메뉴 건너뛰기




Volumn 74, Issue 5, 2011, Pages 496-501

A Variant of the Il2ra/Cd25 Gene Predisposing to Graves' Disease is Associated with Increased Levels of Soluble Interleukin-2 Receptor

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2 RECEPTOR ALPHA; SOLUBLE INTERLEUKIN 2 RECEPTOR;

EID: 80053494417     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2011.02608.x     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 70449707736 scopus 로고    scopus 로고
    • Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population
    • Kurreeman FA, Daha NA, Chang M et al. Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population. Ann Rheum Dis 2009;68:1789-90.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1789-1790
    • Kurreeman, F.A.1    Daha, N.A.2    Chang, M.3
  • 2
    • 77952888454 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
    • Stahl EA, Raychaudhuri S, Remmers EF et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 2010;42:508-14.
    • (2010) Nat Genet , vol.42 , pp. 508-514
    • Stahl, E.A.1    Raychaudhuri, S.2    Remmers, E.F.3
  • 3
    • 58249113834 scopus 로고    scopus 로고
    • Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis
    • Hinks A, Ke X, Barton A et al. Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis. Arthritis Rheum 2009;60:251-7.
    • (2009) Arthritis Rheum , vol.60 , pp. 251-257
    • Hinks, A.1    Ke, X.2    Barton, A.3
  • 4
    • 34249030885 scopus 로고    scopus 로고
    • IL2RA/CD25 polymorphisms contribute to multiple sclerosis susceptibility
    • Matesanz F, Caro-Maldonado A, Fedetz M et al. IL2RA/CD25 polymorphisms contribute to multiple sclerosis susceptibility. J Neurol 2007;254:682-4.
    • (2007) J Neurol , vol.254 , pp. 682-684
    • Matesanz, F.1    Caro-Maldonado, A.2    Fedetz, M.3
  • 5
    • 42549108701 scopus 로고    scopus 로고
    • IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations
    • Weber F, Fontaine B, Cournu-Rebeix I et al. IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations. Genes Immun 2008;9:259-63.
    • (2008) Genes Immun , vol.9 , pp. 259-263
    • Weber, F.1    Fontaine, B.2    Cournu-Rebeix, I.3
  • 6
    • 20244373351 scopus 로고    scopus 로고
    • Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms
    • Vella A, Cooper JD, Lowe CE et al. Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet 2005;76:773-9.
    • (2005) Am J Hum Genet , vol.76 , pp. 773-779
    • Vella, A.1    Cooper, J.D.2    Lowe, C.E.3
  • 7
    • 34548367511 scopus 로고    scopus 로고
    • Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    • Lowe CE, Cooper JD, Brusko T et al. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nat Genet 2007;39:1074-82.
    • (2007) Nat Genet , vol.39 , pp. 1074-1082
    • Lowe, C.E.1    Cooper, J.D.2    Brusko, T.3
  • 8
    • 59249087219 scopus 로고    scopus 로고
    • IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D)
    • Alcina A, Fedetz M, Ndagire D et al. IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D). PLoS ONE 2009;4:e4137.
    • (2009) PLoS ONE , vol.4
    • Alcina, A.1    Fedetz, M.2    Ndagire, D.3
  • 9
    • 33947274768 scopus 로고    scopus 로고
    • Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs
    • Brand OJ, Heward JM, Franklyn JA et al. Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs. Clin Endocrinol 2007;66:508-12.
    • (2007) Clin Endocrinol , vol.66 , pp. 508-512
    • Brand, O.J.1    Heward, J.M.2    Franklyn, J.A.3
  • 10
    • 43849113797 scopus 로고    scopus 로고
    • The crucial role of IL-2/IL-2RA-mediated immune regulation in the pathogenesis of type 1 diabetes, an evidence coming from genetic and animal model studies
    • Chistiakov DA, Voronova NV, Chistiakov PA. The crucial role of IL-2/IL-2RA-mediated immune regulation in the pathogenesis of type 1 diabetes, an evidence coming from genetic and animal model studies. Immunol Lett 2008;118:1-5.
    • (2008) Immunol Lett , vol.118 , pp. 1-5
    • Chistiakov, D.A.1    Voronova, N.V.2    Chistiakov, P.A.3
  • 11
    • 35448967862 scopus 로고    scopus 로고
    • Interleukin-2 receptor signaling in regulatory T cell development and homeostasis
    • Burchill MA, Yang J, Vang KB, Farrar MA. Interleukin-2 receptor signaling in regulatory T cell development and homeostasis. Immunol Lett 2007;114:1-8.
    • (2007) Immunol Lett , vol.114 , pp. 1-8
    • Burchill, M.A.1    Yang, J.2    Vang, K.B.3    Farrar, M.A.4
  • 12
    • 0028784289 scopus 로고
    • Interleukin-2 receptor a chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford DM, Chen J et al. Interleukin-2 receptor a chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995;3:521-30.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2
  • 13
    • 17544398702 scopus 로고    scopus 로고
    • Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
    • Refaeli Y, van Parijs L, London CA, Tschopp J, Abbas AK. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 1998;8:615-23.
    • (1998) Immunity , vol.8 , pp. 615-623
    • Refaeli, Y.1    van Parijs, L.2    London, C.A.3    Tschopp, J.4    Abbas, A.K.5
  • 14
    • 0348047537 scopus 로고    scopus 로고
    • The main function of IL-2 is to promote the development of T regulatory cells
    • Malek TR. The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol 2003;74:961-5.
    • (2003) J Leukoc Biol , vol.74 , pp. 961-965
    • Malek, T.R.1
  • 15
    • 33645852574 scopus 로고    scopus 로고
    • Regulation of Graves' hyperthyroidism with naturally occurring CD4+CD25+ regulatory T cells in a mouse model
    • Saitoh O, Nagayama Y. Regulation of Graves' hyperthyroidism with naturally occurring CD4+CD25+ regulatory T cells in a mouse model. Endocrinology 2006;147:2417-22.
    • (2006) Endocrinology , vol.147 , pp. 2417-2422
    • Saitoh, O.1    Nagayama, Y.2
  • 16
    • 34548526276 scopus 로고    scopus 로고
    • CD4+CD25+naturally occurring regulatory T cells and not lymphopenia play a role in the pathogenesis of iodide-induced autoimmune thyroiditis in NOD-H2h4 mice
    • Nagayama Y, Horie I, Saitoh O, Nakahara M, Abiru N. CD4+CD25+naturally occurring regulatory T cells and not lymphopenia play a role in the pathogenesis of iodide-induced autoimmune thyroiditis in NOD-H2h4 mice. J Autoimmun 2007;29:195-202.
    • (2007) J Autoimmun , vol.29 , pp. 195-202
    • Nagayama, Y.1    Horie, I.2    Saitoh, O.3    Nakahara, M.4    Abiru, N.5
  • 17
    • 36049042893 scopus 로고    scopus 로고
    • CD8+CD122+T cells, a newly identified regulatory T subset, negatively regulate Graves' hyperthyroidism in a murine model
    • Saitoh O, Abiru N, Nakahara M, Nagayama Y. CD8+CD122+T cells, a newly identified regulatory T subset, negatively regulate Graves' hyperthyroidism in a murine model. Endocrinology 2007;148:6040-6.
    • (2007) Endocrinology , vol.148 , pp. 6040-6046
    • Saitoh, O.1    Abiru, N.2    Nakahara, M.3    Nagayama, Y.4
  • 18
    • 1842734430 scopus 로고    scopus 로고
    • Influence of thyroxine on serum soluble interleukin-2 receptor alpha levels in thyroid disorders
    • Zwirska-Korczala K, Berdowska A, Jochem J et al. Influence of thyroxine on serum soluble interleukin-2 receptor alpha levels in thyroid disorders. J Clin Pharm Ther 2004;29:151-6.
    • (2004) J Clin Pharm Ther , vol.29 , pp. 151-156
    • Zwirska-Korczala, K.1    Berdowska, A.2    Jochem, J.3
  • 19
    • 64649104187 scopus 로고    scopus 로고
    • The relationship between thyroid function, serum monokine induced by interferon gamma and soluble interleukin-2 receptor in thyroid autoimmune diseases
    • Jiskra J, Antošová M, Límanová Z, Telička Z, Lacinová Z. The relationship between thyroid function, serum monokine induced by interferon gamma and soluble interleukin-2 receptor in thyroid autoimmune diseases. Exp Clin Immunol 2009;156:211-6.
    • (2009) Exp Clin Immunol , vol.156 , pp. 211-216
    • Jiskra, J.1    Antošová, M.2    Límanová, Z.3    Telička, Z.4    Lacinová, Z.5
  • 20
    • 0026740040 scopus 로고
    • Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein
    • Costagliola S, Swillens S, Noccoli P et al. Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein. J Clin Endocrinol Metab 1992;75:1540-4.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1540-1544
    • Costagliola, S.1    Swillens, S.2    Noccoli, P.3
  • 21
    • 0029031642 scopus 로고
    • Specific effects of radioiodine treatment on TSAb and TBAb levels in patients with Graves' disease
    • Michelangeli VP, Poon C, Topliss DJ, Colman PG. Specific effects of radioiodine treatment on TSAb and TBAb levels in patients with Graves' disease. Thyroid 1995;5:171-6.
    • (1995) Thyroid , vol.5 , pp. 171-176
    • Michelangeli, V.P.1    Poon, C.2    Topliss, D.J.3    Colman, P.G.4
  • 22
    • 0025850313 scopus 로고
    • Anti-thyroid peroxidase antibodies in thyroid disorders and non-thyroid autoimmune diseases
    • Feldt-Rasmussen U, Hoier-Madsen M, Bech K et al. Anti-thyroid peroxidase antibodies in thyroid disorders and non-thyroid autoimmune diseases. Autoimmunity 1991;9:245-54.
    • (1991) Autoimmunity , vol.9 , pp. 245-254
    • Feldt-Rasmussen, U.1    Hoier-Madsen, M.2    Bech, K.3
  • 23
    • 0034917719 scopus 로고    scopus 로고
    • High-throughput genotyping with single nucleotide polymorphisms
    • Ranade K, Chang MS, Ting CT et al. High-throughput genotyping with single nucleotide polymorphisms. Genome Res 2001;11:1262-8.
    • (2001) Genome Res , vol.11 , pp. 1262-1268
    • Ranade, K.1    Chang, M.S.2    Ting, C.T.3
  • 24
    • 85007745189 scopus 로고    scopus 로고
    • Statistics notes. The odds ratio
    • Bland JM, Altman DG. Statistics notes. The odds ratio. Br Med J 2000;320:1468.
    • (2000) Br Med J , vol.320 , pp. 1468
    • Bland, J.M.1    Altman, D.G.2
  • 26
    • 34047118563 scopus 로고    scopus 로고
    • Toward further mapping of the association between the IL2RA locus and type 1 diabetes
    • Qu HQ, Montpetit A, Ge B, Hudson TJ, Polychronakos C. Toward further mapping of the association between the IL2RA locus and type 1 diabetes. Diabetes 2007;56:1174-6.
    • (2007) Diabetes , vol.56 , pp. 1174-1176
    • Qu, H.Q.1    Montpetit, A.2    Ge, B.3    Hudson, T.J.4    Polychronakos, C.5
  • 27
    • 58949100205 scopus 로고    scopus 로고
    • IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production
    • Maier LM, Lowe CE, Cooper J et al. IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet 2009;5:e1000322.
    • (2009) PLoS Genet , vol.5
    • Maier, L.M.1    Lowe, C.E.2    Cooper, J.3
  • 28
    • 63449102458 scopus 로고    scopus 로고
    • Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis
    • Carr EJ, Clatworthy MR, Lowe CE et al. Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis. BMC Med Genet 2009;10:22.
    • (2009) BMC Med Genet , vol.10 , pp. 22
    • Carr, E.J.1    Clatworthy, M.R.2    Lowe, C.E.3
  • 29
    • 75649098698 scopus 로고    scopus 로고
    • The type I diabetes association of the IL2RA locus
    • Qu HQ, Bradfield JP, Bélisle A et al. The type I diabetes association of the IL2RA locus. Genes Immun 2009;10:S42-8.
    • (2009) Genes Immun , vol.10
    • Qu, H.Q.1    Bradfield, J.P.2    Bélisle, A.3
  • 30
    • 77953810227 scopus 로고    scopus 로고
    • Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk
    • Cavanillas ML, Alcina A, Núñez C, de las Heras V et al. Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk. Eur J Hum Genet 2010;18:794-9.
    • (2010) Eur J Hum Genet , vol.18 , pp. 794-799
    • Cavanillas, M.L.1    Alcina, A.2    Núñez, C.3    de las Heras, V.4
  • 31
    • 61449218868 scopus 로고    scopus 로고
    • Targeted screening of cis regulatory variation in human haplotypes
    • Verlaan DJ, Ge B, Grundberg E et al. Targeted screening of cis regulatory variation in human haplotypes. Genome Res 2009;19:118-27.
    • (2009) Genome Res , vol.19 , pp. 118-127
    • Verlaan, D.J.1    Ge, B.2    Grundberg, E.3
  • 33
    • 0024507322 scopus 로고
    • Interleukin-2 receptor levels indicating relapse in multiple sclerosis
    • Adachi K, Kumamoto T, Araki S. Interleukin-2 receptor levels indicating relapse in multiple sclerosis. Lancet 1989;1:559-60.
    • (1989) Lancet , vol.1 , pp. 559-560
    • Adachi, K.1    Kumamoto, T.2    Araki, S.3
  • 34
    • 0024427260 scopus 로고
    • Immune activation in multiple sclerosis: study of IL-2, sIL-2R, and gamma-IFN levels in serum and cerebrospinal fluid
    • Gallo P, Piccinno MG, Pagni S et al. Immune activation in multiple sclerosis: study of IL-2, sIL-2R, and gamma-IFN levels in serum and cerebrospinal fluid. J Neurol Sci 1989;92:9-15.
    • (1989) J Neurol Sci , vol.92 , pp. 9-15
    • Gallo, P.1    Piccinno, M.G.2    Pagni, S.3
  • 35
    • 63149109244 scopus 로고    scopus 로고
    • Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses
    • Maier LM, Anderson DE, Severson CA et al. Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses. J Immunol 2009;182:1541-7.
    • (2009) J Immunol , vol.182 , pp. 1541-1547
    • Maier, L.M.1    Anderson, D.E.2    Severson, C.A.3
  • 36
    • 0028981771 scopus 로고
    • Serum soluble interleukin-2 receptor, soluble CD8 and soluble intercellular adhesion molecule-1 levels in Crohn's disease, celiac disease, and systemic lupus erythematosus
    • Srivastava MD, Rossi TM, Lebenthal E. Serum soluble interleukin-2 receptor, soluble CD8 and soluble intercellular adhesion molecule-1 levels in Crohn's disease, celiac disease, and systemic lupus erythematosus. Res Commun Mol Pathol Pharmacol 1995;87:21-6.
    • (1995) Res Commun Mol Pathol Pharmacol , vol.87 , pp. 21-26
    • Srivastava, M.D.1    Rossi, T.M.2    Lebenthal, E.3
  • 37
    • 19944398438 scopus 로고    scopus 로고
    • Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus
    • Cheng SP, Liu JL, Yuan J. Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus. Chin J Integr Med 2005;11:65-8.
    • (2005) Chin J Integr Med , vol.11 , pp. 65-68
    • Cheng, S.P.1    Liu, J.L.2    Yuan, J.3
  • 38
    • 0033004134 scopus 로고    scopus 로고
    • Circulating P- and L-selectin and T-lymphocyte activation and patients with autoimmune rheumatic diseases
    • Sfikakis PP, Charalambopoulos D, Vaiopoulos G, Mavrikakis M. Circulating P- and L-selectin and T-lymphocyte activation and patients with autoimmune rheumatic diseases. Clin Rheumatol 1999;18:28-32.
    • (1999) Clin Rheumatol , vol.18 , pp. 28-32
    • Sfikakis, P.P.1    Charalambopoulos, D.2    Vaiopoulos, G.3    Mavrikakis, M.4
  • 39
    • 27544433561 scopus 로고    scopus 로고
    • Circulating soluble interleukin-2 receptor level predicts remission in very early reactive arthritis
    • Kuuliala A, Söderlin M, Kautiainen H, Repo H, Leirisalo-Repo M. Circulating soluble interleukin-2 receptor level predicts remission in very early reactive arthritis. Scand J Rheumatol 2005;34:372-5.
    • (2005) Scand J Rheumatol , vol.34 , pp. 372-375
    • Kuuliala, A.1    Söderlin, M.2    Kautiainen, H.3    Repo, H.4    Leirisalo-Repo, M.5
  • 40
    • 0035401110 scopus 로고    scopus 로고
    • Serum soluble IL-2 receptor as a marker of lymphocyte activation in some autoimmune diseases. Effect of immunosuppressive therapy
    • Dedijca D. Serum soluble IL-2 receptor as a marker of lymphocyte activation in some autoimmune diseases. Effect of immunosuppressive therapy. Roum Arch Microbiol Immunol 2001;60:183-201.
    • (2001) Roum Arch Microbiol Immunol , vol.60 , pp. 183-201
    • Dedijca, D.1
  • 41
    • 25644446532 scopus 로고    scopus 로고
    • Soluble interleukin-2 receptor in cancer
    • Murakami S. Soluble interleukin-2 receptor in cancer. Front Biosci 2004;9:3085-90.
    • (2004) Front Biosci , vol.9 , pp. 3085-3090
    • Murakami, S.1
  • 42
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 2004;199:971-9.
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 44
    • 79954988832 scopus 로고    scopus 로고
    • Impairment of regulatory capacity of CD4+CD25+regulatory T cells mediated by dendritic cell polarization and hyperthyroidism in Graves' disease
    • Mao C, Wang S, Xiao Y et al. Impairment of regulatory capacity of CD4+CD25+regulatory T cells mediated by dendritic cell polarization and hyperthyroidism in Graves' disease. J Immunol 2011;186:4734-43.
    • (2011) J Immunol , vol.186 , pp. 4734-4743
    • Mao, C.1    Wang, S.2    Xiao, Y.3
  • 46
    • 33846419491 scopus 로고    scopus 로고
    • Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals
    • Villarino AV, Tato CM, Stumhofer JS et al. Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals. J Exp Med 2007;204:65-71.
    • (2007) J Exp Med , vol.204 , pp. 65-71
    • Villarino, A.V.1    Tato, C.M.2    Stumhofer, J.S.3
  • 48
    • 0033631904 scopus 로고    scopus 로고
    • Serum cytokine levels in autoimmune and non-autoimmune hyperthyroid states
    • Ward LS, Fernandes GA. Serum cytokine levels in autoimmune and non-autoimmune hyperthyroid states. Braz J Med Biol Res 2000;33:65-9.
    • (2000) Braz J Med Biol Res , vol.33 , pp. 65-69
    • Ward, L.S.1    Fernandes, G.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.