Atypical nervous system manifestations of HIV

Seminars in Neurology

Volumn 31, Issue 3, 2011, Pages 254-265

  Lyons, Jennifer ^a,b   Venna, Nagagopal ^a,b   Cho, Tracey A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

HIV; Human immunodeficiency virus; immune reconstitution inflammatory syndrome; myopathy; peripheral neuropathy

Indexed keywords

CORTICOSTEROID; IMMUNOMODULATING AGENT; INDINAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; ZIDOVUDINE;

ARTICLE; BRAIN INFECTION; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID ANALYSIS; CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY; DIFFUSE INFILTRATIVE LYMPHOCYTOSIS SYNDROME; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV ASSOCIATED NEUROMUSCULAR WEAKNESS SYNDROME; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; LYMPHOCYTOSIS; MENINGOENCEPHALOMYELITIS; MONONEUROPATHY; MONONEUROPATHY MULTIPLEX; MOTOR NEURON DISEASE; MYELITIS; NEUROMUSCULAR DISEASE; POLYMYOSITIS; PRIORITY JOURNAL; RISK FACTOR;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; HIV INFECTIONS; HIV-1; HUMANS; IMMUNE SYSTEM DISEASES; NERVOUS SYSTEM DISEASES;

EID: 80053483446     PISSN: 02718235     EISSN: 10989021     Source Type: Journal    
DOI: 10.1055/s-0031-1287653     Document Type: Article

References (137)

1. United Nations. UN AIDS Report on the Global AIDS Epidemic. Geneva United Nations 2010
2. McArthur J C., Brew B J., Nath A. Neurological complications of HIV infection. Lancet Neurol 2005 4 9 543-555 (Pubitemid 41139976)
3. Morgello S, Estanislao L, Simpson D et al, Manhattan HIV Brain Bank. HIV-associated distal sensory polyneuropathy in the era of highly active antiretroviral therapy: the Manhattan HIV Brain Bank. Arch Neurol 2004 61 4 546-551 (Pubitemid 38923745)
4. Power C, Boissé L, Rourke S, Gill M J. NeuroAIDS: an evolving epidemic. Can J Neurol Sci 2009 36 3 285-295
5. An S F., Groves M, Gray F, Scaravilli F. Early entry and widespread cellular involvement of HIV-1 DNA in brains of HIV-1 positive asymptomatic individuals. J Neuropathol Exp Neurol 1999 58 11 1156-1162 (Pubitemid 29519839)
6. Davis L E., Hjelle B L., Miller V E. et al. Early viral brain invasion in iatrogenic human immunodeficiency virus infection. Neurology 1992 42 9 1736-1739
7. Powderly W G. Current approaches to treatment for HIV-1 infection. J Neurovirol 2000 6 Suppl 1 S8-S13 (Pubitemid 30342772)
8. Crowe S, Zhu T, Muller W A. The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection. J Leukoc Biol 2003 74 5 635-641 (Pubitemid 38040338)
9. Gartner S. HIV infection and dementia. Science 2000 287 5453 602-604 (Pubitemid 30070897)
10. Maslin C L., Kedzierska K, Webster N L., Muller W A., Crowe S M. Transendothelial migration of monocytes: the underlying molecular mechanisms and consequences of HIV-1 infection. Curr HIV Res 2005 3 4 303-317 (Pubitemid 41655595)
11. McArthur J C., Steiner J, Sacktor N, Nath A. Human immunodeficiency virus-associated neurocognitive disorders: mind the gap. Ann Neurol 2010 67 6 699-714
12. Massari F E., Poli G, Schnittman S M., Psallidopoulos M C., Davey V, Fauci A S. In vivo T lymphocyte origin of macrophage-tropic strains of HIV. Role of monocytes during in vitro isolation and in vivo infection. J Immunol 1990 144 12 4628-4632 (Pubitemid 20224094)
13. Churchill M J., Gorry P R., Cowley D et al. Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues. J Neurovirol 2006 12 2 146-152 (Pubitemid 44574605)
14. Gorry P R., Ong C, Thorpe J et al. Astrocyte infection by HIV-1: mechanisms of restricted virus replication, and role in the pathogenesis of HIV-1-associated dementia. Curr HIV Res 2003 1 4 463-473
15. Li W, Li G, Steiner J, Nath A. Role of Tat protein in HIV neuropathogenesis. Neurotox Res 2009 16 3 205-220
16. Thompson K A., Churchill M J., Gorry P R. et al. Astrocyte specific viral strains in HIV dementia. Ann Neurol 2004 56 6 873-877 (Pubitemid 39578452)
17. Churchill M J., Wesselingh S L., Cowley D et al. Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia. Ann Neurol 2009 66 2 253-258
18. Dunfee R, Thomas E R., Gorry P R., Wang J, Ancuta P, Gabuzda D. Mechanisms of HIV-1 neurotropism. Curr HIV Res 2006 4 3 267-278 (Pubitemid 44027717)
19. Everall I P., Luthert P J., Lantos P L. Neuronal loss in the frontal cortex in HIV infection. Lancet 1991 337 8750 1119-1121
20. Wiley C A., Achim C. Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome. Ann Neurol 1994 36 4 673-676
21. González-Scarano F, Martín-García J. The neuropathogenesis of AIDS. Nat Rev Immunol 2005 5 1 69-81 (Pubitemid 40070332)
22. Ancuta P, Kamat A, Kunstman K J. et al. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS ONE 2008 3 6 e2516
23. McArthur J C., Haughey N, Gartner S et al. Human immunodeficiency virus-associated dementia: an evolving disease. J Neurovirol 2003 9 2 205-221 (Pubitemid 36656454)
24. Ho D D., Rota T R., Schooley R T. et al. Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. N Engl J Med 1985 313 24 1493-1497 (Pubitemid 16182477)
25. Keswani S C., Polley M, Pardo C A., Griffin J W., McArthur J C., Hoke A. Schwann cell chemokine receptors mediate HIV-1 gp120 toxicity to sensory neurons. Ann Neurol 2003 54 3 287-296 (Pubitemid 37072031)
26. Pardo C A., McArthur J C., Griffin J W. HIV neuropathy: insights in the pathology of HIV peripheral nerve disease. J Peripher Nerv Syst 2001 6 1 21-27 (Pubitemid 32240453)
27. Heckmann J M., Pillay K, Hearn A P., Kenyon C. Polymyositis in African HIV-infected subjects. Neuromuscul Disord 2010 20 11 735-739
28. Illa I, Nath A, Dalakas M. Immunocytochemical and virological characteristics of HIV-associated inflammatory myopathies: similarities with seronegative polymyositis. Ann Neurol 1991 29 5 474-481
29. Robinson-Papp J, Simpson D M. Neuromuscular diseases associated with HIV-1 infection. Muscle Nerve 2009 40 6 1043-1053
30. Sheikh S I., Nijhawan A, Basgoz N, Venna N. Reversible Cogan's syndrome in a patient with human immunodeficiency virus (HIV) infection. J Clin Neurosci 2009 16 1 154-156
31. Lange D J. AAEM minimonograph #41: neuromuscular diseases associated with HIV-1 infection. Muscle Nerve 1994 17 1 16-30
32. Serrano P, Hernández N, Arroyo J A., de Llobet J M., Domingo P. Bilateral Bell palsy and acute HIV type 1 infection: report of 2 cases and review. Clin Infect Dis 2007 44 6 e57-e61
33. Verma A, Berger J R. ALS syndrome in patients with HIV-1 infection. J Neurol Sci 2006 240 1-2 59-64 (Pubitemid 41814954)
34. Power C, Johnson R T. Emerging Neurological Infections. Boca Raton, FL Taylor and Francis Group 2005
35. Murdoch D M., Venter W D., Feldman C, Van Rie A. HIV immune reconstitution syndrome in sub-Saharan Africa. AIDS 2008 22 13 1689-1690
36. Shelburne S A., Visnegarwala F, Darcourt J et al. Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy. AIDS 2005 19 4 399-406 (Pubitemid 40446186)
37. Bélec L, Gherardi R, Georges A J. et al. Peripheral facial paralysis and HIV infection: report of four African cases and review of the literature. J Neurol 1989 236 7 411-414 (Pubitemid 19261894)
38. Komolafe M A., Fatusi O A., Alatise O I. et al. The role of human immunodeficiency virus infection in infranuclear facial paralysis. J Natl Med Assoc 2009 101 4 361-366
39. Chand V, Sweeney C, Agger W A. Mental neuropathy in patients with AIDS-associated malignant lymphoma. Clin Infect Dis 1997 24 3 521-522 (Pubitemid 27096821)
40. Brannagan T H. III, Zhou Y. HIV-associated Guillain-Barré syndrome. J Neurol Sci 2003 208 1-2 39-42
41. Souayah N, Mian N F., Gu Y, Ilyas A A. Elevated anti-sulfatide antibodies in Guillain-Barré syndrome in T cell depleted at end-stage AIDS. J Neuroimmunol 2007 188 1-2 143-145 (Pubitemid 47095023)
42. Cornblath D R., McArthur J C., Kennedy P G., Witte A S., Griffin J W. Inflammatory demyelinating peripheral neuropathies associated with human T-cell lymphotropic virus type III infection. Ann Neurol 1987 21 1 32-40 (Pubitemid 17004141)
43. Schleicher G K., Black A, Mochan A, Richards G A. Effect of human immunodeficiency virus on intensive care unit outcome of patients with Guillain-Barré syndrome. Crit Care Med 2003 31 6 1848-1850 (Pubitemid 36714246)
44. Vendrell J, Heredia C, Pujol M, Vidal J, Blesa R, Graus F. Guillain-Barré syndrome associated with seroconversion for anti-HTLV-III. Neurology 1987 37 3 544
45. Criteria for diagnosis of Guillain-Barré syndrome. Ann Neurol 1978 3 6 565-566
46. Bani-Sadr F, Neuville S, Crassard I, Guihot A, Molina J M. Acute Guillain-Barré syndrome during the chronic phase of HIV infection and dramatic improvement under highly active antiretroviral therapy. AIDS 2002 16 11 1562 (Pubitemid 34804225)
47. Thornton C A., Latif A S., Emmanuel J C. Guillain-Barré syndrome associated with human immunodeficiency virus infection in Zimbabwe. Neurology 1991 41 6 812-815
48. Chen-Plotkin A S., Christopoulos K A., Venna N. Demyelinating polyneuropathy and herpes simplex lumbosacral radiculitis in a patient with chronic HIV infection. AIDS 2007 21 12 1663-1664 (Pubitemid 47075497)
49. Benatar M G., Eastman R W. Human immunodeficiency virus-associated pure motor lumbosacral polyradiculopathy. Arch Neurol 2000 57 7 1034-1039 (Pubitemid 30452509)
50. Verma R K., Ziegler D K., Kepes J J. HIV-related neuromuscular syndrome simulating motor neuron disease. Neurology 1990 40 3 Pt 1 544-546 (Pubitemid 20117550)
51. Moulignier A, Moulonguet A, Pialoux G, Rozenbaum W. Reversible ALS-like disorder in HIV infection. Neurology 2001 57 6 995-1001 (Pubitemid 32880192)
52. Galassi G, Gentilini M, Ferrari S et al. Motor neuron disease and HIV-1 infection in a 30-year-old HIV-positive heroin abuser: a causal relationship? Clin Neuropathol 1998 17 3 131-135 (Pubitemid 28218489)
53. Hoffman P M., Festoff B W., Giron L T. Jr, Hollenbeck L C., Garruto R M., Ruscetti F W. Isolation of LAV/HTLV-III from a patient with amyotrophic lateral sclerosis. N Engl J Med 1985 313 5 324-325 (Pubitemid 15044238)
54. MacGowan D J., Scelsa S N., Waldron M. An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy. Neurology 2001 57 6 1094-1097 (Pubitemid 32880210)
55. Jubelt B. Motor neuron diseases and viruses: poliovirus, retroviruses, and lymphomas. Curr Opin Neurol Neurosurg 1992 5 5 655-658
56. MacGowan D J., Scelsa S N., Imperato T E., Liu K N., Baron P, Polsky B. A controlled study of reverse transcriptase in serum and CSF of HIV-negative patients with ALS. Neurology 2007 68 22 1944-1946 (Pubitemid 46848628)
57. Westarp M E., Ferrante P, Perron H, Bartmann P, Kornhuber H H. Sporadic ALS/MND: a global neurodegeneration with retroviral involvement? J Neurol Sci 1995 129 Suppl 145-147
58. Ferrante P, Westarp M E., Mancuso R et al. HTLV tax-rex DNA and antibodies in idiopathic amyotrophic lateral sclerosis. J Neurol Sci 1995 129 Suppl 140-144
59. Andrews W D., Al-Chalabi A, Garson J A. Lack of evidence for HTLV tax-rex DNA in motor neurone disease. J Neurol Sci 1997 153 1 86-90 (Pubitemid 28010072)
60. Cone L A., Nazemi R, Cone M O. Reversible ALS-like disorder in HIV infection. An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy. Neurology 2002 59 3 474 author reply 474-475
61. Sola P, Bedin R, Casoni F, Barozzi P, Mandrioli J, Merelli E. New insights into the viral theory of amyotrophic lateral sclerosis: study on the possible role of Kaposi's sarcoma-associated virus/human herpesvirus 8. Eur Neurol 2002 47 2 108-112 (Pubitemid 34161163)
62. Simpson D M., Morgello S, Citak K, Corbo M, Latov N. Motor neuron disease associated with HIV-1 and Anti-Asialo GM1 antibody. Muscle Nerve 1994 17 1091
63. Brooks B R. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial Clinical limits of amyotrophic lateral sclerosis workshop contributors. J Neurol Sci 1994 124 Suppl 96-107
64. Berger J R., Espinosa P S., Kissel J. Brachial amyotrophic diplegia in a patient with human immunodeficiency virus infection: widening the spectrum of motor neuron diseases occurring with the human immunodeficiency virus. Arch Neurol 2005 62 5 817-823 (Pubitemid 40656099)
65. Henning F, Hewlett R H. Brachial amyotrophic diplegia (segmental proximal spinal muscular atrophy) associated with HIV infection. J Neurol Neurosurg Psychiatry 2008 79 12 1392-1394
66. Verma A, Berger J R. Primary lateral sclerosis with HIV-1 infection. Neurology 2008 70 7 575-577 (Pubitemid 351653384)
67. Scelsa S N., MacGowan D J., Mitsumoto H et al. A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS. Neurology 2005 64 7 1298-1300
68. Simpson D M., Citak K A., Godfrey E, Godbold J, Wolfe D E. Myopathies associated with human immunodeficiency virus and zidovudine: can their effects be distinguished? Neurology 1993 43 5 971-976 (Pubitemid 23150571)
69. Dalakas M C., Rakocevic G, Shatunov A, Goldfarb L, Raju R, Salajegheh M. Inclusion body myositis with human immunodeficiency virus infection: four cases with clonal expansion of viral-specific T cells. Ann Neurol 2007 61 5 466-475 (Pubitemid 46878774)
70. Simpson D M., Bender A N. Human immunodeficiency virus-associated myopathy: analysis of 11 patients. Ann Neurol 1988 24 1 79-84
71. Johnson R W., Williams F M., Kazi S, Dimachkie M M., Reveille J D. Human immunodeficiency virus-associated polymyositis: a longitudinal study of outcome. Arthritis Rheum 2003 49 2 172-178 (Pubitemid 36418274)
72. Snider W D., Simpson D M., Nielsen S, Gold J W., Metroka C E., Posner J B. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol 1983 14 4 403-418 (Pubitemid 13010040)
73. Sellier P, Monsuez J J., Evans J et al. Human immunodeficiency virus-associated polymyositis during immune restoration with combination antiretroviral therapy. Am J Med 2000 109 6 510-512
74. Williams F M., Cohen P R., Jumshyd J, Reveille J D. Prevalence of the diffuse infiltrative lymphocytosis syndrome among human immunodeficiency virus type 1-positive outpatients. Arthritis Rheum 1998 41 5 863-868 (Pubitemid 28225787)
75. Basu D, Williams F M., Ahn C W., Reveille J D. Changing spectrum of the diffuse infiltrative lymphocytosis syndrome. Arthritis Rheum 2006 55 3 466-472 (Pubitemid 43887033)
76. Itescu S, Brancato L J., Buxbaum J et al. A diffuse infiltrative CD8 lymphocytosis syndrome in human immunodeficiency virus (HIV) infection: a host immune response associated with HLA-DR5. Ann Intern Med 1990 112 1 3-10 (Pubitemid 20026362)
77. Authier F J., Gheradi R K. Peripheral neuropathies in HIV-infected patients in the era of HAART. Brain Pathol 2003 13 2 223-228 (Pubitemid 36460822)
78. Gherardi R K., Chrétien F, Delfau-Larue M H. et al. Neuropathy in diffuse infiltrative lymphocytosis syndrome: an HIV neuropathy, not a lymphoma. Neurology 1998 50 4 1041-1044 (Pubitemid 28212835)
79. Moulignier A, Authier F J., Baudrimont M et al. Peripheral neuropathy in human immunodeficiency virus-infected patients with the diffuse infiltrative lymphocytosis syndrome. Ann Neurol 1997 41 4 438-445 (Pubitemid 27169182)
80. Kolson D L., Gonzalez-Scarano F. HIV-associated neuropathies: role of HIV-1, CMV, and other viruses. J Peripher Nerv Syst 2001 6 1 2-7 (Pubitemid 32240450)
81. Morgello S, Simpson D M. Multifocal cytomegalovirus demyelinative polyneuropathy associated with AIDS. Muscle Nerve 1994 17 2 176-182 (Pubitemid 24040223)
82. Simpson D M., Olney R K. Peripheral neuropathies associated with human immunodeficiency virus infection. Neurol Clin 1992 10 3 685-711
83. Wulff E A., Wang A K., Simpson D M. HIV-associated peripheral neuropathy: epidemiology, pathophysiology and treatment. Drugs 2000 59 6 1251-1260 (Pubitemid 30410143)
84. So Y T., Olney R K. The natural history of mononeuritis multiplex and simplex in HIV-infection. Neurology 1991 41 Suppl 1 375
85. HIV Neuromuscular Syndrome Study Group. HIV-associated neuromuscular weakness syndrome. AIDS 2004 18 10 1403-1412
86. French M A., Mallal S A., Dawkins R L. Zidovudine-induced restoration of cell-mediated immunity to mycobacteria in immunodeficient HIV-infected patients. AIDS 1992 6 11 1293-1297
87. Shelburne S A., Montes M, Hamill R J. Immune reconstitution inflammatory syndrome: more answers, more questions. J Antimicrob Chemother 2006 57 2 167-170 (Pubitemid 43160154)
88. Lortholary O, Fontanet A, Mémain N, Martin A, Sitbon K, Dromer F, French Cryptococcosis Study Group. Incidence and risk factors of immune reconstitution inflammatory syndrome complicating HIV-associated cryptococcosis in France. AIDS 2005 19 10 1043-1049 (Pubitemid 40961144)
89. Woods M L. II, MacGinley R, Eisen D P., Allworth A M. HIV combination therapy: partial immune restitution unmasking latent cryptococcal infection. AIDS 1998 12 12 1491-1494 (Pubitemid 28369649)
90. Murdoch D M., Venter W D., Feldman C, Van Rie A. Incidence and risk factors for the immune reconstitution inflammatory syndrome in HIV patients in South Africa: a prospective study. AIDS 2008 22 5 601-610 (Pubitemid 351640593)
91. Grant P M., Komarow L, Andersen J et al. Risk factor analyses for immune reconstitution inflammatory syndrome in a randomized study of early vs. deferred ART during an opportunistic infection. PLoS ONE 2010 5 7 e11416
92. Shelburne S A. III, Darcourt J, White A C. Jr et al. The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy. Clin Infect Dis 2005 40 7 1049-1052 (Pubitemid 40418316)
93. French M A., Price P, Stone S F. Immune restoration disease after antiretroviral therapy. AIDS 2004 18 12 1615-1627 (Pubitemid 39095778)
94. Johnson T, Nath A. Neurological complications of immune reconstitution in HIV-infected populations. Ann N Y Acad Sci 2010 1184 106-120
95. Marais S, Wilkinson R J., Pepper D J., Meintjes G. Management of patients with the immune reconstitution inflammatory syndrome. Curr HIV/AIDS Rep 2009 6 3 162-171
96. Zolopa A, Andersen J, Powderly W et al. Early antiretroviral therapy reduces AIDS progression/death in individuals with acute opportunistic infections: a multicenter randomized strategy trial. PLoS ONE 2009 4 5 e5575
97. McCombe J A., Auer R N., Maingat F G., Houston S, Gill M J., Power C. Neurologic immune reconstitution inflammatory syndrome in HIV/AIDS: outcome and epidemiology. Neurology 2009 72 9 835-841
98. Autran B, Carcelain G, Li T S. et al. Positive effects of combined antiretroviral therapy on CD4+T cell homeostasis and function in advanced HIV disease. Science 1997 277 5322 112-116 (Pubitemid 27450659)
99. Miller R F., Isaacson P G., Hall-Craggs M et al. Cerebral CD8+lymphocytosis in HIV-1 infected patients with immune restoration induced by HAART. Acta Neuropathol 2004 108 1 17-23 (Pubitemid 38961068)
100. Chávez-Galán L, Arenas-Del Angel M C., Zenteno E, Chávez R, Lascurain R. Cell death mechanisms induced by cytotoxic lymphocytes. Cell Mol Immunol 2009 6 1 15-25
101. Haddow L J., Colebunders R, Meintjes G et al, International Network for the Study of HIV-associated IRIS (INSHI). Cryptococcal immune reconstitution inflammatory syndrome in HIV-1-infected individuals: proposed clinical case definitions. Lancet Infect Dis 2010 10 11 791-802
102. Asselman V, Thienemann F, Pepper D J. et al. Central nervous system disorders after starting antiretroviral therapy in South Africa. AIDS 2010 24 18 2871-2876
103. Cattelan A M., Trevenzoli M, Sasset L, Lanzafame M, Marchioro U, Meneghetti F. Multiple cerebral cryptococcomas associated with immune reconstitution in HIV-1 infection. AIDS 2004 18 2 349-351 (Pubitemid 38253467)
104. Dautremer J, Pacanowski J, Girard P M., Lalande V, Sivignon F, Meynard J L. A new presentation of immune reconstitution inflammatory syndrome followed by a severe paradoxical reaction in an HIV-1-infected patient with tuberculous meningitis. AIDS 2007 21 3 381-382 (Pubitemid 46175055)
105. Meintjes G, Lawn S D., Scano F et al, International Network for the Study of HIV-associated IRIS. Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings. Lancet Infect Dis 2008 8 8 516-523 (Pubitemid 352005824)
106. Tan K, Roda R, Ostrow L, McArthur J, Nath A. PML-IRIS in patients with HIV infection: clinical manifestations and treatment with steroids. Neurology 2009 72 17 1458-1464
107. Lipman M, Breen R. Immune reconstitution inflammatory syndrome in HIV. Curr Opin Infect Dis 2006 19 1 20-25 (Pubitemid 43032435)
108. Venkataramana A, Pardo C A., McArthur J C. et al. Immune reconstitution inflammatory syndrome in the CNS of HIV-infected patients. Neurology 2006 67 3 383-388 (Pubitemid 44214957)
109. Berger J R. Steroids for PML-IRIS: a double-edged sword? Neurology 2009 72 17 1454-1455
110. Sax P E., Sloan C E., Schackman B R. et al, Cepac US And Actg A5164 Investigators. Early antiretroviral therapy for patients with acute aids-related opportunistic infections: a cost-effectiveness analysis of ACTG A5164. HIV Clin Trials 2010 11 5 248-259
111. Canestri A, Lescure F X., Jaureguiberry S et al. Discordance between cerebral spinal fluid and plasma HIV replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy. Clin Infect Dis 2010 50 5 773-778
112. Letendre S, Marquie-Beck J, Capparelli E et al, CHARTER Group. Validation of the CNS penetration-effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol 2008 65 1 65-70
113. Letendre S L., Ellis R J., Ances B M., McCutchan J A. Neurologic complications of HIV disease and their treatment. Top HIV Med 2010 18 2 45-55
114. Boissé L, Gill M J., Power C. HIV infection of the central nervous system: clinical features and neuropathogenesis. Neurol Clin 2008 26 3 799-819 (Pubitemid 352037443)
115. Connor M D., Lammie G A., Bell J E., Warlow C P., Simmonds P, Brettle R D. Cerebral infarction in adult AIDS patients: observations from the Edinburgh HIV Autopsy Cohort. Stroke 2000 31 9 2117-2126
116. Brilla R, Nabavi D G., Schulte-Altedorneburg G et al. Cerebral vasculopathy in HIV infection revealed by transcranial Doppler: A pilot study. Stroke 1999 30 4 811-813 (Pubitemid 29156373)
117. Dal Pan G J., Glass J D., McArthur J C. Clinicopathologic correlations of HIV-1-associated vacuolar myelopathy: an autopsy-based case-control study. Neurology 1994 44 11 2159-2164 (Pubitemid 24349523)
118. Grant I, Martin A. Neuropathology of HIV Infection. Vol. 494. New York Oxford University Press 1994
119. Lang W, Miklossy J, Deruaz J P. et al. Neuropathology of the acquired immune deficiency syndrome (AIDS): a report of 135 consecutive autopsy cases from Switzerland. Acta Neuropathol 1989 77 4 379-390 (Pubitemid 19070180)
120. Rosenblum M L., Levy R M., Bredesen D E., So Y T., Wara W, Ziegler J L. Primary central nervous system lymphomas in patients with AIDS. Ann Neurol 1988 23 Suppl S13-S16
121. Welch K, Finkbeiner W, Alpers C E. et al. Autopsy findings in the acquired immune deficiency syndrome. JAMA 1984 252 9 1152-1159 (Pubitemid 14067514)
122. Anderson A M., Fountain J A., Green S B., Bloom S A., Palmore M P. Human immunodeficiency virus-associated cytomegalovirus infection with multiple small vessel cerebral infarcts in the setting of early immune reconstitution. J Neurovirol 2010 16 2 179-184
123. Berkeley J L., Nath A, Pardo C A. Fatal immune reconstitution inflammatory syndrome with human immunodeficiency virus infection and Candida meningitis: case report and review of the literature. J Neurovirol 2008 14 3 267-276 (Pubitemid 351895548)
124. Broom J, Woods M II, Allworth A. Immune reconstitution inflammatory syndrome producing atypical presentations of cryptococcal meningitis: case report and a review of immune reconstitution-associated cryptococcal infections. Scand J Infect Dis 2006 38 3 219-221
125. French M A., Lenzo N, John M et al. Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy. HIV Med 2000 1 2 107-115
126. Lawn S D. Immune reconstitution disease associated with parasitic infections following initiation of antiretroviral therapy. Curr Opin Infect Dis 2007 20 5 482-488 (Pubitemid 47359644)
127. Lee C H., Lui C C., Liu J W. Immune reconstitution syndrome in a patient with AIDS with paradoxically deteriorating brain tuberculoma. AIDS Patient Care STDS 2007 21 4 234-239
128. Lindzen E, Jewells V, Bouldin T, Speer D, Royal W III, Markovic-Plese S. Progressive tumefactive inflammatory central nervous system demyelinating disease in an acquired immunodeficiency syndrome patient treated with highly active antiretroviral therapy. J Neurovirol 2008 14 6 569-573
129. Melica G, Brugieres P, Lascaux A S., Levy Y, Lelivre J D. Primary vasculitis of the central nervous system in patients infected with HIV-1 in the HAART era. J Med Virol 2009 81 4 578-581
130. Newsome S D., Nath A. Varicella-zoster virus vasculopathy and central nervous system immune reconstitution inflammatory syndrome with human immunodeficiency virus infection treated with steroids. J Neurovirol 2009 15 3 288-291
131. Nolan R C., Chidlow G, French M A. Parvovirus B19 encephalitis presenting as immune restoration disease after highly active antiretroviral therapy for human immunodeficiency virus infection. Clin Infect Dis 2003 36 9 1191-1194 (Pubitemid 36549643)
132. Patel A K., Patel K K., Shah S D., Desai J. Immune reconstitution syndrome presenting with cerebral varicella zoster vasculitis in HIV-1-infected patient: a case report. J Int Assoc Physicians AIDS Care (Chic) 2006 5 4 157-160
133. Pfeffer G, Prout A, Hooge J, Maguire J. Biopsy-proven immune reconstitution syndrome in a patient with AIDS and cerebral toxoplasmosis. Neurology 2009 73 4 321-322
134. Teo E C., Azwra A, Jones R L., Gazzard B G., Nelson M. Guillain-Barre syndrome following immune reconstitution after antiretroviral therapy for primary HIV infection. J HIV Ther 2007 12 3 62-63 (Pubitemid 350086016)
135. Toro C, Blanco F, García-Gascó P et al. Human T lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis in an HIV-positive patient coinfected with human T lymphotropic virus type 2 following initiation of antiretroviral therapy. Clin Infect Dis 2007 45 9 e118-e120 (Pubitemid 47580339)
136. Vidal J E., Fink M C., Cedeno-Laurent F et al. BK virus associated meningoencephalitis in an AIDS patient treated with HAART. AIDS Res Ther 2007 4 13
137. York J, Bodi I, Reeves I, Riordan-Eva P, Easterbrook P J. Raised intracranial pressure complicating cryptococcal meningitis: immune reconstitution inflammatory syndrome or recurrent cryptococcal disease? J Infect 2005 51 2 165-171 (Pubitemid 40984353)