Age-specific incidence of cancer: Phases, transitions, and biological implications

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 42, 2008, Pages 16284-16289

  Meza, Rafael ^a   Jeon, Jihyoun ^a   Moolgavkar, Suresh H ^a,b   Georg Luebeck, E ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b EXPONENT INC   (United States)

Author keywords

Colorectal; Knudson's "two hit" hypothesis; Multistage carcinogenesis; Neoplastic progression; Pancreatic

Indexed keywords

APC; CYCLIN DEPENDENT KINASE INHIBITOR 2A;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER EPIDEMIOLOGY; CANCER GROWTH; CANCER INCIDENCE; CANCER REGISTRY; CARCINOGENESIS; CELL DIFFERENTIATION; CHILD; COLORECTAL CANCER; CONTROLLED STUDY; DATA ANALYSIS; FEMALE; GENE ACTIVATION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MALIGNANT TRANSFORMATION; PANCREAS CANCER; PRECANCER; PREDICTION; PRIORITY JOURNAL;

AGE DISTRIBUTION; BIOLOGY; FEMALE; HUMANS; MALE; NEOPLASMS; SEX CHARACTERISTICS; TIME FACTORS;

PYRONIA TITHONUS;

EID: 55849135224     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0801151105     Document Type: Article

References (55)

1. Muller HJ (1951) Radiation damage to the genetic material. Sci Prog 7:93-165, 481-493.
2. Nordling CO (1953) A new theory on cancer-inducing mechanism. Br J Cancer 7:68-72.
3. Armitage P, Doll R (1954) The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 8:1-12.
4. Moolgavkar SH (1991) Stochastic Models of Carcinogenesis, eds Rao CR, Chakraborty R (Elsevier, New York), pp 372-393.
5. Nowell PC (1976) The clonal evolution of tumor cell populations. Science 194:23-28.
6. Renan MJ (1993) How many mutations are required for tumorigenesis? Implications from human cancer data. Mol Carcinog 7:139-146.
7. Pierce DA, Mendelsohn ML (1999) A model for radiation-related cancer suggested by atomic bomb survivor data. Radiat Res 152:642-654.
8. Frank SA (2005) Age-specific incidence of inherited versus sporadic cancers: A test of the multistage theory of carcinogenesis. Proc Natl Acad Sci USA 102:1071-1075.
9. Cairns J (2002) Somatic stem cells and the kinetics of mutagenesis and carcinogenesis. Proc Natl Acad Sci USA 99:10567-10570.
10. Frank SA, Nowak MA (2003) Developmental predisposition to cancer. Nature 422:494.
11. Loeb LA (2001) A mutator phenotype in cancer. Cancer Res 61:3230-3239.
12. Uys P, van Helden PD (2003) On the nature of genetic changes required for the development of esophageal cancer. Mol Carcinog 36:82-89.
13. Calabrese P, Tavare S, Shibata D (2004) Pretumor progression: Clonal evolution of human stem cell populations. Am J Pathol 164:1337-1346.
14. Hornsby C, Page KM, Tomlinson IP (2007) What can we learn from the population incidence of cancer? Armitage and Doll revisited. Lancet Oncol 8:1030-1038.
15. Holford TR (1991) Understanding the effects of age, period, and cohort on incidence and mortality rates. Annu Rev Public Health 12:425-457.
16. Chu KC, Tarone RE, Chow WH, Hankey BF, Ries LA (1994) Temporal patterns in colorectal cancer incidence, survival, and mortality from 1950 through 1990. J Natl Cancer Inst 86:997-1006.
17. Cress RD, Morris C, Ellison GL, Goodman MT (2006) Secular changes in colorectal cancer incidence by subsite, stage at diagnosis, and race/ethnicity, 1992-2001. Cancer 107:1142-1152.
18. Larsson SC, Wolk A (2007) Obesity and colon and rectal cancer risk: A meta-analysis of prospective studies. Am J Clin Nutr 86:556-565.
19. Clayton D, Schifflers E (1987) Models for temporal variation in cancer rates. I: Age-period and age-cohort models. Stat Med 6:449-467.
20. Clayton D, Schifflers E (1987) Models for temporal variation in cancer rates. II: Age-period-cohort models. Stat Med 6:469-481.
21. Luebeck EG, Moolgavkar SH (2002) Multistage carcinogenesis and the incidence of colorectal cancer. Proc Natl Acad Sci USA 99:15095-15100.
22. Moolgavkar SH, Venzon DJ (1979) Two-event models for carcinogenesis: Incidence curves for childhood and adult tumors. Math Biosci 47:55-77.
23. Moolgavkar SH, Luebeck G (1990) Two-event model for carcinogenesis: Biological, mathematical, and statistical considerations. Risk Anal 10:323-341.
24. Heidenreich WF, Luebeck EG, Moolgavkar SH (1997) Some properties of the hazard function of the two-mutation clonal expansion model. Risk Anal 17:391-399.
25. Knudson AG (1971) Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820-823.
26. Knudson AG (2000) Chasing the cancer demon. Annu Rev Genet 34:1-19.
27. Knudson AG (2001) Two genetic hits (more or less) to cancer. Nat Rev Cancer 1:157-162.
28. Bodmer WF, et al. (1987) Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 328:614-616.
29. Miyoshi Y, et al. (1992) Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene. Hum Mol Genet 1:229-233.
30. Kinzler KW, et al. (1991) Identification of FAP locus genes from chromosome 5q21. Science 253:661-665.
31. Goss KH, Groden J (2000) Biology of the adenomatous polyposis coli tumor suppressor. J Clin Oncol 18:1967-1979.
32. Segditsas S, Tomlinson I (2006) Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 25:7531-7537.
33. Meza R, Luebeck EG, Moolgavkar SH (2005) Gestational mutations and carcinogenesis. Math Biosci 197:188-210.
34. Herrero-Jimenez P, Tomita-Mitchell A, Furth EE, Morgenthaler S, Thilly WG (2000) Population risk and physiological rate parameters for colon cancer. The union of an explicit model for carcinogenesis with the public health records of the United States. Mutat Res 447:73-116.
35. Moolgavkar SH, Stevens RG (1981) Smoking and cancers of bladder and pancreas: Risks and temporal trends. J Natl Cancer Inst 67:15-23.
36. Fuchs CS, et al. (1996) A prospective study of cigarette smoking and the risk of pancreatic cancer. Arch Intern Med 156:2255-2260.
37. Winawer SJ, et al. (2006) Guidelines for colonoscopy surveillance after polypectomy: A consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. CA Cancer J Clin 56:143-159.
38. Vogelaar I, et al. (2006) How much can current interventions reduce colorectal cancer mortality in the U.S.? Mortality projections for scenarios of risk-factor modification, screening, and treatment. Cancer 107:1624-1633.
39. Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767.
40. Groden J, et al. (1995) Response of colon cancer cell lines to the introduction of APC, a colon-specific tumor suppressor gene. Cancer Res 55:1531-1539.
41. Hruban RH, Goggins M, Parsons J, Kern SE (2000) Progression model for pancreatic cancer. Clin Cancer Res 6:2969-2972.
42. Winawer SJ, et al. (1997) Colorectal cancer screening: Clinical guidelines and rationale. Gastroenterology 112:594-642.
43. Ness RM, Holmes AM, Klein R, Dittus R (2000) Cost-utility of one-time colonoscopic screening for colorectal cancer at various ages. Am J Gastroenterol 95:1800-1811.
44. Jones S, et al. (2008) Comparative lesion sequencing provides insights into tumor evolution. Proc Natl Acad Sci USA 105:4283-4288.
45. Hazelton WD, Clements MS, Moolgavkar SH (2005) Multistage carcinogenesis and lung cancer mortality in three cohorts. Cancer Epidemiol Biomarkers Prev 14:1171-1181.
46. Meza R, Hazelton W, Colditz G, Moolgavkar S (2008) Analysis of lung cancer incidence in the nurses' health and the health professionals' follow-up studies using a multistage carcinogenesis model. Cancer Causes Control 19:317-328.
47. Jeon J, Luebeck EG, Moolgavkar SH (2006) Age effects and temporal trends in adenocarcinoma of the esophagus and gastric cardia (United States). Cancer Causes Control 17:971-981.
48. Potten CS, Booth C, Hargreaves D (2003) The small intestine as a model for evaluating adult tissue stem cell drug targets. Cell Prolif 36:115-129.
49. Nicolas P, Kim KM, Shibata D, Tavare S (2007) The stem cell population of the human colon crypt: Analysis via methylation patterns. PLoS Comput Biol 3:e28.
50. Iwama T (2001) Somatic mutation rate of the APC gene. Jpn J Clin Oncol 31:185-187.
51. Herrero-Jimenez P, et al. (1998) Mutation, cell kinetics, and subpopulations at risk for colon cancer in the United States. Mutat Res 400:553-578.
52. Heidenreich WF, Luebeck EG, Hazelton WD, Paretzke HG, Moolgavkar SH (2002) Multistage models and the incidence of cancer in the cohort of atomic bomb survivors. Radiat Res 158:607-614.
53. Komarova NL, Lengauer C, Vogelstein B, Nowak MA (2002) Dynamics of genetic instability in sporadic and familial colorectal cancer. Cancer Biol Ther 1:685-692.
54. Nowak MA, et al. (2002) The role of chromosomal instability in tumor initiation. Proc Natl Acad Sci USA 99:16226-16231.
55. Morgenthaler S, Herrero P, Thilly WG (2004) Multistage carcinogenesis and the fraction at risk. J Math Biol 49:455-467.