Investigating the effect of solubility and density gradients on local hydrodynamics and drug dissolution in the USP 4 dissolution apparatus

International Journal of Pharmaceutics

Volumn 419, Issue 1-2, 2011, Pages 175-185

  D'Arcy, Deirdre M ^a   Liu, Bo ^a   Corrigan, Owen I ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Computational fluid dynamics (CFD); Dissolution; Flow through dissolution apparatus; Hydrodynamics; Natural convection; USP apparatus 4

Indexed keywords

BENZOIC ACID; LACTOSE;

ARTICLE; COMPUTATIONAL FLUID DYNAMICS; DENSITY GRADIENT; DIFFUSION COEFFICIENT; DRUG SOLUBILITY; FLOW RATE; HYDRODYNAMICS; PRIORITY JOURNAL; STEADY STATE; THERMODYNAMICS;

BENZOIC ACID; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; HYDRODYNAMICS; LACTOSE; SOLUBILITY;

EID: 80053562546     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.07.048     Document Type: Article

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