Preoperative glutamine infusion improves glycemia in heart surgery patients;Infusão pré-operatória de glutamina melhora a glicemia em pacientes submetidos à cirurgia cardíaca

Acta Cirurgica Brasileira

Volumn 26, Issue SUPPL. 1, 2011, Pages 77-81

  Hissa, Miguel Nasser ^a   de Vasconcelos, Raquel Cavalcante ^a   Guimarães, Sergio Botelho ^a   Silva, Ricardo Pereira ^a   Garcia, José Huygens Parente ^a   de Vasconcelos, Paulo Roberto Leitão ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Cardiovascular surgical procedures; Coronary artery disease; Glutamine. blood glucose; Metabolism

Indexed keywords

ALANYLGLUTAMINE; GLUCOSE; INSULIN;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; EXTRACORPOREAL CIRCULATION; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEART MUSCLE REVASCULARIZATION; HUMAN; PREOPERATIVE TREATMENT; RANDOMIZED CONTROLLED TRIAL; TREATMENT RESPONSE;

EID: 80053549091     PISSN: 01028650     EISSN: 16782674     Source Type: Journal    
DOI: 10.1590/s0102-86502011000700016     Document Type: Article

References (19)

1. McMullin J, Brozek J, McDonald E, Clarke F, Jaeschke R, Heels-Ansdell D, Leppert R, Foss A, Cook D. Lowering of Glucose in Critical care: a randomized pilot trial. J Crit Care. 2007;22(2):112-8.
2. Annetta MG, Ciancia M, Soave M, Proietti R. Diabetic and nondiabetic hyperglycemia in the ICU. Curr Anaesth Critic Care. 2006;17:385-90.
3. Hansen TK, Thiel S, Wouters PJ, Christiansen JS, Van den Berghe G. Intensive insulin therapy exerts anti-inflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J Clin Endocrinol Metab. 2003;88(3):1082-8.
4. Capes SE, Dereck H, Malberg K, Gerstein HC. Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet. 2000;355(9206):773-8.
5. Bolk J, van der Ploeg T, Cornell JH, Arnold AE, Sepers J, Umans VA. Impaired glucose mechanism predicts mortality after myocardial infarction. Int J Cardiol. 2001;79(2-3):207-14.
6. van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vblasselaers D, Ferdinande P, Lauwers P, Bouillon R. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345(19):1359-67.
7. Oudemans-van Straaten HM, Bosman RJ, Treskes M, van der Spoel HJ, Zandstra DF. Plasma glutamine depletion and patient outcome in acute ICU admissions. Int Care Med. 2001;27(1):84-90.
8. Griffiths RD, Jones C, Palmer TE. Six month outcome of critically ill patients given glutamine-supplemented parenteral nutrition. Nutrition. 1997;13(4):295-302.
9. Griffiths RD, Allen KD, Andrews FJ, Jones C. Infection, multiple organ failure, and survival in the intensive care unit: influence of glutamine-supplemented parenteral nutrition on acquired infection. Nutrition. 2002;18(7-8):546-52.
10. Goeters C, Wenn A, Mertes N, Wempe C, Van Aken H, Stehle P, Bone HG. Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients. Crit Care Med. 2002;30(9):2032-7.
11. Jones C, Palmer TEA, Griffiths RD. Randomized clinical outcome study of critically ill patients given glutamine-supplemented enteral nutrition. Nutrition. 1999;15(2):108-15.
12. Khogali SE, Harper AA, Lyall JA, Rennie MJ. Effects of L-glutamine on post-ischaemic cardiac function: protection and rescue. J Mol Cell Cardiol. 1998;30(4):819-27.
13. Borel MJ, Williams PE, Jabbour K, Levenhagen D, Kaizer E, Flakoll PJ. Parenteral glutamine infusion alters insulin- mediated glucose metabolism. JPEN J Parenter Enteral Nutr. 1998;22(5):280-5.
14. Hohorst HJ. D-Glucose-6-phosphate and D-fructose-6-phosphate. Determination with glucose-6-phosphate dehydrogenase and phosphoglucose isomerase. In: Bergmeyer HU (editor). Methods of enzymatic analysis. London: Verlag Chemie, Weinheim/Academic Press; 1963. p.134-8.
15. Mathews DE. Glutamine and glutamate kinetics in humans. In: Pharmacological nutrition immune nutrition. New York: W. Zuckschwerdt Verlag; 1995. p.68-76.
16. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr. 2001;131(9 Suppl):2556S-61S.
17. Ziegler TR, Benfell K, Smith RJ, Young LS, Brown E, Ferrari-Baliviera E, Lowe DK, Wilmore DW. Safety and metabolic effects of L-glutamine administration in humans. JPEN J Parenter Enteral Nutr. 1990;14(4 Suppl):137S-46S.
18. Bakalar B, Duska F, Pachl J, Fric M, Otahal M, Pazout J, Andel M. Parenterally administered dipeptide alanyl-glutamine prevents worsening of insulin sensitivity in multiple-trauma patients. Crit Care Med. 2006;34(2):381-6.
19. Alves WF, Guimaraes SB, Vasconcelos PRC, Vasconcelos PRL de Repercussions of l-alanyl-glutamine upon the concentrations of lactate and lactate dehydrogenase (LDH) in patients with critical ischemia o lower limbs subjected to distal revascularization. Acta Cir Bras. 2003;18(3):209-14.