-
1
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
DOI 10.1007/s00401-007-0243-4
-
Louis DN, Ohgaki H, Wiestler OD, etal: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114: 97-109, 2007. (Pubitemid 47103521)
-
(2007)
Acta Neuropathologica
, vol.114
, Issue.2
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
Scheithauer, B.W.7
Kleihues, P.8
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp R, Mason WP, Van den Bent MJ, etal: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996, 2005. (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den, B.M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
3
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY and Kesari S: Malignant gliomas in adults. N Engl J Med 359: 492-507, 2008.
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
4
-
-
58149471244
-
Epidemiology of brain tumors
-
Ohgaki H: Epidemiology of brain tumors. Methods Mol Biol 472: 323-342, 2009.
-
(2009)
Methods Mol Biol
, vol.472
, pp. 323-342
-
-
Ohgaki, H.1
-
5
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, Shu HK, WenPY and Olson JJ: Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 60: 166-193, 2010.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 166-193
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
Shu, H.K.4
Wen, P.Y.5
Olson, J.J.6
-
6
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, etal: An integrated genomic analysis of human glioblastoma multiforme. Science 321: 1807-1812, 2008.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
7
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C and Von DeimlingA: Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol 116: 597-602, 2008.
-
(2008)
Acta Neuropathol
, vol.116
, pp. 597-602
-
-
Balss, J.1
Meyer, J.2
Mueller, W.3
Korshunov, A.4
Hartmann, C.5
Von Deimling, A.6
-
8
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas
-
Hartmann C, Meyer J, Balss J, etal: Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. Acta Neuropathol 118: 469-474, 2009.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
-
9
-
-
68349116524
-
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
-
Ichimura K, Pearson DM, Kocialkowski S, etal: IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas. Neuro Oncol 11: 341-347, 2009.
-
(2009)
Neuro Oncol
, vol.11
, pp. 341-347
-
-
Ichimura, K.1
Pearson, D.M.2
Kocialkowski, S.3
-
10
-
-
65349150503
-
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
-
Watanabe T, Nobusawa S, Kleihues P and Ohgaki H: IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol 174: 1149-1153, 2009.
-
(2009)
Am J Pathol
, vol.174
, pp. 1149-1153
-
-
Watanabe, T.1
Nobusawa, S.2
Kleihues, P.3
Ohgaki, H.4
-
11
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G, etal: IDH1 and IDH2 mutations in gliomas. N Engl J Med 360: 765-773, 2009.
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
-
13
-
-
70249097408
-
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
-
Sanson M, Marie Y, Paris S, etal: Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 27: 4150-4154, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4150-4154
-
-
Sanson, M.1
Marie, Y.2
Paris, S.3
-
14
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S, etal: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462: 739-744, 2009.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
15
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR, etal: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 17: 225-234, 2010.
-
(2010)
Cancer Cell
, vol.17
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
-
16
-
-
77649122144
-
IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: A report of the European Organization for Research and Treatment of Cancer Brain Tumor Group
-
Van den Bent MJ, Dubbink HJ, Marie Y, etal: IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group. Clin Cancer Res 16: 1597-1604, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1597-1604
-
-
Van Den Bent, M.J.1
Dubbink, H.J.2
Marie, Y.3
-
17
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
Wick W, Hartmann C, Engel C, etal: NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol 27: 5874-5880, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
-
18
-
-
73349108806
-
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide
-
Dubbink HJ, Taal W, Van Marion R, etal: IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide. Neurology 73: 1792-1795, 2009.
-
(2009)
Neurology
, vol.73
, pp. 1792-1795
-
-
Dubbink, H.J.1
Taal, W.2
Van Marion, R.3
-
19
-
-
78149249554
-
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
-
Houillier C, Wang X, Kaloshi G, etal: IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas. Neurology 75: 1560-1566, 2010.
-
(2010)
Neurology
, vol.75
, pp. 1560-1566
-
-
Houillier, C.1
Wang, X.2
Kaloshi, G.3
-
20
-
-
34250658870
-
High-resolution DNA melting analysis for simple and efficient molecular diagnostics
-
DOI 10.2217/14622416.8.6.597
-
Reed GH, Kent JO and Wittwer CT: High-resolution DNA melting analysis for simple and efficient molecular diagnostics. Pharmacogenomics 8: 597-608, 2007. (Pubitemid 46939585)
-
(2007)
Pharmacogenomics
, vol.8
, Issue.6
, pp. 597-608
-
-
Reed, G.H.1
Kent, J.O.2
Wittwer, C.T.3
-
21
-
-
0025281789
-
Response criteria for phase II studies of supratentorial malignant glioma
-
Macdonald DR, Cascino TL, Schold SJ and CairncrossJG: Response criteria for phase II studies of supratentorial malignant glioma. J Clin Oncol 8: 1277-1280, 1990. (Pubitemid 20195640)
-
(1990)
Journal of Clinical Oncology
, vol.8
, Issue.7
, pp. 1277-1280
-
-
Macdonald, D.R.1
Cascino, T.L.2
Schold Jr., S.C.3
Cairncross, J.G.4
-
22
-
-
74049087788
-
Pseudoprogression and pseudoresponse in the treatment of gliomas
-
Brandsma D and Van den Bent MJ: Pseudoprogression and pseudoresponse in the treatment of gliomas. Curr Opin Neurol 22: 633-638, 2009.
-
(2009)
Curr Opin Neurol
, vol.22
, pp. 633-638
-
-
Brandsma, D.1
Van Den Bent, M.J.2
-
23
-
-
68349088073
-
Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma
-
Korshunov A, Meyer J, Capper D, etal: Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma. Acta Neuropathol 118: 401-405, 2009.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 401-405
-
-
Korshunov, A.1
Meyer, J.2
Capper, D.3
-
24
-
-
73349109131
-
Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues
-
Horbinski C, Kofler J, Kelly LM, Murdoch GH and Nikiforova MN: Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues. J Neuropathol Exp Neurol 68: 1319-1325, 2009.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 1319-1325
-
-
Horbinski, C.1
Kofler, J.2
Kelly, L.M.3
Murdoch, G.H.4
Nikiforova, M.N.5
-
25
-
-
58349111311
-
IDH1 mutations at residue p.R132 [IDH1(R132)] occur frequently in high-grade gliomas but not in other solid tumors
-
Bleeker FE, Lamba S, Leenstra S, etal: IDH1 mutations at residue p.R132 [IDH1(R132)] occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat 30: 7-11, 2009.
-
(2009)
Hum Mutat
, vol.30
, pp. 7-11
-
-
Bleeker, F.E.1
Lamba, S.2
Leenstra, S.3
-
26
-
-
78149466021
-
IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders
-
Zou Y, Zeng Y, Zhang DF, Zou SH, Cheng YF and Yao YG: IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders. Biochem Biophys Res Commun 402: 378-383, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.402
, pp. 378-383
-
-
Zou, Y.1
Zeng, Y.2
Zhang, D.F.3
Zou, S.H.4
Cheng, Y.F.5
Yao, Y.G.6
-
27
-
-
77956265489
-
IDH mutations in glioma and acute myeloid leukemia
-
Dang L, Jin S and Su SM: IDH mutations in glioma and acute myeloid leukemia. Trends Mol Med 16: 387-397, 2010.
-
(2010)
Trends Mol Med
, vol.16
, pp. 387-397
-
-
Dang, L.1
Jin, S.2
Su, S.M.3
-
28
-
-
78649990315
-
Cancer-associated IDH mutations: Biomarker and therapeutic opportunities
-
Yen KE, Bittinger MA, Su SM and Fantin VR: Cancer-associated IDH mutations: biomarker and therapeutic opportunities. Oncogene 29: 6409-6417, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 6409-6417
-
-
Yen, K.E.1
Bittinger, M.A.2
Su, S.M.3
Fantin, V.R.4
-
30
-
-
78951489314
-
IDH1 mutations are common in malignant gliomas arising in adolescents: A report from the Children's Oncology Group
-
Pollack IF, Hamilton RL, Sobol RW, etal: IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group. Childs Nerv Syst 27: 87-94, 2011.
-
(2011)
Childs Nerv Syst
, vol.27
, pp. 87-94
-
-
Pollack, I.F.1
Hamilton, R.L.2
Sobol, R.W.3
-
31
-
-
77149152775
-
Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma
-
Gravendeel LA, Kloosterhof NK, Bralten LB, etal: Segregation of non-p.R132H mutations in IDH1 in distinct molecular subtypes of glioma. Hum Mutat 31: E1186-E1199, 2010.
-
(2010)
Hum Mutat
, vol.31
-
-
Gravendeel, L.A.1
Kloosterhof, N.K.2
Bralten, L.B.3
-
32
-
-
70349594347
-
Analysis of IDH1 and IDH2 mutations in Japanese glioma patients
-
Sonoda Y, Kumabe T, Nakamura T, etal: Analysis of IDH1 and IDH2 mutations in Japanese glioma patients. Cancer Sci 100: 1996-1998, 2009.
-
(2009)
Cancer Sci
, vol.100
, pp. 1996-1998
-
-
Sonoda, Y.1
Kumabe, T.2
Nakamura, T.3
-
33
-
-
78651082266
-
Patients with IDH1 wild-type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
-
Hartmann C, Hentschel B, Wick W, etal: Patients with IDH1 wild-type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol 120: 707-718, 2010.
-
(2010)
Acta Neuropathol
, vol.120
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
-
34
-
-
70349653793
-
IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
-
Nobusawa S, Watanabe T, Kleihues P and Ohgaki H: IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res 15: 6002-6007, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6002-6007
-
-
Nobusawa, S.1
Watanabe, T.2
Kleihues, P.3
Ohgaki, H.4
-
35
-
-
78651067051
-
Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis
-
Metellus P, Coulibaly B, Colin C, etal: Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis. Acta Neuropathol 120: 719-729, 2010.
-
(2010)
Acta Neuropathol
, vol.120
, pp. 719-729
-
-
Metellus, P.1
Coulibaly, B.2
Colin, C.3
-
36
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
DOI 10.1056/NEJMoa043331
-
Hegi ME, Diserens AC, Gorlia T, etal: MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352: 997-1003, 2005. (Pubitemid 40349502)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.-C.2
Gorlia, T.3
Hamou, M.-F.4
De Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.C.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
37
-
-
33749075532
-
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03
-
DOI 10.1200/JCO.2006.06.9104
-
Herrlinger U, Rieger J, Koch D, etal: Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03. J Clin Oncol 24: 4412-4417, 2006. (Pubitemid 46630979)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.27
, pp. 4412-4417
-
-
Herrlinger, U.1
Rieger, J.2
Koch, D.3
Loeser, S.4
Blaschke, B.5
Kortmann, R.-D.6
Steinbach, J.P.7
Hundsberger, T.8
Wick, W.9
Meyermann, R.10
Tan, T.-C.11
Sommer, C.12
Bamberg, M.13
Reifenberger, G.14
Weller, M.15
-
38
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the German Glioma Network
-
Weller M, Felsberg J, Hartmann C, etal: Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol 27: 5743-5750, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Hartmann, C.3
-
39
-
-
77955508065
-
Glioma-derived mutations in IDH: From mechanism to potential therapy
-
Fu Y, Huang R, Du J, Yang R, An N and Liang A: Glioma-derived mutations in IDH: from mechanism to potential therapy. Biochem Biophys Res Commun 397: 127-130, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.397
, pp. 127-130
-
-
Fu, Y.1
Huang, R.2
Du, J.3
Yang, R.4
An, N.5
Liang, A.6
-
40
-
-
77951580527
-
Gene expression profiling predicts response to temozolomide in malignant gliomas
-
Yoshino A, Ogino A, Yachi K, etal: Gene expression profiling predicts response to temozolomide in malignant gliomas. Int J Oncol 36: 1367-1377, 2010.
-
(2010)
Int J Oncol
, vol.36
, pp. 1367-1377
-
-
Yoshino, A.1
Ogino, A.2
Yachi, K.3
|