Optimal response-adaptive randomized designs for multi-armed survival trials

Statistics in Medicine

Volumn 30, Issue 24, 2011, Pages 2890-2910

  Sverdlov, Oleksandr ^a   Tymofyeyev, Yevgen ^b   Wong, Weng Kee ^c  

^a BRISTOL MYERS SQUIBB   (United States)

^b JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Doubly adaptive biased coin; Ethics; Optimal allocation; Power; Response adaptive randomization; Survival trials

Indexed keywords

CARBOPLATIN; CISPLATIN;

ARTICLE; BINOCULAR CONVERGENCE; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; COHORT ANALYSIS; HEAD AND NECK CANCER; HISTOPATHOLOGY; HUMAN; MATHEMATICAL ANALYSIS; MORTALITY; NASOPHARYNX CANCER; NORMAL DISTRIBUTION; OVERALL SURVIVAL; POWER ANALYSIS; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPONSE ADAPTIVE RANDOMIZATION; SAMPLE SIZE; SIMULATION; SURVIVAL TIME; TREATMENT RESPONSE;

BIAS (EPIDEMIOLOGY); BIOSTATISTICS; CLINICAL TRIALS, PHASE III AS TOPIC; COMBINED MODALITY THERAPY; COMPUTER SIMULATION; HEAD AND NECK NEOPLASMS; HUMANS; MODELS, STATISTICAL; NONLINEAR DYNAMICS; RANDOM ALLOCATION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SAMPLE SIZE;

EID: 80053576723     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.4331     Document Type: Article

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