메뉴 건너뛰기




Volumn 34, Issue 5 PART 2, 2011, Pages

Identification and characterization of a novel Rab GTPase-activating protein in spermatids

Author keywords

GAP; MgcRabGAP; Spermatogenesis; Testis

Indexed keywords

BETA ACTIN; CELL PROTEIN; MALE GERM CELLS RAB GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RAB PROTEIN; UNCLASSIFIED DRUG;

EID: 80053432970     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2010.01126.x     Document Type: Article
Times cited : (23)

References (48)
  • 1
    • 0026644240 scopus 로고
    • A Drosophila rotund transcript expressed during spermatogenesis and imaginal disc morphogenesis encodes a protein which is similar to human Rac GTPase-activating (racGap) proteins
    • Agnel M, Roder L, Vola C & Griffin-Shea R. (1992) A Drosophila rotund transcript expressed during spermatogenesis and imaginal disc morphogenesis encodes a protein which is similar to human Rac GTPase-activating (racGap) proteins. Mol Cell Biol 12, 5111-5122.
    • (1992) Mol Cell Biol , vol.12 , pp. 5111-5122
    • Agnel, M.1    Roder, L.2    Vola, C.3    Griffin-Shea, R.4
  • 2
    • 0033923318 scopus 로고    scopus 로고
    • Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific gap
    • Albert S & Gallwitz D. (2000) Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific gap. Biol Chem 381, 453-456.
    • (2000) Biol Chem , vol.381 , pp. 453-456
    • Albert, S.1    Gallwitz, D.2
  • 3
    • 0033214775 scopus 로고    scopus 로고
    • Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases
    • Albert S, Will E & Gallwitz D. (1999) Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases. EMBO J 18, 5216-5225.
    • (1999) EMBO J , vol.18 , pp. 5216-5225
    • Albert, S.1    Will, E.2    Gallwitz, D.3
  • 4
    • 77953195622 scopus 로고    scopus 로고
    • Tbc1d1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle
    • An D, Toyoda T, Taylor EB, Yu H, Fujii N, Hirshman MF & Goodyear LJ. (2010) Tbc1d1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle. Diabetes 59, 1358-1365.
    • (2010) Diabetes , vol.59 , pp. 1358-1365
    • An, D.1    Toyoda, T.2    Taylor, E.B.3    Yu, H.4    Fujii, N.5    Hirshman, M.F.6    Goodyear, L.J.7
  • 5
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: critical elements in the control of small G proteins
    • Bos JL, Rehmann H & Wittinghofer A. (2007) GEFs and GAPs: critical elements in the control of small G proteins. Cell 129, 865-877.
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 6
    • 15844363885 scopus 로고    scopus 로고
    • Role of actin cytoskeleton in mammalian sperm capacitation and the acrosome reaction
    • Breitbart H, Cohen G & Rubinstein S. (2005) Role of actin cytoskeleton in mammalian sperm capacitation and the acrosome reaction. Reproduction 129, 263-268.
    • (2005) Reproduction , vol.129 , pp. 263-268
    • Breitbart, H.1    Cohen, G.2    Rubinstein, S.3
  • 7
    • 0037369769 scopus 로고    scopus 로고
    • Remodeling of the actin cytoskeleton during mammalian sperm capacitation and acrosome reaction
    • Brener E, Rubinstein S, Cohen G, Shternall K, Rivlin J & Breitbart H. (2003) Remodeling of the actin cytoskeleton during mammalian sperm capacitation and acrosome reaction. Biol Reprod 68, 837-845.
    • (2003) Biol Reprod , vol.68 , pp. 837-845
    • Brener, E.1    Rubinstein, S.2    Cohen, G.3    Shternall, K.4    Rivlin, J.5    Breitbart, H.6
  • 8
    • 35648942810 scopus 로고    scopus 로고
    • IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1, and Cdc42
    • Brown MD, Bry L, Li Z & Sacks DB. (2007) IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1, and Cdc42. J Biol Chem 282, 30265-30272.
    • (2007) J Biol Chem , vol.282 , pp. 30265-30272
    • Brown, M.D.1    Bry, L.2    Li, Z.3    Sacks, D.B.4
  • 9
    • 0026657024 scopus 로고
    • Evidence for decreasing quality of semen during past 50years
    • Carlsen E, Giwercman A, Keiding N & Skakkebaek NE. (1992) Evidence for decreasing quality of semen during past 50years. BMJ 305, 609-613.
    • (1992) BMJ , vol.305 , pp. 609-613
    • Carlsen, E.1    Giwercman, A.2    Keiding, N.3    Skakkebaek, N.E.4
  • 11
    • 0032433099 scopus 로고    scopus 로고
    • Myr 7 is a novel myosin IX-RhoGAP expressed in rat brain
    • Chieregatti E, Gartner A, Stoffler HE & Bahler M. (1998) Myr 7 is a novel myosin IX-RhoGAP expressed in rat brain. J Cell Sci 111, 3597-3608.
    • (1998) J Cell Sci , vol.111 , pp. 3597-3608
    • Chieregatti, E.1    Gartner, A.2    Stoffler, H.E.3    Bahler, M.4
  • 12
    • 36649020854 scopus 로고    scopus 로고
    • The Macaque sperm actin cytoskeleton reorganizes in response to osmotic stress and contributes to morphological defects and decreased motility
    • Correa LM, Thomas A & Meyers SA. (2007) The Macaque sperm actin cytoskeleton reorganizes in response to osmotic stress and contributes to morphological defects and decreased motility. Biol Reprod 77, 942-953.
    • (2007) Biol Reprod , vol.77 , pp. 942-953
    • Correa, L.M.1    Thomas, A.2    Meyers, S.A.3
  • 13
    • 3042561479 scopus 로고    scopus 로고
    • Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells
    • Curry BJ, Su H, Law EG, McLaughlin EA, Nixon B & Aitken RJ. (2004) Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells. Genomics 84, 406-418.
    • (2004) Genomics , vol.84 , pp. 406-418
    • Curry, B.J.1    Su, H.2    Law, E.G.3    McLaughlin, E.A.4    Nixon, B.5    Aitken, R.J.6
  • 15
    • 0041475853 scopus 로고    scopus 로고
    • The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization
    • Gao XD, Albert S, Tcheperegine SE, Burd CG, Gallwitz D & Bi E. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162, 635-646.
    • (2003) J Cell Biol , vol.162 , pp. 635-646
    • Gao, X.D.1    Albert, S.2    Tcheperegine, S.E.3    Burd, C.G.4    Gallwitz, D.5    Bi, E.6
  • 16
    • 0027282112 scopus 로고
    • Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the Ras-related protein p21Rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes
    • Hall C, Sin WC, Teo M, Michael GJ, Smith P, Dong JM et al. (1993) Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the Ras-related protein p21Rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes. Mol Cell Biol 13, 4986-4998.
    • (1993) Mol Cell Biol , vol.13 , pp. 4986-4998
    • Hall, C.1    Sin, W.C.2    Teo, M.3    Michael, G.J.4    Smith, P.5    Dong, J.M.6
  • 17
    • 0033168842 scopus 로고    scopus 로고
    • Identification of Rab3a GTPase as an acrosome-associated small GTP-binding protein in rat sperm
    • Iida H, Yoshinaga Y, Tanaka S, Toshimori K & Mori T. (1999) Identification of Rab3a GTPase as an acrosome-associated small GTP-binding protein in rat sperm. Dev Biol 211, 144-155.
    • (1999) Dev Biol , vol.211 , pp. 144-155
    • Iida, H.1    Yoshinaga, Y.2    Tanaka, S.3    Toshimori, K.4    Mori, T.5
  • 18
    • 13444302486 scopus 로고    scopus 로고
    • The acrosome-acroplaxome-manchette complex and the shaping of the spermatid head
    • Kierszenbaum AL & Tres LL. (2004) The acrosome-acroplaxome-manchette complex and the shaping of the spermatid head. Arch Histol Cytol 67, 271-284.
    • (2004) Arch Histol Cytol , vol.67 , pp. 271-284
    • Kierszenbaum, A.L.1    Tres, L.L.2
  • 19
    • 0344392821 scopus 로고    scopus 로고
    • Acroplaxome, an F-actin-keratin-containing plate, anchors the acrosome to the nucleus during shaping of the spermatid head
    • Kierszenbaum AL, Rivkin E & Tres LL. (2003a) Acroplaxome, an F-actin-keratin-containing plate, anchors the acrosome to the nucleus during shaping of the spermatid head. Mol Biol Cell 14, 4628-4640.
    • (2003) Mol Biol Cell , vol.14 , pp. 4628-4640
    • Kierszenbaum, A.L.1    Rivkin, E.2    Tres, L.L.3
  • 20
    • 1842580500 scopus 로고    scopus 로고
    • The actin-based motor myosin Va is a component of the acroplaxome, an acrosome-nuclear envelope junctional plate, and of manchette-associated vesicles
    • Kierszenbaum AL, Rivkin E & Tres LL. (2003b) The actin-based motor myosin Va is a component of the acroplaxome, an acrosome-nuclear envelope junctional plate, and of manchette-associated vesicles. Cytogenet Genome Res 103, 337-344.
    • (2003) Cytogenet Genome Res , vol.103 , pp. 337-344
    • Kierszenbaum, A.L.1    Rivkin, E.2    Tres, L.L.3
  • 21
    • 0037388746 scopus 로고    scopus 로고
    • Rab8b GTPase and junction dynamics in the testis
    • Lau AS & Mruk DD. (2003) Rab8b GTPase and junction dynamics in the testis. Endocrinology 144, 1549-1563.
    • (2003) Endocrinology , vol.144 , pp. 1549-1563
    • Lau, A.S.1    Mruk, D.D.2
  • 23
    • 0028180706 scopus 로고
    • Cerebellar beta2-chimaerin, a GTPase-activating protein for p21 Ras-related Rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain
    • Leung T, How BE, Manser E & Lim L. (1994) Cerebellar beta2-chimaerin, a GTPase-activating protein for p21 Ras-related Rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain. J Biol Chem 269, 12888-12892.
    • (1994) J Biol Chem , vol.269 , pp. 12888-12892
    • Leung, T.1    How, B.E.2    Manser, E.3    Lim, L.4
  • 24
    • 33751197489 scopus 로고    scopus 로고
    • Identification of ten novel genes involved in human spermatogenesis by microarray analysis of testicular tissue
    • Lin YH, Lin YM, Teng YN, Hsieh TY, Lin YS & Kuo PL. (2006a) Identification of ten novel genes involved in human spermatogenesis by microarray analysis of testicular tissue. Fertil Steril 86, 1650-1658.
    • (2006) Fertil Steril , vol.86 , pp. 1650-1658
    • Lin, Y.H.1    Lin, Y.M.2    Teng, Y.N.3    Hsieh, T.Y.4    Lin, Y.S.5    Kuo, P.L.6
  • 25
    • 29144447446 scopus 로고    scopus 로고
    • Decreased mRNA transcripts of M-phase promoting factor and its regulators in the testes of infertile men
    • Lin YM, Teng YN, Chung CL, Tsai WC, Lin YH, Lin JS & Kuo PL. (2006b) Decreased mRNA transcripts of M-phase promoting factor and its regulators in the testes of infertile men. Hum Reprod 21, 138-144.
    • (2006) Hum Reprod , vol.21 , pp. 138-144
    • Lin, Y.M.1    Teng, Y.N.2    Chung, C.L.3    Tsai, W.C.4    Lin, Y.H.5    Lin, J.S.6    Kuo, P.L.7
  • 26
    • 65649118958 scopus 로고    scopus 로고
    • The expression level of septin12 is critical for spermiogenesis
    • Lin YH, Lin YM, Wang YY, Yu IS, Lin YW, Wang YH et al. (2009) The expression level of septin12 is critical for spermiogenesis. Am J Pathol 174, 1857-1868.
    • (2009) Am J Pathol , vol.174 , pp. 1857-1868
    • Lin, Y.H.1    Lin, Y.M.2    Wang, Y.Y.3    Yu, I.S.4    Lin, Y.W.5    Wang, Y.H.6
  • 27
    • 10044238907 scopus 로고    scopus 로고
    • Interactions among IQGAP1, Cdc42, and the cadherin/catenin protein complex regulate Sertoli-germ cell adherens junction dynamics in the testis
    • Lui WY, Mruk DD & Cheng CY. (2005) Interactions among IQGAP1, Cdc42, and the cadherin/catenin protein complex regulate Sertoli-germ cell adherens junction dynamics in the testis. J Cell Physiol 202, 49-66.
    • (2005) J Cell Physiol , vol.202 , pp. 49-66
    • Lui, W.Y.1    Mruk, D.D.2    Cheng, C.Y.3
  • 28
    • 0037372202 scopus 로고    scopus 로고
    • The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling
    • Masuda-Robens JM, Kutney SN, Qi H & Chou MM. (2003) The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling. Mol Cell Biol 23, 2151-2161.
    • (2003) Mol Cell Biol , vol.23 , pp. 2151-2161
    • Masuda-Robens, J.M.1    Kutney, S.N.2    Qi, H.3    Chou, M.M.4
  • 29
    • 55549115368 scopus 로고    scopus 로고
    • The biology of infertility: research advances and clinical challenges
    • Matzuk MM & Lamb DJ. (2008) The biology of infertility: research advances and clinical challenges. Nat Med 14, 1197-1213.
    • (2008) Nat Med , vol.14 , pp. 1197-1213
    • Matzuk, M.M.1    Lamb, D.J.2
  • 31
    • 48749124899 scopus 로고    scopus 로고
    • Rab2a: a major subacrosomal protein of bovine spermatozoa implicated in acrosomal biogenesis
    • Mountjoy JR, Xu W, McLeod D, Hyndman D & Oko R. (2008) Rab2a: a major subacrosomal protein of bovine spermatozoa implicated in acrosomal biogenesis. Biol Reprod 79, 223-232.
    • (2008) Biol Reprod , vol.79 , pp. 223-232
    • Mountjoy, J.R.1    Xu, W.2    McLeod, D.3    Hyndman, D.4    Oko, R.5
  • 32
    • 0030810986 scopus 로고    scopus 로고
    • Regulation of membrane stability and the acrosome reaction in mammalian sperm
    • Nolan JP & Hammerstedt RH. (1997) Regulation of membrane stability and the acrosome reaction in mammalian sperm. FASEB J 11, 670-682.
    • (1997) FASEB J , vol.11 , pp. 670-682
    • Nolan, J.P.1    Hammerstedt, R.H.2
  • 34
    • 33746356908 scopus 로고    scopus 로고
    • TBC-domain gaps for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism
    • Pan X, Eathiraj S, Munson M & Lambright DG. (2006) TBC-domain gaps for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. Nature 442, 303-306.
    • (2006) Nature , vol.442 , pp. 303-306
    • Pan, X.1    Eathiraj, S.2    Munson, M.3    Lambright, D.G.4
  • 36
    • 0034785031 scopus 로고    scopus 로고
    • Targeting and fusion proteins during mammalian spermiogenesis
    • Ramalho-Santos J & Moreno RD. (2001) Targeting and fusion proteins during mammalian spermiogenesis. Biol Res 34, 147-152.
    • (2001) Biol Res , vol.34 , pp. 147-152
    • Ramalho-Santos, J.1    Moreno, R.D.2
  • 37
    • 3242878004 scopus 로고    scopus 로고
    • A screen for modifiers of RacGAP(84c) gain-of-function in the Drosophila eye revealed the LIM kinase Cdi/TESK1 as a downstream effector of Rac1 during spermatogenesis
    • Raymond K, Bergeret E, Avet-Rochex A, Griffin-Shea R & Fauvarque MO. (2004) A screen for modifiers of RacGAP(84c) gain-of-function in the Drosophila eye revealed the LIM kinase Cdi/TESK1 as a downstream effector of Rac1 during spermatogenesis. J Cell Sci 117, 2777-2789.
    • (2004) J Cell Sci , vol.117 , pp. 2777-2789
    • Raymond, K.1    Bergeret, E.2    Avet-Rochex, A.3    Griffin-Shea, R.4    Fauvarque, M.O.5
  • 38
    • 0031777019 scopus 로고    scopus 로고
    • NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4s neuroblastoma
    • Roberts T, Chernova O & Cowell JK. (1998) NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4s neuroblastoma. Hum Mol Genet 7, 1169-1178.
    • (1998) Hum Mol Genet , vol.7 , pp. 1169-1178
    • Roberts, T.1    Chernova, O.2    Cowell, J.K.3
  • 40
    • 0034460293 scopus 로고    scopus 로고
    • Evaluation and treatment of male infertility
    • Silber SJ. (2000) Evaluation and treatment of male infertility. Clin Obstet Gynecol 43, 854-888.
    • (2000) Clin Obstet Gynecol , vol.43 , pp. 854-888
    • Silber, S.J.1
  • 41
    • 33748745768 scopus 로고    scopus 로고
    • TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition
    • Stone S, Abkevich V, Russell DL, Riley R, Timms K, Tran T et al. (2006) TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition. Hum Mol Genet 15, 2709-2720.
    • (2006) Hum Mol Genet , vol.15 , pp. 2709-2720
    • Stone, S.1    Abkevich, V.2    Russell, D.L.3    Riley, R.4    Timms, K.5    Tran, T.6
  • 43
    • 77957372722 scopus 로고    scopus 로고
    • Expression of Lrwd1 in mouse testis and its centrosomal localization
    • Teng YN, Liao MH, Lin YB, Kuo PL & Kuo TY. (2010) Expression of Lrwd1 in mouse testis and its centrosomal localization. Int J Androl 33, 1-9.
    • (2010) Int J Androl , vol.33 , pp. 1-9
    • Teng, Y.N.1    Liao, M.H.2    Lin, Y.B.3    Kuo, P.L.4    Kuo, T.Y.5
  • 44
    • 0032513234 scopus 로고    scopus 로고
    • MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells
    • Toure A, Dorseuil O, Morin L, Timmons P, Jegou B, Reibel L & Gacon G. (1998) MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells. J Biol Chem 273, 6019-6023.
    • (1998) J Biol Chem , vol.273 , pp. 6019-6023
    • Toure, A.1    Dorseuil, O.2    Morin, L.3    Timmons, P.4    Jegou, B.5    Reibel, L.6    Gacon, G.7
  • 45
    • 0024891608 scopus 로고
    • Distribution and function of organized concentrations of actin filaments in mammalian spermatogenic cells and sertoli cells
    • Vogl AW. (1989) Distribution and function of organized concentrations of actin filaments in mammalian spermatogenic cells and sertoli cells. Int Rev Cytol 119, 1-56.
    • (1989) Int Rev Cytol , vol.119 , pp. 1-56
    • Vogl, A.W.1
  • 46
    • 11144281842 scopus 로고    scopus 로고
    • Cloning and characterization of a novel transcript variant of IQGAP2 in human testis
    • Wang H, Huo R, Xu M, Lu L, Xu Z, Li J, Zhou Z & Sha J. (2004) Cloning and characterization of a novel transcript variant of IQGAP2 in human testis. DNA Seq 15, 319-325.
    • (2004) DNA Seq , vol.15 , pp. 319-325
    • Wang, H.1    Huo, R.2    Xu, M.3    Lu, L.4    Xu, Z.5    Li, J.6    Zhou, Z.7    Sha, J.8
  • 48
    • 0025088833 scopus 로고
    • A quantitative study of spermatogenesis in the developing rat testis
    • Yang ZW, Wreford NG & de Kretser DM. (1990) A quantitative study of spermatogenesis in the developing rat testis. Biol Reprod 43, 629-635.
    • (1990) Biol Reprod , vol.43 , pp. 629-635
    • Yang, Z.W.1    Wreford, N.G.2    de Kretser, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.