Drug penetration of the posterior eye tissues after topical instillation: In vivo and in silico simulation

Chemical and Pharmaceutical Bulletin

Volumn 59, Issue 10, 2011, Pages 1263-1267

  Shikamura, Yuko ^a,b   Ohtori, Akira ^a,b   Tojo, Kakuji ^b  

^a SENJU PHARMACEUTICAL CO LTD   (Japan)

^b KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Diffusion; Ocular pharmacokinetics; Ofloxacin; Topical; Vitreous body

Indexed keywords

OFLOXACIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CHOROID; COMPUTER MODEL; CONJUNCTIVA; CORNEA; DRUG PENETRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; IRIS; LACRIMAL FLUID; NONHUMAN; POSTERIOR EYE SEGMENT; RABBIT; RETINA; SCLERA; VITREOUS BODY;

ADMINISTRATION, TOPICAL; ANIMALS; ANTERIOR EYE SEGMENT; ANTI-BACTERIAL AGENTS; AQUEOUS HUMOR; COMPUTER SIMULATION; CORNEA; DIFFUSION; EYE; OFLOXACIN; RABBITS; SCLERA; VITREOUS BODY;

EID: 80053396260     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.59.1263     Document Type: Article

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