Protein diffusion in photopolymerized poly(ethylene glycol) hydrogel networks

Biomedical Materials

Volumn 6, Issue 5, 2011, Pages

  Engberg, Kristin ^a   Frank, Curtis W ^a  

^a Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; DIFFUSION; ETHYLENE; GELS; GLYCOLS; HYDROPHOBICITY; MOLECULAR WEIGHT; PHOTOPOLYMERIZATION; POLYETHYLENE GLYCOLS; PROTEINS;

BOVINE SERUM ALBUMINS; CONTRIBUTING FACTOR; DIACRYLATES; DIFFUSION COEFFICIENTS; FREE WATER; HORSE-RADISH PEROXIDASE; HYDRODYNAMIC DIAMETER; HYDROGEL MEMBRANE; HYDROGEL NETWORKS; IMMUNOGLOBULIN G; MACROMONOMER; MODEL PROTEINS; NETWORK COMPOSITION; NETWORK DEFECTS; ORDERS OF MAGNITUDE; PEG HYDROGEL; POLY(ETHYLENE GLYCOL) HYDROGEL; PROTEIN DIFFUSION; SOLID CONTENTS;

HYDROGELS;

BOVINE SERUM ALBUMIN; HORSERADISH PEROXIDASE; IMMUNOGLOBULIN G; MACROGOL; MACROGOL 8000; MYOGLOBIN; POLY(ETHYLENEGLYCOL)DIACRYLATE; UNCLASSIFIED DRUG; WATER; BIOMATERIAL; MACROGOL DERIVATIVE; PROTEIN;

ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; MOLECULAR WEIGHT; PARTICLE SIZE; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN POLYMERIZATION; PROTEIN TRANSPORT; WATER CONTENT; ANIMAL; ARTIFICIAL ORGAN; BIOENGINEERING; CATTLE; CHEMISTRY; CORNEA; DIFFUSION; DRUG DELIVERY SYSTEM; HYDROGEL; MATERIALS TESTING; PERMEABILITY; PHOTOCHEMISTRY;

ARMORACIA RUSTICANA; BOVINAE;

ANIMALS; ARTIFICIAL ORGANS; BIOCOMPATIBLE MATERIALS; BIOENGINEERING; CATTLE; CORNEA; DIFFUSION; DRUG DELIVERY SYSTEMS; HORSERADISH PEROXIDASE; HYDROGELS; IMMUNOGLOBULIN G; MATERIALS TESTING; MOLECULAR WEIGHT; MYOGLOBIN; PARTICLE SIZE; PERMEABILITY; PHOTOCHEMICAL PROCESSES; POLYETHYLENE GLYCOLS; PROTEINS; SERUM ALBUMIN, BOVINE;

EID: 80053544021     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/6/5/055006     Document Type: Article

References (35)

1. Hoffman A S 2002 Hydrogels for biomedical applications Adv. Drug Deliv. Rev. 54 3-12 (Pubitemid 34081178)
2. Nguyen K T and West J L 2002 Photopolymerizable hydrogels for tissue engineering applications Biomaterials 23 4307-14
3. Gupta P, Vermani K and Garg S 2002 Hydrogels: from controlled release to pH-responsive drug delivery Drug Discov. Today 7 569-79 (Pubitemid 34603648)
4. Cruise G M, Scharp D S and Hubbell J A 1998 Characterization of permeability and network structure of interfacially photopolymerized poly(ethylene glycol) diacrylate hydrogels Biomaterials 19 1287-94 (Pubitemid 28391475)
5. Merrill E W, Dennison K A and Sung C 1993 Partitioning and diffusion of solutes in hydrogels of poly(ethylene oxide) Biomaterials 14 1117-26 (Pubitemid 24061568)
6. Kofinas P, Athanassiou V and Merrill E W 1996 Hydrogels prepared by electron irradiation of poly(ethylene oxide) in water solution: unexpected dependence of cross-link density and protein diffusion coefficients on initial PEO molecular weight Biomaterials 17 1547-50 (Pubitemid 26254186)
7. Censi R, Vermonden T, van Steenbergen M J, Deschout H, Braeckmans K, De Smedt S C, van Nostrum C F, di Martino P and Hennink W E 2009 Photopolymerized thermosensitive hydrogels for tailorable diffusion-controlled protein delivery J. Control. Release 140 230-6
8. Zustiak S P, Boukari H and Leach J B 2010 Solute diffusion and interactions in cross-linked poly(ethylene glycol) hydrogels studied by fluorescence correlation spectroscopy Soft Matter 6 3609-18
9. Li R H, Altreuter D H and Gentile F T 1996 Transport characterization of hydrogel matrices for cell encapsulation Biotechnol. Bioeng. 50 365-73 (Pubitemid 26126670)
10. Burczak K, Fujisato T, Hatada M and Ikada Y 1994 Protein permeation through poly(vinyl alcohol) hydrogel membranes Biomaterials 15 231-8 (Pubitemid 24081537)
11. Peppas N A and Wright S L 1996 Solute diffusion in poly(vinyl alcohol)/poly(acrylic acid) interpenetrating networks Macromolecules 29 8798-804 (Pubitemid 126696906)
12. Peppas N A and Wright S L 1998 Drug diffusion and binding in ionizable interpenetrating networks from poly(vinyl alcohol) and poly(acrylic acid) Eur. J. Pharm. Biopharm. 46 15-29 (Pubitemid 29168532)
13. Bell C L and Peppas N A 1996 Water, solute and protein diffusion in physiologically responsive hydrogels of poly(methacrylic acid-g-ethylene glycol) Biomaterials 17 1203-18 (Pubitemid 26175597)
14. Zhang J and Peppas N A 2000 Synthesis and characterization of pH- and temperature-sensitive poly(methacrylic acid)/poly(N-isopropylacrylamide) interpenetrating polymeric networks Macromolecules 33 102-7 (Pubitemid 32212698)
15. Khoury C, Adalsteinsson T, Johnson B, Crone W C and Beebe D J 2003 Tunable microfabricated hydrogels - a study in protein interaction and diffusion Biomed. Microdevices 5 35-45 (Pubitemid 38095895)
16. Peppas N A and Reinhart C T 1983 Solute diffusion in swollen membranes: part I. A new theory J. Membr. Sci. 15 275-87 (Pubitemid 14243473)
17. Reinhart C T and Peppas N A 1984 Solute diffusion in swollen membranes. Part II. Influence of crosslinking on diffusive properties J. Membr. Sci. 18 227-39
18. Gong J P, Katsuyama Y, Kurokawa T and Osada Y 2003 Double-network hydrogels with extremely high mechanical strength Adv. Mater. 15 1155-8
19. Myung D, Koh W, Ko J, Hu Y, Carrasco M, Noolandi J, Ta C N and Frank C W 2007 Biomimetic strain hardening in interpenetrating polymer network hydrogels Polymer 48 5376-87 (Pubitemid 47247467)
20. Myung D et al 2007 Design and fabrication of an artificial cornea based on a photolithographically patterned hydrogel construct Biomed. Microdevices 9 911-22 (Pubitemid 350020687)
21. Myung D, Farooqui N, Zheng L L, Koh W, Gupta S, Bakri A, Noolandi J, Cochran J R, Frank C W and Ta C N 2009 Bioactive interpenetrating polymer network hydrogels that support corneal epithelial wound healing J. Biomed. Mater. Res. A 90A 70-81
22. Myung D, Farooqui N, Waters D, Schaber S, Koh W, Carrasco M, Noolandi J, Frank C W and Ta C N 2008 Glucose-permeable interpenetrating polymer network hydrogels for corneal implant applications: a pilot study Curr. Eye Res. 33 29-43 (Pubitemid 351156954)
23. Yim E S, Zhao B, Myung D, Kourtis L C, Frank C W, Carter D, Smith R L and Goodman S B 2009 Biocompatibility of poly(ethylene glycol)/poly(acrylic acid) interpenetrating polymer network hydrogel particles in RAW 264.7 macrophage and MG-63 osteoblast cell lines J. Biomed. Mater. Res. A 91A 894-902
24. Waters D J and Frank C W 2009 Hindered diffusion of oligosaccharides in high strength poly(ethylene glycol)/poly(acrylic acid) interpenetrating network hydrogels: hydrodynamic versus obstruction models Polymer 50 6331-9
25. Sweeney D F, Xie R Z, O'Leary D J, Vannas A, Odell R, Schindhelm K, Cheng H Y, Steele J G and Holden B A 1998 Nutritional requirements of the corneal epithelium and anterior stroma: clinical findings Invest. Ophthalmol. Vis. Sci. 39 284-91 (Pubitemid 28093863)
26. Bonincontro A, Bultrini E, Calandrini V and Onori G 2001 Conformational changes of proteins in aqueous solution induced by temperature in the pre-melting region Phys. Chem. Chem. Phys. 3 3811-3 (Pubitemid 32885546)
27. Axelsson I 1978 Characterization of proteins and other macromolecules by agarose gel chromatography J. Chromatogr. A 152 21-32 (Pubitemid 8331723)
28. Stenekes R J H, De Smedt S C, Demeester J, Sun G, Zhang Z and Hennink W E 2000 Pore sizes in hydrated dextran microspheres Biomacromolecules 1 696-703
29. Lee C J, Vroom J A, Fishman H A and Bent S F 2006 Determination of human lens capsule permeability and its feasibility as a replacement for Bruch's membrane Biomaterials 27 1670-8 (Pubitemid 41739593)
30. Waters D J, Engberg K, Parke-Houben R, Hartmann L, Ta C N, Toney M F and Frank C W 2010 Morphology of photopolymerized end-linked poly(ethylene glycol) hydrogels by small-angle X-ray scattering Macromolecules 43 6861-70
31. Scott R A and Peppas N A 1999 Highly crosslinked, PEG-containing copolymers for sustained solute delivery Biomaterials 20 1371-80 (Pubitemid 29326807)
32. Cho N J, Elazar M, Xiong A, Lee W, Chiao E, Baker J, Frank C W and Glenn J S 2009 Viral infection of human progenitor and liver-derived cells encapsulated in three-dimensional PEG-based hydrogel Biomed. Mater. 4 011001
33. Lee W, Cho N J, Xiong A, Glenn J S and Frank C W 2010 Hydrophobic nanoparticles improve permeability of cell-encapsulating poly(ethylene glycol) hydrogels while maintaining patternability Proc.Natl. Acad. Sci. USA 107 20709-14
34. Charalel R A, Engberg K, Noolandi J, Cochran J R, Frank C W and Ta C N 2010 Diffusion of protein through the human cornea Ophthalmic Res. in press
35. Ottinger M, Thiel M A, Feige U, Lichtlen P and Urech D M 2009 Efficient intraocular penetration of topical anti-TNF-α single-chain antibody (ESBA105) to anterior and posterior segment without penetration enhancer Invest. Ophthalmol. Vis. Sci. 50 779-86