Amyloid-β aggregation on model lipid membranes: An atomic force microscopy study

Journal of Alzheimer's Disease

Volumn 26, Issue 3, 2011, Pages 485-494

  Hane, Francis ^a   Drolle, Elizabeth ^a   Gaikwad, Ravi ^a   Faught, Erin ^a   Leonenko, Zoya ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

1,2 dioleoyl 3 trimethylammonium propane, DOTAP; 1,2 dioleoyl sn glycero 3 phosphocholine, DOPC; 1,2 dioleoyl sn glycero 3 phospho (1 rac glycerol), DOPG; 1,2 dipalmitoyl sn glycero 3 phosphocholine, DPPC; Alzheimer's disease; amyloid fibril formation; amyloid lipid interactions; atomic force microscopy

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 1,2 DIOLEOYLGLYCERO 3 PHOSPHOGLYCEROL; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; DIOLEOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; PHOSPHOLIPID DERIVATIVE; UNCLASSIFIED DRUG;

ADSORPTION; ALZHEIMER DISEASE; AMYLOID PLAQUE; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOACCUMULATION; ELECTRIC POTENTIAL; GEL; LIPID COMPOSITION; LIPID MEMBRANE; LIQUID; MEMBRANE MODEL; MEMBRANE STRUCTURE; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN LIPID INTERACTION; SURFACE PROPERTY;

EID: 80053551906     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-102112     Document Type: Article

References (42)

1. Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Muller-Hill B, (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733-736.
2. Kallberg Y, Gustafsson M, Persson B, Thyberg J, Johansson J (2001) Prediction of amyloid fibril-forming proteins. J Biol Chem 276, 12945-12450.
3. Carrell R (1998) Conformational changes and disease - serpins, prions and Alzheimer's. Curr Opin Struct Biol 8, 799-809.
4. Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, KleinWL(1998) Diffusible, nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A 95, 6448-6453.
5. Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489.
6. Dahlgren KN, Manelli AM, Stine WB Jr, Baker LK, Krafft GA, LaDu MJ (2002) Oligomeric and fibrillar species of Amyloid-β peptides differentially affect neuronal viability. J Biol Chem 277, 32046-32053.
7. Roher AE, Chaney MO, Kuo YM, Webster SD, Stine WB, Haverkamp LJ,Woods AS, Cotter RJ, Tuohy JM, Krafft GA, Bonnell BS, Emmerling MR (1996) Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J Biol Chem 271, 20631-20635.
8. Campioni S, Mannini B, Pensalfini A, Zampagni M, Parrini C, Evangelisti E, Relini A, Stefani M, Dobson CM, Cecchi C, Chiti F (2010) A causative link between the structure of aberrant protein oligomers and their toxicity. Nat Chem Biol 6, 140-147.
9. DobsonCM(2001) The structural basis of protein folding and its links with human disease. Phil Trans R Soc Lond B 356, 133-145.
10. Johansson J (2003) Molecular determinants for amyloid fibril formation: lessons from lung surfactant protein C. Swiss Med Wkly 133, 275-282.
11. Chiti F, Dobson CM (2006) Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem 75, 333-366.
12. Blackley HKL, Patel N, Davies MC, Roberts CJ, Tendler SJB, Wilkinson MJ, Williams PM (1999) Morphological development ofβ(1-40) amyloid fibrils. Exp Neurol 158, 437-443
13. Walsh DM, Klyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ (2002) Amyloid-β oligomers: their production, toxicity and therapeutic inhibition. Biochem Soc Trans 30, 552-557.
14. Lin H, Bhatia I, Ratneshwar LAL (2001) Amyloid β protein forms ion channels: implications for Alzheimer's disease. pathophysiology FASEB J 15, 2433-2444.
15. Quist A, Doudevski I, Lin H, Azimova R, Ng D, Frangione B, Kagan B, Ghiso J, Lal R (2005) Amyloid ion channels: A common structural link for protein-misfolding disease. Proc Natl Acad Sci U S A 102, 10427-10432.
16. Arispe N (2004) Architecture of the Alzheimer's AßP Ion Channel Pore. J Membrane Biol 197, 33-48.
17. Kremer J, Pallitto MM, Sklansky DJ, Murphy RM (2000) Correlation ofβ-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes. Biochem 39, 10309-10318.
18. Sokolov Y, Kozak J, Kayed R, Chanturiya A, Clabe C, Hall J (2006) Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure. J Gen Physiol 128, 637-647.
19. Cordy JM, Hooper NM, Turner AJ (2006) The involvement of lipid rafts in Alzheimer's disease. Mol Membr Biol 23, 111-122.
20. Sharp JS, Forrest JA, Jones RAL (2002) Surface denaturation and amyloid fibril formation of insulin at model lipid-water interfaces. Biochem 41, 15810-15819.
21. Yip CM, Elton EA, Darabie AA, Morrison MR, McLaurin J (2001) Cholesterol, a modulator of membrane-associated Aβ-fibrillogenesis and neurotoxicity. J Mol Biol 11, 723-734.
22. Choucair A, Chakrapani M, ChakravarthyB, Katsaras J, Johnston L (2007) Preferential accumulation of Aβ(1-42) on gel phase domains of lipid bilayers: an AFM and fluorescence study. Biochim Biophys Acta 1768, 146-154.
23. Neugroschl J, Sano M (2010) Current treatment and recent clinical research in Alzheimer's disease. Mt Sinai J Med 77, 3-16.
24. Curtain C, Ali F, Smith D, Bush A, Masters C, Barnham K (2003) Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid. J Biol Chem 278, 2977-2982.
25. Cruz L, Urbanc B, Borreguero JM, Lazo ND, Teplow DB, Stanley HE (2005) Solvent and mutation effects on the nucleation of amyloid-protein folding. Proc Natl Acad Sci U S A 102, 18258-18263.
26. Bokvist M, Lindström F, Watts A, Grobner G (2004) Two types of Alzheimer'sβ-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation. J Mol Biol 335, 1039-1049.
27. Maltseva E, Kerth A, Blume A, Mçhwald A, Brezesinski G (2005) Adsorption of Amyloid β (1-40) peptide at phospholipids monolayer. Chem Biol Chem 6, 1817-1824.
28. Ege C, Majewski J,Wu G, Kjaer K, Lee KY (2005) Templating effect of lipid membranes on Alzheimer's amyloid beta peptide. Chemphyschem 6, 226-229.
29. Ionov M, Klajnert B, Gardikis K, Hatziantoniou S, Palecz B, Salakhutdinov B, Cladera J, Zamaraeva M, Demetzos C, Bryszewska M (2010) Effect of amyloid beta peptides Aβ1-28 and Aβ25-40 on model lipid membranes. J Therm Anal Calorim 99, 741-747.
30. Yanagisawa K, Odaka A, Suzuki N, Ihara Y (1995) GM1 ganglioside bound Amyloid β-protein (Aβ): a possible form of preamyloid in Alzheimer's disease. Nat Med 1, 1062-1066.
31. Terzi E, Holzemann G, Seelig J (1995) Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes. J Mol Biol 252, 633-642.
32. Choo-Smith LP, Surewicz WK (1997) The interaction between Alzheimer Amyloid β (1-40) peptide and ganglioside GM1-containing membranes. FEBS Lett 402, 95-98.
33. Feigenson GW (2006) Phase behavior of lipid mixtures. Nature Chem Biol 2, 560-563.
34. Lingwood D, Simons K (2010) Lipid rafts as a membraneorganizing principle. Science 327, 46-50.
35. Koynova R, Caffrey M (2002) An index of lipid phase diagrams. Chem Phys Lipids 115, 107-219.
36. Fezoui Y, Hartley D, Harper J, Khurana R, Walsh D, Condron M, Selkoe D, Lansbury P, Fink A, Teplow D (2000) An improved method of preparing the amyloid p-protein for fibrillogenesis and neurotoxicity experiments. Amyloid: Int J Exp Clin Invest 7, 166-178.
37. Leonenko Z, Finot E, Ma H, Dahms T, Cramb D (2004) Investigation of temperature induced phase transitions in DOPC and DPPC phospholipid bilayers using emperaturecontrolled scanning force microscopy. Biophys J 86, 3783-3793.
38. LeonenkoZ, CrambD(2002) Effect ofDNAadsorption on the phase cycling of a supported phospholipid bilayer. Nanoletters 2, 305-309.
39. Seelig A (1987) Local anesthetics and pressure: a comparison of dibucaine binding to lipid monolayers and bilayers. Biochim Biophys Acta 899, 196-204.
40. Wu J, Siu SF (2002) Study ofβ-amyloid insertion into phospholipids membranes using monolayer technique. J Biol Chem 67, 1283-1288.
41. Silvius J (1982) Thermotropic phase transitions of pure lipids in model membranes and their modifications by membrane proteins. In: Lipid-Protein Interactions, John Wiley & Sons, Inc., New York.
42. Regelin A (2000) Biophysical and lipofection studies of DOTAP analogs. Biochim Biophys Acta 1464, 151-164.