Baculoviruses deficient in ie1 gene function abrogate viral gene expression in transduced mammalian cells

Virology

Volumn 406, Issue 2, 2010, Pages 293-301

  Efrose, Rodica ^a   Swevers, Luc ^a   Iatrou, Kostas ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

AcMNPV; Defective baculovirus particles; Gene delivery vehicles; Gene therapy vectors; Ie1 knockout mutant; Immediate early 1 gene; Viral gene transduction

Indexed keywords

IMMEDIATE EARLY PROTEIN 1; UNCLASSIFIED DRUG; VIRUS PROTEIN; AC-IE-1 PROTEIN, AUTOGRAPHA CALIFORNICA NUCLEOPOLYHEDROVIRUS; IMMEDIATE EARLY PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; BACULOVIRUS; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE VECTOR; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; INSECT CELL; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERTANT; VIRUS CELL INTERACTION; VIRUS REPLICATION; ANIMAL; BACULOVIRIDAE; CELL LINE; DEFICIENCY; DEVICES; GENE THERAPY; GENETICS; METABOLISM; SPODOPTERA;

ANIMALS; CELL LINE; GENE EXPRESSION REGULATION, VIRAL; GENE THERAPY; HUMANS; IMMEDIATE-EARLY PROTEINS; NUCLEOPOLYHEDROVIRUS; SPODOPTERA; TRANS-ACTIVATORS; TRANSDUCTION, GENETIC; GENETIC THERAPY;

AUTOGRAPHA CALIFORNICA NUCLEOPOLYHEDROVIRUS; HEXAPODA; MAMMALIA;

EID: 80053439126     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2010.07.020     Document Type: Article

References (49)

1. Abe T., Takahashi H., Hamazaki H., Miyano-Kurosaki N., Matsuura Y., Takaku H. Baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice. J. Immunol. 2003, 171:1133-1139.
2. Boulaire J., Zhao Y., Wang S. Gene expression profiling to define host response to baculoviral transduction in the brain. J. Neurochem. 2009, 109:1203-1214.
3. Boyce F.M., Bucher N. Baculovirus mediated gene transfer into mammalian cells. Proc. Natl Acad. Sci. USA 1996, 93:2348-2352.
4. Cavener D.R. Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res. 1987, 15:1353-1361.
5. Cheshenko N., Krougliak N., Eisensmith R.C., Krougliak V.A. A novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus. Gene Ther. 2001, 8:846-854.
6. Choi J., Guarino L.A. A temperature-sensitive IE1 protein of Autographa californica nuclear polyhedrosis virus has altered transactivation and DNA binding activities. Virology 1995, 209:90-98.
7. Chuang C.-K., Wong T.-H., Hwang S.-M., Chang Y.-H., Chen G.-Y., Chiu Y.-C., Huang S.-F., Hu Y.-C. Baculovirus transduction of mesenchymal stem cells: in vitro responses and in vivo immune responses after cell transplantation. Mol. Ther. 2009, 17:889-896.
8. Dai X., Willis L.G., Huijskens I., Palli S.R., Theilmann D.A. The acidic activation domains of the baculovirus transactivators IE1 and IE0 are functional for transcriptional activation in both insect and mammalian cells. J. Gen. Virol. 2004, 85:573-582.
9. Dong S., Wang M., Qiu Z., Deng F., Vlak J.M., Hu Z., Wang H. Autographa californica multicapsid nucleopolyhedrovirus efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH. J. Virol. 2010, 84:5351-5359.
10. Douris V., Swevers L., Labropoulou V., Andronopoulou E., Georgoussi Z., Iatrou K. Stably transformed insect cell lines: tools for expression of secreted and membrane-anchored proteins and high-throughput screening platforms for drug and insecticide discovery. Adv. Virus Res. 2006, 68:113-156.
11. Facciabene A., Aurisicchio L., La Monica N. Baculovirus vectors elicit antigen-specific immune responses in mice. J. Virol. 2004, 78:8663-8672.
12. Farrell P.J., Behie L.A., Iatrou K. Secretion of cytoplasmic and nuclear proteins from animal cells using novel secretion modules. Proteins 2000, 41:144-153.
13. Fujita R., Matsuyama T., Yamagishi J., Sahara K., Asano S., Bando H. Expression of Autographa californica multiple nucleopolyhedrovirus genes in mammalian cells and upregulation of the host beta-actin gene. J. Virol. 2006, 80:2390-2395.
14. Gao R., McCormick C.J., Arthur M.J., Ruddell R., Oakley F., Smart D.E., Murphy F.R., Harris M.P., Mann D.A. High efficiency gene transfer into cultured primary rat and human hepatic stellate cells using baculovirus vectors. Liver 2002, 22:15-22.
15. Georgopoulos L.J., Elgue G., Sanchez J., Dussupt V., Magotti P., Lambris J.D., Tötterman T.H., Maitland N.J., Nilsson B. Preclinical evaluation of innate immunity to baculovirus gene therapy vectors in whole human blood. Mol. Immunol. 2009, 46:2911-2917.
16. Gronowski A.M., Hilbert D.M., Sheehan K.C., Garotta G., Schreiber R.D. Baculovirus stimulates antiviral effects in mammalian cells. J. Virol. 1999, 73:9944-9951.
17. Guarino L.A., Summers M.D. Nucleotide sequence and temporal expression of a baculovirus regulatory gene. J. Virol. 1987, 61:2091-2099.
18. Hofmann C., Sandig V., Jennings G., Rudolph M., Schlag P., Strauss M. Efficient gene-transfer into human hepatocytes by baculovirus vectors. Proc. Natl Acad. Sci. USA 1995, 92:10099-10103.
19. Hu Y.C. Baculovirus vectors for gene therapy. Adv. Virus Res. 2006, 68:287-320.
20. Huijskens I., Li L., Willis L.G., Theilmann D.A. Role of AcMNPV IE0 in baculovirus very late gene activation. Virology 2004, 323:120-130.
21. Iatrou K., Swevers L. Transformed lepidopteran cells expressing a protein of the silkmoth fat body display enhanced susceptibility to baculovirus infection and produce high titers of budded virus in serum-free media. J. Biotechnol. 2005, 120:237-250.
22. Johnson R., Meidinger R.G., Iatrou K. A cellular promoter-based expression cassette for generating recombinant baculoviruses directing rapid expression of passenger genes in infected insects. Virology 1992, 190:815-823.
23. Kaname Y., Tani H., Kataoka C., Shiokawa M., Taquwa S., Abe T., Moriishi K., Konishita T., Matsuura Y. Acquisition of complement resistance through incorporation of CD55/decay-accelerating factor into viral particles bearing baculovirus GP64. J. Virol. 2010, 84:3210-3219.
24. Kenoutis C., Efrose R.C., Swevers L., Lavdas A.A., Gaitanou M., Matsas R., Iatrou K. Baculovirus-mediated gene delivery into mammalian cells does not alter their transcriptional and differentiating potential but is accompanied by early viral gene expression. J. Virol. 2006, 80:4135-4146.
25. Kitagawa Y., Tani H., Limn C.K., Matsunaga T.M., Moriishi K., Matsuura Y. Ligand-directed gene targeting to mammalian cells by pseudotype baculoviruses. J. Virol. 2005, 79:3639-3652.
26. Koelle M.R., Talbot W.S., Segraves W.A., Bender M.T., Cherbas P., Hogness D.S. The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell 1991, 67:59-77.
27. Kondo A., Maeda S. Host range expansion by recombination of the baculoviruses Bombyx mori nuclear polyhedrosis virus and Autographa californica nuclear polyhedrosis virus. J. Virol. 1991, 65:3625-3632.
28. Kovacs G.R., Guarino L.A., Summers M.D. Novel regulatory properties of the IE1 and IE0 transactivators encoded by the baculovirus Autographa californica multicapsid nuclear polyhedrosis virus. J. Virol. 1991, 65:5281-5288.
29. Laakkonen J.P., Kaikkonen M.U., Ronkainen P.H., Ihalainen T.O., Niskanen E.A., Hakkinen M., Salminen M., Kulomaa M.S., Yla-Herttuala S., Airenne K.J., Vihinen-Ranta M. Baculovirus-mediated immediate-early gene expression and nuclear reorganization in human cells. Cell. Microbiol. 2008, 10:667-681.
30. Laakkonen J.P., Mäkelä A.R., Kakkonen E., Turkki P., Kukkonen S., Peränen J., Ylä-Herttuala S., Airenne K.J., Oker-Blom C., Vihinen-Ranta M., Marjomäki V. Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells. PLoS ONE 2009, 4:e5093.
31. Labropoulou V., Douris V., Stefanou D., Magrioti C., Swevers L., Iatrou K. Endoparasitoid wasp bracovirus-mediated inhibition of hemolin function and lepidopteran host immunosuppression. Cell. Microbiol. 2008, 10:2118-2128.
32. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
33. Leisy D.J., Rasmussen C., Owusu E.O., Rohrmann G.F. A mechanism for negative gene regulation in Autographa californica multinucleocapsid nuclear polyhedrosis virus. J. Virol. 1997, 71:5088-5094.
34. Liu C.Y., Wang C.H., Wang J.C., Chao Y.C. Stimulation of baculovirus transcriptome expression in mammalian cells by baculoviral transcriptional activators. J. Gen. Virol. 2007, 88:2176-2184.
35. Lo H.R., Chao Y.C. Rapid titer determination of baculovirus by quantitative real-time polymerase chain reaction. Biotechnol. Prog. 2004, 20:354-360.
36. Lu M., Farrell P.J., Johnson R., Iatrou K. A baculovirus (Bombyx mori nuclear polyhedrosis virus) repeat element functions as a powerful constitutive enhancer in transfected insect cells. J. Biol. Chem. 1997, 272:30724-30728.
37. Maeda S., Kamita S.G., Kondo A. Host range expansion of Autographa californica nuclear polyhedrosis virus (NPV) following recombination of a 0.6-kilobase-pair DNA fragment originating from Bombyx mori NPV. J. Virol. 1993, 67:6234-6238.
38. Monsma S.A., Oomens A.G., Blissard G.W. The GP64 envelope fusion protein is an essential baculovirus protein required for cell-to-cell transmission of infection. J. Virol. 1996, 70:4607-4616.
39. O'Reilly D.R., Miller L.K., Luckow V.A. Baculovirus expression vectors: a laboratory manual 1992, W.H. Freeman and Co, New York City.
40. Pathakamuri J.A., Theilmann D.A. The acidic activation domain of the baculovirus transactivator IE1 contains a virus-specific domain essential for DNA replication. J. Virol. 2002, 76:5598-5604.
41. Prikhod'ko E.A., Miller L.K. Induction of apoptosis by baculovirus transactivator IE1. J. Virol. 1996, 70:7116-7124.
42. Ramakers C., Ruijter J.M., Deprez R.H., Moorman A.F. Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci. Lett. 2003, 339:62-66.
43. Schultz K.L., Wetter J.A., Fiore D.C., Friesen P.D. Transactivator IE1 is required for baculovirus early replication events that trigger apoptosis in permissive and nonpermissive cells. J. Virol. 2009, 83:262-272.
44. Slack J.M., Blissard G.W. Identification of two independent transcriptional activation domains in the Autographa californica multicapsid nuclear polyhedrosis virus IE1 protein. J. Virol. 1997, 71:9579-9587.
45. Spenger A., Ernst W., Condreay J.P., Kost T.A., Grabherr R. Influence of promoter choice and trichostatin A treatment on expression of baculovirus delivered genes in mammalian cells. Protein Expr. Purif. 2004, 38:17-23.
46. Stewart T.M., Huijskens I., Willis L.G., Theilmann D.A. The Autographa californica multiple nucleopolyhedrovirus ie0-ie1 gene complex is essential for wild-type virus replication, but either IE0 or IE1 can support virus growth. J. Virol. 2005, 79:4619-4629.
47. van Loo N.D., Fortunati E., Ehlert E., Rabelink M., Grosveld F., Scholte B.J. Baculovirus infection of nondividing mammalian cells: mechanisms of entry and nuclear transport of capsids. J. Virol. 2001, 75:961-970.
48. van Oers M.M. Vaccines for viral and parasitic diseases produced with baculovirus vectors. Adv. Virus Res. 2006, 68:193-253.
49. Vaughn J.L., Goodwin R.H., Tompkins G.J., McCawley P. The establishment of two cell lines from the insect Spodoptera frugiperda (Lepidoptera; Noctuidae). In Vitro 1977, 13:213-217.