Feasibility and safety of long-term photodynamic therapy (PDT) in the palliative treatment of patients with hilar cholangiocarcinoma

European Journal of Medical Research

Volumn 16, Issue 9, 2011, Pages 391-395

  Höblinger, Aksana ^a   Gerhardt, T ^a   Gonzalez Carmona M A ^a   Huneburg R ^a   Sauerbruch, T ^a   Schmitz, V ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Chemotherapy; Cholangiocarcinoma; Palliative care; Photodynamic therapy

Indexed keywords

BILIRUBIN; CETUXIMAB; CISPLATIN; GEMCITABINE; OXALIPLATIN; PHOTOFRIN;

ADULT; AGED; ARTICLE; BILE DUCT CARCINOMA; BILIARY TRACT DRAINAGE; BILIRUBIN BLOOD LEVEL; CLINICAL ARTICLE; DRUG DOSE REDUCTION; FEASIBILITY STUDY; FEMALE; HILAR CHOLANGIOCARCINOMA; HUMAN; LONG TERM CARE; MALE; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PALLIATIVE THERAPY; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; POLYNEUROPATHY; RADIATION SAFETY; RETROSPECTIVE STUDY; SKIN MANIFESTATION; STENT; BILIARY STENT; CANCER COMBINATION CHEMOTHERAPY; CANCER PALLIATIVE THERAPY; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; ENDOSCOPIC SURGERY; EXTRAHEPATIC CHOLANGIOCARCINOMA; METAL STENT; MIDDLE AGED; PATIENT SAFETY; PHOTODERMATOSIS; PHOTODYNAMIC THERAPY DEVICE; PLASTIC STENT; SURVIVAL TIME; VERY ELDERLY;

EID: 80053419003     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: 10.1186/2047-783x-16-9-391     Document Type: Article

References (18)

1. Aljiffry M, Walsh MJ, Molinari M. Advances in diagnosis, treatment and palliation of cholangiocarcinoma: 1990-2009. World J Gastroenterol. 2009 Sep 14; 15(34): 4240-62.
2. Ortner MA. Photodynamic therapy for cholangiocarcinoma: overview and new developments. Curr Opin Gastroenterol. 2009 Sep; 25(5): 472-6.
3. Juarranz A, Jaén P, Sanz-Rodríguez F, Cuevas J, González S. Photodynamic therapy of cancer. Basic principles and applications. Clin Transi Oncol. 2008 Mar; 10(3): 148-54.
4. Ortner MA, Liebetruth J, Schreiber S, Hanft M, Wruck U, Fusco V, Müller JM, Hörtnagl H, Lochs H. Photodynamic therapy of nonresectable cholangiocarcinoma. Gastroenterology. 1998 Mar; 114(3): 536-42.
5. Berr F, Wiedmann M, Tannapfel A, Halm U, Kohlhaw KR, Schmidt F, Wittekind C, Hauss J, Mössner J. Photodynamic therapy for advanced bile duct cancer: evidence for improved palliation and extended survival. Hepatology. 2000 Feb; 31(2): 291-8. (Pubitemid 30078590)
6. Zoepf T, Jakobs R, Arnold JC, Apel D, Rosenbaum A, Riemann JF. Photodynamic therapy for palliation of nonresectable bile duct cancer - preliminary results with a new diode laser system. Am J Gastroenterol. 2001 Jul; 96(7): 2093-7. (Pubitemid 32660902)
7. Rumalla A, Baron TH, Wang KK, Gores GJ, Stadheim LM, De Groen PC. Endoscopic application of photodynamic therapy for cholangiocarcinoma. Gastrointest Endosc. 2001 Apr; 53(4): 500-4. (Pubitemid 33586760)
8. Dumoulin FL, Gerhardt T, Fuchs S, Scheurlen C, Neubrand M, Layer G, Sauerbruch T. Phase II study of photodynamic therapy and metal stent as palliative treatment for nonresectable hilar cholangiocarcinoma. Gastrointest Endosc. 2003 Jun; 57(7):860-7. (Pubitemid 47231345)
9. Ortner ME, Caca K, Berr F, Liebetruth J, Mansmann U, Huster D, Voderholzer W, Schachschal G, Mössner J, Lochs H. Successful photodynamic therapy for nonresectable cholangiocarcinoma: a randomized prospective study. Gastroenterology. 2003 Nov; 125(5):1355-63. (Pubitemid 37409755)
10. Harewood GC, Baron TH, Rumalla A, Wang KK, Gores GJ, Stadheim LM, De Groen PC. Pilot study to assess patient outcomes following endoscopic application of photodynamic therapy for advanced cholangiocarcinoma. J Gastroenterol Hepatol. 2005 Mar; 20(3):415-20. (Pubitemid 40469343)
11. Shim CS, Cheon YK, Cha SW, Bhandari S, Moon JH, Cho YD, Kim YS, Lee LS, Lee MS, Kim BS. Prospective study of the effectiveness of percutaneous transhepatic photodynamic therapy for advanced bile duct cancer and the role of intraductal ultrasonography in response assessment. Endoscopy. 2005 May; 37(5): 425-33. (Pubitemid 40668207)
12. Zoepf T, Jakobs R, Arnold JC, Apel D, Riemann JF. Palliation of nonresectable bile duct cancer: improved survival after photodynamic therapy. Am J Gastroenterol. 2005 Nov; 100(11): 2426-30.
13. Witzigmann H, Berr F, Ringel U, Caca K, Uhlmann D, Schoppmeyer K, Tannapfel A, Wittekind C, Mossner J, Hauss J, Wiedmann M. Surgical and palliative management and outcome in 184 patients with hilar cholangiocarcinoma: palliative photodynamic therapy plus stenting is comparable to r1/r2 resection. Ann Surg. 2006 Aug; 244(2): 230-9. (Pubitemid 44305537)
14. Gollnick SO and Brackett CM. Enhancement of anti-tumor immunity by photodynamic therapy. Immunol Res. 2010 Mar; 46(1-3):216-26.
15. Prasad GA, Wang KK, Baron TH, Buttar NS, Wongkeesong LM, Roberts LR, LeRoy AJ, Lutzke LS, Borkenhagen LS. Factors associated with increased survival after photodynamic therapy for cholangiocarcinoma. Clin Gastroenterol Hepatol. 2007 Jun; 5(6):743-8. (Pubitemid 46830054)
16. Fuks D, Bartoli E, Delcenserie R, Yzet T, Celice P, Sabbagh C, Chatelain D, Joly JP, Cheron N, Dupas JL, Regimbeau JM. Biliary drainage, photodynamic therapy and chemotherapy for unresectable cholangiocarcinoma with jaundice. J Gastroenterol Hepatol. 2009 Nov; 24(11): 1745-52.
17. Gerhardt T, Rings D, Höblinger A, Heller J, Sauerbruch T, Schepke M. Combination of bilateral metal stenting and trans-stent photodynamic therapy for palliative treatment of hilar cholangiocarcinoma. Z Gastroenterol. 2010 Jan; 48(1): 28-32.
18. Juntermanns B, Radunz S, Heuer M, Hertel S, Reis H, Neuhaus JP, Vernadakis S, Trarbach T, Paul A, Kaiser GM. Tumor markers as a diagnostic key for hilar cholangiocarcinoma. Eur J Med Res. 2010 Aug 20;15(8):357-61.