The potential of mouse skin-derived precursors to differentiate into mesenchymal and neural lineages and their application to osteogenic induction in vivo

International Journal of Molecular Medicine

Volumn 28, Issue 6, 2011, Pages 1001-1011

  Kang, Hyun K ^a   Min, Seung Ki ^a   Jung, Sung Youn ^a   Jung, Kyoungsuk ^a   Jang, Da Hyun ^a   Kim, O Bok ^a   Chun, Gae Sig ^b   Lee, Zang Hee ^a   Min, Byung Moo ^a  

^a Seoul National University   (South Korea)

^b Institute of Tissue Regeneration Engineering   (South Korea)

Author keywords

Mesenchymal differentiation; Mouse skin; Neural differentiation; Osteogenic induction; Skin derived precursors

Indexed keywords

5' NUCLEOTIDASE; ACTIVATING TRANSCRIPTION FACTOR 3; ALPHA SMOOTH MUSCLE ACTIN; BETA1 INTEGRIN; BONE SIALOPROTEIN; CALDESMON; CCAAT ENHANCER BINDING PROTEIN ALPHA; CD133 ANTIGEN; CD51 ANTIGEN; COLLAGEN TYPE 2; HERMES ANTIGEN; OSTEOCALCIN; OSTEOPONTIN; PERIPHERIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SMOOTHELIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR SOX5; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE REMODELING; CELL DIFFERENTIATION; CELL LINEAGE; CHONDROGENESIS; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; MALE; MESENCHYMAL STEM CELL; MOUSE; NEURAL CREST STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SKIN; SKIN DERIVED PRECURSOR; STEM CELL; TISSUE ENGINEERING;

ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; CHONDROCYTES; FEMALE; MALE; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MULTIPOTENT STEM CELLS; MYOCYTES, SMOOTH MUSCLE; NEURAL CREST; NEURONS; OSTEOBLASTS; RATS; RATS, SPRAGUE-DAWLEY; SCHWANN CELLS; SKIN; SKULL; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING;

EID: 80053492917     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.785     Document Type: Article

References (33)

1. Joseph NM and Morrison SJ: Toward an understanding of the physiological function of Mammalian stem cells. Dev Cell 9: 173-183, 2005. (Pubitemid 41051737)
2. Toma JG, Akhavan M, Fernandes KJ, et al: Isolation of multi-potent adult stem cells from the dermis of mammalian skin. Nat Cell Biol 3: 778-784, 2001. (Pubitemid 32842682)
3. Jiang Y, Jahagirdar BN, Reinhardt RL, et al: Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418: 41-49, 2002. (Pubitemid 34742565)
4. Dicker A, Le Blanc K, Astrom G, et al: Functional studies of mesenchymal stem cells derived from adult human adipose tissue. Exp Cell Res 308: 283-290, 2005.
5. Joshi CV and Enver T: Plasticity revisited. Curr Opin Cell Biol 14: 749-755, 2002. (Pubitemid 35449389)
6. Lavoie JF, Biernaskie JA, Chen Y, et al: Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair. Stem Cells Dev 18: 893-906, 2009.
7. Fernandes KJ, McKenzie IA, Mill P, et al: A dermal niche for multipotent adult skin-derived precursor cells. Nat Cell Biol 6: 1082-1093, 2004. (Pubitemid 39468009)
8. Wong CE, Paratore C, Dours-Zimmermann MT, et al: Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol 175: 1005-1015, 2006. (Pubitemid 44969205)
9. McKenzie IA, Biernaskie J, Toma JG, Midha R and Miller FD: Skin-derived precursors generate myelinating Schwann cells for the injured and dysmyelinated nervous system. J Neurosci 26: 6651-6660, 2006. (Pubitemid 44318347)
10. Biernaskie JA, McKenzie IA, Toma JG and Miller FD: Isolation of skin-derived precursors (SKPs) and differentiation and enrichment of their Schwann cell progeny. Nat Protoc 1: 2803-2812, 2006.
11. Fernandes KJ, Kobayashi NR, Gallagher CJ, et al: Analysis of the neurogenic potential of multipotent skin-derived precursors. Exp Neurol 201: 32-48, 2006. (Pubitemid 44226463)
12. Toma JG, McKenzie IA, Bagli D and Miller FD: Isolation and characterization of multipotent skin-derived precursors from human skin. Stem Cells 23: 727-737, 2005. (Pubitemid 40791788)
13. Le Douarin NM, Creuzet S, Couly G and Dupin E: Neural crest cell plasticity and its limits. Development 131: 4637-4650, 2004. (Pubitemid 39433452)
14. Takashima Y, Era T, Nakao K, et al: Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell 129: 1377-1388, 2007. (Pubitemid 46970707)
15. Lee G, Kim H, Elkabetz Y, et al: Isolation and directed differ entiation of neural crest stem cells derived from human embryonic stem cells. Nat Biotechnol 25: 1468-1475, 2007. (Pubitemid 350233140)
16. Reynolds BA and Weiss S: Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255: 1707-1710, 1992.
17. Reynolds BA, Tetzlaff W and Weiss S: A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J Neurosci 12: 4565-4574, 1992.
18. Prockop DJ: Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276: 71-74, 1997.
19. Friedenstein AJ, Chailakhyan RK and Gerasimov UV: Bone marrow osteogenic stem cells: in vitro cultivation and transplantation in diffusion chambers. Cell Tissue Kinet 20: 263-272, 1987.
20. Haynesworth SE, Goshima J, Goldberg VM and Caplan AI: Characterization of cells with osteogenic potential from human marrow. Bone 13: 81-88, 1992.
21. zur Nieden NI, Price FD, Davis LA, Everitt RE and Rancourt DE: Gene profiling on mixed embryonic stem cell populations reveals a biphasic role for beta-catenin in osteogenic differentiation. Mol Endocrinol 21: 674-685, 2007.
22. Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF and Morrison SJ: Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425: 962-967, 2003. (Pubitemid 37376927)
23. Pittenger MF, Mackay AM, Beck SC, et al: Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147, 1999. (Pubitemid 29282067)
24. Kang HK, Roh S, Lee G, Hong SD, Kang H and Min BM: Osteogenic potential of embryonic stem cells in tooth sockets. Int J Mol Med 21: 539-544, 2008.
25. Schilling T, Noth U, Klein-Hitpass L, Jakob F and Schutze N: Plasticity in adipogenesis and osteogenesis of human mesenchymal stem cells. Mol Cell Endocrinol 271: 1-17, 2007. (Pubitemid 46803047)
26. Ramirez-Zacarias JL, Castro-Munozledo F and Kuri-Harcuch W: Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O. Histochemistry 97: 493-497, 1992.
27. Rodriguez LV, Alfonso Z, Zhang R, Leung J, Wu B and Ignarro LJ: Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells. Proc Natl Acad Sci USA 103: 12167-12172, 2006. (Pubitemid 44215829)
28. Bosnakovski D, Mizuno M, Kim G, et al: Chondrogenic differentiation of bovine bone marrow mesenchymal stem cells in pellet cultural system. Exp Hematol 32: 502-509, 2004. (Pubitemid 38624335)
29. Bursell L, Woods A, James CG, Pala D, Leask A and Beier F: Src kinase inhibition promotes the hondrocyte phenotype. Arthritis Res Ther 9: R105, 2007.
30. Biernaskie J, Sparling JS, Liu J, et al: Skin-derived precursors generate myelinating Schwann cells that promote remyelination and functional recovery after contusion spinal cord injury. J Neurosci 27: 9545-9559, 2007. (Pubitemid 47492191)
31. Weber M, Steinert A, Jork A, et al: Formation of cartilage matrix proteins by BMP-transfected murine mesenchymal stem cells encapsulated in a novel class of alginates. Biomaterials 23: 2003-2013, 2002. (Pubitemid 34251074)
32. Boo JS, Yamada Y, Okazaki Y, et al: Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold. J Craniofac Surg 13: 231-243, 2002.
33. Endres M, Hutmacher DW, Salgado AJ, et al: Osteogenic induction of human bone marrow-derived mesenchymal progenitor cells in novel synthetic polymer-hydrogel matrices. Tissue Eng 9: 689-702, 2003. (Pubitemid 37048111)