Effects of Tai Chi Chuan on insulin and cytokine levels in a randomized controlled pilot study on breast cancer survivors

Clinical Breast Cancer

Volumn 11, Issue 3, 2011, Pages 161-170

  Janelsins, Michelle C ^a   Davis, Paul G ^b   Wideman, Laurie ^b   Katula, Jeffrey A ^c   Sprod, Lisa K ^a   Peppone, Luke J ^a   Palesh, Oxana G ^d   Heckler, Charles E ^a   Williams, Jacqueline P ^a   Morrow, Gary R ^a   Mustian, Karen M ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^c WAKE FOREST UNIVERSITY   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biomarkers; Cytokines; Insulin; Survivorship; Tai chi chuan; Weight gain

Indexed keywords

GAMMA INTERFERON; INSULIN; INTERLEUKIN 2; INTERLEUKIN 6; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; CYTOKINE;

ADULT; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVOR; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORRELATIONAL STUDY; FEMALE; HUMAN; INSULIN BLOOD LEVEL; MASTECTOMY; PARTIAL MASTECTOMY; PHYSICAL ACTIVITY; PILOT STUDY; PROTEIN BLOOD LEVEL; PSYCHOSOCIAL CARE; RANDOMIZED CONTROLLED TRIAL; TAI CHI; TREATMENT DURATION; AGED; BLOOD; BREAST TUMOR; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; MIDDLE AGED; MORTALITY; PATHOPHYSIOLOGY; SURVIVOR;

ADULT; AGED; BREAST NEOPLASMS; CYTOKINES; FEMALE; HUMANS; INSULIN; MIDDLE AGED; PILOT PROJECTS; SURVIVORS; TAI JI;

EID: 80053393681     PISSN: 15268209     EISSN: 19380666     Source Type: Journal    
DOI: 10.1016/j.clbc.2011.03.013     Document Type: Article

References (46)

1. Demark-Wahnefried W, Rimer BK, Winer EP. Weight gain in women diagnosed with breast cancer. J Am Diet Assoc 1997; 97:519-26, 29; quiz 27-8. (Pubitemid 27194773)
2. Heideman WH, Russell NS, Gundy C, et al. The frequency, magnitude and timing of post-diagnosis body weight gain in Dutch breast cancer survivors. Eur J Cancer 2009; 45:119-26.
3. Boyd NF. Nutrition and breast cancer. J Natl Cancer Inst 1993; 85:6-7. (Pubitemid 23023210)
4. Tredan O, Bajard A, Meunier A, et al. Body weight change in women receiving adjuvant chemotherapy for breast cancer: A French prospective study. Clin Nutr 2010; 29:187-91.
5. Demark-Wahnefried W, Peterson BL, Winer EP, et al. Changes in weight, body composition, and factors influencing energy balance among premenopausal breast cancer patients receiving adjuvant chemotherapy. J Clin Oncol 2001; 19:2381-9. (Pubitemid 32391208)
6. Caan BJ, Emond JA, Natarajan L, et al. Post-diagnosis weight gain and breast cancer recurrence in women with early stage breast cancer. Breast Cancer Res Treat 2006; 99:47-57. (Pubitemid 44168602)
7. Nichols HB, Trentham-Dietz A, Egan KM, et al. Body mass index before and after breast cancer diagnosis: associations with all-cause, breast cancer, and cardiovascular disease mortality. Cancer Epidemiol Biomarkers Prev 2009; 18:1403-9.
8. Goodwin PJ, Ennis M, Pritchard KI, et al. Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study. J Clin Oncol 2002; 20:42-51. (Pubitemid 34032594)
9. Kleinberg DL, Wood TL, Furth PA, et al. Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions. Endocr Rev 2009; 30:51-74.
10. Aggarwal BB, Gehlot P. Inflammation and cancer: how friendly is the relationship for cancer patients? Curr Opin Pharmacol 2009; 9:351-69.
11. Holmes MD, Chen WY, Feskanich D, et al. Physical activity and survival after breast cancer diagnosis. JAMA 2005; 293:2479-86. (Pubitemid 40705729)
12. Abrahamson PE, Gammon MD, Lund MJ, et al. Recreational physical activity and survival among young women with breast cancer. Cancer 2006; 107:1777-85. (Pubitemid 44582946)
13. Irwin ML, Smith AW, McTiernan A, et al. Influence of pre-and postdiagnosis physical activity on mortality in breast cancer survivors: the health, eating, activity, and lifestyle study. J Clin Oncol 2008; 26:3958-64.
14. Speed-Andrews AE, Courneya KS. Effects of exercise on quality of life and prognosis in cancer survivors. Curr Sports Med Rep 2009; 8:176-81.
15. Ligibel JA, Campbell N, Partridge A, et al. Impact of a mixed strength and endurance exercise intervention on insulin levels in breast cancer survivors. J Clin Oncol 2008; 26:907-12. (Pubitemid 351398083)
16. Duncan GE, Perri MG, Theriaque DW, et al. Exercise training, without weight loss, increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults. Diabetes Care 2003; 26:557-62. (Pubitemid 36929307)
17. Schmitz KH, Ahmed RL, Yee D. Effects of a 9-month strength training intervention on insulin, insulin-like growth factor (IGF)-I, IGF-binding protein (IGFBP)-1, and IGFBP-3 in 30-50-year-old women. Cancer Epidemiol Biomarkers Prev 2002; 11:1597-604. (Pubitemid 36020013)
18. Fairey AS, Courneya KS, Field CJ, et al. Effects of exercise training on fasting insulin, insulin resistance, insulin-like growth factors, and insulin-like growth factor binding proteins in postmenopausal breast cancer survivors: a randomized controlled trial. Cancer Epidemiol Biomarkers Prev 2003; 12:721-7. (Pubitemid 36993161)
19. Irwin ML, McTiernan A, Bernstein L, et al. Relationship of obesity and physical activity with C-peptide, leptin, and insulin-like growth factors in breast cancer survivors. Cancer Epidemiol Biomarkers Prev 2005; 14:2881-8. (Pubitemid 43068820)
20. McTiernan A, Sorensen B, Yasui Y, et al. No effect of exercise on insulin-like growth factor 1 and insulin-like growth factor binding protein 3 in postmenopausal women: a 12-month randomized clinical trial. Cancer Epidemiol Biomarkers Prev 2005; 14:1020-1. (Pubitemid 40478576)
21. Irwin ML, Varma K, Alvarez-Reeves M, et al. Randomized controlled trial of aerobic exercise on insulin and insulin-like growth factors in breast cancer survivors: the Yale Exercise and Survivorship study. Cancer Epidemiol Biomarkers Prev 2009; 18:306-13.
22. Speck RM, Courneya KS, Masse LC, et al. An update of controlled physical activity trials in cancer survivors: a systematic review and meta-analysis. J Cancer Surviv 2010; 4:87-100.
23. Mathur N, Pedersen BK. Exercise as a mean to control low-grade systemic inflammation. Mediators Inflamm 2008; 2008:109502.
24. Hiscock N, Chan MH, Bisucci T, et al. Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: evidence of fiber type specificity. FASEB J 2004; 18:992-4. (Pubitemid 39561502)
25. Starkie R, Ostrowski SR, Jauffred S, et al. Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. FASEB J 2003; 17:884-6.
26. Pedersen BK, Febbraio MA. Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev 2008; 88:1379-406.
27. Stewart LK, Flynn MG, Campbell WW, et al. The influence of exercise training on inflammatory cytokines and C-reactive protein. Med Sci Sports Exerc 2007; 39: 1714-9. (Pubitemid 47511477)
28. Rotter V, Nagaev I, Smith U. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 2003; 278:45777-84. (Pubitemid 37432722)
29. Yates JS, Mustian KM, Morrow GR, et al. Prevalence of complementary and alternative medicine use in cancer patients during treatment. Support Care Cancer 2005; 13:806-11. (Pubitemid 41414021)
30. Lengacher CA, Bennett MP, Kip KE, et al. Relief of symptoms, side effects, and psychological distress through use of complementary and alternative medicine in women with breast cancer. Oncol Nurs Forum 2006; 33:97-104. (Pubitemid 44870015)
31. Mansky P, Sannes T, Wallerstedt D, et al. Tai chi chuan: mind-body practice or exercise intervention? Studying the benefit for cancer survivors. Integr Cancer Ther 2006; 5:192-201. (Pubitemid 44154871)
32. Mustian KM, Katula JA, Gill DL, Roscoe JA, Lang D, Murphy K. Tai Chi Chuan, health-related quality of life and self-esteem: a randomized trial with breast cancer survivors. Support Care Cancer 2004; 12:871-6. (Pubitemid 40104783)
33. Mustian KM, Palesh OG, Flecksteiner SA. Tai Chi Chuan for breast cancer survivors. Med Sport Sci 2008; 52:209-17.
34. Mustian KM, Katula JA, Zhao H. A pilot study to assess the influence of tai chi chuan on functional capacity among breast cancer survivors. J Support Oncol 2006; 4:139-45.
35. Peppone LJ, Mustian KM, Janelsins MC, et al. Effects of a structured weightbearing exercise program on bone metabolism among breast cancer survivors: a feasibility trial. Clin Breast Cancer 2010; 10:224-9.
36. Oke SL, Tracey KJ. The inflammatory reflex and the role of complementary and alternative medical therapies. Ann N Y Acad Sci 2009; 1172:172-80.
37. Segal KR, Gutin B, Presta E, et al. Estimation of human body composition by electrical impedance methods: a comparative study. J Appl Physiol 1985; 58:1565-71. (Pubitemid 15027057)
38. Jiang XP, Yang DC, Elliott RL, et al. Reduction in serum IL-6 after vaccination of breast cancer patients with tumour-associated antigens is related to estrogen receptor status. Cytokine 2000; 12:458-65. (Pubitemid 30449843)
39. Walter M, Liang S, Ghosh S, et al. Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells. Oncogene 2009; 28:2745-55.
40. DeNardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res 2007; 9:212-22.
41. Pedersen BK, Steensberg A, Fischer C, et al. The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor? Proc Nutr Soc 2004; 63:263-7. (Pubitemid 38787476)
42. Petersen AM, Pedersen BK. The role of IL-6 in mediating the anti-inflammatory effects of exercise. J Physiol Pharmacol 2006; 57(suppl 10):43-51. (Pubitemid 46548766)
43. Kintscher U, Hartge M, Hess K, et al. T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Arterioscler Thromb Vasc Biol 2008; 28:1304-10.
44. Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15:914-20.
45. Yeh SH, Chuang H, Lin LW, et al. Regular tai chi chuan exercise enhances functional mobility and CD4CD25 regulatory T cells. Br J Sports Med 2006; 40:239-43. (Pubitemid 43384741)
46. Rocha VZ, Folco EJ, Sukhova G, et al. Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity. Circ Res 2008; 103:467-76.