Age-specific acceleration of cancer. Curr Biol 14: 242-246.
33. Harding C, Pompei F, Lee EE, Wilson R, (2008) Cancer suppression at old age. Cancer Res 68: 4465-4478.
34. Ritter G, Wilson R, Pompei F, Burmistrov D, (2003) The multistage model of cancer development: some implications. Toxicol Ind Health 19: 125-145.
35. Pompei F, Wilson R, (2002) A quantitative model of cellular senescence inuence on cancer and longevity. Toxicol Ind Health 18: 365-376.
36. Zhang X, Simon R, (2005) Estimating the number of rate limiting genomic changes for human breast cancer. Breast Cancer Res Treat 91: 121-124.
37. Moger TA, Aalen OO, Halvorsen TO, Storm HH, Tretli S, (2004) Frailty modelling of testicular cancer incidence using scandinavian data. Biostatistics 5: 1-14.
38. Arnheim N, Calabrese P, (2009) Understanding what determines the frequency and pattern of human germline mutations. Nat Rev Genet 10: 478-488.
39. Loeb LA, Loeb KR, Anderson JP, (2003) Multiple mutations and cancer. Proc Natl Acad Sci U S A 100: 776-781.
40. Moolgavkar SH, Luebeck EG, (2003) Multistage carcinogenesis and the incidence of human cancer. Genes Chromosomes Cancer 38: 302-306.
41. Luebeck EG, Moolgavkar SH, (2002) Multistage carcinogenesis and the incidence of colorectal cancer. Proc Natl Acad Sci U S A 99: 15095-15100.
42. Meza R, Jeon J, Moolgavkar SH, Luebeck EG, (2008) Age-specific incidence of cancer: Phases, transitions, and biological implications. Proc Natl Acad Sci U S A 105: 16284-16289.
43. Looijenga LH, Oosterhuis JW, (1999) Pathogenesis of testicular germ cell tumours. Rev Reprod 4: 90-100.
44. Clayton D, Schiffers E, (1987) Models for temporal variation in cancer rates. II: Age-period-cohort models. Stat Med 6: 469-481.
45. Clayton D, Schiffers E, (1987) Models for temporal variation in cancer rates. I: Age-period and age-cohort models. Stat Med 6: 449-467.
46. Thornburg KL, Shannon J, Thuillier P, Turker MS, (2010) In utero life and epigenetic predisposition for disease. Adv Genet 71: 57-78.
47. Johnson N, Kemp A, Kotz S, (2005) Univariate discrete distributions. Wiley series in probability and mathematical statistics. Applied probability and statistics. Wiley.
48. Calabrese P, Tavar S, Shibata D, (2004) Pretumor progression: clonal evolution of human stem cell populations. Am J Pathol 164: 1337-1346.
49. National Cancer Institute. Surveillance, Epidemiology, and End Results (SEER) Program (2010) SEER*Stat database: Incidence- seer 17.
50. National Cancer Institute Surveillance Research Program. SEER*Stat software. version 6.6.2 [Computer software].
51. Brody JP, (2009) Parallel routes of human carcinoma development: implications of the age-specific incidence data. PLoS One 4: e7053.