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Volumn 18, Issue 7, 2011, Pages 598-607

A Human Neutralizing Antibody Specific to Ang-2 Inhibits Ocular Angiogenesis

Author keywords

Angiogenesis; Angiopoietin 2; Ocular neovascularization

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; NEUTRALIZING ANTIBODY; OXYGEN; VASCULOTROPIN ANTIBODY;

EID: 80053463397     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1111/j.1549-8719.2011.00120.x     Document Type: Article
Times cited : (33)

References (26)
  • 3
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8: 592-603, 2008.
    • (2008) Nat Rev Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 5
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186, 1971.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 10
    • 77954890371 scopus 로고    scopus 로고
    • Targeting the ANGPT-TIE2 pathway in malignancy
    • Huang H, Bhat A, Woodnutt G, Lappe R. Targeting the ANGPT-TIE2 pathway in malignancy. Nat Rev Cancer 10: 575-585, 2010.
    • (2010) Nat Rev Cancer , vol.10 , pp. 575-585
    • Huang, H.1    Bhat, A.2    Woodnutt, G.3    Lappe, R.4
  • 12
    • 33644863498 scopus 로고    scopus 로고
    • Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF
    • Liang WC, Wu X, Peale FV, Lee CV, Meng YG, Gutierrez J, Fu L, Malik AK, Gerber HP, Ferrara N, Fuh G. Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF. J Biol Chem 281: 951-961, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 951-961
    • Liang, W.C.1    Wu, X.2    Peale, F.V.3    Lee, C.V.4    Meng, Y.G.5    Gutierrez, J.6    Fu, L.7    Malik, A.K.8    Gerber, H.P.9    Ferrara, N.10    Fuh, G.11
  • 13
    • 0037143737 scopus 로고    scopus 로고
    • Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
    • Lobov IB, Brooks PC, Lang RA. Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci USA 99: 11205-11210, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11205-11210
    • Lobov, I.B.1    Brooks, P.C.2    Lang, R.A.3
  • 18
    • 0032985888 scopus 로고    scopus 로고
    • Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells
    • Oh H, Takagi H, Suzuma K, Otani A, Matsumura M, Honda Y. Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells. J Biol Chem 274: 15732-15739, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 15732-15739
    • Oh, H.1    Takagi, H.2    Suzuma, K.3    Otani, A.4    Matsumura, M.5    Honda, Y.6
  • 23
    • 3843137304 scopus 로고    scopus 로고
    • Ocular wounding prevents pre-retinal neovascularization and upregulates PEDF expression in the inner retina
    • Stitt AW, Graham D, Gardiner TA. Ocular wounding prevents pre-retinal neovascularization and upregulates PEDF expression in the inner retina. Mol Vis 10: 432-438, 2004.
    • (2004) Mol Vis , vol.10 , pp. 432-438
    • Stitt, A.W.1    Graham, D.2    Gardiner, T.A.3
  • 26
    • 70350704800 scopus 로고    scopus 로고
    • Current molecular understanding and future treatment strategies for pathologic ocular neovascularization
    • Tolentino MJ. Current molecular understanding and future treatment strategies for pathologic ocular neovascularization. Curr Mol Med 9: 973-981, 2009.
    • (2009) Curr Mol Med , vol.9 , pp. 973-981
    • Tolentino, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.