Reduction in ventilator associated pneumonia in a mixed intensive care unit after initiation of a novel hand hygiene program

Journal of Critical Care

Volumn 26, Issue 5, 2011, Pages 489-495

  Koff, Matthew D ^a   Corwin, Howard L ^a   Beach, Michael L ^a   Surgenor, Steven D ^a   Loftus, Randy W ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Catheter related bloodstream infection; Hand hygiene; Healthcare associated infections; Multimodal; Ventilator associated pneumonia

Indexed keywords

ADULT; ARTICLE; BLOODSTREAM INFECTION; CATHETER INFECTION; CONTROLLED STUDY; EDUCATION; FEEDBACK SYSTEM; FEMALE; HAND HYGIENE; HOSPITAL HYGIENE; HUMAN; INCIDENCE; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PATIENT ASSESSMENT; PATIENT CARE; PATIENT COMPLIANCE; PROTECTIVE EQUIPMENT; RISK REDUCTION; VENTILATOR ASSOCIATED PNEUMONIA;

ADULT; AGED; FEMALE; GUIDELINE ADHERENCE; HANDWASHING; HUMANS; HYGIENE; INFECTION CONTROL; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; PROGRAM EVALUATION;

EID: 80053459476     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2010.12.013     Document Type: Article

References (59)

1. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 2004, 32:470-485.
2. Guideline for prevention of nosocomial pneumonia. Centers for Disease Control and Prevention. Respir Care 1994, 39:1191-1236.
3. Klevens R.M., Morrison M.A., Nadle J., et al. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 2007, 298:1763-1771.
4. Medicare Program; Proposed Changes to the Hospital Inpatient Prospective Payment Systems and Fiscal Year 2008 Rates; Proposed Rule Part II, in Department of Health Human SCf, Medicare & Medicaid, Services (ed): Federal Register (ed 85), 2008, pp 38-48.
5. Craven D.E. Preventing Ventilator-Associated Pneumonia in Adults. Chest 2006, 130:251-260.
6. Craven D.E., Palladino R., McQuillen D.P. Healthcare-associated pneumonia in adults: management principles to improve outcomes. Infect Dis Clin North Am 2004, 18:939-962.
7. Dellinger E.P., Gordon S. Surgical-Associated Infection in Today's Operating Room: Anesthesiology, General Surgery, and OB-GYN News, McMahon Publishing Group 2006, 1-10.
8. Hayden M.K. Insights into the epidemiology and control of infection with vancomycinresistant enterococci. Clin Infect Dis 2000, 31:1058-1065.
9. Saye DE. Recurring and antimicrobial-resistant infections:considering the potential role of biofilms in clinical practice. Ostomy Wound Manage 2007;53:46-48, 50.
10. Sheretz R. Catheter Related Infections: Pathogenesis of vascular catheter-related infections 1997, 1-30. Mercel Dekker, New York. 1st ed.
11. Bischoff W.E., Reynolds T.M., Sessler C.N., et al. Handwashing compliance by health care workers: The impact of introducing an accessible, alcohol-based hand antiseptic. Arch Intern Med 2000, 160:1017-1021.
12. Conly J.M., Hill S., Ross J., et al. Handwashing practices in an intensive care unit: the effects of an educational program and its relationship to infection rates. Am J Infect Control 1989, 17:330-339.
13. Dubbert P.M., Dolce J., Richter W., et al. Increasing ICU staff handwashing: effects of education and group feedback. Infect Control Hosp Epidemiol 1990, 11:191-193.
14. Gould D., Chamberlain A. The use of a ward-based educational teaching package to enhance nurses' compliance with infection control procedures. J Clin Nurs 1997, 6:55-67.
15. Gould D.J., Chudleigh J.H., Moralejo D., et al. Interventions to improve hand hygiene compliance in patient care. Cochrane Database Syst Rev 2007, CD005186.
16. Huang J., Jiang D., Wang X., et al. Changing knowledge, behavior, and practice related to universal precautions among hospital nurses in China. J Contin Educ Nurs 2002, 33:217-224.
17. Hugonnet S., Perneger T.V., Pittet D. Alcohol-based handrub improves compliance with hand hygiene in intensive care units. Arch Intern Med 2002, 162:1037-1043.
18. Kaplan L.M., McGuckin M. Increasing handwashing compliance with more accessible sinks. Infect Control 1986, 7:408-410.
19. Kretzer E.K., Larson E.L. Behavioral interventions to improve infection control practices. Am J Infect Control 1998, 26:245-253.
20. Larson E.L. APIC guideline for handwashing and hand antisepsis in health care settings. Am J Infect Control 1995, 23:251-269.
21. Larson E.L., Bryan J.L., Adler L.M., et al. A multifaceted approach to changing handwashing behavior. Am J Infect Control 1997, 25:3-10.
22. Larson E.L., Early E., Cloonan P., et al. An organizational climate intervention associated with increased handwashing and decreased nosocomial infections. Behav Med 2000, 26:14-22.
23. Mayer J.A., Dubbert P.M., Miller M., et al. Increasing handwashing in an intensive care unit. Infect Control 1986, 7:259-262.
24. McGuckin M., Waterman R., Porten L., et al. Patient education model for increasing handwashing compliance. Am J Infect Control 1999, 27:309-314.
25. Moongtui W., Gauthier D.K., Turner J.G. Using peer feedback to improve handwashing and glove usage among Thai health care workers. Am J Infect Control 2000, 28:365-369.
26. Panhotra B., Saxena A., Al-Arabi A.G.A. The effect of a continuous educational program on handwashing compliance among healthcare workers in an intensive care unit. Br J Infect Control 2004, 5:15-18.
27. Pittet D., Hugonnet S., Harbarth S., et al. Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme. Lancet 2000, 356:1307-1312.
28. Pittet D., Mourouga P., Perneger T.V., et al. Compliance with Handwashing in a Teaching Hospital. Ann Intern Med 1999, 130:126-130.
29. Salemi C., Canola M.T., Eck E.K. Hand washing and physicians: how to get them together. Infect Control Hosp Epidemiol 2002, 23:32-35.
30. van de Mortel T., Bourke R., Fillipi L., et al. Maximising handwashing rates in the critical care unit through yearly performance feedback. Aust Crit Care 2000, 13:91-95.
31. Rosenthal V.D., Guzman S., Safdar N. Reduction in nosocomial infection with improved hand hygiene in intensive care units of a tertiary care hospital in Argentina. Am J Infect Control 2005, 33:392-397.
32. Rupp M., Fitzgerald T., Puumala S., et al. Prospective, Controlled, Cross Over Trial of Alcohol Based Hand Gel in Critical Care Units. Infect Control Hosp Epidemiol 2008, 29:8-15.
33. WHO Guidelines on Hand Hygiene in Health Care. First Global Patient Safety Challenge Clean Care is Safer Care http://whqlibdoc.who.int/publications/2009/9789241597906_eng.pdf.
34. Boyce JM, Pittet D: Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. MMWR Recomm Rep 51:1-45.
35. Gould D.J., Drey N.S., Moralejo D., et al. Interventions to improve hand hygiene compliance in patient care. J Hosp Infect 2008, 68:193-202.
36. Bouadma L., Mourvillier B., Deiler V., et al. A multifaceted program to prevent ventilator associated pneumonia: Impact on compliance with preventive measures. Crit Care Med 2010, 38:789-796.
37. Costello J.M., Morrow D.F., Graham D.A., et al. Systematic intervention to reduce central line-associated bloodstream infection rates in a pediatric cardiac intensive care unit. Pediatrics 2008, 121:915-923.
38. Cocanour C.S., Peninger M., Domonoske B.D., et al. Decreasing ventilator-associated pneumonia in a trauma ICU. J Trauma 2006, 61:122-129. discussion 129-30.
39. Kollef M.H., Fraser V.J. Antibiotic Resistance in the Intensive Care Unit. Ann Intern Med 2001, 134:298-314.
40. Laupland K.B., Lee H., Gregson D.B., et al. Cost of intensive care unit-acquired bloodstream infections. J Hosp Infect 2006, 63:124-132.
41. Orsi G.B., Di S.L., Noah N. Hospital-acquired, laboratory-confirmed bloodstream infection: increased hospital stay and direct costs. Infect Control Hosp Epidemiol 2002, 23:190-197.
42. Rello J., Lorente C., Bodi M., et al. Why do physicians not follow evidence-based guidelines for preventing ventilator-associated pneumonia?: a survey based on the opinions of an international panel of intensivists. Chest 2002, 122:656-661.
43. Safdar N., Dezfulian C., Collard H.R., et al. Clinical and economic consequences of ventilator-associated pneumonia: a systematic review. Crit Care Med 2005, 33:2184-2193.
44. Stone P.W., Larson E., Kawar L.N. A systematic audit of economic evidence linking nosocomial infections and infection control interventions: 1990-2000. Am J Infect Control 2002, 30:145-152.
45. Vincent J.L. Nosocomial infections in adult intensive-care units. Lancet 2003, 361:2068-2077.
46. Warren D.K., Shukla S.J., Olsen M.A., et al. Outcome and attributable cost of ventilatorassociated pneumonia among intensive care unit patients in a suburban medical center. Crit Care Med 2003, 31:1312-1317.
47. Koff M.D., Loftus R.W., Burchman C.C., et al. Reduction in intraoperative bacterial contamination of peripheral intravenous tubing through the use of a novel device. Anesthesiology 2009, 110:978-985.
48. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005, 171:388-416.
49. Anderson D.J., Richet H., Chen L.F., et al. Seasonal variation in Klebsiella pneumoniae bloodstream infection on 4 continents. J Infect Dis 2008, 197:752-756.
50. McDonald L.C., Banerjee S.N., Jarvis W.R. Seasonal variation of Acinetobacter infections: 1987-1996. Nosocomial Infections Surveillance System. Clin Infect Dis 1999, 29:1133-1137.
51. Vincent J.L., Rello J., Marshall J., et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA 2009, 302:2323-2329.
52. Institute for Healthcare Improvement, 2010.
53. Resar R., Pronovost P., Haraden C., et al. Using a bundle approach to improve ventilator care processes and reduce ventilator-associated pneumonia. Jt Comm J Qual Patient Saf 2005, 31:243-248.
54. Wip C., Napolitano L. Bundles to prevent ventilator-associated pneumonia: how valuable are they?. Curr Opin Infect Dis 2009, 22:159-166.
55. Kollef M.H. The Prevention of Ventilator-Associated Pneumonia. N Engl J Med 1999, 340:627-634.
56. Tolentino-DelosReyes A.F., Ruppert S.D., Shiao S.Y. Evidence-based practice: use of the ventilator bundle to prevent ventilator-associated pneumonia. Am J Crit Care 2007, 16:20-27.
57. Trampuz A., Widmer A.F. Hand hygiene: a frequently missed lifesaving opportunity during patient care. Mayo Clin Proc 2004, 79:109-116.
58. Zingg W., Imhof A., Maggiorini M., et al. Impact of a prevention strategy targeting hand hygiene and catheter care on the incidence of catheter-related bloodstream infections. Crit Care Med 2009, 37:2167-2173. quiz 2180.
59. Pronovost P., Needham D., Berenholtz S., et al. An intervention to decrease catheterrelated bloodstream infections in the ICU. N Engl J Med 2006, 355:2725-2732.