The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 11, 2011, Pages 1522-1531

  Renga, Barbara ^a   Mencarelli, Andrea ^a   Cipriani, Sabrina ^a   D'Amore, Claudio ^a   Zampella, Angela ^b   Monti, Maria Chiara ^c   Distrutti, Eleonora ^d   Fiorucci, Stefano ^a,d  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF SALERNO   (Italy)

^d SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

Author keywords

FXR; Glutamate; Glutamine; Hyperammonemia; NAGS; Urea cycle

Indexed keywords

FARNESOID X RECEPTOR; GLUTAMATE ACETYLTRANSFERASE; GLUTAMIC ACID; GLUTAMINE;

AMINO ACID METABOLISM; AMINO ACID SEQUENCE; AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRAIN HEPG2; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER CELL CULTURE; LIVER FAILURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; RECEPTOR UPREGULATION; WILD TYPE;

AMINO-ACID N-ACETYLTRANSFERASE; ANIMALS; BLOTTING, WESTERN; CARBON TETRACHLORIDE; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GLUTAMATES; GLUTAMINE; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYPERAMMONEMIA; LIVER CIRRHOSIS, EXPERIMENTAL; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MUS; RODENTIA;

EID: 80053446828     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2011.06.009     Document Type: Article

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