메뉴 건너뛰기




Volumn 352, Issue 1, 2011, Pages 27-42

Clinical experience with recombinant molecules for allergy vaccination

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; BINDING PROTEIN; BIRCH POLLEN ALLERGEN; BIRCH POLLEN EXTRACT; GAMMA INTERFERON; GRASS POLLEN ALLERGEN; IMMUNOGLOBULIN E ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MODULAR ANTIGEN TRANSLOCATION FEL D 1; NATURAL ALLERGEN; PLACEBO; POLLEN ANTIGEN; RAGWEED AMB A 1; RECOMBINANT ALLERGEN; RECOMBINANT BET V 1; RECOMBINANT BET V 1 FRAGMENT; RECOMBINANT BET V 1 FV; RECOMBINANT BET V 1 TRIMER; RECOMBINANT CAT ALLERGEN FEL D 1; TOLL LIKE RECEPTOR 9; TRANSACTIVATOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ALUMINUM HYDROXIDE; BET V 1; BET V 1A FRAGMENT; BET V 1A TRIMER; FEL D 1; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G4; INTERLEUKIN 12; PHL P 1; PHL P 2; PHL P 5A; PHL P 5B; PHL P 6;

EID: 80053514862     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/82_2011_129     Document Type: Article
Times cited : (10)

References (49)
  • 1
    • 0034925159 scopus 로고    scopus 로고
    • Bypassing IgE and targeting T cells for specific immunotherapy of allergy
    • DOI 10.1016/S1471-4906(01)01862-2, PII S1471490601018622
    • Akdis CA, Blaser K (2001) Bypassing IgE and targeting T cells for specific immunotherapy of allergy. Trends Immunol 22:175-178 (Pubitemid 32673650)
    • (2001) Trends in Immunology , vol.22 , Issue.4 , pp. 175-178
    • Akdis, C.A.1    Blaser, K.2
  • 6
    • 0023766881 scopus 로고
    • Isolation and characterization of messenger RNA from male inflorescences and pollen of the white birch (Betula verrucosa
    • Breiteneder H, Hassfeld W, Pettenburger K et al (1988) Isolation and characterization of messenger RNA from male inflorescences and pollen of the white birch (Betula verrucosa). Int Arch Allergy Appl Immunol 87:19-24
    • (1988) Int Arch Allergy Appl Immunol , vol.87 , pp. 19-24
    • Breiteneder, H.1    Hassfeld, W.2    Pettenburger, K.3
  • 8
    • 0026507386 scopus 로고
    • Bee venom phospholipase A2-specific T cell clones from human allergic and non-allergic individuals: Cytokine patterns change in response to the antigen concentration
    • Carballido JM, Carballido-Perrig N, Terres G et al (1992) Bee venom phospholipase A2-specific T cell clones from human allergic and non-allergic individuals: cytokine patterns change in response to the antigen concentration. Eur J Immunol 22:1357-1363
    • (1992) Eur J Immunol , vol.22 , pp. 1357-1363
    • Carballido, J.M.1    Carballido-Perrig, N.2    Terres, G.3
  • 11
    • 39149127957 scopus 로고    scopus 로고
    • Sublingual grass allergen tablet immunotherapy provides sustained clinical benefit with progressive immunologic changes over 2 years
    • Dahl R, Kapp A, Colombo G et al (2008) Sublingual grass allergen tablet immunotherapy provides sustained clinical benefit with progressive immunologic changes over 2 years. J Allergy Clin Immunol 121:512-518
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 512-518
    • Dahl, R.1    Kapp, A.2    Colombo, G.3
  • 14
    • 31944443997 scopus 로고    scopus 로고
    • Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis
    • DOI 10.1016/j.jaci.2005.11.014, PII S0091674905025339
    • Frew AJ, Powell RJ, Corrigan CJ, Durham SR (2006) Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinocon-junctivitis. J Allergy Clin Immunol 117:319-325 (Pubitemid 43190146)
    • (2006) Journal of Allergy and Clinical Immunology , vol.117 , Issue.2 , pp. 319-325
    • Frew, A.J.1    Powell, R.J.2    Corrigan, C.J.3    Durham, S.R.4
  • 17
    • 67649432626 scopus 로고    scopus 로고
    • Extensive IgE cross-reactivity towards the Pooideae grasses substantiated for a large number of grass-pollen-sensitized subjects
    • Johansen N, Weber RW, Ipsen H et al (2009) Extensive IgE cross-reactivity towards the Pooideae grasses substantiated for a large number of grass-pollen-sensitized subjects. Int Arch Allergy Immunol 150:325-334
    • (2009) Int Arch Allergy Immunol , vol.150 , pp. 325-334
    • Johansen, N.1    Weber, R.W.2    Ipsen, H.3
  • 18
    • 0026028924 scopus 로고
    • Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis
    • Juniper EF, Guyatt GH (1991) Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis. Clin Exp Allergy 21:77-83
    • (1991) Clin Exp Allergy , vol.21 , pp. 77-83
    • Juniper, E.F.1    Guyatt, G.H.2
  • 21
    • 33646532382 scopus 로고    scopus 로고
    • Evaluation of the allergenicity of hypoallergenic recombinant derivatives of Bet v 1 using basophil activation vy CD203c expression measurement
    • Marone G (ed) JGC Editions, Naples
    • Kahlert H, Weber B, Cromwell O, Fiebig H (2003) Evaluation of the allergenicity of hypoallergenic recombinant derivatives of Bet v 1 using basophil activation vy CD203c expression measurement. In: Marone G (ed) Clinical immunology and allergy in medicine. JGC Editions, Naples, pp 735-740
    • (2003) Clinical Immunology and Allergy in Medicine , pp. 735-740
    • Kahlert, H.1    Weber, B.2    Cromwell, O.3    Fiebig, H.4
  • 23
    • 77954474966 scopus 로고    scopus 로고
    • Specific immunotherapy with recombinant birch pollen allergen rBet v1-FV results of 2 years of treatment (Phase II trial
    • (Abstract)
    • Kettner J, Meyer H, Cromwell O et al (2007a) Specific immunotherapy with recombinant birch pollen allergen rBet v1-FV results of 2 years of treatment (Phase II trial). Allergy 62(Suppl. 83): 262 (Abstract)
    • (2007) Allergy , vol.62 , Issue.SUPPL. 83 , pp. 262
    • Kettner, J.1    Meyer, H.2    Cromwell, O.3
  • 24
    • 76949102610 scopus 로고    scopus 로고
    • Specific immunotherapy with recombinant birch pollen allergen rBet v 1-FV is clinically efficacious-results of a phase III study
    • (Abstract)
    • Kettner J, Meyer H, Narkus A et al (2007b) Specific immunotherapy with recombinant birch pollen allergen rBet v 1-FV is clinically efficacious-results of a phase III study. Allergy 62(Suppl 83):33 (Abstract)
    • (2007) Allergy , vol.62 , Issue.SUPPL. 83 , pp. 33
    • Kettner, J.1    Meyer, H.2    Narkus, A.3
  • 25
    • 27144509153 scopus 로고    scopus 로고
    • Specific immunotherapy with recombinant birch pollen allergen rBet v1-FV is clinically efficacious
    • (Abstract)
    • Klimek L, Bachert C, Doemer C et al (2005) Specific immunotherapy with recombinant birch pollen allergen rBet v1-FV is clinically efficacious. Allergy Clin Immunol Int. Suppl 1:15 (Abstract)
    • (2005) Allergy Clin Immunol Int , Issue.SUPPL. 1 , pp. 15
    • Klimek, L.1    Bachert, C.2    Doemer, C.3
  • 26
    • 33749016485 scopus 로고    scopus 로고
    • Immunological mechanisms of allergen-specific immunotherapy
    • DOI 10.1038/nri1934, PII NRI1934
    • Larche M, Akdis CA, Valenta R (2006) Immunological mechanisms of allergen-specific immunotherapy. Nat Rev Immunol 6:761-771 (Pubitemid 44453462)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.10 , pp. 761-771
    • Larche, M.1    Akdis, C.A.2    Valenta, R.3
  • 27
    • 0023286915 scopus 로고
    • Standardized extracts: Modified allergens-Allergoids
    • Maasch HJ, Marsh DG (1987) Standardized extracts: Modified allergens-Allergoids. Clin Rev Allergy 5:89-106
    • (1987) Clin Rev Allergy , vol.5 , pp. 89-106
    • Maasch, H.J.1    Marsh, D.G.2
  • 28
    • 58149136998 scopus 로고    scopus 로고
    • Targeting the MHC class II pathway of antigen presentation enhances immunogenicity and safety of allergen immunotherapy
    • Martinez-Gomez JM, Johansen P, Rose H et al (2009) Targeting the MHC class II pathway of antigen presentation enhances immunogenicity and safety of allergen immunotherapy. Allergy 64:172-178
    • (2009) Allergy , vol.64 , pp. 172-178
    • Martinez-Gomez, J.M.1    Johansen, P.2    Rose, H.3
  • 29
    • 0036240589 scopus 로고    scopus 로고
    • Development of new IgE specificities to allergenic components in birch pollen extract during specific immunotherapy studied with immunoblotting and Pharmacia CAP System™
    • DOI 10.1034/j.1398-9995.2002.13248.x
    • Moverare R, Elfman L, Vesterinen E et al (2002) Development of new IgE specificities to allergenic components in birch pollen extract during specific immunotherapy studied with immunoblotting and Pharmacia CAP System. Allergy 57:423-430 (Pubitemid 34442156)
    • (2002) Allergy: European Journal of Allergy and Clinical Immunology , vol.57 , Issue.5 , pp. 423-430
    • Moverare, R.1    Elfman, L.2    Vesterinen, E.3    Metso, T.4    Haahtela, T.5
  • 30
    • 77957666628 scopus 로고    scopus 로고
    • Clinical trials with recombinant allergens-three perspectives: Industry
    • Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe
    • Narkus A, Kniest F, Menzel A et al. (2009) Clinical trials with recombinant allergens-three perspectives: industry. Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe. Frankfurt AM 96:270-278
    • (2009) Frankfurt AM , vol.96 , pp. 270-278
    • Narkus, A.1    Kniest, F.2    Menzel, A.3
  • 31
    • 33646471148 scopus 로고    scopus 로고
    • Molecular approaches for new vaccines against allergy
    • Niederberger V, Valenta R (2006) Molecular approaches for new vaccines against allergy. Expert Rev Vaccines 5:103-110
    • (2006) Expert Rev Vaccines , vol.5 , pp. 103-110
    • Niederberger, V.1    Valenta, R.2
  • 33
    • 34047152536 scopus 로고    scopus 로고
    • Vaccination with genetically modified birch pollen allergens: Immune and clinical effects on oral allergy syndrome
    • Niederberger V, Reisinger J, Valent P et al (2007) Vaccination with genetically modified birch pollen allergens: Immune and clinical effects on oral allergy syndrome. J Allergy Clin Immunol 119:1013-1019
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1013-1019
    • Niederberger, V.1    Reisinger, J.2    Valent, P.3
  • 34
    • 0013687727 scopus 로고    scopus 로고
    • Comparison of genetically engineered hypoallergenic rBet v 1 derivatives with rBet v 1 wild-type by skin prick and intradermal testing: Results obtained in a french population
    • DOI 10.1046/j.1365-2222.2000.00869.x
    • Pauli G, Purohit A, Oster JP et al (2000) Comparison of genetically engineered hypoallergenic rBet v 1 derivatives with rBet v 1 wild-type by skin prick and intradermal testing: results obtained in a French population. Clin Exp Allergy 30:1076-1084 (Pubitemid 30619760)
    • (2000) Clinical and Experimental Allergy , vol.30 , Issue.8 , pp. 1076-1084
    • Pauli, G.1    Purohit, A.2    Oster, J.-P.3    De Blay, F.4    Vrtala, S.5    Niederberger, V.6    Kraft, D.7    Valenta, R.8
  • 35
    • 49149107253 scopus 로고    scopus 로고
    • Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis
    • Pauli G, Larsen TH, Rak S et al (2008) Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis. J Allergy Clin Immunol 122:951-960
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 951-960
    • Pauli, G.1    Larsen, T.H.2    Rak, S.3
  • 36
    • 46849121475 scopus 로고    scopus 로고
    • Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives
    • Purohit A, Niederberger V, Kronqvist M et al (2008) Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives. Clin Exp Allergy 38: 1514-1525
    • (2008) Clin Exp Allergy , vol.38 , pp. 1514-1525
    • Purohit, A.1    Niederberger, V.2    Kronqvist, M.3
  • 37
    • 0028889780 scopus 로고
    • Genetic detoxification of bacterial toxins: A new approach to vaccine development
    • Rappuoli R, Douce G, Dougan G, Pizza M (1995) Genetic detoxification of bacterial toxins: a new approach to vaccine development. Int Arch Allergy Immunol 108:327-333
    • (1995) Int Arch Allergy Immunol , vol.108 , pp. 327-333
    • Rappuoli, R.1    Douce, G.2    Dougan, G.3    Pizza, M.4
  • 39
    • 0033949795 scopus 로고    scopus 로고
    • The antigen dose determines T helper subset development by regulation of CD40 ligand
    • DOI 10.1002/1521-4141(200007)30:7<2056::AID-IMMU2056>3.0.CO;2-S
    • Ruedl C, Bachmann MF, Kopf M (2000) The antigen dose determines T helper cell subset development by regulation of CD40 ligand. Eur J Immunol 30:2056-2064 (Pubitemid 30456202)
    • (2000) European Journal of Immunology , vol.30 , Issue.7 , pp. 2056-2064
    • Ruedl, C.1    Bachmann, M.F.2    Kopf, M.3
  • 40
    • 70350764362 scopus 로고    scopus 로고
    • Intralymphatic allergen specific immunotherapy using modified recombinant allergen targeting the MHC class II pathway: A double-blind placebo-controlled clinical trial in cat dander allergic patients
    • (Abstract)
    • Senti G, Kuster D, Martinez-Gomez JM et al (2009) Intralymphatic allergen specific immunotherapy using modified recombinant allergen targeting the MHC class II pathway: a double-blind placebo-controlled clinical trial in cat dander allergic patients. Allergy 64(Suppl 90):74 (Abstract)
    • (2009) Allergy , vol.64 , Issue.SUPPL. 90 , pp. 74
    • Senti, G.1    Kuster, D.2    Martinez-Gomez, J.M.3
  • 41
    • 80053542650 scopus 로고    scopus 로고
    • Safety and efficacy of recombinant grass pollen allergens: A dose-response study
    • [Abstract]
    • Sprung V, Pfaar O, Klimek L et al (2009) Safety and efficacy of recombinant grass pollen allergens: a dose-response study. Allergy 64(Suppl 90):147 [Abstract]
    • (2009) Allergy , vol.64 , Issue.SUPPL. 90 , pp. 147
    • Sprung, V.1    Pfaar, O.2    Klimek, L.3
  • 45
    • 0032739068 scopus 로고    scopus 로고
    • Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: Results obtained with a mix of two recombinant Bet v 1 fragments and recombinant Bet v 1 trimer in a Swedish population before the birch pollen season
    • DOI 10.1016/S0091-6749(99)70077-1
    • Van Hage-Hamsten M, Kronqvist M, Zetterström O et al (1999) Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: results obtained with a mix of two recombinant Bet v 1 fragments and recombinant Bet v 1 trimer in a Swedish population before the birch pollen season. J Allergy Clin Immunol 104:969-977 (Pubitemid 29532117)
    • (1999) Journal of Allergy and Clinical Immunology , vol.104 , Issue.5 , pp. 969-977
    • Van Hage-Hamsten, M.1    Kronqvist, M.2    Zetterstrom, O.3    Johansson, E.4    Niederberger, V.5    Vrtala, S.6    Gronlund, H.7    Gronneberg, R.8    Valenta, R.9
  • 47
    • 0034544450 scopus 로고    scopus 로고
    • T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies
    • Vrtala S, Akdis CA, Budak F et al (2001a) T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies. J Immunol 165:6653-6659
    • (2001) J Immunol , vol.165 , pp. 6653-6659
    • Vrtala, S.1    Akdis, C.A.2    Budak, F.3
  • 48
    • 0035462111 scopus 로고    scopus 로고
    • Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen, Bet v 1
    • Vrtala S, Hirtenlehner K, Susani M et al (2001b) Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen, Bet v 1. FASEB J 15:2045-2047
    • (2001) FASEB J , vol.15 , pp. 2045-2047
    • Vrtala, S.1    Hirtenlehner, K.2    Susani, M.3
  • 49
    • 0037756777 scopus 로고    scopus 로고
    • Size exclusion chromatography as a tool for quality control of recombinant allergens and hypoallergenic variants
    • DOI 10.1016/S0165-022X(03)00060-5
    • Weber B, Slamal H, Suck R (2003) Size exclusion chromatography as a tool for quality control of recombinant allergens and hypoallergenic variants. J Biochem Biophys Meth 56:219-232 (Pubitemid 36776603)
    • (2003) Journal of Biochemical and Biophysical Methods , vol.56 , Issue.1-3 , pp. 219-232
    • Weber, B.1    Slamal, H.2    Suck, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.